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35 Results Found

  • Article
  • Open Access
40 Citations
3,094 Views
8 Pages

Prognostic Value of Systemic Immune-Inflammation Index for Major Adverse Cardiac Events and Mortality in Severe Aortic Stenosis Patients after TAVI

  • Aydin Rodi Tosu,
  • Muhsin Kalyoncuoglu,
  • Halil İbrahim Biter,
  • Sinem Cakal,
  • Murat Selcuk,
  • Tufan Çinar,
  • Erdal Belen and
  • Mehmet Mustafa Can

Background and objectives: In this study, we aimed to evaluate whether the systemic immune-inflammation index (SII) has a prognostic value for major adverse cardiac events (MACEs), including stroke, re-hospitalization, and short-term all-cause mortal...

  • Article
  • Open Access
968 Views
12 Pages

Redo-Transcatheter Aortic Valve Implantation (Redo-TAVI)—Pilot Study from Multicentre Nationwide Registry

  • Szymon Jonik,
  • Maciej Mazurek,
  • Bartosz Rymuza,
  • Jan Jankowski,
  • Maciej Dąbrowski,
  • Rafał Wolny,
  • Piotr Chodór,
  • Krzysztof Wilczek,
  • Wojciech Fil and
  • Zenon Huczek
  • + 12 authors

14 November 2025

Objectives: The aim of this study is to evaluate the safety and efficacy of repeat transcatheter aortic valve implantation (redo-TAVI) in the polish population. Methods: In this multicentre nationwide registry (ClinicalTrials.gov identifier, NCT03361...

  • Article
  • Open Access
14 Citations
2,726 Views
10 Pages

Multidimensional Prognostic Index and Outcomes in Older Patients Undergoing Transcatheter Aortic Valve Implantation: Survival of the Fittest

  • Jeannette A. Goudzwaard,
  • Sadhna Chotkan,
  • Marjo J. A. G. De Ronde-Tillmans,
  • Mattie J. Lenzen,
  • Maarten P. H. van Wiechen,
  • Joris F. W. Ooms,
  • Harmke A. Polinder-Bos,
  • Madelon de Beer-Leentfaar,
  • Nicolas M. Van Mieghem and
  • Francesco U. S. Mattace-Raso
  • + 3 authors

11 August 2021

Selecting patients with a high chance of endured benefit from transcatheter aortic valve implantation (TAVI) is becoming relevant with changing indications and increasing number of TAVI being performed. The aim of our study was to investigate the ass...

  • Article
  • Open Access
1 Citations
1,009 Views
23 Pages

The Impact of Periprocedural Prosthetic Valve Leak After Transcatheter Aortic Valve Implantation

  • Shafaqat Ali,
  • Sanchit Duhan,
  • Thannon Alsaeed,
  • Lalitsiri Atti,
  • Faryal Farooq,
  • Bijeta Keisham,
  • Ryan Berry,
  • Yasar Sattar,
  • Ahmad Munir and
  • James Robert Brašić
  • + 3 authors

A periprocedural prosthetic valve leak (PVL) after transcatheter aortic valve implantation (TAVI), a minimally invasive treatment modality for patients with severe, symptomatic aortic stenosis, may entail serious morbidity. Cohorts hospitalized for T...

  • Article
  • Open Access
1 Citations
2,391 Views
8 Pages

Improvement in Vascular Endothelial Function following Transcatheter Aortic Valve Implantation

  • Shuhei Tanaka,
  • Teruhiko Imamura,
  • Ryuichi Ushijima,
  • Mitsuo Sobajima,
  • Nobuyuki Fukuda,
  • Hiroshi Ueno,
  • Tadakazu Hirai and
  • Koichiro Kinugawa

24 September 2021

Background and objectives: Endothelial dysfunction is associated with exercise intolerance and adverse cardiovascular events. Transcatheter aortic valve implantation (TAVI) is applied to treat elderly patients with severe aortic stenosis, but less is...

