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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Analysis and Risk Assessment of Agrochemicals in Food and Environment

edited by Shanshan Di and

Zhiyuan Meng

submission deadline 30 Nov 2026 | Viewed by 233 | Submission Open

Keywords: agrochemicals; food safety; environmental safety assessment; environmental fate; non-target organism toxicity; risk assessment model

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Assessing the Ecological Risk of Chemical Pollution: Integrating Emerging Methodologies, Alternative Models and Mechanistic Approaches Across Diverse Ecosystems

edited by

Jerusa Maria Oliveira

and Mariella Bontempo Freitas

submission deadline 30 Nov 2026 | Viewed by 134 | Submission Open

Keywords: ecological risk assessment; emerging contaminants; oxidative stress and redox biology; New Approach Methodologies (NAMs); alternative animal models; ecotoxicology; chemical mixtures

(This special issue belongs to the Section Ecotoxicology)

Novel Methods and Applications in Zebrafish as a Model for Mixture Toxicity

edited by

Lisa Truong

submission deadline 1 Dec 2026 | Viewed by 211 | Submission Open

Keywords: zebrafish; chemical mixture toxicity; environmental mixture exposures; synergism, antagonism, and additivity; new approach methodologies (NAMs)

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Selected Papers from the 3rd International Online Conference on Toxics (IOCTO2026)

edited by

Emilio Benfenati

Gunnar Toft

and

Yankai Xia

submission deadline 4 Dec 2026 | Viewed by 375 | Submission Open

Keywords: ecotoxicology; ecosystem health; exposure routes; emerging contaminants; innovating toxicology; comparative toxicology; one health; environmental health

Pollutants in Soil and Groundwater, Effects and Strategies for Comprehensive Risk Assessment

edited by

Zhongkang Yang

, Wenhan Cheng, Zhuding Chu and

Ruijuan Qu

submission deadline 10 Dec 2026 | 5 articles | Viewed by 5308 | Submission Open

Keywords: soil and groundwater pollution; risk assessment; ecological and human health impacts; remediation strategies; emerging pollutants; environmental monitoring

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Halogenated and Heterocyclic Derivatives of Polycyclic Aromatic Compounds (PACs): Bridging the Gaps in Occurrence, Exposure, and Toxicological Risk

edited by Philippe J. Thomas and

Gregg Tomy

submission deadline 15 Dec 2026 | Viewed by 410 | Submission Open

Keywords: polycyclic aromatic compounds (PACs); emerging contaminants; non-target screening; persistent organic pollutants (POPs); toxicology; bioaccumulation; source apportionment

(This special issue belongs to the Section Emerging Contaminants)

Analytical Methods for Trace Elements in Human Biofluids

edited by

Lucas Schmidt

submission deadline 15 Dec 2026 | Viewed by 134 | Submission Open

Keywords: trace element analysis; Human biofluid; ICP-MS; atomic spectrometry; biomonitoring; elemental speciation; metals

(This special issue belongs to the Section Novel Methods in Toxicology Research)

The Molecular Mechanisms of Heavy Metal Induced Neurotoxicity

edited by

Pan Chen

submission deadline 18 Dec 2026 | Viewed by 217 | Submission Open

Keywords: neurotoxicity; heavy metals; neurodegeneration; oxidative stress; mitochondrial dysfunction

(This special issue belongs to the Section Neurotoxicity)

Environmental Toxicants in Human Health: Oxidative Stress, Metabolism and Toxicity

edited by

David A. Lawrence

and Michael Lynes

submission deadline 20 Dec 2026 | 2 articles | Viewed by 1819 | Submission Open

Keywords: environmental toxicants; immune cells; inflammation; oxidative stress; developmental and aging; autoimmunity

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Old Issues and New Challenges in Elucidating Fatal and Non-Fatal Intoxications: The Integrated Role of Forensic Toxicology and Pathology

edited by

Maria Pieri

and

Pascale Basilicata

submission deadline 20 Dec 2026 | Viewed by 164 | Submission Open

Keywords: forensic toxicology; forensic pathology; intoxications; AI tools; pediatric/occupational exposure

