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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Vaccination Against Tick-Borne Pathogens

edited by

Artur Sulik

and

Kacper Toczylowski

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2651 | Submission Open

Keywords: tick-borne diseases; tick-borne encephalitis; Lyme disease; Lyme disease vaccine; ticks; immunization

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Immunogenicity, Safety, and Coverage of Vaccines in Patients with Autoimmune Diseases

edited by

Andrea Picchianti-Diamanti

and

Delia Goletti

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2283 | Submission Open

Keywords: vaccines; systemic autoimmune diseases; bDMARDs; tsDMARDs; immunosuppressive therapy; adverse events; immunogenicity; coverage rates; specific T cell response

(This special issue belongs to the Section Innate and Adaptive Immunity in Vaccination)

Vaccines for Porcine Viruses

edited by Hongxia Wu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1676 | Submission Open

Keywords: infections; vaccine; adaptive immune response; epidemiology

(This special issue belongs to the Section Veterinary Vaccines)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1619 | Submission Open

Keywords: vaccine; antigen; antibody; adjuvant; HLA; binding affinity; lymphocytes; antigen presenting cells

(This special issue belongs to the Section Pathogens-host Immune Interface)

Cytokines and Cytokine Receptors in Inflammation and Immunity

edited by

Pedro A. Reche

and Vassili Soumelis

submission deadline 31 Jul 2025 | Viewed by 230 | Submission Open

Keywords: cytokine; cytokine receptors; chemokine; inlammation; immunity; signaling; immunotherapy

Treating Autoimmune Diseases with Vaccination

edited by

Ritu Chakravarti

submission deadline 31 Jul 2025 | Viewed by 220 | Submission Open

Keywords: autoimmune disease; immune regulations; immune tolerance; antigen therapy; vaccine; immunizations

(This special issue belongs to the Section Innate and Adaptive Immunity in Vaccination)

State of the Art of Flavivirus Virus Research

edited by

Tomoyoshi Komiya

submission deadline 31 Jul 2025 | Viewed by 173 | Submission Open

Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Recent Scientific Advances in Vaccination Strategies for Viral Haemorrhagic Fevers

edited by

Daniela Manno

submission deadline 31 Jul 2025 | Viewed by 130 | Submission Open

Keywords: viral haemorrhagic fevers; Ebola virus disease; Sudan virus disease; Marburg virus disease; Lassa fever; Rift Valley fever; Crimean– Congo haemorrhagic fever; vaccination strategies; outbreak preparedness; epidemiology of VHFs

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Recent Research on Neutralizing Antibody Response to SARS-CoV-2 Variants

edited by

Chloé Dimeglio

submission deadline 6 Aug 2025 | 2 articles | Viewed by 2873 | Submission Open

Keywords: SARS-CoV-2 and vaccines; SARS-CoV-2 and natural infection; immunity mechanism; competition between variants; SARS-CoV-2 dynamics

(This special issue belongs to the Section Innate and Adaptive Immunity in Vaccination)

Veterinary Vaccines and Host Immune Responses

edited by Ayumi Matsuyama-Kato and

Faizal Careem

submission deadline 13 Aug 2025 | 8 articles | Viewed by 9394 | Submission Open

Keywords: animal vaccine; vaccine delivery; immune response; adjuvant; antibody-mediated immunity; cell-mediated immunity; immunogenicity; veterinary immunology

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Acceptance and Coverage

edited by

Ryoko Sato

and

Christian Napoli

submission deadline 15 Aug 2025 | 2 articles | Viewed by 3188 | Submission Open

Keywords: vaccine; vaccination; vaccine acceptance; vaccine hesitancy; vaccination coverage; immunization coverage

(This special issue belongs to the Section Human Vaccines and Public Health)

Immune Correlates of Protection in Vaccines, 2nd Edition

edited by

Jingyou Yu

submission deadline 16 Aug 2025 | 1 articles | Viewed by 1365 | Submission Open

Keywords: vaccine; humoral immunity; cellular immunity; innate immunity; infectious disease; virus; cancer

(This special issue belongs to the Section Innate and Adaptive Immunity in Vaccination)

Impact of Immunization Safety Monitoring on Vaccine Coverage

edited by Jane F. Gidudu

submission deadline 25 Aug 2025 | 8 articles | Viewed by 9453 | Submission Open

Keywords: vaccine safety; immunization safety; adverse events following immunization; vaccination coverage; vaccine hesitancy; pharmacovigilance; information systems; active surveillance; mis- and dis-information

(This special issue belongs to the Section Human Vaccines and Public Health)

Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Aug 2025 | Viewed by 286 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Clinical Immunology)

New Trends in Vaccine Characterization, Formulations, and Development

edited by

Ravinder Kumar

submission deadline 31 Aug 2025 | 12 articles | Viewed by 49765 | Submission Open

Keywords: vaccines; formulation; development; vaccine delivery; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; yeast-based vaccines; virus-like particles (VLPs); surface display; production process; quality control

