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8 Results Found

  • Article
  • Open Access
23 Citations
4,980 Views
14 Pages

Trichodermin Induces G0/G1 Cell Cycle Arrest by Inhibiting c-Myc in Ovarian Cancer Cells and Tumor Xenograft-Bearing Mice

  • Ying Gao,
  • Sarah L. Miles,
  • Piyali Dasgupta,
  • Gary O. Rankin and ,
  • Stephen Cutler and
  • Yi Charlie Chen
  • + 1 author+ 0 author

Ovarian cancer is a fatal gynecological cancer because of a lack of early diagnosis, which often relapses as chemoresistant. Trichodermin, a trichothecene first isolated from Trichoderma viride, is an inhibitor of eukaryotic protein synthesis. Howeve...

(This article belongs to the Special Issue Natural Compounds with Cancer-Selective Toxicity)
  • Article
  • Open Access
18 Citations
5,728 Views
14 Pages

Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities

  • Javier E. Barúa,
  • Mercedes de la Cruz,
  • Nuria de Pedro,
  • Bastien Cautain and ,
  • Rosa Hermosa,
  • Rosa E. Cardoza,
  • Santiago Gutiérrez,
  • Enrique Monte,
  • Francisca Vicente and
  • Isidro G. Collado
  • + 5 authors+ 0 author

22 October 2019

Trichothecene mycotoxins are recognized as highly bioactive compounds that can be used in the design of new useful bioactive molecules. In Trichoderma brevicompactum, the first specific step in trichothecene biosynthesis is carried out by a terpene c...

(This article belongs to the Section Bioorganic Chemistry)
  • Article
  • Open Access
46 Citations
10,433 Views
13 Pages

Overexpression of the Trichoderma brevicompactum tri5 Gene: Effect on the Expression of the Trichodermin Biosynthetic Genes and on Tomato Seedlings

  • Anamariela Tijerino,
  • Rosa Hermosa,
  • Rosa E. Cardoza,
  • Javier Moraga and ,
  • Monica G. Malmierca,
  • Josefina Aleu,
  • Isidro G. Collado,
  • Enrique Monte and
  • Santiago Gutierrez
  • + 4 authors+ 0 author

23 September 2011

Trichoderma brevicompactum IBT 40841 produces trichodermin, a trichothecene-type toxin that shares most of the steps of its biosynthesis with harzianum A, another trichothecene produced by several Trichoderma species. The first specific step in the t...

(This article belongs to the Special Issue Trichothecenes)
  • Article
  • Open Access
2 Citations
3,164 Views
18 Pages

Inhibitory Effect and Mechanism of Trichoderma taxi and Its Metabolite on Trichophyton mentagrophyte

  • Chenwen Xiao,
  • Lin Li,
  • Yan Liu,
  • Yee Huang and ,
  • Yanli Wang,
  • Jiaoyu Wang,
  • Guolian Bao,
  • Guochang Sun and
  • Fucheng Lin
  • + 4 authors+ 0 author

25 September 2022

Trichophyton mentagrophytes is an important zoonotic dermatophyte, which seriously harms the skin of humans and animals. Chemical drugs are generally used for the prevention and treatment of the disease caused by T. mentagrophytes. Discovering new co...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,618 Views
15 Pages

Spores of Trichoderma Strains over P. vulgaris Beans: Direct Effect on Insect Attacks and Indirect Effect on Agronomic Parameters

  • Álvaro Rodríguez-González,
  • Guzmán Carro-Huerga,
  • Marcos Guerra,
  • Sara Mayo-Prieto and ,
  • Alejandra Juana Porteous-Álvarez,
  • Alicia Lorenzana,
  • María Piedad Campelo,
  • Alexia Fernández-Marcos,
  • Pedro Antonio Casquero and
  • Santiago Gutiérrez
  • + 5 authors+ 0 author

25 November 2022

Acanthoscelides obtectus is an insect pest that attacks wild and cultivated common beans (Phaseolus vulgaris L). Four Trichoderma strains, the T. arundinaceum IBT 40837 wild-type strain (=Ta37), a producer of trichothecene harzianum A (HA), two trans...

(This article belongs to the Section Insect Behavior and Pathology)
  • Article
  • Open Access
24 Citations
4,916 Views
13 Pages

18 March 2021

Cordyceps fumosorosea, an insect pathogenic fungus, produces different toxins/secondary metabolites which can act as pest control agents. This study reports the extraction and characterization of crude mycelial extracts of C. fumosorosea isolate SP50...

(This article belongs to the Section Mycotoxins)
  • Review
  • Open Access
26 Citations
5,264 Views
16 Pages

5 August 2021

The rational use of natural resources, including the creation of new and improvement of existing technologies in order to reduce the anthropogenic impact on the environment, is currently an important task. This review covers different methods of soft...

(This article belongs to the Section Wood Science and Forest Products)
  • Article
  • Open Access
7 Citations
3,583 Views
21 Pages

Germination and Agronomic Traits of Phaseolus vulgaris L. Beans Sprayed with Trichoderma Strains and Attacked by Acanthoscelides obtectus

  • Álvaro Rodríguez-González,
  • Marcos Guerra,
  • Daniela Ramírez-Lozano,
  • Pedro Antonio Casquero and
  • Santiago Gutiérrez

24 October 2021

Acanthoscelides obtectus, one of the world’s most important post-harvest pests, attacks wild and cultivated common beans (Phaseolus vulgaris L.). Four Trichoderma strains, Trichoderma arundinaceum IBT 40,837 (=Ta37), a wild-type strain producer of tr...

(This article belongs to the Special Issue Using Biological Control Agents in Crop Protection)