Toxic Effects of Emerging Pollutants on Aquatic Organisms and Human

edited by

Christopher Martyniuk

submission deadline 23 Dec 2026 | 3 articles | Viewed by 4168 | Submission Open

Keywords: emerging contaminants; aquatics; human; molecular; biochemical; behavioral

(This special issue belongs to the Section Emerging Contaminants)

Air Pollution and Health: From Exposure Assessment to Biological Mechanisms and Risk Prevention

edited by

Ting Wang

, Tingting Ku and

Jia Xu

submission deadline 25 Dec 2026 | 1 articles | Viewed by 738 | Submission Open

Keywords: air pollution; exposure assessment; epidemiological study; biological mechanism; emerging pollutants; health prevention

(This special issue belongs to the Section Air Pollution and Health)

Constructed Wetlands for Emerging Pollutants: Fate, Ecotoxicity, and Greenhouse Gas Emissions

edited by Haiming Wu and

Chunzhen Fan

submission deadline 25 Dec 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: constructed wetlands; emerging pollutants; microplastics; perfluorooctane sulphonate; antibiotics; migration and conversion; ecotoxicity; greenhouse gas

(This special issue belongs to the Section Emerging Contaminants)

Functional Microbial Communities in Soil Health and Pollution Mitigation

edited by

Qichun Zhang

submission deadline 30 Dec 2026 | 1 articles | Viewed by 915 | Submission Open

Keywords: functional microbial communities; soil health; pollution mitigation; microbial ecology; soil microbial diversity; ecological remediation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Emerging Environmental Pollutants and Their Impact on Human Health

edited by Chien Yu Lin,

Yu-Wei Fang

and

Ching-Chung Hsiao

submission deadline 31 Dec 2026 | 8 articles | Viewed by 22152 | Submission Open

Keywords: emerging contaminants; cohort studies; epigenetics; oxidative stress; cardiovascular disease; endocrine disruptors; monoterpenes; glyphosate; human health

(This special issue belongs to the Section Emerging Contaminants)

Effects of Air Pollutants on Cardiorespiratory Health

edited by Weihong Chen,

Shaowei Wu

and

Yun Zhou

submission deadline 31 Dec 2026 | 4 articles | Viewed by 14014 | Submission Open

Keywords: air pollutants; cardiorespiratory toxicity; cardio-pulmonary function; air pollution exposure assessment; chronic obstructive pulmonary disease; cardiovascular disease; airway inflammation; pulmonary fibrosis

(This special issue belongs to the Section Air Pollution and Health)

Heavy Metals and Emerging Contaminants in Aquatic and Soil Environments: Migration, Transformation, Ecological Risks, and Remediation

edited by

Xiaoshuai Hang

, Yingang Xue and

Jian Cui

submission deadline 31 Dec 2026 | 10 articles | Viewed by 11071 | Submission Open

Keywords: heavy metal; air; soils; water; sediment; environmental behavior; human health; migration and transformation; pollution remediation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Multi-Media Exposure to Emerging Contaminants and Health Effects Across Physiological Systems: Exposure Pathways, Risk Assessment and Public Health Implications

edited by

Guanghui Dong

and

Lizi Lin

submission deadline 31 Dec 2026 | 7 articles | Viewed by 8657 | Submission Open

Keywords: emerging contaminants; multi-media exposure; exposure pathways; health effects; risk assessment; toxicity mechanisms; public health implications

(This special issue belongs to the Section Emerging Contaminants)

Emerging Methodologies in Toxicology for Environmental Safety Assessment

edited by

Melissa Faria

Juliette Bedrossiantz

and

Marcelino Miguel Guedes de Jesus Oliveira

submission deadline 31 Dec 2026 | 2 articles | Viewed by 5816 | Submission Open

Keywords: toxicology; chemical safety; emerging contaminants; integrated approaches; predictive modeling; new methodology approaches; high-throughput screening; adverse-outcome pathways; risk assessment; One Health