Biotechnologies Applied in Vaccine Research

edited by

Yuan-Chuan Chen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 19697 | Submission Open

Keywords: vaccine; biotechnology; vector; nanoparticle; virus; bacteria; recombination DNA; mRNA; subunit; adjuvant; delivery

Strategies of Viral Vectors for Vaccine Development

edited by

Kathleen Hefferon

submission deadline 31 Aug 2025 | 7 articles | Viewed by 13850 | Submission Open

Keywords: vaccine; viral vector; virus-like particles

(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)

Vaccine Uptake in Italy, Through the OBVIOUS Project and Other Independent Research

edited by

Jacopo Lenzi

and

Davide Gori

submission deadline 31 Aug 2025 | 6 articles | Viewed by 13309 | Submission Open

Keywords: vaccine uptake; vaccine hesitancy; vaccination rates; Italy

(This special issue belongs to the Section Epidemiology)

Novel Vaccines and Vaccine Technologies for Emerging Infections

edited by

Wangxue Chen

Xuguang Li

and

Amine A. Kamen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 12963 | Submission Open

Keywords: novel vaccines and adjuvant; universal vaccines; mucosal vaccines; emerging infections; antimicrobial resistance; systems vaccinology; vaccine production

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines Targeting the Tumor Microenvironment: Challenges and Future Prospects

edited by

Walter J. Storkus

and Devin Lowe

submission deadline 31 Aug 2025 | 8 articles | Viewed by 11534 | Submission Open

Keywords: vaccine; adoptive cell therapy; CAR-T cells; immune checkpoint inhibitors; immunotherapy; stroma; tumor microenvironment

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Advancing the Science on Vaccine Hesitancy to Inform Interventions

edited by Kimberly H. Nguyen and

Jennifer Allen

submission deadline 31 Aug 2025 | 6 articles | Viewed by 10386 | Submission Open

Keywords: vaccine hesitancy; vaccine confidence; COVID-19; routinely recommended vaccines; epidemiologic methods; conceptual frameworks; strategies; surveillance

(This special issue belongs to the Section Human Vaccines and Public Health)

Advances in Glycoconjugate Vaccines and Nanovaccines

edited by

Marco Terreni

and

Sara Tengattini

submission deadline 31 Aug 2025 | 4 articles | Viewed by 9766 | Submission Open

Keywords: glycoconjugate vaccines; infection diseases; anticancer vaccines; glycosylated nanovaccines; antigenic saccharides; conjugation chemistry; glycoconjugate characterization; dual-acting vaccines; glycosylated nanoparticles

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Respiratory Syncytial Virus (RSV) Vaccine

edited by

Surender Khurana

submission deadline 31 Aug 2025 | 3 articles | Viewed by 7225 | Submission Open

Keywords: respiratory syncytial virus (RSV); RSV vaccine development; viral vector vaccines; subunit vaccines; prefusion protein design; mRNA vaccines; vaccine efficacy; immunization strategies

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Role of Gut Microbiota in Immune Tolerance and Vaccine Development

edited by

Sin-Hyeog Im

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5351 | Submission Open

Keywords: immune tolerance; subtype of immune cells; microbiome; probiotics; T cells; B cells; dendritic cells; antigen-presenting cells

(This special issue belongs to the Section Clinical Immunology)

Understanding Infectious Disease Vaccinations: Implications for Health and Safety

edited by

Daniel Kwasi Ahorsu

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2108 | Submission Open

Keywords: vaccination; infectious disease; health; wellbeing; knowledge; attitudes

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccine Hesitancy and Acceptance: A Public Health Perspective

edited by

Neli Ragina

and

Michael J. Conway

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1492 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; public health; vaccine uptake; misinformation; risk perception; health communication; immunization rates; herd immunity; behavioral determinants; social determinants; trust in healthcare; vaccine misinformation; vaccine education; vaccine refusal; vaccine policy; health disparities

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccination Against Vector-Borne Diseases: Bridging Public Health and Epidemiology

edited by

Angela Stufano

and

Claudia Maria Trombetta

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1204 | Submission Open

Keywords: vector-borne diseases; vaccination strategies; epidemiology; public health integration; disease prevention

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Childhood Immunization and Public Health

edited by Carsten Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 933 | Submission Open

Keywords: compulsory/mandatory vaccination; coverage; local vaccination culture; pandemics; trust; vaccination frameworks; vaccine equity; vaccine hesitancy; zero-dose

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition

edited by

Arturo Reyes-Sandoval

and

Young Chan Kim

submission deadline 31 Aug 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Strategies for Addressing Vaccine Hesitancy

edited by

Donald J. Alcendor

submission deadline 31 Aug 2025 | Viewed by 585 | Submission Open

Keywords: vaccines; vaccine hesitancy; vaccine uptake; vaccine misinformation; vaccine disparities

