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22 Results Found

  • Review
  • Open Access
76 Citations
11,173 Views
18 Pages

Multiple-Ion Releasing Bioactive Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler: Innovative Technology for Dental Treatment and Care

  • Satoshi Imazato,
  • Toshiyuki Nakatsuka,
  • Haruaki Kitagawa,
  • Jun-Ichi Sasaki and ,
  • Satoshi Yamaguchi,
  • Shuichi Ito,
  • Hiroki Takeuchi,
  • Ryota Nomura and
  • Kazuhiko Nakano
  • + 4 authors+ 0 author

Surface Pre-Reacted Glass-ionomer (S-PRG) filler, which releases strontium (Sr2+), borate (BO33−), fluoride (F−), sodium (Na+), silicate (SiO32−), and aluminum (Al3+) ions at high concentrations, is a unique glass filler that are ut...

(This article belongs to the Special Issue Functional Materials for Dental Restorations)
  • Article
  • Open Access
13 Citations
3,943 Views
16 Pages

Tissue Conditioner Incorporating a Nano-Sized Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler

  • Watcharapong Tonprasong,
  • Masanao Inokoshi,
  • Muneaki Tamura,
  • Motohiro Uo and ,
  • Takahiro Wada,
  • Rena Takahashi,
  • Keita Hatano,
  • Makoto Shimizubata and
  • Shunsuke Minakuchi
  • + 4 authors+ 0 author

4 November 2021

We aimed to evaluate the properties of a novel tissue conditioner containing a surface pre-reacted glass-ionomer (S-PRG) nanofiller. Tissue conditioners containing 0 (control), 2.5, 5, 10, 20, or 30 wt% S-PRG nanofiller or 10 or 20 wt% S-PRG microfil...

(This article belongs to the Special Issue Anti-Infective Materials)
  • Article
  • Open Access
15 Citations
3,354 Views
12 Pages

Controlling the oral microbial flora is putatively thought to prevent not only oral diseases, but also systemic diseases caused by oral diseases. This study establishes the antibacterial effect of the novel bioactive substance “S-PRG filler” on oral...

  • Article
  • Open Access
6 Citations
2,988 Views
14 Pages

The Effect of Mechanical Alteration on Repair Bond Strength of S-PRG-Filler-Based Resin Composite Materials

  • Md Sofiqul Islam,
  • Smriti Aryal A C,
  • Shadi El Bahra,
  • Abdullah Jamal Abuhajjeh and ,
  • Akram Mohammad Al Mofleh,
  • Vivek Padmanabhan and
  • Muhammed Mustahsen Rahman
  • + 2 authors+ 0 author

24 May 2024

This study investigates the impact of mechanical alteration on resin composite surfaces and its subsequent effect on repair bond strength. A total of 100 resin composite disks were prepared and were allocated for 24 h or 1 year of artificial aging. S...

(This article belongs to the Special Issue Functional Polymer Composites: Synthesis, Characterization and Application II)
  • Article
  • Open Access
34 Citations
5,135 Views
12 Pages

Protective Effects of GIC and S-PRG Filler Restoratives on Demineralization of Bovine Enamel in Lactic Acid Solution

  • Naoyuki Kaga,
  • Futami Nagano-Takebe,
  • Takashi Nezu,
  • Takashi Matsuura and ,
  • Kazuhiko Endo and
  • Masayuki Kaga
  • + 1 author+ 0 author

6 May 2020

This study was aimed at investigating the protective effects of glass ionomer cement (GIC) and surface pre-reacted glass ionomer (S-PRG) fillers used as dental restorative materials on demineralization of bovine enamel. GlasIonomer FX ULTRA (FXU), Fu...

(This article belongs to the Collection Dental Biomaterials)
  • Article
  • Open Access
8 Citations
3,176 Views
12 Pages

3 March 2023

Herein, the mechanical properties of an auto-polymerizing resin incorporated with a surface pre-reacted glass ionomer (S-PRG) filler were evaluated. For this, S-PRG fillers with particle sizes of 1 μm (S-PRG-1) and 3 μm (S-PRG-3) were mixed at...

