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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Occupational Exposure to Heavy Metals in Environmentally Vulnerable Areas

edited by

Jingbo Zhao

and

Antonio Peña-Fernández

submission deadline 20 Nov 2026 | 4 articles | Viewed by 9549 | Submission Open

Keywords: heavy metal; occupational exposure; health risk; exposure route; source identification; toxic mechanisms; pollution characteristics

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Internal Exposure to Microplastics: Kinetics, Mixtures and Markers

edited by Umberto Cornelli

submission deadline 20 Nov 2026 | Viewed by 143 | Submission Open

Keywords: microplastics; exposure; biomarkers; polymer mixtures; internal kinetics; analytical standardization

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Environmental Drivers of Chronic Disease: From Population Landscapes to Molecular Mechanisms

edited by Jian Hou, Weidong Wu and

Yanjun Guo

submission deadline 22 Nov 2026 | 2 articles | Viewed by 2158 | Submission Open

Keywords: environmental epidemiology; chronic non-communicable diseases; gene– environment interaction; gut microbiota; oxidative stress; human health

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Atmospheric Emissions, Exposure, Monitoring and Prediction

edited by

Qingchun Guo

Chong Wei

and Jiamao Zhou

submission deadline 23 Nov 2026 | 2 articles | Viewed by 1180 | Submission Open

Keywords: high-resolution emission; human exposure; monitoring and data Integration; air quality prediction and forecasting; policy; artificial intelligence; deep learning

(This special issue belongs to the Section Air Pollution and Health)

Advances in Water, Air and Soil Pollution Monitoring, Modeling and Restoration, 2nd Edition

edited by

Alina Bărbulescu

Lucica Barbes

and

Cristian Ștefan Dumitriu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3632 | Submission Open

Keywords: environmental impact of pollution and risk assessment; statistical methods and mathematical models for environmental pollution; waste treatment engineering and ecotoxicity evaluation; impact of pollution on human health; engineering solution for pollution reduction (e.g.; eco-friendly materials)

Analysis of Environmental Distribution, Mechanisms of Effects, and Risk of Pollutants Driven by New Technologies

edited by

Zhen-Guang Yan

, Yizhang Zhang and

Yifan Zheng

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2472 | Submission Open

Keywords: artificial intelligence; machine learning; environmental DNA; emerging pollutants; optimal control pollutants; environmental omics; risk assessment; risk management

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Environmental Risks, Migration and Remediation of Legacy and Emerging Toxicants

edited by Meiling Xu, Jia Li and Qunqun Liu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1479 | Submission Open

Keywords: legacy toxicants; emerging contaminants; environmental behaviour; environmental risks; remediation technology; soil sediments; water ecosystems

(This special issue belongs to the Section Ecotoxicology)

Effects of Acute Exposure to Toxicants on Oxidative Stress in Aquatic Organisms, 2nd Edition

edited by

Luís Félix

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1400 | Submission Open

Keywords: toxicology; oxidative stress; antioxidant; biomarkers; reactive oxygen species; oxidative damage; redox homeostasis

(This special issue belongs to the Section Ecotoxicology)

Persistent Organic Pollutants (POPs) Hazards and Challenges

edited by

Yiting Luo

Rongkui Su

and Xiancheng Ma

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1300 | Submission Open

Keywords: persistent Organic Pollutants (POPs); bioaccumulation; biomagnification; human health impacts; ecological risks; detection technologies; mitigation strategies; stockholm Convention; endocrine disruption; long-range transport

(This special issue belongs to the Section Emerging Contaminants)

Safe Utilization and Ecological Restoration of Heavy Metal Polluted Farmland—2nd Edition

edited by

Bin Guo

and

Ying Feng

submission deadline 30 Nov 2026 | Viewed by 270 | Submission Open

Keywords: heavy metal; environment; phytoremediation; utilization; ecological restoration

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Phthalates: Environmental Distribution, Human Exposure, and Health Risks

edited by Melissa Rodrigues Mariana,

Margarida Ferreira Lorigo

and

Elisa Cairrao

submission deadline 30 Nov 2026 | Viewed by 215 | Submission Open

Keywords: phthalates; environmental contamination; human exposure; endocrine disrupting chemicals; biomonitoring; toxicological mechanisms; health risk assessment

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Advanced Analysis and Risk Assessment of Agrochemicals in Food and Environment

edited by Shanshan Di and

Zhiyuan Meng

submission deadline 30 Nov 2026 | Viewed by 179 | Submission Open

Keywords: agrochemicals; food safety; environmental safety assessment; environmental fate; non-target organism toxicity; risk assessment model