(This special issue belongs to the Section Human Vaccines and Public Health)

The 2nd Edition: Non-Specific Protection in the Response to Vaccination and Other Immune Stimulation

edited by

François Meurens

Fanny Renois

and

Jianzhong Zhu

submission deadline 31 Aug 2025 | Viewed by 432 | Submission Open

Keywords: non-specific protections; vaccination; non-specific effects (NSEs); trained immunity; immune system; pathogens

(This special issue belongs to the Section Pathogens-host Immune Interface)

Studies of Infectious Disease Epidemiology and Vaccination

edited by

Jose Gonzales-Zamora

and Shweta Anjan

submission deadline 31 Aug 2025 | Viewed by 356 | Submission Open

Keywords: vaccine effectiveness; vaccination policies; cost-effectiveness; surveillance; public health; high-risk population; infectious diseases

(This special issue belongs to the Section Epidemiology)

Vaccination Advances for HBV, HPV, and Influenza

edited by

Wangnan Cao

submission deadline 31 Aug 2025 | Viewed by 267 | Submission Open

Keywords: HBV; HPV; influenza; vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 31 Aug 2025 | Viewed by 251 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Modulating CD4+ T Cells for Cancer Immunotherapy: Emerging Strategies and Applications

edited by

Haval Shirwan

submission deadline 1 Sep 2025 | 2 articles | Viewed by 4508 | Submission Open

Keywords: CD4+ T cells; immunomodulation; cancer immunotherapy; cancer vaccines; immunotherapeutic agents

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Virus Pandemics and Vaccinations

edited by Renata Gili,

Davide Gori

and

Matteo Riccò

submission deadline 1 Sep 2025 | 3 articles | Viewed by 3304 | Submission Open

Keywords: vaccine; vaccination strategy; one health; emerging pathogens; vaccine hesitancy

(This special issue belongs to the Section Human Vaccines and Public Health)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 1 Sep 2025 | Viewed by 313 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Maternal and Infant Vaccines

edited by Prabha Andraweera and Bing Wang

submission deadline 20 Sep 2025 | Viewed by 127 | Submission Open

Keywords: maternal vaccines; infant vaccines; immunogenicity; effectiveness; vaccine uptake; safety

Vaccination Strategies for Global Public Health

edited by

Mathumalar Fahrni

and

Antonio Ivan Lazzarino

submission deadline 30 Sep 2025 | 14 articles | Viewed by 28657 | Submission Open

Keywords: emerging infectious disease; SARS-CoV-2; human monkeypox; dengue; henipavirus; public health; population-based studies; modelling; social impact; equitable access; vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Sep 2025 | 11 articles | Viewed by 20571 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Peptide-Based Vaccines

edited by

Waleed Hussein

Mariusz Skwarczynski

and Ahmed O. Shalash

submission deadline 30 Sep 2025 | 4 articles | Viewed by 6605 | Submission Open

Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants

Role of Next Generation Vaccines in Immunotherapeutics

edited by Swayam Prakash

submission deadline 30 Sep 2025 | 4 articles | Viewed by 6333 | Submission Open

Keywords: immunotherapeutics; vaccines; nucleic acid vaccines; viral vector and protein subunit vaccines; cancer vaccines; autoimmune diseases and allergies; COVID-19; clinical trials; pre-clinical trials

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4714 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Development of Vaccines Against Bacterial Infections

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2282 | Submission Open

Keywords: novel vaccine formulations; bacterial pathogenesis mechanisms; immunogenicity assessment; vaccine efficacy studies; next-generation vaccine platforms; targeted antigen design; novel adjuvants; vaccine clinical trials; vaccine delivery systems; vaccine cross-protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Hepatitis Vaccines: Safety, Efficacy and Global Impact

edited by

Muhammad Atif Zahoor

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2191 | Submission Open

Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges

(This special issue belongs to the Section Hepatitis Virus Vaccines)

3rd Edition: Safety and Autoimmune Response to SARS-CoV-2 Vaccination

edited by

Minghui Yang

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1287 | Submission Open

Keywords: COVID-19 vaccine; vaccine efficacy; vaccine safety; adverse events following immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Vaccine Hesitancy and Acceptance

edited by Karl Hess, Jeff Goad and Laressa Bethishou

submission deadline 30 Sep 2025 | 1 articles | Viewed by 969 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; barriers to vaccination; vaccination strategies

(This special issue belongs to the Section Human Vaccines and Public Health)

Oral and Nucleic Acid Vaccines for Zoonotic and Animal Infectious Diseases

edited by Lei Shuai

submission deadline 30 Sep 2025 | 1 articles | Viewed by 557 | Submission Open

Keywords: oral vaccines; nucleic acid vaccines; zoonotic diseases; animal infectious diseases; vaccine development; vaccine safety; vaccine efficacy; immunological mechanism

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Hesitancy in the Era of COVID-19

edited by