Degradation and Remediation of Environmental Pollutants

edited by

Osamah J. Al-sareji

Ruqayah Ali Grmasha

and

Raed A Al-Juboori

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4536 | Submission Open

Keywords: water and wastewater treatment; degradation; pharmaceutical removal; reusability; performance improvements; chemical treatment; polycyclic aromatic hydrocarbons; emerging contaminants; activated carbon; physical treatment

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Ecotoxicology of Emerging Contaminants in the Water Environment

edited by Roberta Bettinetti and Ginevra Boldrocchi

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3478 | Submission Open

Keywords: ecotoxicology; marine pollution; elasmobranchs; zooplankton; trace metals; freshwater; contaminants; plastic pollution; emerging contaminants; legacy contaminants

Emerging Contaminants in Soil and Freshwater Systems: Ecotoxicological Insights from Individual to Community-Level Studies or Across Biological Scales

edited by

Ana Belén Muñiz

Sara Villa

and

Patricia Almendros

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3303 | Submission Open

Keywords: aquatic invertebrate; soil invertebrates; anthropogenic impact; ecotoxicology

(This special issue belongs to the Section Ecotoxicology)

Classical Environmental Process Modeling, Interpretable Machine Learning, and Their Integrative Innovations—Targeting Atmospheric, Water, and Soil Pollution

edited by

and

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2954 | Submission Open

Keywords: environmental models; environmental simulation; environmental management; machine learning; deep learning; source apportionment; atmosphere; soil; water

Emerging Contaminants in a Changing World: Implications for Human Health

edited by

Andrea Moscato

and

Maria Fiore

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2588 | Submission Open

Keywords: emerging contaminants, PFAS, TFA, micro- and nano-plastics; environmental exposure; risk assessment; environmental epidemiology; toxicological effects

(This special issue belongs to the Section Emerging Contaminants)

Health Risk Assessment of Emerging Pollutants—an Integration of Exposure Estimation and Mechanism-Based Toxicity Study

edited by

Yungang Liu

, Haiming Xu and Ming Shi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2494 | Submission Open

Keywords: persistent organic pollutants; endocrine disruptors; environmental antibiotics; microplastics; metabolically-modulated/activated toxicity; neuro-behavioral toxicity; endocrinal disruption

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Exposure and Effects of Endocrine Disrupting Chemicals

edited by Huifeng Yue

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2093 | Submission Open

Keywords: endocrine-disrupting chemicals (EDCs); bisphenol A (BPA); per- and polyfluoroalkyl substances (PFAS); analogs; toxicological mechanisms; environmental health; emerging environmental pollutants; perinatal or maternal exposure; offspring

(This special issue belongs to the Section Emerging Contaminants)

Environmental Fate, Toxicity, Risk Assessment and Remediation of Contaminants Associated with Mining and Industrial Activities

edited by

Shan Liu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1342 | Submission Open

Keywords: environmental fate; contaminant transport and transformation; ecotoxicity; human health risk assessment; bioavailability; mixed contamination; environmental remediation; pollution control; mining activities; industrial activities; heavy metal; soil pollution; machine learning; emerging contaminants; trace elements

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Novel Remediation Strategies for Soil Pollution—2nd Edition

edited by Jiaqi Shi and Tingting Fan

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1322 | Submission Open

Keywords: soil remediation; advanced oxidative process; soil risk assessment; bioremediation; combined remediation of soil and groundwater; development of innovative remediation material

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Advancements in Photocatalytic Oxidation for the Effective Removal of Toxic Contaminants in Water and Wastewater

edited by

Zhongliao Wang

and

Zhen Li

submission deadline 31 Dec 2026 | Viewed by 488 | Submission Open

Keywords: photocatalytic oxidation; toxic contaminants; water treatment; advanced oxidation processes; environmental remediation; reactive oxygen species; degradation mechanisms

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Exposure to Emerging Contaminants and Human Health Risks

edited by

Zongrui Li

and Lin Tao

submission deadline 31 Dec 2026 | 1 articles | Viewed by 406 | Submission Open

Keywords: emerging contaminants; environmental exposure; bioaccumulation; environmental risk assessment; human health effects

