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Review

New-Onset Acute Kidney Disease Post COVID-19 Vaccination

by 1,†, 2,† and 1,*
1
Department of Nephrology, The Second Affiliated Hospital of Nanchang University, No. 1, Minde Road, Donghu District, Nanchang 330006, China
2
Department of Blood Transfusion, The Second Affiliated Hospital of Nanchang University, No. 1, Minde Road, Donghu District, Nanchang 330006, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editors: Ger Rijkers and Jean-Luc Murk
Vaccines 2022, 10(5), 742; https://doi.org/10.3390/vaccines10050742
Received: 13 April 2022 / Revised: 29 April 2022 / Accepted: 5 May 2022 / Published: 9 May 2022
(This article belongs to the Topic Global Analysis of SARS-CoV-2 Serology)
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an exceptional setback to the global economy and health. Vaccination is one of the most effective interventions to markedly decrease severe illness and death from COVID-19. In recent years, there have been increasingly more reports of new acute kidney injury (AKI) after COVID-19 vaccination. Podocyte injury, IgA nephropathy, vasculitis, tubulointerstitial injury, and thrombotic microangiopathy appear to be the main pathological phenotypes. Nonetheless, whether the link between the COVID-19 vaccine and acute kidney disease (AKD) is causal or coincidental remains to be verified. Here, we generalize some hypotheses for the emergence of AKD and its pathogenesis in response to certain COVID-19 vaccines. In fact, the enormous benefits of mass vaccination against COVID-19 in preventing COVID-19 morbidity and mortality cannot be denied. The purpose of this review is to assist in the clinical assessment and management of AKD following COVID-19 vaccination. View Full-Text
Keywords: acute kidney disease; acute kidney injury; COVID-19; SARS-CoV-2; vaccination acute kidney disease; acute kidney injury; COVID-19; SARS-CoV-2; vaccination
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MDPI and ACS Style

Li, Y.; Rao, M.; Xu, G. New-Onset Acute Kidney Disease Post COVID-19 Vaccination. Vaccines 2022, 10, 742. https://doi.org/10.3390/vaccines10050742

AMA Style

Li Y, Rao M, Xu G. New-Onset Acute Kidney Disease Post COVID-19 Vaccination. Vaccines. 2022; 10(5):742. https://doi.org/10.3390/vaccines10050742

Chicago/Turabian Style

Li, Yebei, Meiying Rao, and Gaosi Xu. 2022. "New-Onset Acute Kidney Disease Post COVID-19 Vaccination" Vaccines 10, no. 5: 742. https://doi.org/10.3390/vaccines10050742

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