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19 Results Found

  • Article
  • Open Access
13 Citations
4,378 Views
16 Pages

Assimilation of Cholesterol by Monascus purpureus

  • Theresa P. T. Nguyen,
  • Margaret A. Garrahan,
  • Sabrina A. Nance,
  • Catherine E. Seeger and
  • Christian Wong

9 December 2020

Monascus purpureus, a filamentous fungus known for its fermentation of red yeast rice, produces the metabolite monacolin K used in statin drugs to inhibit cholesterol biosynthesis. In this study, we show that active cultures of M. purpureus CBS 109.0...

  • Article
  • Open Access
30 Citations
4,977 Views
17 Pages

Strain-Specific Effects of Bifidobacterium longum on Hypercholesterolemic Rats and Potential Mechanisms

  • Jinchi Jiang,
  • Caie Wu,
  • Chengcheng Zhang,
  • Qingsong Zhang,
  • Leilei Yu,
  • Jianxin Zhao,
  • Hao Zhang,
  • Arjan Narbad,
  • Wei Chen and
  • Qixiao Zhai

28 January 2021

Hypercholesterolemia is an independent risk factor of cardiovascular disease, which is among the major causes of death worldwide. The aim of this study was to explore whether Bifidobacterium longum strains exerted intra-species differences in cholest...

  • Article
  • Open Access
33 Citations
4,456 Views
18 Pages

Potential Probiotic Strains of Saccharomyces and Non-Saccharomyces: Functional and Biotechnological Characteristics

  • Pilar Fernández-Pacheco,
  • Cristina Pintado,
  • Ana Briones Pérez and
  • María Arévalo-Villena

2 March 2021

Due to the evident demand for probiotic microorganisms, a growing number of scientific studies have involved the preliminary selection of new strains, but deeper studies for knowing specific functional and biotechnological properties are needed. In t...

  • Article
  • Open Access
11 Citations
3,898 Views
20 Pages

Evaluating the Probiotic Potential of Lactic Acid Bacteria Implicated in Natural Fermentation of Table Olives, cv. Cobrançosa

  • Joana Coimbra-Gomes,
  • Patrícia J. M. Reis,
  • Tânia G. Tavares,
  • Miguel A. Faria,
  • F. Xavier Malcata and
  • Angela C. Macedo

The probiotic features of Lactiplantibacillus (L.) pentosus and L. paraplantarum strains, endogenous in Cobrançosa table olives from northeast Portugal, were assessed in terms of functional properties and health benefits. Fourteen lactic acid...

  • Review
  • Open Access
49 Citations
11,729 Views
21 Pages

The Role of Bifidobacteria in Predictive and Preventive Medicine: A Focus on Eczema and Hypercholesterolemia

  • Luisa Marras,
  • Michele Caputo,
  • Sonia Bisicchia,
  • Matteo Soato,
  • Giacomo Bertolino,
  • Susanna Vaccaro and
  • Rosanna Inturri

Bifidobacteria colonize the human gastrointestinal tract early on in life, their interaction with the host starting soon after birth. The health benefits are strain specific and could be due to the produced polysaccharides. The consumption of probiot...

  • Article
  • Open Access
4 Citations
2,757 Views
13 Pages

Nitric oxide (NO) is a free radical associated with physiological functions such as blood pressure regulation, cardiovascular health, mitochondrial production, calcium transport, oxidative stress, and skeletal muscle repair. This study aimed to isola...

  • Article
  • Open Access
11 Citations
4,015 Views
13 Pages

To understand the biological roles of Pediococcus pentosaceus strains as probiotics isolated from the traditional Korean fermented food, Jangajji, Pediococcus pentosaceus was selected based on its high cinnamoyl esterase (CE) and antioxidant activiti...

  • Review
  • Open Access
47 Citations
9,057 Views
28 Pages

Biological Activities of Lactose-Based Prebiotics and Symbiosis with Probiotics on Controlling Osteoporosis, Blood-Lipid and Glucose Levels

  • Arijit Nath,
  • Máté András Molnár,
  • Attila Csighy,
  • Kornélia Kőszegi,
  • Ildikó Galambos,
  • Klára Pásztorné Huszár,
  • András Koris and
  • Gyula Vatai

3 December 2018

Lactose-based prebiotics are synthesized by enzymatic- or microbial- biotransformation of lactose and have unique functional values. In this comprehensive review article, the biochemical mechanisms of controlling osteoporosis, blood-lipid, and glucos...

  • Article
  • Open Access
6 Citations
4,216 Views
14 Pages

4 June 2021

The yeast Schwanniomyces polymorphus is associated with the infrabuccal pocket in the carpenter ant Camponotus vicinus (Hymenoptera: Formicidae), but its role in ant development is poorly defined. The potential effects of this yeast on brood developm...

  • Article
  • Open Access
5 Citations
2,911 Views
17 Pages

Factor VIIa Regulates the Level of Cell-Surface Tissue Factor through Separate but Cooperative Mechanisms

  • Yahya Madkhali,
  • Araci M. R. Rondon,
  • Sophie Featherby,
  • Anthony Maraveyas,
  • John Greenman and
  • Camille Ettelaie

23 July 2021

Procoagulant activity of tissue factor (TF) in response to injury or inflammation is accompanied with cellular signals which determine the fate of cells. However, to prevent excessive signalling, TF is rapidly dissipated through release into microves...

