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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Veterinary Vaccine Development and Immunoprophylaxis for Livestock Diseases

edited by

Viviana Parreno

and

Marina Bok

submission deadline 28 Feb 2026 | Viewed by 217 | Submission Open

Keywords: livestock vaccines; veterinary immunoprophylaxis; antibody-based vaccines; nanobodies; passive immunization strategies; One Health vaccinology; sustainable animal health

(This special issue belongs to the Section Veterinary Vaccines)

Advances in Vaccines Against Infectious Diseases

edited by

Salvatore Giovanni De Simone

submission deadline 1 Mar 2026 | 17 articles | Viewed by 52143 | Submission Open

Keywords: vaccination; antigens; disease; immune; immunity; vaccine delivery; host responses; biodefence; emerging pathogens; MERS; parasites; virus; bacteria; adjuvants

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

African Swine Fever Virus Immunotherapies and Vaccine Development

edited by

Tao Feng

and Xiaodong Qin

submission deadline 1 Mar 2026 | 1 articles | Viewed by 1625 | Submission Open

Keywords: ASFV; vaccine development; pathogenesis; immune evasion; diagnostic tools and technologies

(This special issue belongs to the Section Veterinary Vaccines)

Innovations in Vaccines for Poorly Responding Populations

edited by Martha Alexander-Miller and Kenneth E. Schmader

submission deadline 15 Mar 2026 | Viewed by 377 | Submission Open

Keywords: vaccines; infants; newborns; elderly; immunocompromised; high-risk populations; adjuvants; novel vacine platforms; correlates of protection; vaccine effectiveness

Advances in Cancer Immunotherapy and Vaccines Research: 2nd Edition

edited by

Takumi Kumai

submission deadline 20 Mar 2026 | 8 articles | Viewed by 27944 | Submission Open

Keywords: tumor vaccine; immune adjuvants; tumor immune environment; peptide vaccine; chemoradiotherapy; cytokines; suppressive immune cells; checkpoint inhibitors

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advancements in Vaccine Research: Epidemiology, Immunogenicity, Effectiveness and Safety

edited by

Chloé Dimeglio

submission deadline 20 Mar 2026 | 6 articles | Viewed by 13664 | Submission Open

Keywords: vaccine epidemiology; immune response; immunogenicity; vaccine effectiveness; safety; infectious diseases; public health; vaccine development; immunization strategies

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Innovative Strategies to Boost the Immunogenicity of Cancer Vaccines

edited by Eric O'Neill and

Shisong Jiang

submission deadline 20 Mar 2026 | Viewed by 312 | Submission Open

Keywords: cancer vaccines; tumor antigens; tumor-associated antigens (TAAs); tumor-specific antigens (TSAs); subunit vaccines; peptide vaccines; mRNA vaccines; viral vector vaccines; adjuvants; antigen presentation; MHC class I and II upregulation; cancer immunotherapy; antibody– drug conjugates (ADCs); T cell engages; combination immunotherapy

Porcine Bacteria and Virus Vaccines

edited by Huixing Lin

submission deadline 25 Mar 2026 | Viewed by 368 | Submission Open

Keywords: Porcine; bacteria; virus; vaccine; diarrhea; dyspnea; adjuvant; attenuated vaccine; live vector vaccine; peptide vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines and Vaccine Preventable Diseases

edited by Elie Saade and Stefan Gravenstein

submission deadline 31 Mar 2026 | 8 articles | Viewed by 32897 | Submission Open

Keywords: vaccine-preventable diseases (VPDs); at-risk populations; older adults; nosocomial transmission; vaccine equity; immunization disparities; public health policy; social determinants of health; infection control; prophylactic and therapeutic vaccines

(This special issue belongs to the Section Vaccines and Public Health)

The Recent Development of Influenza Vaccine: 2nd Edition

edited by

Ramireddy Bommireddy

submission deadline 31 Mar 2026 | 8 articles | Viewed by 21746 | Submission Open

Keywords: influenza; older population; adjuvants; universal vaccine

(This special issue belongs to the Section Influenza Virus Vaccines)

