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26 Results Found

  • Communication
  • Open Access
31 Citations
4,689 Views
11 Pages

The Characterization of Arabidopsis mterf6 Mutants Reveals a New Role for mTERF6 in Tolerance to Abiotic Stress

  • Pedro Robles,
  • Sergio Navarro-Cartagena,
  • Almudena Ferrández-Ayela,
  • Eva Núñez-Delegido and
  • Víctor Quesada

Exposure of plants to abiotic stresses, such as salinity, cold, heat, or drought, affects their growth and development, and can significantly reduce their productivity. Plants have developed adaptive strategies to deal with situations of abiotic stre...

  • Article
  • Open Access
19 Citations
4,140 Views
19 Pages

Genome-Wide Identification and Characterization of the Mitochondrial Transcription Termination Factors (mTERFs) in Capsicum annuum L.

  • Bingqian Tang,
  • Lingling Xie,
  • Ting Yi,
  • Junheng Lv,
  • Huiping Yang,
  • Xiang Cheng,
  • Feng Liu and
  • Xuexiao Zou

31 December 2019

Mitochondrial transcription termination factors (mTERFs) regulate the expression of mitochondrial genes and are closely related to the function of the mitochondrion and chloroplast. In this study, the mTERF gene family in capsicum (Capsicum annuum L....

  • Article
  • Open Access
20 Citations
4,489 Views
25 Pages

3 February 2021

Plastid gene expression (PGE) is essential for chloroplast biogenesis and function and, hence, for plant development. However, many aspects of PGE remain obscure due to the complexity of the process. A hallmark of nuclear-organellar coordination of g...

  • Article
  • Open Access
350 Views
20 Pages

21 February 2026

Mitochondrial biogenesis requires coordinated expression from both nuclear and mitochondrial genomes. To understand the consequences of mitochondrial genome loss, we generated a mitochondrial DNA-depleted line (crm) in Chlamydomonas reinhardti...

  • Review
  • Open Access
28 Citations
4,912 Views
16 Pages

21 January 2021

Present-day chloroplast and mitochondrial genomes contain only a few dozen genes involved in ATP synthesis, photosynthesis, and gene expression. The proteins encoded by these genes are only a small fraction of the many hundreds of proteins that act i...

  • Article
  • Open Access
8 Citations
4,230 Views
12 Pages

2 February 2021

In plants, mTERF proteins are primarily found in mitochondria and chloroplasts. Studies have identified several mTERF proteins that affect plant development, respond to abiotic stresses, and regulate organellar gene expression, but the functions and...

  • Article
  • Open Access
8 Citations
2,488 Views
18 Pages

Analysis of the Tomato mTERF Gene Family and Study of the Stress Resistance Function of SLmTERF-13

  • Ao Su,
  • Siyu Ge,
  • Boyan Zhou,
  • Ziyu Wang,
  • Liping Zhou,
  • Ziwei Zhang,
  • Xiaoyu Yan,
  • Yu Wang,
  • Dalong Li and
  • Tingting Zhao
  • + 2 authors

3 August 2023

Mitochondrial transcription termination factor (mTERF) is a DNA-binding protein that is encoded by nuclear genes, ultimately functions in mitochondria and can affect gene expression. By combining with mitochondrial nucleic acids, mTERF regulates the...

  • Article
  • Open Access
1,140 Views
17 Pages

Genome-Wide Identification and Characterization of the mTERF Gene Family in Spinach and the Role of SomTERF5 in Response to Heat Stress

  • Ziyue Sun,
  • Li Li,
  • Yaqi Liu,
  • Yanshuang Liu,
  • Gaojian Li,
  • Yueyue Li,
  • Qingbo Yu,
  • Meihong Sun and
  • Xiaofeng Xu

22 May 2025

Spinach (Spinacia oleracea L.), a globally consumed, nutrient-dense vegetable, contains diverse vitamins and minerals. However, elevated temperatures can constrain yield by interrupting leaf development and photosynthetic efficiency. The mitochondria...

  • Article
  • Open Access
15 Citations
4,545 Views
19 Pages

Modulating p-AMPK/mTOR Pathway of Mitochondrial Dysfunction Caused by MTERF1 Abnormal Expression in Colorectal Cancer Cells

  • Qianqian Liu,
  • Longlong Zhang,
  • Yayan Zou,
  • Ying Tao,
  • Bing Wang,
  • Bin Li,
  • Ruai Liu,
  • Boyong Wang,
  • Lei Ding and
  • Min Yu
  • + 4 authors

15 October 2022

Human mitochondrial transcription termination factor 1 (MTERF1) has been demonstrated to play an important role in mitochondrial gene expression regulation. However, the molecular mechanism of MTERF1 in colorectal cancer (CRC) remains largely unknown...