  • Article
  • Open Access
31 Citations
4,839 Views
19 Pages

Long-Term Prognosis Value of Paravalvular Leak and Patient–Prosthesis Mismatch following Transcatheter Aortic Valve Implantation: Insight from the France-TAVI Registry

  • Pierre Deharo,
  • Lionel Leroux,
  • Alexis Theron,
  • Jérome Ferrara,
  • Antoine Vaillier,
  • Nicolas Jaussaud,
  • Alizée Porto,
  • Pierre Morera,
  • Vlad Gariboldi and
  • Thomas Cuisset
  • + 17 authors

17 October 2022

Background: Transcatheter aortic valve implantation (TAVI) is the preferred treatment for symptomatic severe aortic stenosis (AS) in a majority of patients across all surgical risks. Patients and methods: Paravalvular leak (PVL) and patient–pro...

  • Article
  • Open Access
2 Citations
1,335 Views
12 Pages

Beyond the Obesity Paradox: Analysis of New Prognostic Factors in Transcatheter Aortic Valve Implantation Procedure

  • Francesca Ricci,
  • Leonardo Benelli,
  • Monia Pasqualetto,
  • Mario Laudazi,
  • Luca Pugliese,
  • Maria Volpe,
  • Cecilia Cerimele,
  • Carlo Di Donna,
  • Francesco Garaci and
  • Marcello Chiocchi

Scope: The main purpose of our study was to collect computed tomography (CT) measurements of fat parameters that are significantly related to body mass index (BMI) and evaluate the associations of these measurements and sarcopenia with early and long...

  • Article
  • Open Access
1,451 Views
19 Pages

Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model?

  • Maksym Jura,
  • Stanisław Tubek,
  • Jędrzej Reczuch,
  • Rafał Seredyński,
  • Piotr Niewiński,
  • Marcin Protasiewicz,
  • Beata Ponikowska and
  • Bartłomiej Paleczny

Background: A reduction in carotid artery blood flow (CABF) and ultimately in wall shear stress (WSS) is a major driver of heightened peripheral chemoreceptor (PCh) activity in animal models of heart failure. However, it is yet to be translated to hu...

  • Article
  • Open Access
1 Citations
2,632 Views
9 Pages

6 April 2020

Background and objectives: Plasma arginine vasopressin (P-AVP) is regulated by the non-osmotic pathway in patients with heart failure (HF) and reduced ejection fraction. However, the regulation of P-AVP in patients with severe aortic stenosis (AS) re...

  • Article
  • Open Access
1,446 Views
12 Pages

Short-Term Changes in Arterial Stiffness Measured by 2D Speckle Tracking in Patients Undergoing Transcatheter Aortic Valve Implantation

  • Leonie Arnold,
  • Nikolaus Alexander Haas,
  • André Jakob,
  • Julius Fischer,
  • Steffen Massberg,
  • Simon Deseive and
  • Felix Sebastian Oberhoffer

30 December 2023

Arterial stiffness has received increasing interest as a cardiovascular marker in patients with aortic valve stenosis (AS). So far, studies on the impact of aortic valve replacement (AVR) on arterial stiffness have been equivocal. Two-dimensional spe...

  • Article
  • Open Access
26 Citations
3,090 Views
10 Pages

Non-Invasive Myocardial Work in Patients with Severe Aortic Stenosis

  • Salvatore De Rosa,
  • Jolanda Sabatino,
  • Antonio Strangio,
  • Isabella Leo,
  • Letizia Rosa Romano,
  • Carmen Anna Spaccarotella,
  • Annalisa Mongiardo,
  • Alberto Polimeni,
  • Sabato Sorrentino and
  • Ciro Indolfi

29 January 2022

Changes in cardiac mechanics after correction of severe Aortic Stenosis (AS) are under-investigated. Myocardial Work (MW) is emerging as a useful non-invasive correlate of invasively measured myocardial performance and oxygen consumption. The aim of...