Evaluating the Immune Response to RNA Vaccine

edited by

Ang Lin

and Huajun Zhao

submission deadline 31 Mar 2026 | 5 articles | Viewed by 17990 | Submission Open

Keywords: RNA vaccine; mechanism of action; immune regulation; innate immunity; adaptive vaccine response

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Mar 2026 | 7 articles | Viewed by 14511 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Animal Diseases: Immune Response and Vaccines

edited by

Verónica Martín

, José M. Rojas and

Noemí Sevilla

submission deadline 31 Mar 2026 | 8 articles | Viewed by 12514 | Submission Open

Keywords: immune responses; ruminants; vaccines; animal health

(This special issue belongs to the Section Veterinary Vaccines)

The Role of Vaccination on Public Health and Epidemiology

edited by

Antonio Rosa de Sousa Neto

and Daniela Reis Joaquim de Freitas

submission deadline 31 Mar 2026 | 4 articles | Viewed by 12396 | Submission Open

Keywords: vaccines; immunization; epidemiology; public health; vaccine-preventable diseases; pandemic preparedness; health equity

(This special issue belongs to the Section Vaccines and Public Health)

Herpes Simplex Virus Infection, Immunity, and Vaccine Development

edited by

Lbachir BenMohamed

and Swayam Prakash

submission deadline 31 Mar 2026 | 1 articles | Viewed by 8790 | Submission Open

Keywords: Herpes Simplex Virus (HSV); protection; humoral; and cellular immune mechanisms; vaccine development; HSV-1; HSV-2; immunization strategies

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Cancer Vaccines: 4th Edition

edited by

So Young Yoo

submission deadline 31 Mar 2026 | 2 articles | Viewed by 7445 | Submission Open

Keywords: cancer immunotherapy; therapeutic vaccine; tumor-associated antigens; neoantigens; adjuvant; tumor microenvironment; oncolytic viruses; immune checkpoint inhibitors

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Hepatitis Vaccines: Safety, Efficacy and Global Impact

edited by

Muhammad Atif Zahoor

submission deadline 31 Mar 2026 | 3 articles | Viewed by 7128 | Submission Open

Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges

(This special issue belongs to the Section Hepatitis Virus Vaccines)

From Knowledge to Action: Advances in Herpes Zoster Vaccine and Vaccination

edited by Giulia Silvestrini and

Manuela Chiavarini

submission deadline 31 Mar 2026 | 2 articles | Viewed by 6758 | Submission Open

Keywords: knowledge; attitudes; and practices regarding herpes zoster vaccination; vaccine hesitancy; vaccine uptake and inequality; efficacy; reactogenicity; and safety of herpes zoster vaccine; efficacy of different vaccines; the role of different type of herpes zoster vaccine in different target of population; active campaign

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Novel Adjuvants and Delivery Systems for Vaccines

edited by Christiane Chbib and

Mohammad N. Uddin

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4603 | Submission Open

Keywords: vaccines; drug development; adjuvants; nanoparticle

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Factors Affecting Influenza Vaccine Uptake

edited by

Adriana Pistol

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2612 | Submission Open

Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups

(This special issue belongs to the Section Influenza Virus Vaccines)

Vaccination Strategies and Population Immunity

edited by Matthew S. McGlone and Mian Jia

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1869 | Submission Open

Keywords: vaccination strategies; population immunity; health equity; vaccine access

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines and Immunotherapy for Inflammatory Disease

edited by

Pui-Ying Leong

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1768 | Submission Open

Keywords: vaccines; immunotherapy; inflammation; autoimmune disease; cytokines; immune modulation; chronic inflammatory diseases; immune response; vaccine development; translational immunology

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Influenza Virus Infections, Vaccines and Diagnosis

edited by

Roberta Antonia Diotti

, Isabel Pagani and Valeria Caputo

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1726 | Submission Open

Keywords: influenza; avian influenza; monoclonal antibodies; vaccine; therapy; infection

(This special issue belongs to the Section Influenza Virus Vaccines)

Epidemiology, Immunology, and Therapeutic Vaccines of Enteric Pathogens

edited by

Marina Valeria Mozgovoj

and

Ruchi Roy

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1577 | Submission Open

Keywords: enteric infectious diseases; vaccine development; intestinal immune response; mucosal immunology; therapeutic immunization strategies; epidemiology