  • Article
  • Open Access
100 Views
20 Pages

12 January 2026

Lacticaseibacillus rhamnosus WH.FH-19 exhibits robust probiotic and technological traits for fermented dairy applications. L. rhamnosus WH.FH-19 shows superior functional potential compared to the benchmark strain Lacticaseibacillus rhamnosus GG. Kin...

  • Article
  • Open Access
181 Citations
11,639 Views
21 Pages

In Vitro Probiotic Potential and Safety Evaluation (Hemolytic, Cytotoxic Activity) of Bifidobacterium Strains Isolated from Raw Camel Milk

  • Iqra Yasmin,
  • Muhammad Saeed,
  • Wahab Ali Khan,
  • Adnan Khaliq,
  • Muhammad Farhan Jahangir Chughtai,
  • Rabia Iqbal,
  • Saima Tehseen,
  • Saima Naz,
  • Atif Liaqat and
  • Saira Tanweer
  • + 1 author

The present study was designed to isolate Bifidobacterium strains from raw camel milk and to investigate their probiotic characteristics. Among 35 isolates, 8 were identified as Gram-positive, catalase negative, non-spore forming, non-motile and V or...

  • Article
  • Open Access
3 Citations
3,478 Views
27 Pages

A Novel Wild-Type Lacticaseibacillus paracasei Strain Suitable for the Production of Functional Yoghurt and Ayran Products

  • Ioanna Prapa,
  • Chrysoula Pavlatou,
  • Vasiliki Kompoura,
  • Anastasios Nikolaou,
  • Electra Stylianopoulou,
  • George Skavdis,
  • Maria E. Grigoriou and
  • Yiannis Kourkoutas

Raw goat and ewe’s milk samples were used for the isolation of seven lactic acid bacteria new strains. After testing hemolytic activity and resistance to antibiotics, specific functional properties were evaluated; Lactococcus lactis subsp. lact...

  • Article
  • Open Access
270 Views
25 Pages

29 December 2025

This study investigates the adaptive mechanisms that enable a single wild barley (Hordeum spontaneum) accession to withstand extreme salinity. Salt stress reshapes plant metabolism and gene expression, offering targets for breeding salt-tolerant cere...

  • Article
  • Open Access
20 Citations
5,091 Views
11 Pages

Enhanced Ganoderic Acids Accumulation and Transcriptional Responses of Biosynthetic Genes in Ganoderma lucidum Fruiting Bodies by Elicitation Supplementation

  • Li Meng,
  • Xiaoran Bai,
  • Shaoyan Zhang,
  • Mengfei Zhang,
  • Sen Zhou,
  • Irum Mukhtar,
  • Li Wang,
  • Zhuang Li and
  • Wei Wang

Ganoderic acids (GAs) are a type of highly oxygenated lanostane-type triterpenoids that are responsible for the pharmacological activities of Ganoderma lucidum. They have been investigated for their biological activities, including antibacterial, ant...

  • Review
  • Open Access
3 Citations
4,533 Views
23 Pages

Curious Dichotomies of Apolipoprotein E Function in Alzheimer’s Disease and Cancer—One Explanatory Mechanism of Inverse Disease Associations?

  • Claire M. Perks,
  • Rachel M. Barker,
  • Mai Alhadrami,
  • Omar Alkahtani,
  • Emily Gill,
  • Mary Grishaw,
  • Abigail J. Harland,
  • Peter Henley,
  • Haonan Li and
  • Patrick G. Kehoe
  • + 2 authors

12 March 2025

An apparent “inverse” relationship exists between two seemingly unconnected conditions, Alzheimer’s disease (AD) and cancer, despite sharing similar risk factors, like increased age and obesity. AD is associated with amyloid beta (A...

  • Article
  • Open Access
3 Citations
2,205 Views
12 Pages

Bile salt hydrolase (BSH), a probiotic-related enzyme with cholesterol-assimilating and anti-hypercholesterolemic abilities, has been isolated from intestinal bacteria; however, BSH activity of bacteria in bile-salt-free (non-intestinal) environments...

  • Article
  • Open Access
226 Views
20 Pages

2 January 2026

With growing emphasis on antibiotic-free poultry production, functional probiotics represent a promising strategy to improve gut health and reduce pathogen transmission. This study characterized three lactic acid bacteria (LAB) strains Lactobacillus...

  • Article
  • Open Access
11 Citations
3,846 Views
12 Pages

The Prospective Beneficial Effects of Red Laser Exposure on Lactocaseibacillus casei Fermentation of Skim Milk

  • Mahmoud S.M. Mohamed,
  • Fouad M.F. Elshaghabee,
  • Sulaiman Ali Alharbi and
  • Ahmed El-Hussein

31 August 2020

Probiotic lactic acid bacteria are crucial producers of fermented dairy products that are popular functional foods in many countries. The health benefits of probiotic bacteria are mainly attributed to their effective bioactive metabolites. The qualit...