  • Article
  • Open Access
2 Citations
2,098 Views
13 Pages

One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population

  • Po-Han Lin,
  • Hao-Ji Wei,
  • Shih-Rong Hsieh,
  • Hung-Wen Tsai,
  • Chu-Leng Yu,
  • Wen-Lieng Lee and
  • Yung-Szu Wu

12 May 2023

Background: The aim of our study was to provide real-world data on outcomes for elderly Taiwanese patients who underwent transcatheter aortic valve replacement or surgical aortic valve replacement in different risk groups. Methods: From March 2011 th...

  • Article
  • Open Access
1,141 Views
13 Pages

Background: Transcatheter aortic valve implantation (TAVI) is increasingly used in elderly patients with severe aortic stenosis, yet data on nonagenarians remain limited. This study aimed to compare clinical characteristics and outcomes of patients a...

  • Article
  • Open Access
583 Views
12 Pages

Hemoglobin-Geriatric Nutritional Risk Index Predicts Major Adverse Cardiovascular Events After Transcatheter Aortic Valve Implantation

  • Takeshi Sasaki,
  • Takahiro Miura,
  • Harutoshi Tamura,
  • Yuya Takakubo,
  • Michiaki Takagi and
  • Satoru Ebihara

30 October 2025

Background/Objectives: Numerous older patients undergo transcatheter valve implantation (TAVI) and frequently experience preoperative malnutrition and anemia, which markedly influence postoperative outcomes. This study investigated whether the Hemogl...

  • Article
  • Open Access
885 Views
15 Pages

The Prognostic Value of Tricuspid Annular Dimensions in TAVI Patients: A CT-Based Retrospective Analysis of Risk Stratification and Long-Term Outcomes

  • Nikolaos Schörghofer,
  • Christoph Knapitsch,
  • Gretha Hecke,
  • Nikolaus Clodi,
  • Lucas Brandstetter,
  • Matthias Hammerer,
  • Klaus Hergan,
  • Uta C. Hoppe,
  • Elke Boxhammer and
  • Bernhard Scharinger

Background: Transcatheter aortic valve implantation (TAVI) has transformed the treatment of severe aortic stenosis (AS), particularly in high-risk patients. However, comorbidities such as pulmonary hypertension (PH) and secondary tricuspid regurgitat...

  • Article
  • Open Access
8 Citations
2,959 Views
9 Pages

Sleep Quality in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)

  • Giulia Lorenzoni,
  • Danila Azzolina,
  • Chiara Fraccaro,
  • Caterina Zoccarato,
  • Clara Minto,
  • Sabino Iliceto,
  • Dario Gregori and
  • Giuseppe Tarantini

The present study aimed to analyze sleep quality and quality of Life (QoL) in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). It was conducted at the Interventional Cardiology Unit of the Department of Cardiac, Thoracic, Vascular...

  • Article
  • Open Access
1,085 Views
13 Pages

Non-Invasive Hemodynamic Monitoring in Transcatheter Aortic Valve Implantation

  • Thorald Stolte,
  • Janarthanan Sathananthan,
  • Jakob Johannes Reichl,
  • Jasper Boeddinghaus,
  • Max Wagener,
  • Christian Schöpflin,
  • Christoph Kaiser,
  • Gregor Leibundgut,
  • Felix Mahfoud and
  • Thomas Nestelberger
  • + 2 authors

28 May 2025

Background/Objectives: Aortic valve stenosis (AS) is a prevalent cardiovascular condition among elderly patients frequently treated with Transcatheter Aortic Valve Implantation (TAVI). Traditional hemodynamic monitoring during TAVI relies on invasive...

  • Article
  • Open Access
311 Views
16 Pages

Validation of the VALVEX Questionnaire for Assessing Patient Experience During the Transcatheter Aortic Valve Implantation Process

  • Miryam González-Cebrian,
  • Elena Calvo,
  • Sara Alonso Meléndez,
  • Héctor Gómez García,
  • Francisco Javier Rubio Gil,
  • Ignacio Cruz-González,
  • Pedro L. Sánchez,
  • Luis Miguel Rincón and
  • José Luis Mendoza-García

2 December 2025

Background and Objectives: Degenerative aortic stenosis has become the most common primary valve lesion referred for intervention, with thousands of transcatheter aortic valve implantation (TAVI) procedures being performed annually. To date, there ar...