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Human Exposure and Health Risk Assessment of Emerging Contaminants

edited by

Anna Laura Iamiceli

and

Chiara Laura Battistelli

submission deadline 30 Nov 2026 | Viewed by 169 | Submission Open

Keywords: emerging contaminants; micro- and nanoplastics; per- and polyfluoroalkyl substances (PFAS); suspect and untarget screening; new approach methodologies (NAMs); in silico toxicology; human health risk assessment; human biomonitoring; One Health approach; exposome; human exposure

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Assessing the Ecological Risk of Chemical Pollution: Integrating Emerging Methodologies, Alternative Models and Mechanistic Approaches Across Diverse Ecosystems

edited by

Jerusa Maria Oliveira

and Mariella Bontempo Freitas

submission deadline 30 Nov 2026 | Viewed by 84 | Submission Open

Keywords: ecological risk assessment; emerging contaminants; oxidative stress and redox biology; New Approach Methodologies (NAMs); alternative animal models; ecotoxicology; chemical mixtures

(This special issue belongs to the Section Ecotoxicology)

Novel Methods and Applications in Zebrafish as a Model for Mixture Toxicity

edited by

Lisa Truong

submission deadline 1 Dec 2026 | Viewed by 111 | Submission Open

Keywords: zebrafish; chemical mixture toxicity; environmental mixture exposures; synergism; antagonism; and additivity; new approach methodologies (NAMs)

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Selected Papers from the 3rd International Online Conference on Toxics (IOCTO2026)

edited by

Emilio Benfenati

Gunnar Toft

and

Yankai Xia

submission deadline 4 Dec 2026 | Viewed by 264 | Submission Open

Keywords: ecotoxicology; ecosystem health; exposure routes; emerging contaminants; innovating toxicology; comparative toxicology; one health; environmental health

Pollutants in Soil and Groundwater, Effects and Strategies for Comprehensive Risk Assessment

edited by

Zhongkang Yang

, Wenhan Cheng, Zhuding Chu and

Ruijuan Qu

submission deadline 10 Dec 2026 | 4 articles | Viewed by 4290 | Submission Open

Keywords: soil and groundwater pollution; risk assessment; ecological and human health impacts; remediation strategies; emerging pollutants; environmental monitoring

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Analytical Methods for Trace Elements in Human Biofluids

edited by

Lucas Schmidt

submission deadline 15 Dec 2026 | Viewed by 11 | Submission Open

Keywords: trace element analysis; Human biofluid; ICP-MS; atomic spectrometry; biomonitoring; elemental speciation; metals

(This special issue belongs to the Section Novel Methods in Toxicology Research)

The Molecular Mechanisms of Heavy Metal Induced Neurotoxicity

edited by

Pan Chen

submission deadline 18 Dec 2026 | Viewed by 114 | Submission Open

Keywords: neurotoxicity; heavy metals; neurodegeneration; oxidative stress; mitochondrial dysfunction

(This special issue belongs to the Section Neurotoxicity)

Old Issues and New Challenges in Elucidating Fatal and Non-Fatal Intoxications: The Integrated Role of Forensic Toxicology and Pathology

edited by

Maria Pieri

and

Pascale Basilicata

submission deadline 20 Dec 2026 | Viewed by 84 | Submission Open

Keywords: forensic toxicology; forensic pathology; intoxications; AI tools; pediatric/occupational exposure

Air Pollution and Health: From Exposure Assessment to Biological Mechanisms and Risk Prevention

edited by

Ting Wang

, Tingting Ku and

Jia Xu

submission deadline 25 Dec 2026 | Viewed by 195 | Submission Open

Keywords: air pollution; exposure assessment; epidemiological study; biological mechanism; emerging pollutants; health prevention

(This special issue belongs to the Section Air Pollution and Health)

Constructed Wetlands for Emerging Pollutants: Fate, Ecotoxicity, and Greenhouse Gas Emissions

edited by Haiming Wu and

Chunzhen Fan

submission deadline 25 Dec 2026 | Viewed by 87 | Submission Open

Keywords: constructed wetlands; emerging pollutants; microplastics; perfluorooctane sulphonate; antibiotics; migration and conversion; ecotoxicity; greenhouse gas

(This special issue belongs to the Section Emerging Contaminants)

Functional Microbial Communities in Soil Health and Pollution Mitigation

edited by

Qichun Zhang

submission deadline 30 Dec 2026 | Viewed by 250 | Submission Open

Keywords: functional microbial communities; soil health; pollution mitigation; microbial ecology; soil microbial diversity; ecological remediation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Effects of Air Pollutants on Cardiorespiratory Health

edited by Weihong Chen,

Shaowei Wu

and

Yun Zhou

submission deadline 31 Dec 2026 | 4 articles | Viewed by 12390 | Submission Open

Keywords: air pollutants; cardiorespiratory toxicity; cardio-pulmonary function; air pollution exposure assessment; chronic obstructive pulmonary disease; cardiovascular disease; airway inflammation; pulmonary fibrosis

