Skip to Content

9 Results Found

  • Article
  • Open Access
1 Citations
3,004 Views
11 Pages

Circulatory miRNAs as Correlates of Elevated Intra-Pancreatic Fat Deposition in a Mixed Ethnic Female Cohort: The TOFI_Asia Study

  • Farha Ramzan,
  • Ivana R. Sequeira-Bisson,
  • Louise W. Lu,
  • Cameron J. Mitchell and ,
  • Randall F. D’Souza,
  • Mark H. Vickers,
  • Sally D. Poppitt and
  • David Cameron-Smith
  • + 3 authors+ 0 author

21 September 2023

Ectopic lipid accumulation, including intra-pancreatic fat deposition (IPFD), exacerbates type 2 diabetes risk in susceptible individuals. Dysregulated circulating microRNAs (miRNAs) have been identified as correlating with clinical measures of pancr...

(This article belongs to the Special Issue The Role of microRNA in Human Diseases 2.0)
  • Review
  • Open Access
1 Citations
944 Views
15 Pages

Pancreatic Steatosis as a Risk Phenotype for Pancreatic Ductal Adenocarcinoma: A Narrative Review

  • Roberto Cammarata,
  • Vincenzo La Vaccara,
  • Lucrezia Bani,
  • Federica Giordano and ,
  • Pierpaolo Castagliuolo,
  • Maria Vittoria Ristori,
  • Sara Elsa Aita,
  • Silvia Angeletti,
  • Roberto Coppola and
  • Damiano Caputo
  • + 5 authors+ 0 author

10 April 2026

Background and Objectives: Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related mortality, largely due to late-stage diagnosis and the absence of effective population-based screening. Intrapancreatic fat deposition (...

(This article belongs to the Special Issue Pancreatic Cancer: Advances in Treatment and Future Prospects)
  • Article
  • Open Access
1 Citations
1,583 Views
25 Pages

Characterization of Novel Variants in P2YRY12, GP6 and TBXAS1 in Patients with Lifelong History of Bleeding

  • Ana Zamora-Cánovas,
  • Ana Marín-Quílez,
  • Lorena Díaz-Ajenjo,
  • Ana Sánchez-Fuentes and ,
  • Pedro Luis Gómez-González,
  • Marilena Crescente,
  • Nuria Fernández-Mosteirín,
  • José Padilla,
  • José Ramón González-Porras and
  • José Rivera Pozo
  • + 8 authors+ 3 authors

21 November 2025

Inherited platelet function disorders (IPFDs) are rare diseases caused by defects in platelet surface receptors, enzymes, granules, or signaling proteins. In humans, GPVI and P2Y12 deficiency cause autosomal recessive bleeding disorders, while TBXAS1...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
325 Views
14 Pages

Clinical Features and Immunological Markers Associated with Invasive Pulmonary Fungal Disease in Organizing Pneumonia: A Matched Case–Control Study

  • Longzhen Lu,
  • Yun Li,
  • Zhiwei Long,
  • Lejin Liang and ,
  • Xidong Wang,
  • Hongling Liu,
  • Juan Cao,
  • Shaoqiang Li,
  • Yan Wang and
  • Feng Ye
  • + 6 authors+ 1 author

23 September 2026

Background/Objectives: Invasive pulmonary fungal disease (IPFD) is a serious complication of organizing pneumonia (OP), but associated clinical and immunological features remain poorly defined. Methods: We conducted a retrospective 1:2 age- and sex-m...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
793 Views
11 Pages

Influence of Intrapancreatic Fat Deposition on Regional and Total Pancreatic T1 Relaxation Times at 3.0 Tesla MRI

  • Xiatiguli Shamaitijiang,
  • Beau Pontre,
  • Loren Skudder-Hill,
  • Yutong Liu and
  • Maxim S. Petrov

Longitudinal relaxation time (T1) can be used to assess pancreatic pathology on magnetic resonance imaging (MRI). Although pancreatic T1 values may be influenced by intra-organ fat content, regional variation within the pancreas and the impact of pot...

(This article belongs to the Special Issue Advancing Magnetic Resonance Imaging: Emerging Technologies, Computation, and Clinical Applications)
  • Article
  • Open Access
3 Citations
938 Views
13 Pages

Dysapolipoproteinaemia Influences the Relationship Between Very Low-Density Lipoprotein Cholesterol and Intra-Pancreatic Fat Deposition in Humans

  • Yutong Liu,
  • Loren Skudder-Hill,
  • Juyeon Ko,
  • Xiatiguli Shamaitijiang and ,
  • Ivana R. Sequeira-Bisson and
  • Maxim S. Petrov
  • + 1 author+ 0 author

27 November 2025

Background: Apolipoprotein B (apo B), apolipoprotein C-II (apo C-II), and apolipoprotein C-III (apo C-III) play important roles in very low-density lipoprotein (VLDL) metabolism. Whether they influence the relationship between intra-pancreatic fat de...

(This article belongs to the Special Issue The Role of Lipids and Lipoproteins in Health)
  • Article
  • Open Access
4 Citations
4,091 Views
8 Pages

Genetic Confirmation and Identification of Novel Variants for Glanzmann Thrombasthenia and Other Inherited Platelet Function Disorders: A Study by the Korean Pediatric Hematology Oncology Group (KPHOG)

  • Eu Jeen Yang,
  • Ye Jee Shim,
  • Heung Sik Kim,
  • Young Tak Lim and ,
  • Ho Joon Im,
  • Kyung-Nam Koh,
  • Hyery Kim,
  • Jin Kyung Suh,
  • Eun Sil Park and
  • on behalf of the Benign Hematology Committee of the Korean Pediatric Hematology Oncology Group (KPHOG)
  • + 15 authors+ 10 authors

6 May 2021

The diagnosis of inherited platelet function disorders (IPFDs) is challenging owing to the unavailability of essential testing methods, including light transmission aggregometry and flow cytometry, in several medical centers in Korea. This study, con...

(This article belongs to the Special Issue Genetics of Rare Disease)
  • Review
  • Open Access
13 Citations
8,366 Views
15 Pages

Fatty Pancreas: Its Potential as a Risk Factor for Pancreatic Cancer and Clinical Implications

  • Nao Otsuka,
  • Yutaka Shimamatsu,
  • Ryunosuke Hakuta,
  • Yukiko Takayama and
  • Yousuke Nakai

24 May 2025

With the increasing use of imaging modalities such as ultrasonography, computed tomography, and magnetic resonance imaging, incidental findings of pancreatic abnormalities, including pancreatic cysts and fatty pancreas (FP), have become more common....

(This article belongs to the Special Issue Screening, Early Detection and Prevention of Hepato-Pancreato-Biliary (HPB) Cancers)
  • Review
  • Open Access
7 Citations
4,291 Views
21 Pages

Molecular Pathogenesis of Inherited Platelet Dysfunction

  • Agustín Rodríguez-Alén,
  • Antonio Moscardó,
  • José M. Bastida and
  • José Rivera

30 October 2025

Inherited platelet function disorders (IPFD) are characterized by normal platelet count and morphology but impaired function due to pathogenic variants in genes encoding membrane receptors, granule constituents, or intracellular signaling proteins. G...

(This article belongs to the Section Molecular Biology)