  • Review
  • Open Access
37 Citations
7,546 Views
16 Pages

28 February 2019

Given their endosymbiotic origin, chloroplasts and mitochondria genomes harbor only between 100 and 200 genes that encode the proteins involved in organellar gene expression (OGE), photosynthesis, and the electron transport chain. However, as the act...

  • Article
  • Open Access
10 Citations
3,481 Views
16 Pages

Genomic Scan of Male Fertility Restoration Genes in a ‘Gülzow’ Type Hybrid Breeding System of Rye (Secale cereale L.)

  • Nikolaj Meisner Vendelbo,
  • Khalid Mahmood,
  • Pernille Sarup,
  • Peter Skov Kristensen,
  • Jihad Orabi and
  • Ahmed Jahoor

27 August 2021

Efficient and stable restoration of male fertility (Rf) is a prerequisite for large-scale hybrid seed production but remains an inherent issue in the predominant fertility control system of rye (Secale cereale L.). The ‘Gülzow’ (G)-type cytoplasmic m...

  • Article
  • Open Access
4 Citations
2,466 Views
13 Pages

13 January 2023

Mitochondria are responsible for energy generation, as well as key metabolic and signaling pathways, and thus affect the entire developmental process of plants as well as their responses to stress. In metazoans, mitochondrial transcription terminatio...

  • Article
  • Open Access
1,973 Views
9 Pages

Larches of Kuzhanovo Have a Unique Mutation in the atpF–atpH Intergenic Spacer

  • Alexander Artyukhin,
  • Yuliya Sharifyanova,
  • Mikhail M. Krivosheev and
  • Elena V. Mikhaylova

15 February 2023

The larches of Kuzhanovo (Larix sibirica Ledeb.) are protected trees with a round crown growing in the Southern Urals. In 2020 vandals sawed the sapwood of these trees, which exposed the problem of insufficient conservation measures. Their origin and...

  • Article
  • Open Access
5 Citations
2,556 Views
18 Pages

Phytohormones as Regulators of Mitochondrial Gene Expression in Arabidopsis thaliana

  • Ivan A. Bychkov,
  • Elena S. Pojidaeva,
  • Anastasia S. Doroshenko,
  • Vladimir A. Khripach,
  • Natalia V. Kudryakova and
  • Victor V. Kusnetsov

29 November 2023

The coordination of activities between nuclei and organelles in plant cells involves information exchange, in which phytohormones may play essential roles. Therefore, the dissection of the mechanisms of hormone-related integration between phytohormon...

  • Article
  • Open Access
19 Citations
8,562 Views
14 Pages

Transcriptome Profile of the Variegated Ficus microcarpa c.v. Milky Stripe Fig Leaf

  • Tin-Han Shih,
  • Szu-Hsien Lin,
  • Meng-Yuan Huang,
  • Wen-Dar Huang and
  • Chi-Ming Yang

Photosynthetic properties and transcriptomic profiles of green and white sectors of Ficus microcarpa (c.v. milky stripe fig) leaves were examined in naturally variegated plants. An anatomic analysis indicated that chloroplasts of the white sectors co...

  • Feature Paper
  • Article
  • Open Access
296 Views
16 Pages

Knockout of MDHAR Paralogs Suggests Broader Regulatory Roles Beyond Ascorbic Acid Recycling in Lettuce

  • Ugo Rogo,
  • Samuel Simoni,
  • Ambra Viviani,
  • Claudio Pugliesi,
  • Marco Fambrini,
  • Alberto Vangelisti,
  • Lucia Natali,
  • Andrea Cavallini,
  • Richard Michelmore and
  • Tommaso Giordani

Ascorbic acid (AsA) is a key antioxidant and nutrient in plants, regulating reactive oxygen species (ROS) levels and maintaining cellular redox homeostasis. The AsA recycling pathway sustains AsA pools by restoring its oxidized forms, ensuring intrac...

  • Article
  • Open Access
4 Citations
2,715 Views
17 Pages

3 September 2020

Polyploidization is a universal phenomenon in plants and plays a crucial role in evolution. In this study, the transcriptomes of developing seeds of a synthetic Brassica hexaploid and its parents (B. rapa and B. carinata) were analyzed to find the ge...

  • Article
  • Open Access
27 Citations
4,998 Views
17 Pages

Genome-Wide Association Study Reveals Marker–Trait Associations for Early Vegetative Stage Salinity Tolerance in Rice

  • Ashutosh Kumar Yadav,
  • Aruna Kumar,
  • Nitasha Grover,
  • Ranjith Kumar Ellur,
  • Haritha Bollinedi,
  • Subbaiyan Gopala Krishnan,
  • Prolay Kumar Bhowmick,
  • Kunnummal Kurungara Vinod,
  • Mariappan Nagarajan and
  • Ashok Kumar Singh

16 March 2021

Rice germplasm is a rich resource for discovering genes associated with salt tolerance. In the current study, a set of 96 accessions were evaluated for seedling stage salinity tolerance and its component traits. Significant phenotypic variation was o...