(This special issue belongs to the Section Air Pollution and Health)

Heavy Metals and Emerging Contaminants in Aquatic and Soil Environments: Migration, Transformation, Ecological Risks, and Remediation

edited by

Xiaoshuai Hang

, Yingang Xue and

Jian Cui

submission deadline 31 Dec 2026 | 8 articles | Viewed by 7857 | Submission Open

Keywords: heavy metal; air; soils; water; sediment; environmental behavior; human health; migration and transformation; pollution remediation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Ecotoxicology of Emerging Contaminants in the Water Environment

edited by Roberta Bettinetti and Ginevra Boldrocchi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2139 | Submission Open

Keywords: ecotoxicology; marine pollution; elasmobranchs; zooplankton; trace metals; freshwater; contaminants; plastic pollution; emerging contaminants; legacy contaminants

Classical Environmental Process Modeling, Interpretable Machine Learning, and Their Integrative Innovations—Targeting Atmospheric, Water, and Soil Pollution

edited by

and

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2077 | Submission Open

Keywords: environmental models; environmental simulation; environmental management; machine learning; deep learning; source apportionment; atmosphere; soil; water

Emerging Contaminants in a Changing World: Implications for Human Health

edited by

Andrea Moscato

and

Maria Fiore

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1148 | Submission Open

Keywords: emerging contaminants; PFAS; TFA; micro- and nano-plastics; environmental exposure; risk assessment; environmental epidemiology; toxicological effects

(This special issue belongs to the Section Emerging Contaminants)

Advancements in Photocatalytic Oxidation for the Effective Removal of Toxic Contaminants in Water and Wastewater

edited by

Zhongliao Wang

and

Zhen Li

submission deadline 31 Dec 2026 | Viewed by 449 | Submission Open

Keywords: photocatalytic oxidation; toxic contaminants; water treatment; advanced oxidation processes; environmental remediation; reactive oxygen species; degradation mechanisms

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Novel Remediation Strategies for Soil Pollution—2nd Edition

edited by Jiaqi Shi and Tingting Fan

submission deadline 31 Dec 2026 | 1 articles | Viewed by 418 | Submission Open

Keywords: soil remediation; advanced oxidative process; soil risk assessment; bioremediation; combined remediation of soil and groundwater; development of innovative remediation material

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Advancing Cosmetic Safety Science: Approaches for Skin Compatibility and Risk Assessment

edited by

Anca Maria Juncan

Luca-Liviu Rus

and

Adriana Ciurba

submission deadline 31 Dec 2026 | Viewed by 330 | Submission Open

Keywords: cosmetic ingredients; cosmetic products; toxicological evaluation; skin compatibility; safety assessment; risk assessment

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Exposure and Effects of Endocrine Disrupting Chemicals

edited by Huifeng Yue

submission deadline 31 Dec 2026 | Viewed by 309 | Submission Open

Keywords: endocrine-disrupting chemicals (EDCs); bisphenol A (BPA); per- and polyfluoroalkyl substances (PFAS); analogs; toxicological mechanisms; environmental health; emerging environmental pollutants; perinatal or maternal exposure; offspring

(This special issue belongs to the Section Emerging Contaminants)

Sustainable Remediation Strategies for Metal-Contaminated Soil and Sediments

edited by

Catherine Mulligan

submission deadline 31 Dec 2026 | Viewed by 294 | Submission Open

Keywords: sustainability; green remediation; metals; soil; physical treatment; chemical treatment; phytoremediation; risk assessment; site restoration; sediments

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Feature Papers in Environmental Epidemiology—2nd Edition

edited by

Chongjian Wang

and

Peng Lu

submission deadline 31 Dec 2026 | Viewed by 258 | Submission Open

Keywords: environmental epidemiology; environmental exposure; health effects; air pollution; emerging contaminants; vulnerable populations; methodological innovations

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Pharmaceuticals in Aquatic Environments: Occurrence, Fate, Ecotoxicological Effects and Risk Assessment

edited by

Marcelo Pedrosa Pedrosa Gomes

submission deadline 31 Dec 2026 | Viewed by 125 | Submission Open

Keywords: pharmaceuticals; emerging contaminants; aquatic environments; environmental monitoring; wastewater treatment plants; ecotoxicology; environmental risk assessment; transformation products; pharmaceutical mixtures; antimicrobial resistance

(This special issue belongs to the Section Emerging Contaminants)

Exposure to Emerging Contaminants and Human Health Risks

edited by

Zongrui Li

and Lin Tao

submission deadline 31 Dec 2026 | Viewed by 104 | Submission Open

Keywords: emerging contaminants; environmental exposure; bioaccumulation; environmental risk assessment; human health effects

