- Article
Effect of Lactamase Inhibitors on the Biosensor Penp during the Measurement of Lactam Antibiotics Concentration
- Dagoberto Soto,
- Camila Silva,
- Cristian Ugalde,
- Kwok-Yin Wong,
- Yun-Chung Leung,
- Lok-Yan So and
- Max Andresen
PenP is a fluorescent biosensor of lactam antibiotics (LA). It is structurally derived from the mutant lactamase TEM-1 comprising the substitution E166C, where fluorescein is covalently linked to cysteine. The presence of LA in the medium produces a...