  • Systematic Review
  • Open Access
1,985 Views
23 Pages

Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation—A Systematic Review

  • Natalia Świątoniowska-Lonc,
  • Filip Klausa,
  • Krzysztof Ściborski,
  • Agnieszka Wysokińska-Kordybach,
  • Waldemar Banasiak and
  • Adrian Doroszko

20 February 2025

Backround/Objectives: Aortic stenosis (AS) is the most commonly acquired valvular disorder. Patient risk stratification and the development of an accurate and reliable tool are crucial in identifying suitable candidates for TAVI. The present review s...

  • Article
  • Open Access
16 Citations
3,111 Views
18 Pages

Optimal Oversizing Index Depending on Valve Type and Leakage-Proof Function for Preventing Paravalvular Leakage after Transcatheter Aortic Valve Implantation

  • You-Jeong Ki,
  • Jeehoon Kang,
  • Hak Seung Lee,
  • Mineok Chang,
  • Jung-Kyu Han,
  • Han-Mo Yang,
  • Kyung Woo Park,
  • Hyun-Jae Kang,
  • Bon-Kwon Koo and
  • Hyo-Soo Kim

4 December 2020

Paravalvular leak (PVL) is an important complication of transcatheter aortic valve implantation (TAVI) and is associated with poor prognosis. We aimed to identify the risk factors for PVL after TAVI including patient (calcium amount or location), dev...

  • Article
  • Open Access
3 Citations
1,747 Views
24 Pages

Hemodynamics of Proximal Coronary Lesions in Patients Undergoing Transcatheter Aortic Valve Implantation: Patient-Specific In Silico Study

  • Yahia Bellouche,
  • Sirine Abdelli,
  • Sinda Hannachi,
  • Clement Benic,
  • Florent Le Ven and
  • Romain Didier

Aortic stenosis (AS) frequently coexists with coronary artery disease (CAD), complicating revascularization decisions. The use of coronary physiology indices, such as the fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), and coronar...

  • Article
  • Open Access
7 Citations
2,994 Views
14 Pages

Predictors of Conduction Disturbances Requiring New Permanent Pacemaker Implantation following Transcatheter Aortic Valve Implantation Using the Evolut Series

  • Mahmoud Abdelshafy,
  • Ahmed Elkoumy,
  • Hesham Elzomor,
  • Mohammad Abdelghani,
  • Ruth Campbell,
  • Ciara Kennedy,
  • William Kenny Gibson,
  • Simone Fezzi,
  • Philip Nolan and
  • Osama Soliman
  • + 8 authors

22 July 2023

(1) Background: Conduction disturbance requiring a new permanent pacemaker (PPM) after transcatheter aortic valve implantation (TAVI) has traditionally been a common complication. New implantation techniques with self-expanding platforms have reporte...

  • Article
  • Open Access
1 Citations
1,253 Views
11 Pages

15 January 2025

Background: Myocardial work (MW) is a new echocardiographic parameter used in the assessment of cardiac energy expenditure. The aim of the current study was to evaluate changes in left ventricular MW parameters in patients with severe aortic stenosis...

  • Systematic Review
  • Open Access
655 Views
17 Pages

Effect of Transcatheter Aortic Valve Implantation on Non-Invasive Myocardial Work Parameters: A Systematic Review and Meta-Analysis

  • Isabella Leo,
  • Federico Sicilia,
  • Jolanda Sabatino,
  • Angelica Cersosimo,
  • Nicole Carabetta,
  • Antonio Strangio,
  • Giuseppe Panuccio,
  • Giovanni Canino,
  • Jessica Ielapi and
  • Salvatore De Rosa
  • + 3 authors

2 October 2025

Background/Objectives: Aortic stenosis (AS) leads to progressive left ventricular (LV) pressure overload, adverse myocardial remodeling, and eventual functional decline. While traditional parameters such as left ventricular ejection fraction (LVEF) m...