(This article belongs to the Special Issue Dentistry Journal: 10th Anniversary)
  • Article
  • Open Access
4 Citations
2,744 Views
12 Pages

Inhibitory Effects of Surface Pre-Reacted Glass Ionomer Filler Eluate on Streptococcus mutans in the Presence of Sucrose

  • Mariko Kametani,
  • Tatsuya Akitomo,
  • Masakazu Hamada,
  • Momoko Usuda and ,
  • Ami Kaneki,
  • Masashi Ogawa,
  • Shunya Ikeda,
  • Yuya Ito,
  • Shuma Hamaguchi and
  • Ryota Nomura
  • + 12 authors+ 7 authors

2 September 2024

The surface pre-reacted glass ionomer (S-PRG) filler is a type of bioactive functional glass that releases six different ions. This study examined the effects of the S-PRG filler eluate on Streptococcus mutans in the presence of sucrose. In a solutio...

(This article belongs to the Special Issue Dental Health and Disease: From the Molecular and Pathological Perspectives)
  • Article
  • Open Access
12 Citations
3,860 Views
11 Pages

A Novel Bioactive Endodontic Sealer Containing Surface-Reaction-Type Prereacted Glass-Ionomer Filler Induces Osteoblast Differentiation

  • Nobuyuki Kawashima,
  • Kentaro Hashimoto,
  • Masashi Kuramoto,
  • Alamuddin Bakhit and ,
  • Yasumiko Wakabayashi and
  • Takashi Okiji
  • + 1 author+ 0 author

9 October 2020

Surface-reaction-type prereacted glass-ionomer (S-PRG) fillers exhibit bioactive properties by the release of multiple ions. This study examined whether a novel endodontic sealer containing S-PRG fillers (PRG+) has the capacity to induce osteoblast d...

(This article belongs to the Special Issue Contemporary Endodontic Materials)
  • Article
  • Open Access
3 Citations
2,114 Views
13 Pages

Bioactive Self-Polymerizing Resin with Surface Pre-Reacted Glass Ionomer Fillers for Suppressed Enamel Demineralization

  • Naoyuki Kaga,
  • Masayuki Kaga,
  • Sho Morita,
  • Futami Nagano-Takebe and ,
  • Takashi Nezu,
  • Kazuhiko Endo and
  • Takashi Matsuura
  • + 2 authors+ 0 author

18 October 2024

The treatment of damaged enamel surfaces involves modification of the enamel surface with artificial materials or the development of a pseudo-enamel, with research focusing on bioactive and biomimetic materials. In this study, a bioactive auto-polyme...

  • Article
  • Open Access
3 Citations
2,657 Views
15 Pages

18 November 2022

A unique type of dental varnish (DV) containing surface pre-reacted glass (S-PRG) fillers of different concentrations was evaluated to determine the unpresented optimal ratio for inhibiting root dentin bio-demineralization. S-PRG DVs (10% to 40%)&mda...

(This article belongs to the Special Issue Advanced Polymeric Materials for Dental Applications)
  • Article
  • Open Access
7 Citations
4,723 Views
18 Pages

Long-Term Dentin Bonding Performance of Universal Adhesives: The Effect of HEMA Content and Bioactive Resin Composite

  • Di Wu,
  • Ye Yao,
  • Carolina Cecilia Cifuentes-Jimenez,
  • Hidehiko Sano and ,
  • Pedro Álvarez-Lloret,
  • Monica Yamauti and
  • Atsushi Tomokiyo
  • + 2 authors+ 0 author

16 December 2024

This study investigated the effects of resin composites (RCs) containing surface pre-reacted glass ionomer (S-PRG) filler on the dentin microtensile bond strength (μTBS) of HEMA-free and HEMA-containing universal adhesives (UAs). Water sorption (W...

(This article belongs to the Special Issue Recent Advances in Dental Resin Composites)
  • Case Report
  • Open Access
7 Citations
4,039 Views
9 Pages

Surgical Sealing of Laterally Localized Accessory Root Canal with Resin Containing S-PRG Filler in Combination with Non-Surgical Endodontic Treatment: A Case Report

  • Shizu Hirata-Tsuchiya,
  • Shigeki Suzuki,
  • Takashi Nakamoto,
  • Naoya Kakimoto and ,
  • Satoru Yamada and
  • Hideki Shiba
  • + 1 author+ 0 author

20 November 2020

The spread of root canal infection to surrounding periodontal tissue through accessory root canals reduces the success rate of endodontic treatment. In this case, cone-beam computed tomography revealed a lesion (4 mm from the apex) resulting from an...