(This special issue belongs to the Section Emerging Contaminants)

Advancing Cosmetic Safety Science: Approaches for Skin Compatibility and Risk Assessment

edited by

Anca Maria Juncan

Luca-Liviu Rus

and

Adriana Ciurba

submission deadline 31 Dec 2026 | Viewed by 388 | Submission Open

Keywords: cosmetic ingredients; cosmetic products; toxicological evaluation; skin compatibility; safety assessment; risk assessment

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Analytical Methods and Health Implications of Microplastic Contamination in Food Products

edited by

Kornelia Kadac-Czapska

and

Małgorzata Grembecka

submission deadline 31 Dec 2026 | Viewed by 352 | Submission Open

Keywords: microplastic contamination; food safety; polymers; plastics; food processing and packaging; pollutant adsorption; human exposure assessment; analytical detection methods; spectroscopic identification

(This special issue belongs to the Section Emerging Contaminants)

Sustainable Remediation Strategies for Metal-Contaminated Soil and Sediments

edited by

Catherine Mulligan

submission deadline 31 Dec 2026 | Viewed by 341 | Submission Open

Keywords: sustainability; green remediation; metals; soil; physical treatment; chemical treatment; phytoremediation; risk assessment; site restoration; sediments

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Feature Papers in Environmental Epidemiology—2nd Edition

edited by

Chongjian Wang

and

Peng Lu

submission deadline 31 Dec 2026 | Viewed by 303 | Submission Open

Keywords: environmental epidemiology; environmental exposure; health effects; air pollution; emerging contaminants; vulnerable populations; methodological innovations

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Pharmaceuticals in Aquatic Environments: Occurrence, Fate, Ecotoxicological Effects and Risk Assessment

edited by

Marcelo Pedrosa Pedrosa Gomes

submission deadline 31 Dec 2026 | Viewed by 221 | Submission Open

Keywords: pharmaceuticals; emerging contaminants; aquatic environments; environmental monitoring; wastewater treatment plants; ecotoxicology; environmental risk assessment; transformation products; pharmaceutical mixtures; antimicrobial resistance

(This special issue belongs to the Section Emerging Contaminants)

Toxicant-Induced Lung Injury: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Irfan Rahman

and

Narasaiah Kolliputi

submission deadline 31 Dec 2026 | Viewed by 136 | Submission Open

Keywords: air pollution; inhalation toxicology; environmental exposure; oxidative stress; precision medicine; inflammation; biomarkers; multi-omics; COPD; lung injury; ARDS; IPF; TRPV4

(This special issue belongs to the Section Air Pollution and Health)

Insect Responses to Environmental Stressors

edited by

Yao Tan

and Jiale Yang

submission deadline 31 Dec 2026 | Viewed by 123 | Submission Open

Keywords: insect response; environmental stressors; insect adaptability; insecticide resistance; cold hardiness; chemicals; pesticides; ecotoxicology; drugs toxicity; neurotoxicity; RNAi; RNA-based biological pesticides

(This special issue belongs to the Section Ecotoxicology)

Detection of Air Pollutants—2nd Edition

edited by Zhiyuan Li

submission deadline 31 Dec 2026 | Viewed by 110 | Submission Open

Keywords: air pollution; atmospheric chemistry; stationary reference instruments; smart low-cost sensors; remote sensing of air pollution; laboratory experimental studies; LiDAR system

(This special issue belongs to the Section Air Pollution and Health)

Aerosol Toxicity in a Changing World: Sources, Atmospheric Transformations, Health Impacts, and Mitigation

edited by Judith C. Chow, Kin Fai Ho,

Jianjun Li

, Xinyi Niu and

Siwatt Pongpiachan

submission deadline 31 Dec 2026 | Viewed by 55 | Submission Open

Keywords: aerosol toxicity; particulate matter; oxidative potential; ultrafine particles; atmospheric aging; bioaerosols; exposure assessment; computational toxicology; health risk assessment; mitigation strategies