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Development for Influenza Virus: 2nd Edition

edited by

Mingtao Zeng

and

Ganesh Yadaigiri

submission deadline 31 Mar 2026 | 2 articles | Viewed by 946 | Submission Open

Keywords: influenza vaccine; adjuvant; mRNA vaccine; novel vaccine technology; nanotechnology; immune response; animal; human

(This special issue belongs to the Section Influenza Virus Vaccines)

Cancer Vaccines and Immunotherapies

edited by

Subbaya Subramanian

submission deadline 31 Mar 2026 | Viewed by 518 | Submission Open

Keywords: cancer vaccines; tumor immunology; immunotherapy; mRNA vaccines; neoantigen-based therapies

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

HPV Vaccines and New Vaccination Schedules Implementation

edited by

Kirvis Torres-Poveda

, Aurelio Cruz-Valdez and Vicente Madrid-Marina

submission deadline 31 Mar 2026 | Viewed by 372 | Submission Open

Keywords: papillomavirus vaccines; vaccination schedule; HPV vaccine efficacy; vaccine uptake; implementation

(This special issue belongs to the Section Human Papillomavirus Vaccines)

SARS-CoV-2 Infection and COVID-19 Vaccination: Exploring Pathogenesis, Immune Response and Immunopathogenic Complications

edited by

Ronaldo B. Martins

, Tamara Rodrigues and Flavio Protasio Veras

submission deadline 31 Mar 2026 | Viewed by 364 | Submission Open

Keywords: SARS-CoV-2; COVID-19; vaccine adverse events; myocarditis and thrombosis; multisystem inflammatory syndrome; long COVID-19; immune response and autoimmunity; post-vaccine complications; therapeutic strategies; vaccine safety

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advancing Vaccine Strategies Against Viral Hemorrhagic Fevers: Innovation and Challenges

edited by

Massimo Spedicato

and

Stuart Dowall

submission deadline 31 Mar 2026 | Viewed by 356 | Submission Open

Keywords: viral hemorrhagic fevers; vaccines; Flaviviridae; Arenaviridae; Bunyaviridae; Filoviridae; Nairoviridae; Paramyxoviridae; Phenuiviridae

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Bio-Inspired Nanocarriers in Next-Generation Vaccines Against Bacterial and Viral Pathogens

edited by

Masamitsu Kanada

and

Shuhei Taguwa

submission deadline 31 Mar 2026 | Viewed by 343 | Submission Open

Keywords: lipid nanoparticles; liposomes; extracellular vesicles; nanovesicles; nanomedicine

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Developing Recombinant Vaccines and Immunotherapy Strategies for Emerging Viral Diseases

edited by

Emmanuel Datan

and

Athanasios Tsakris

submission deadline 31 Mar 2026 | Viewed by 338 | Submission Open

Keywords: emerging viral diseases; recombinant vaccines; immunotherapy; vaccine development; immune modulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Veterinary Antiparasitic Vaccines

edited by

Miriam Tendler

and Marília Sirianni dos Santos Almeida

submission deadline 31 Mar 2026 | Viewed by 319 | Submission Open

Keywords: anti-parasitic vaccines; veterinary vaccines; vaccine manufacturing platforms; helminths; One Health; zoonosis; Immunization Agenda 2030

(This special issue belongs to the Section Veterinary Vaccines)

Strategies and Innovations to Recover Post-Pandemic Losses in Routine Immunization Coverage

edited by Noha H. Farag

submission deadline 31 Mar 2026 | Viewed by 295 | Submission Open

Keywords: vaccines; immunization; pandemic; vaccine preventable diseases; interventions

(This special issue belongs to the Section Vaccines and Public Health)

Long-Term Immunity and Booster Strategies for COVID-19 Vaccines

edited by Alejo Erice and Ortiz De Lejarazu

submission deadline 31 Mar 2026 | Viewed by 184 | Submission Open

Keywords: SARS-CoV-2; mRNA vaccines; long-term immunity; immune imprinting; hybrid immunity; booster strategies

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Research on Immune Response and Vaccines: 2nd Edition

edited by James Galloway

submission deadline 30 Apr 2026 | 14 articles | Viewed by 66723 | Submission Open