(This article belongs to the Section Dental Materials)
  • Article
  • Open Access
4 Citations
2,332 Views
16 Pages

Surface Pre-Reacted Glass-Ionomer Eluate Suppresses Osteoclastogenesis through Downregulation of the MAPK Signaling Pathway

  • Janaki Chandra,
  • Shin Nakamura,
  • Satoru Shindo,
  • Elizabeth Leon and ,
  • Maria Castellon,
  • Maria Rita Pastore,
  • Alireza Heidari,
  • Lukasz Witek,
  • Paulo G. Coelho and
  • Toshihisa Kawai
  • + 6 authors+ 1 author

Surface pre-reacted glass-ionomer (S-PRG) is a new bioactive filler utilized for the restoration of decayed teeth by its ability to release six bioactive ions that prevent the adhesion of dental plaque to the tooth surface. Since ionic liquids are re...

(This article belongs to the Special Issue Osteoclast and Osteoblast: Current Status and Future Prospects)
  • Article
  • Open Access
12 Citations
3,396 Views
12 Pages

Antibacterial Activity of a Bioactive Tooth-Coating Material Containing Surface Pre-Reacted Glass in a Complex Multispecies Subgingival Biofilm

  • Caio Junji Tanaka,
  • José Augusto Rodrigues,
  • João Marcos Spessoto Pingueiro,
  • Tatiane Tiemi Macedo and ,
  • Magda Feres,
  • Jamil Awad Shibli and
  • Bruno Bueno-Silva
  • + 2 authors+ 0 author

Bioactive materials were developed with the ability to release fluoride and provide some antimicrobial potential, to be widely used in dentistry today. However, few scientific studies have evaluated the antimicrobial activity of bioactive surface pre...

(This article belongs to the Special Issue Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental Research)
  • Article
  • Open Access
161 Views
13 Pages

Surface Roughness and Color Stability of S-PRG Giomer Flowable Restoratives Versus Nanofill Resin Composites After Simulated Toothbrushing: An In Vitro Study

  • Yasser Merdad,
  • Razan Alharbi,
  • Abeer Tashkandi,
  • Renad Bakhaider and ,
  • Asaad H. Doum and
  • Mohammed A. Hanbazazah
  • + 1 author+ 0 author

22 October 2026

This in vitro study compared surface roughness (Ra) and CIEDE2000 color change (ΔE00) of two giomer flowables with surface pre-reacted glass-ionomer (S-PRG) filler, Beautifil Flow Plus F00 and Beautifil Flow Plus X F00, and two nanofill resin c...

(This article belongs to the Section Polymer Applications)
  • Article
  • Open Access
5 Citations
2,954 Views
14 Pages

Effect of an In-Office Bleaching Agent with Surface Pre-Reacted Glass-Ionomer Filler on the Enamel Surface: A In-Vitro Study

  • Mika Shimojima,
  • Noriko Hiraishi,
  • Kodai Akabane,
  • Mohannad Nassar and ,
  • Masayuki Otsuki and
  • Yasushi Shimada
  • + 1 author+ 0 author

In-office bleaching with high concentrations of hydrogen peroxide (H2O2) agents causes undesirable alterations in the enamel. Surface pre-reacted glass-ionomer (S-PRG) filler is a functional material known for its acid-neutralizing and demineralizati...

(This article belongs to the Special Issue Functional Materials for Dental Restorations)
  • Article
  • Open Access
3 Citations
4,096 Views
13 Pages

Resin Composite Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler for Non-Carious Cervical Lesions: A Double-Blinded, Randomized, Split-Mouth Clinical Trial

  • Adam Lowenstein,
  • Carlos Fernando Mourão,
  • Mabi L. Singh,
  • Sarah E. Pagni and ,
  • Ronald D. Perry and
  • Gerard Kugel
  • + 1 author+ 0 author

1 April 2025

Background/Objectives: This double-blinded study aimed to evaluate the clinical performance of a giomer restorative material in comparison to a nanotechnology-based restorative system for the restoration of non-carious cervical lesions over a period...