  • Article
  • Open Access
633 Views
11 Pages

Advanced Haemodynamic Monitoring During Transfemoral Aortic Valve Replacement: A Prospective Pilot Study

  • Astrid Bergmann,
  • Philip Woldt,
  • Lena Steins,
  • Nikolai Hulde,
  • Janis Fliegenschmidt,
  • Cornelia Piper,
  • Tanja Rudolph and
  • Vera von Dossow

5 November 2025

This pilot study aims to compare advanced and standard haemodynamic monitoring during TAVI in terms of predicting and avoiding hypotension. Intraoperative hypotension influences postoperative outcomes by increasing mortality, renal failure, and cardi...

  • Article
  • Open Access
10 Citations
2,021 Views
17 Pages

Long-Term Outcomes of Aortic Stenosis Patients with Different Flow/Gradient Patterns Undergoing Transcatheter Aortic Valve Implantation

  • George Oikonomou,
  • Anastasios Apostolos,
  • Maria Drakopoulou,
  • Chryssavgi Simopoulou,
  • Maria Karmpalioti,
  • Pantelis Toskas,
  • Konstantinos Stathogiannis,
  • Maria Xanthopoulou,
  • Nikolaos Ktenopoulos and
  • Konstantinos Toutouzas
  • + 3 authors

20 February 2024

Background: Few data exist on the comparative long-term outcomes of severe aortic stenosis (AS) patients with different flow-gradient patterns undergoing transcatheter aortic valve implantation (TAVI). This study sought to evaluate the impact of the...

  • Study Protocol
  • Open Access
1 Citations
2,173 Views
9 Pages

The prevalence of coronary artery disease (CAD) in patients with severe aortic stenosis (AS) is 30–68%. Nevertheless, there is still not enough evidence to use invasive assessment of lesion severity, because the hemodynamic milieu of AS may imp...

  • Article
  • Open Access
3,020 Views
11 Pages

Prognostic Impact of the Get-with-the-Guidelines Heart-Failure Risk Score (GWTG-HF) after Transcatheter Aortic Valve Replacement in Patients with Low-Flow–Low-Gradient Aortic Valve Stenosis

  • Clemens Eckel,
  • Johannes Blumenstein,
  • Oliver Husser,
  • Dagmar Sötemann,
  • Christina Grothusen,
  • Judith Schlüter,
  • Marc Becher,
  • Holger Nef,
  • Albrecht Elsässer and
  • Vedat Tiyerili
  • + 2 authors

Objectives: This study examined the prognostic value of the get-with-the-guidelines heart-failure risk score (GWTG-HF) on mortality in patients with low-flow–low-gradient aortic valve stenosis (LFLG-AS) after transcatheter aortic valve implanta...

  • Article
  • Open Access
5 Citations
2,098 Views
10 Pages

Elevated Fasting Glucose and C-Reactive Protein Levels Predict Increased All-Cause Mortality after Elective Transcatheter Aortic Valve Implantation

  • Gabor Dekany,
  • Katalin Keresztes,
  • Vince P. Bartos,
  • Orsolya Csenteri,
  • Sara Gharehdaghi,
  • Gergely Horvath,
  • Abdelkrim Ahres,
  • Christian M. Heesch,
  • Tunde Pinter and
  • Peter Andreka
  • + 2 authors

24 December 2022

Surgical aortic valve replacement in the elderly is now being supplanted by transcatheter aortic valve implantation (TAVI). Scoring systems to predict survival after catheter-based procedures are understudied. Both diabetes (DM) and underlying inflam...

  • Article
  • Open Access
410 Views
19 Pages

Osaka Prognostic Score Predicts In-Hospital and One-Year Mortality Following Transcatheter Aortic Valve Implantation

  • Murat Akdoğan,
  • Emine Cansu Yücel,
  • Alperen Taş,
  • Yusuf Bozkurt Şahin,
  • Çağatay Tunca,
  • Ahmet Kıvrak,
  • Kürşat Akbuğa,
  • Veysel Ozan Tanık,
  • Ali Sezgin and
  • Bülent Özlek

30 November 2025

Background and Objectives: Conventional risk models may not adequately capture key biological determinants of mortality following transcatheter aortic valve implantation (TAVI), such as inflammation, malnutrition, and immune dysfunction. The Osaka Pr...