Keywords: vaccines; immunogenicity; antigen recognition; adaptive immunity; cytokine response COVID-19; influenza; HPV; tuberculosis (BCG); malaria; HIV

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Apr 2026 | 14 articles | Viewed by 56532 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Human Papillomavirus Vaccine Against Cervical Cancer: New Usage Strategies and Coverage Issues

edited by

Luca Giannella

and

Andrea Ciavattini

submission deadline 30 Apr 2026 | 7 articles | Viewed by 38010 | Submission Open

Keywords: HPV vaccination coverage; HPV vaccination after conization; HPV vaccination in fertility-sparing treatment; male HPV vaccination HPV; vaccination after hysterectomy; tools for HPV vaccination implementation; HPV genotype in pre-invasive and invasive cervical pathology; HPV vaccination in vaginal pathology; HPV vaccination in vulvar pathology

(This special issue belongs to the Section Human Papillomavirus Vaccines)

COVID-19 Vaccination and Public Health: Addressing Global, Regional and Within-Country Inequalities

edited by

Dimitris Papamichail

and

Pietro Ferrara

submission deadline 30 Apr 2026 | 12 articles | Viewed by 27423 | Submission Open

Keywords: COVID-19 vaccine; population impact of COVID-19 vaccination; public health surveillance; health inequalities; access

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Production of Plant-Based Vaccines and Therapeutics

edited by Laurence K. Grill, John Howard and Kelvin Phiri

submission deadline 30 Apr 2026 | 2 articles | Viewed by 14463 | Submission Open

Keywords: plant-produced; viral-vectored; therapeutics; vaccines; tobacco mosaic virus (TMV)

Novel Vaccine Designs to Enhance the Engagement of Innate and Adaptive Immunity

edited by

Martin H. Bluth

and

Fangfeng Yuan

submission deadline 30 Apr 2026 | 6 articles | Viewed by 11875 | Submission Open

Keywords: vaccine; innate immunity; adaptive immunity; infectious disease; novel strategy; antigen delivery; protein engineering; adjuvants

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 30 Apr 2026 | 4 articles | Viewed by 8497 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccines and Immunization: Measles, Mumps, and Rubella

edited by Nobuhiko Okabe

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4194 | Submission Open

Keywords: measles; mumps; rubella; SSPE; hearing loss; CRS; immune mechanism; epidemiology; resurgence; life-course immunization

(This special issue belongs to the Section Epidemiology and Vaccination)

Advancing Health: Vaccination and Infectious Disease Prevention in Pregnant Women, Neonates, Infants, and Children

edited by

Eleni Vergadi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3491 | Submission Open

Keywords: infectious diseases; maternal immunization; pediatric infection control; immunization coverage; health equity; immunization strategies; vaccine safety

(This special issue belongs to the Section Vaccines and Public Health)

Arboviral Infections (Dengue, Chikungunya, Zika, and Other Mosquito-Borne Diseases): Immune Response and Vaccine Development

edited by

Bo Peng

and Xiaolu Shi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1973 | Submission Open

Keywords: arbovirus; dengue virus; chikungunya virus; Zika virus; mosquito-borne disease; immune response; cross-immunity; antibody-dependent enhancement (ADE); vaccine development; immunopathology

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

BCG Vaccine and Beyond: Innovations in Tuberculosis Vaccination and Inflammation-Related Disease Prevention

edited by

Xiao-Yong Fan

and

Zhi-Dong Hu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1886 | Submission Open

Keywords: tuberculosis; vaccine; vaccination; immune response; adjuvant; T-cell; immune memory; adaptive immunity; innate immune memory; correlates of protection

(This special issue belongs to the Section Vaccines against Infectious Diseases)

New Challenges in Vaccines and Vaccination: A Public Health Perspective

edited by

Marcello Guido

and

Antonella Zizza

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1813 | Submission Open

Keywords: vaccine effectiveness/efficacy; vaccination strategies; tailored approaches for different populations; public health

(This special issue belongs to the Section Vaccines and Public Health)

Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1700 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1560 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

New Horizons in the Fight Against Vector-Borne Diseases and Parasitic Infestations: From Basic Research to Applied Studies in Vaccines

edited by