(This article belongs to the Special Issue Advances in Esthetic Dentistry)
  • Article
  • Open Access
22 Citations
4,309 Views
11 Pages

Effect of Surface Pre-Reacted Glass Ionomer Containing Dental Sealant on the Inhibition of Enamel Demineralization

  • Yuko Ogawa,
  • Mahmoud Sayed,
  • Noriko Hiraishi,
  • Nadin Al-Haj Husain and ,
  • Junji Tagami,
  • Mutlu Özcan and
  • Yasushi Shimada
  • + 2 authors+ 0 author

The effect of a surface pre-reacted glass ionomer (S-PRG)-containing sealant on the demineralization inhibition and remineralization of intact enamel adjacent to the sealant material was investigated. BeautiSealant (BTS, S-PRG sealant, Shofu), Teeth...

(This article belongs to the Special Issue Functional Materials for Dental Restorations)
  • Article
  • Open Access
43 Citations
6,323 Views
20 Pages

New Pre-reacted Glass Containing Dental Composites (giomers) with Improved Fluoride Release and Biocompatibility

  • Loredana Colceriu Burtea,
  • Cristina Prejmerean,
  • Doina Prodan,
  • Ioana Baldea and ,
  • Mihaela Vlassa,
  • Miuta Filip,
  • Marioara Moldovan,
  • Madalina-Anca Lazar (Moldovan),
  • Aurora Antoniac and
  • Ioana Ambrosie
  • + 6 authors+ 1 author

3 December 2019

The aim of the present work was to prepare a series of novel restorative giomers and investigate the morphology, the physico-chemical properties (residual monomer, fluoride release), and the cytotoxicity of the new materials. The experimental giomers...

(This article belongs to the Special Issue Selected Papers from BIOMMEDD 2018 Conference—Biomaterials)
  • Review
  • Open Access
866 Views
34 Pages

Bioactive Fillers in Bulk-Fill Composite Resins: A Comprehensive Review of the Effects on Polymerization Shrinkage Behavior and Mechanical Performance

  • Vlad Constantin,
  • Ionut Luchian,
  • Ionut Taraboanta,
  • Teona Anamaria Tudorici and ,
  • Nicoleta Tofan,
  • Florinel Cosmin Bida,
  • Florin Razvan Curca,
  • Dana Gabriela Budala,
  • Dragos Ioan Virvescu and
  • Andrei Georgescu
  • + 5 authors+ 0 author

22 May 2026

Polymerization shrinkage remains a primary cause of marginal failure in posterior composite restorations, contributing to interfacial gap formation and secondary caries development. Bioactive filler technologies represent a paradigm shift, offering s...

(This article belongs to the Special Issue Advanced Bioactive Materials and Bulk-Fill Composite Resins in Dental Restorations)
  • Systematic Review
  • Open Access
1 Citations
210 Views
24 Pages

Remineralizing Composites: A Systematic Review of In Vitro Studies

  • Adriana Martínez-Llop,
  • Jose Luis Sanz,
  • Sofia Folguera,
  • Álvaro Villanueva-Castellote and ,
  • Ana Paredes and
  • James Ghilotti
  • + 1 author+ 0 author

22 October 2026

Dental caries disrupt the balance between demineralization and remineralization in dentin, a complex mineralized tissue whose recovery requires not only mineral redeposition but also reconstitution of the collagen-apatite hierarchical organization. R...

(This article belongs to the Special Issue Bioactive Dental Restorative Composite Materials)
  • Article
  • Open Access
4 Citations
3,135 Views
13 Pages

Effect of Fly Ash on Mechanical Properties of Polymer Resin Grout

  • Ashraf A. M. Fadiel,
  • Nuria S. Mohammed,
  • Ahmad Baharuddin Abdul Rahman,
  • Esam Abu Baker Ali and ,
  • Taher Abu-Lebdeh and
  • Florian Ion Tiberiu Petrescu
  • + 1 author+ 0 author

High-strength grout is specified to increase the bond between grout and bar in grouted connections and to ensure that the forces in the bars can be transferred to the surrounding material accordingly. Although polymer grout is fast setting and rapid...

(This article belongs to the Special Issue Advances in Biomaterials, Biocomposites and Biopolymers)