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Molecules, Volume 27, Issue 2

2022 January-2 - 251 articles

Cover Story: In the past, the use of mechanochemical methods in organic synthesis was always reported as a bit of a curiosity. Recently, reactive extrusion has rapidly been established as a powerful tool enabling environmentally benign and sustainable chemical syntheses for its ability to perform continuous mechanochemical processes. Compared to conventional methods, reactive extrusion displays high simplicity, safety, and scalability, which can be exploited in a variety of chemical processes. Perspective applications ranging from organic synthesis to catalytic and active materials preparation could highlight the versatility of the technique and the huge potential of solid-phase flow chemistry. View this paper
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Articles (251)

  • Article
  • Open Access
22 Citations
5,558 Views
22 Pages

Beneficial Effects of Laurel (Laurus nobilis L.) and Myrtle (Myrtus communis L.) Extract on Rat Health

  • Marija Berendika,
  • Sandra Domjanić Drozdek,
  • Dyana Odeh,
  • Nada Oršolić,
  • Petar Dragičević,
  • Marijana Sokolović,
  • Ivona Elez Garofulić,
  • Domagoj Đikić and
  • Irena Landeka Jurčević

17 January 2022

Polyphenols of Laurel and Myrtle exhibit structural diversity, which affects bioavailability, metabolism, and bioactivity. The gut microbiota plays a key role in modulating the production, bioavailability and, thus the biological activities of phenol...

  • Article
  • Open Access
11 Citations
3,761 Views
12 Pages

Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst

  • Li-Guo Liao,
  • Meng-Meng Song,
  • Jun-Feng Feng,
  • Min Tan,
  • Fan Liu,
  • Zhen-Jiang Qiu,
  • Sheng Zhang and
  • Bang-Jing Li

17 January 2022

An efficient, mild, and green method was developed for the synthesis of indeno[1,2-b]quinoxaline derivatives via o-phenylenediamine (OPD) and 2-indanone derivatives utilizing β-cyclodextrin (β-CD) as the supramolecular catalyst. The reactio...

  • Article
  • Open Access
12 Citations
4,152 Views
12 Pages

17 January 2022

The aim of this study was to investigate the effects of the physical properties (diameter size, powder particle size, composition of bark- and wood-tissue, and turnover rate) and processing methods on the content of active ingredients in Astragali ra...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,615 Views
14 Pages

Structures of Dimer-of-Dimers Type Defect Cubane Tetranuclear Copper(II) Complexes with Novel Dinucleating Ligands

  • Ryusei Hoshikawa,
  • Ryoji Mitsuhashi,
  • Eiji Asato,
  • Jianqiang Liu and
  • Hiroshi Sakiyama

17 January 2022

Only a limited number of multinucleating ligands can stably maintain multinuclear metal structures in aqueous solutions. In this study, a water-soluble dinucleating ligand, 2,6-bis{[N-(carboxylatomethyl)-N-methyl-amino]methyl}-4-methylphenolate ((sym...

  • Article
  • Open Access
53 Citations
4,962 Views
19 Pages

Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

  • Amal Mohamed Al-Mohaimeed,
  • Wedad Altuhami Al-Onazi and
  • Maha Farouk El-Tohamy

17 January 2022

This work describes an environmental-friendly preparation of ZnO nanoparticles using aqueous oat extract. The advanced electrochemical and optical features of green synthesized ZnONPs displayed excellent antibacterial activity and exhibited an import...

  • Article
  • Open Access
31 Citations
4,788 Views
13 Pages

Evaluation of Antibacterial and Antifungal Properties of Low Molecular Weight Chitosan Extracted from Hermetia illucens Relative to Crab Chitosan

  • Adelya Khayrova,
  • Sergey Lopatin,
  • Balzhima Shagdarova,
  • Olga Sinitsyna,
  • Arkady Sinitsyn and
  • Valery Varlamov

17 January 2022

This study shows the research on the depolymerisation of insect and crab chitosans using novel enzymes. Enzyme preparations containing recombinant chitinase Chi 418 from Trichoderma harzianum, chitinase Chi 403, and chitosanase Chi 402 from Mycelioph...

  • Article
  • Open Access
12 Citations
4,224 Views
17 Pages

In Vitro Evaluation of the Cytotoxic Effect of Streptococcus pyogenes Strains, Protegrin PG-1, Cathelicidin LL-37, Nerve Growth Factor and Chemotherapy on the C6 Glioma Cell Line

  • Alexandr N. Chernov,
  • Anna Tsapieva,
  • Diana A. Alaverdian,
  • Tatiana A. Filatenkova,
  • Elvira S. Galimova,
  • Mariia Suvorova,
  • Olga V. Shamova and
  • Alexander N. Suvorov

17 January 2022

Brain cancer treatment, where glioblastoma represents up to 50% of all CNS malignancies, is one of the most challenging calls for neurooncologists. The major driver of this study was a search for new approaches for the treatment of glioblastoma. We t...

  • Review
  • Open Access
24 Citations
6,386 Views
18 Pages

Spatiotemporal Distribution and Analysis of Organophosphate Flame Retardants in the Environmental Systems: A Review

  • Sinozuko Hope Bika,
  • Abiodun Olagoke Adeniji,
  • Anthony Ifeanyi Okoh and
  • Omobola Oluranti Okoh

17 January 2022

In recent times, there has been a cumulative apprehension regarding organophosphate flame retardants (OPFRs) owing to their high manufacturing and usage after brominated flame retardants were strictly regulated and banned from being distributed and u...

  • Article
  • Open Access
11 Citations
4,917 Views
12 Pages

17 January 2022

DNA nanotechnology makes use of hydrophobically modified constructs to create synthetic membrane protein mimics. However, nucleic acid structures exhibit poor insertion efficiency, leading to a low activity of membrane-spanning DNA protein mimics. It...

  • Article
  • Open Access
32 Citations
5,988 Views
18 Pages

17 January 2022

Propolis is a natural bee product that is widely used in folk medicine. This study aimed to evaluate the antimicrobial and antibiofilm activities of ethanolic extract of propolis (EEP) on methicillin-resistant and sensitive Staphylococcus aureus (MRS...

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Molecules - ISSN 1420-3049