  • Article
  • Open Access
1,424 Views
18 Pages

Light plays a crucial role in anthocyanin biosynthesis and color development in plants. Anthocyanins found in Lycium ruthenicum Murray are crucial for the plant’s defense against UV light and environmental stress, as well as for their economic...

  • Article
  • Open Access
10 Citations
3,475 Views
16 Pages

Influences of Long-Term Exercise and High-Fat Diet on Age-Related Telomere Shortening in Rats

  • Maria Donatella Semeraro,
  • Gunter Almer,
  • Wilfried Renner,
  • Hans-Jürgen Gruber and
  • Markus Herrmann

10 May 2022

(1) Obesity and exercise are believed to modify age-related telomere shortening by regulating telomerase and shelterins. Existing studies are inconsistent and limited to peripheral blood mononuclear cells (PBMCs) and selected solid tissues. (2) Femal...

  • Article
  • Open Access
8 Citations
4,004 Views
19 Pages

Morpho-Physiological, Biochemical, and Genetic Responses to Salinity in Medicago truncatula

  • Sabrine Hdira,
  • Loua Haddoudi,
  • Mohsen Hanana,
  • Irene Romero,
  • Asma Mahjoub,
  • Hatem Ben Jouira,
  • Ndiko Ludidi,
  • Maria Teresa Sanchez-Ballesta,
  • Chedly Abdelly and
  • Mounawer Badri

20 April 2021

We used an integrated morpho-physiological, biochemical, and genetic approach to investigate the salt responses of four lines (TN1.11, TN6.18, JA17, and A10) of Medicago truncatula. Results showed that TN1.11 exhibited a high tolerance to salinity, c...

  • Article
  • Open Access
7 Citations
2,522 Views
16 Pages

Inflammaging: Expansion of Molecular Phenotype and Role in Age-Associated Female Infertility

  • Dmitry Ivanov,
  • Anna Drobintseva,
  • Valeriia Rodichkina,
  • Ekaterina Mironova,
  • Tatyana Zubareva,
  • Yuliya Krylova,
  • Svetlana Morozkina,
  • Maria Greta Pia Marasco,
  • Gianluigi Mazzoccoli and
  • Igor Kvetnoy
  • + 1 author

Cellular aging is considered as one of the main factors implicated in female infertility. We evaluated the expression of senescence-associated secretory phenotype (SASP) markers and additional molecular factors in an in vitro model of cellular aging....

  • Article
  • Open Access
5 Citations
2,820 Views
23 Pages

Constructing and Evaluating a Mitophagy-Related Gene Prognostic Model: Implications for Immune Landscape and Tumor Biology in Lung Adenocarcinoma

  • Jin Wang,
  • Kaifan Liu,
  • Jiawen Li,
  • Hailong Zhang,
  • Xian Gong,
  • Xiangrong Song,
  • Meidan Wei,
  • Yaoyu Hu and
  • Jianxiang Li

16 February 2024

Mitophagy, a conserved cellular mechanism, is crucial for cellular homeostasis through the selective clearance of impaired mitochondria. Its emerging role in cancer development has sparked interest, particularly in lung adenocarcinoma (LUAD). Our stu...

  • Article
  • Open Access
1,396 Views
14 Pages

C-Terminal Extended Domain-Independent Telomere Maintenance: Modeling the Function of TIN2 Isoforms in Mus musculus

  • Chiao-Ming Huang,
  • Yi-Ling Shen,
  • Chia-Lo Ho,
  • Tzeng-Erh Chen,
  • Hsuan-Yu Hsia,
  • Zhou Songyang and
  • Liuh-Yow Chen

TIN2 (TERF1 interacting nuclear factor 2) is a telomeric shelterin complex component, essential for telomere protection and early embryonic development in mammals. In humans, TIN2 isoforms arise from alternative splicing, but their specific roles in...

  • Article
  • Open Access
11 Citations
3,697 Views
15 Pages

Impact of Maternal Mediterranean-Type Diet Adherence on Microbiota Composition and Epigenetic Programming of Offspring

  • Tamlyn Sasaki,
  • Megan Kawamura,
  • Chirstyn Okuno,
  • Kayleen Lau,
  • Jonathan Riel,
  • Men-Jean Lee and
  • Corrie Miller

22 December 2023

Understanding how maternal diet affects in utero neonatal gut microbiota and epigenetic regulation may provide insight into disease origins and long-term health. The impact of Mediterranean diet pattern adherence (MDA) on fetal gut microbiome and epi...

  • Article
  • Open Access
52 Citations
6,626 Views
26 Pages

7 April 2021

Rice is an important grain that is the staple food for most of the world’s population. Drought is one of the major stresses that negatively affects rice yield. The nature of drought tolerance in rice is complex as it is determined by various componen...