  • Article
  • Open Access
1 Citations
1,753 Views
10 Pages

Combining Minimally Invasive Direct Coronary Artery Bypass Grafting with Transapical Aortic Valve Implantation—The Next Level Heart Team Approach

  • Jules Miazza,
  • Ion Vasiloi,
  • Luca Koechlin,
  • Brigitta Gahl,
  • David Santer,
  • Denis Berdajs,
  • Thomas Nestelberger,
  • Christoph Kaiser,
  • Friedrich Eckstein and
  • Oliver Reuthebuch

1 November 2023

We present the results of a combined approach for transapical aortic valve replacement and minimally invasive coronary artery bypass grafting (taTAVI-MIDCAB) in patients with combined aortic stenosis and coronary artery disease. Background: For patie...

  • Article
  • Open Access
5 Citations
2,083 Views
15 Pages

Feasibility of Reduced Iodine Loads for Vascular Assessment Prior to Transcatheter Aortic Valve Implantation (TAVI) Using Spectral Detector CT

  • Christopher Schuppert,
  • Janek Salatzki,
  • Florian André,
  • Johannes Riffel,
  • David L. Mangold,
  • Claudius Melzig,
  • Muhammad Taha Hagar,
  • Hans-Ulrich Kauczor,
  • Tim F. Weber and
  • Thuy D. Do
  • + 1 author

Reduced iodine loads for computed tomography (CT)-based vascular assessment prior to transcatheter aortic valve implantation (TAVI) may be feasible in conjunction with a spectral detector CT scanner. This prospective single-center study considered 10...

  • Article
  • Open Access
2 Citations
2,754 Views
12 Pages

Core Lab Adjudication of the ACURATE neo2 Hemodynamic Performance Using Computed-Tomography-Corrected Left Ventricular Outflow Tract Area

  • Ahmed Elkoumy,
  • Andreas Rück,
  • Won-Keun Kim,
  • Mohamed Abdel-Wahab,
  • Mahmoud Abdelshafy,
  • Ole De Backer,
  • Hesham Elzomor,
  • Christian Hengstenberg,
  • Sameh K. Mohamed and
  • Osama Soliman
  • + 5 authors

17 October 2022

(1) Background: Hemodynamic assessment of prosthetic heart valves using conventional 2D transthoracic Echocardiography-Doppler (2D-TTE) has limitations. Of those, left ventricular outflow tract (LVOT) area measurement is one of the major limitations...

  • Article
  • Open Access
5 Citations
2,445 Views
20 Pages

Single-Center Experience with the Balloon-Expandable Myval Transcatheter Aortic Valve System in Patients with Bicuspid Anatomy: Procedural and 30-Day Follow-Up

  • Balázs Magyari,
  • Bálint Kittka,
  • Ilona Goják,
  • Kristóf Schönfeld,
  • László Botond Szapáry,
  • Mihály Simon,
  • Rudolf Kiss,
  • Andrea Bertalan,
  • Edit Várady and
  • Iván Gábor Horváth
  • + 2 authors

17 January 2024

Aims: To report our single-center data regarding the initial 52 consecutive patients with a bicuspid aortic valve who underwent a Transcatheter Aortic Valve Implantation (TAVI) procedure using the new balloon-expandable MYVAL system. The focus is on...

  • Article
  • Open Access
2 Citations
2,376 Views
14 Pages

Reducing Left Ventricular Wall Stress through Aortic Valve Enlargement via Transcatheter Aortic Valve Implantation in Severe Aortic Stenosis

  • Chih-Yao Chiang,
  • Shen-Che Lin,
  • Jung-Cheng Hsu,
  • Jer-Shen Chen,
  • Jih-Hsin Huang and
  • Kuan-Ming Chiu

27 June 2024

Background: In aortic stenosis, the left ventricle exerts additional force to pump blood through the narrowed aortic valve into the downstream arterial vasculature. Adaptive hypertrophy helps to maintain wall stress homeostasis but at the expense of...