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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biological Risk Monitoring of Exposure to Chemical Pollutants and/or Physical Agents: 2nd Edition

edited by

Mirta Milić

and

Nursen Basaran

submission deadline 29 Nov 2025 | 2 articles | Viewed by 3630 | Submission Open

Keywords: biomarkers of effect; biomarkers of exposure; biomarkers of susceptibility; DNA damage and repair; meta-analysis; biomonitoring; exposure; toxicokinetics and modes of action; risk assessment; epidemiology

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Identification of Emerging Pollutants and Human Exposure

edited by

Xiaotu Liu

and

Ting Wu

submission deadline 30 Nov 2025 | 3 articles | Viewed by 6481 | Submission Open

Keywords: emerging contaminants; remediation strategies; non-targeted analysis; biomonitoring; exposome; risk assessment

Concentration of VOCs in the Atmosphere and Its Environmental Exposure

edited by

Xinlei Ge

and

Ming Wang

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4887 | Submission Open

Keywords: VOCs; health risk assessment; exposure assessment; source identification; environmental impact

(This special issue belongs to the Section Emerging Contaminants)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and Inmaculada Varó

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3681 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Biological Effects and Mechanisms of Environmental Endocrine Disruptors

edited by Liting Zhou

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1485 | Submission Open

Keywords: environmental endocrine disruptors; epidemiological research; health effects; mixed exposure; emerging experimental models; mechanism

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Migration and Transformation of Emerging Pollutants and Improvement of Water Quality

edited by Shibao Lu and

Liang Pei

submission deadline 30 Nov 2025 | Viewed by 284 | Submission Open

Keywords: pollutant fate and transport; emerging contaminants; water remediation technologies; environmental nanotechnology; hydrobiogeochemical cycles; smart water management

From Detection to Risk: Data-Driven Advances in Analytical Chemistry and Toxicology

edited by

Nikiforos Alygizakis

submission deadline 30 Nov 2025 | Viewed by 216 | Submission Open

Keywords: analytical chemistry; computational mass spectrometry; toxicology; exposure assessment; chemical prioritization; mixture toxicity; environmental risk assessment

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Biomonitoring for Emerging Contaminants: From Detection to Risk Assessment

edited by Wenlong Li

submission deadline 10 Dec 2025 | 2 articles | Viewed by 1841 | Submission Open

Keywords: biomonitoring; emerging contaminants; risk assessment; detection; identification

Selected Papers from the 2nd International Online Conference on Toxics (IOCTO2025)

edited by

Xiaojun Luo

Mingce Long

, Patricia Ruiz and Maria João Bebianno

submission deadline 10 Dec 2025 | Viewed by 692 | Submission Open

Keywords: toxicology methods; toxicological mechanisms; organ toxicity; predictive toxicology

Evaluation and Biomonitoring of Potentially Toxic and Rare Earth Elements

edited by Ángel Rodríguez Hernández,

Manuel L Zumbado

and Carmen José Mateos Vega

submission deadline 19 Dec 2025 | 1 articles | Viewed by 909 | Submission Open

Keywords: potentially toxic elements (PTEs); rare earth elements (REEs); human biomonitoring; animal biomonitoring; environmental pollution; toxicological effects; risk assessment; oxidative stress; public health

Editorial Board Members’ Collection Series: Endocrine Disrupting Chemicals

edited by

Eduardo Rocha

and

Jing Liu

submission deadline 20 Dec 2025 | 3 articles | Viewed by 9729 | Submission Open

Keywords: EDCs; endocrine disruption; endocrine disorders; one health; xenohormones; environmental toxicology; mixture toxicity; plastics; pollution; reproductive toxicology

(This special issue belongs to the Section Emerging Contaminants)

Understanding the Trafficking of Toxic Metal(loid)s within Cells

edited by

Maikel Rosabal

and

Jürgen Gailer

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1540 | Submission Open

Keywords: subcellular toxicity; metal interactions; subcellular targets; molecular toxicity; organelles; detoxification; adverse effects; aquatic and terrestrial animals; human models

(This special issue belongs to the Section Metals and Radioactive Substances)

Environmental Toxicology and Risk Assessment of Priority Substances

edited by

Xin Zheng

, Tianxu Zhang and Shuhui Men

submission deadline 28 Dec 2025 | 7 articles | Viewed by 15109 | Submission Open

Keywords: Environmental toxicology; Risk assessment; Priority substances; New Approach Methodologies (NAMs); Emerging contaminant monitoring; Toxicity effects; Microcosm experiments

(This special issue belongs to the Section Emerging Contaminants)

Heavy Metals and Pesticide Residue Remediation in Farmland

edited by Ying Huang

submission deadline 30 Dec 2025 | 1 articles | Viewed by 807 | Submission Open

Keywords: heavy metal; pesticide residues; photocatalytic degradation; pollution evaluation; rice; combined pollution; phytoremediation; source; transfer; and accumulation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxic Mode of Action, Toxicity Testing, and Health Risks of Environmental Pollutants

edited by Weiwei Zheng and

Yuanyuan Ruan

submission deadline 31 Dec 2025 | 9 articles | Viewed by 28632 | Submission Open

Keywords: mode of action; toxicity testing; health risks; risk assessment; environmental pollutants

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Unraveling the Health Impacts of Air Pollution: Assessments and Mechanisms

edited by

Ting Wang

, Tingting Ku and

Jia Xu

submission deadline 31 Dec 2025 | 8 articles | Viewed by 14112 | Submission Open

Keywords: air pollution; exposure assessment; epidemiological study; toxic mechanisms; key components; health effects