(This special issue belongs to the Section Emerging Contaminants)

Environmental Fate, Toxicity, Risk Assessment and Remediation of Contaminants Associated with Mining and Industrial Activities

edited by

Shan Liu

submission deadline 31 Dec 2026 | Viewed by 93 | Submission Open

Keywords: environmental fate; contaminant transport and transformation; ecotoxicity; human health risk assessment; bioavailability; mixed contamination; environmental remediation; pollution control; mining activities; industrial activities; heavy metal; soil pollution; machine learning; emerging contaminants; trace elements

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxicant-Induced Lung Injury: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Irfan Rahman

and

Narasaiah Kolliputi

submission deadline 31 Dec 2026 | Viewed by 65 | Submission Open

Keywords: air pollution; inhalation toxicology; environmental exposure; oxidative stress; precision medicine; inflammation; biomarkers; multi-omics; COPD; lung injury; ARDS; IPF; TRPV4

(This special issue belongs to the Section Air Pollution and Health)

Insect Responses to Environmental Stressors

edited by

Yao Tan

and Jiale Yang

submission deadline 31 Dec 2026 | Viewed by 53 | Submission Open

Keywords: insect response; environmental stressors; insect adaptability; insecticide resistance; cold hardiness; chemicals; pesticides; ecotoxicology; drugs toxicity; neurotoxicity; RNAi; RNA-based biological pesticides

(This special issue belongs to the Section Ecotoxicology)

Detection of Air Pollutants—2nd Edition

edited by Zhiyuan Li

submission deadline 31 Dec 2026 | Viewed by 34 | Submission Open

Keywords: air pollution; atmospheric chemistry; stationary reference instruments; smart low-cost sensors; remote sensing of air pollution; laboratory experimental studies; LiDAR system

(This special issue belongs to the Section Air Pollution and Health)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and

Inmaculada Varó

submission deadline 29 Jan 2027 | 1 articles | Viewed by 4320 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Potentially Toxic Elements Pollution in Urban and Suburban Environments, 3rd Edition

edited by

Ilaria Guagliardi

submission deadline 31 Jan 2027 | Viewed by 223 | Submission Open

Keywords: potentially toxic elements (PTEs); environmental geochemistry; soil; sediment; water; air pollution; geogenic and anthropogenic pollutant input; bioavailability; PTE mapping; spatial data analysis

Air Pollutants: Sources, Characteristics, Environmental Impacts and Human Health Risks

edited by

Xiaotong Jiang

and Yinxiao Zhang

submission deadline 31 Jan 2027 | Viewed by 59 | Submission Open

Keywords: air pollution; source apportionment; air quality; PM2.5; atmospheric chemistry; biomass burning; data-driven analysis; toxicology; human health effects; environmental impacts; ozone

(This special issue belongs to the Section Air Pollution and Health)

The Carcinogenicity and Toxicology of Chemical Mixtures Using New Approach Methodologies

edited by Yansen Bai and Hao Wang

submission deadline 31 Jan 2027 | Viewed by 28 | Submission Open

Keywords: toxicology; epidemiology; omics; carcinogenicity; chemical mixtures; multi-exposure analysis method; epigenetics; hormesis

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Pregnancy and Lactation Period Exposure to Environmental Toxicants and the Effects on Maternal and Child Health

edited by

Lin Zhang

, C. Vyvyan Howard and

Ju Wang

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1467 | Submission Open

Keywords: pregnancy and lactation period exposure; environmental toxicants; maternal and child health; biomarkers; molecular mechanism; advanced methodologies; multi-omics techniques; network toxicology; computational modeling; risk assessment

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Heavy Metal-Induced Organ Damage: Mechanistic Insights and Advances in Toxicology

edited by Jingli Liu

submission deadline 28 Feb 2027 | Viewed by 28 | Submission Open

Keywords: heavy metal ; organ damage ; oxidative stress ; inflammation ; multi-omics ; new approach methodologies (NAMs) ; computational toxicology; systems toxicology; metal mixtures; risk assessment

(This special issue belongs to the Section Metals and Radioactive Substances)

Computational and Experimental Insights into Transformation of Environmental Pollutants

edited by Li Ji,

Dong-Xing Guan

and

Piotr Paneth

submission deadline 30 Apr 2027 | 1 articles | Viewed by 2002 | Submission Open

Keywords: pollutant transformation; reaction mechanism; kinetic isotope effects (KIE); computational toxicology; biotransformation; human health-risk assessment; transformation products; machine learning; environmental fate; emerging contaminants

(This special issue belongs to the Section Novel Methods in Toxicology Research)

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