Interventions, Practices, and Policies to Reduce Particulate Matter Air Pollution Exposure and Health Outcomes

edited by

Douglas Brugge

and Shir Ginzburg

submission deadline 15 Jan 2027 | 3 articles | Viewed by 7557 | Submission Open

Keywords: exposure reduction; health outcomes; interventions; particulate matter; randomized trials

(This special issue belongs to the Section Air Pollution and Health)

Environmental and Reproductive Epidemiology: Focus on Air Pollution and Associated Contaminants

edited by Junling Wang,

Yankai Xia

Bin Luo

and Haitao Ma

submission deadline 15 Jan 2027 | 2 articles | Viewed by 2868 | Submission Open

Keywords: air pollution; heavy metals; polycyclic aromatic hydrocarbons; environmental exposure; repro-ductive epidemiology; particulate matter; endocrine-disrupting chemicals

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Association Between Environmental Pollutants Exposures and Chronic Disease

edited by

Fei Wang

submission deadline 15 Jan 2027 | 1 articles | Viewed by 1562 | Submission Open

Keywords: environmental pollutant and exposure effects; chronic diseases; epidemiological effects; induced health effects; public health; toxic effects; biological mechanism

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Human Exposure Toxicology and Health Risks of Environmental Rare Earth Elements

edited by Lihua Huang and

Daochuan Li

submission deadline 25 Jan 2027 | Viewed by 37 | Submission Open

Keywords: rare earth elements; toxicity; occupational exposure; risk assessment

(This special issue belongs to the Section Emerging Contaminants)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and

Inmaculada Varó

submission deadline 29 Jan 2027 | 3 articles | Viewed by 6113 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Air Pollutants: Sources, Characteristics, Environmental Impacts and Human Health Risks

edited by

Xiaotong Jiang

and Yinxiao Zhang

submission deadline 31 Jan 2027 | 3 articles | Viewed by 1327 | Submission Open

Keywords: air pollution; source apportionment; air quality; PM2.5; atmospheric chemistry; biomass burning; data-driven analysis; toxicology; human health effects; environmental impacts; ozone

(This special issue belongs to the Section Air Pollution and Health)

Potentially Toxic Elements Pollution in Urban and Suburban Environments, 3rd Edition

edited by

Ilaria Guagliardi

submission deadline 31 Jan 2027 | Viewed by 350 | Submission Open

Keywords: potentially toxic elements (PTEs); environmental geochemistry; soil, sediment, water, air pollution; geogenic and anthropogenic pollutant input; bioavailability; PTE mapping; spatial data analysis

Safety Assessment of Toxic Substances in Food Contact Materials

edited by Emma Di Consiglio

submission deadline 31 Jan 2027 | Viewed by 347 | Submission Open

Keywords: toxicology; next-generation risk assessment; new approach methodologies (NAM); human health; food contact materials; environmental contaminants; toxicokinetics

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

The Carcinogenicity and Toxicology of Chemical Mixtures Using New Approach Methodologies

edited by Yansen Bai and Hao Wang

submission deadline 31 Jan 2027 | Viewed by 110 | Submission Open

Keywords: toxicology; epidemiology; omics; carcinogenicity; chemical mixtures; multi-exposure analysis method; epigenetics; hormesis

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Health Risk Assessment of Exposure to Emerging Contaminants—2nd Edition

edited by Suzhen Cao

submission deadline 31 Jan 2027 | Viewed by 91 | Submission Open

Keywords: health risk assessment; emerging contaminants; microplastics; endocrine disruptors; persistent organic pollutant; antibiotics; exposure pathways; exposure scenarios; exposure factors; toxicity mechanisms; epidemiological research; toxicological studies; risk mitigation strategies

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Adsorption and Photocatalysis of Organic Pollutants: Latest Advances and Prospects

edited by Yufeng Jiang

submission deadline 5 Feb 2027 | 2 articles | Viewed by 2409 | Submission Open

Keywords: emerging contaminants; adsorption; photocatalysis; soil and water; environmental remediation; degradation pathways; eco-toxicity

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

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