(This special issue belongs to the Section Air Pollution and Health)

The Environment and Reproduction: Toxicity Assessment of Pollutant Exposure

edited by

Luigi Montano

submission deadline 31 Dec 2025 | 1 articles | Viewed by 10925 | Submission Open

Keywords: environmental toxicology; reproductive toxicity; pollutant exposure; endocrine disruptors; chemical pollutants; ecotoxicology; teratogenicity; bioaccumulation

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Impact of Per- and Polyfluoroalkyl Substances (PFAS) on Aquatic Animals: Immunotoxicity, Endocrine Disruption, and Beyond

edited by

Maurizio Manera

and

Luisa Giari

submission deadline 31 Dec 2025 | 3 articles | Viewed by 9800 | Submission Open

Keywords: new and old PFAS; animal model; one health; biomarker; immune system; endocrine system; toxic effects; in vivo and in vitro exposures

(This special issue belongs to the Section Ecotoxicology)

Ototoxic Chemical Exposures and Public Health

edited by

Thais C. Morata

, Gregory Zarus and Krystin Carlson

submission deadline 31 Dec 2025 | 2 articles | Viewed by 9752 | Submission Open

Keywords: early detection; diagnosis; treatment; prevention; occupational exposures; hearing; vestibular/balance; tinnitus/ringing

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Biomass Conversion and Organic Waste Utilization in Wastewater

edited by

Tingting Zhu

, Zisheng Zhao and Lihui Yang

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7180 | Submission Open

Keywords: organic wastewater; resource recovery; biomass conversion; added value products; energy recovery

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Carbon-Based Materials for Pollutant Immobilization and Removal in Soil and Water

edited by

Jianxin Fan

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5382 | Submission Open

Keywords: carbon-based materials; emerging pollutants; heavy metals; immobilization; removal

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

The Neuroexposome: Integrating Exposures with Physiology to Understand Brain Health and Disease

edited by Megan Mahoney and

Jennifer L. Freeman

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4787 | Submission Open

Keywords: exposome; exposomics; neuroexposome; neurodegeneration; neurotoxicology; neurodevelopment; developmental origins of health and disease (DOHAD)

(This special issue belongs to the Section Neurotoxicity)

Impact of Pollutants on Aquatic Ecosystems and Food Safety

edited by Francesca Falco

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4540 | Submission Open

Keywords: multi-stress; enviromental biodiversity; cascading effect; emerging contaminants; ecotoxicology; biomarkers

(This special issue belongs to the Section Emerging Contaminants)

Advances in Computational Methods of Studying Exposure to Chemicals

edited by Patricia Ruiz and Wei-Chun Chou

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4045 | Submission Open

Keywords: computational toxicology; machine learning; quantitative structure-activity relationship (QSAR); in silico modeling; molecular docking and molecular dynamics simulations; PBPK and PK modeling; fate and transport modeling; high-throughput screening (HTS); integrated testing strategies (ITS); artificial intelligence; risk assessment; adverse outcome pathway (AOP); new approach methodologies (NAMs); chemical mixtures

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Environmental Contaminant Exposure and Intake from Agricultural Products

edited by Sara Lambiase and

Mauro Esposito

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3658 | Submission Open

Keywords: persistent organic pollutants; metals and metalloids; emerging contaminants; targeted and untargeted analyses; food safety; feed safety; risk assessment

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Perspectives in Veterinary Toxicology and One Health

edited by

Wilson Kiiza Rumbeiha

and Abdel-Razak Kadry

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2906 | Submission Open

Keywords: climate change and animal health; animals as biosentinels of environmental pollution; pollutants and animal health; one health toxicology; veterinary toxicology; environmental toxicants modulating animal health

Biomarkers of Oxidative Stress from Environmental and Occupational Exposure: Implications for Health Risk Assessment

edited by

Ata Rafiee

, Peter Sly and Mohammad Hoseini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2571 | Submission Open

Keywords: biomarkers; human biomonitoring; health risk assessment; oxidative stress

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Ecotoxicological Effects of Microplastics on the Soil Environment

edited by

Rogers Wainkwa Chia

, Charles Amanze and Modupe Elizabeth Ojewumi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2260 | Submission Open

Keywords: microplastics; soil ecosystems; soil fertility; food security; ecotoxicological risks; soil contamination; sustainable waste management

(This special issue belongs to the Section Ecotoxicology)

Applicability of New Approach Methodologies (NAMs) to Skin Sensitization: Insights from Industry and Regulatory Perspectives

edited by Gertrude-Emilia Costin and Argel Islas-Robles

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2142 | Submission Open

Keywords: skin sensitization; allergic contact dermatitis; new approach methodologies; regulatory testing; defined approaches; adverse outcome pathway; cosmetic industry; medical devices; mixtures; botanicals

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Environmental Contamination, Toxic Effect, and Risk Assessment of Microplastics and Plastic Additives

edited by

Yu Wang

Chu Peng

and

Lili Rong

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1738 | Submission Open

Keywords: microplastics; plastic additives; environmental contamination; biomonitoring; bioaccumulation; toxicity mechanism; ecological risk assessment; human health effect

(This special issue belongs to the Section Emerging Contaminants)

Pharmacological Intervention Against Toxicity of Environmental Pollutants and Stresses

edited by

Dayong Wang

Natalia Krasteva

and Tianshu Wu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1665 | Submission Open

Keywords: toxicology; ecotoxicology; pharmacology; environmental pollutant; environmental stress; health protection

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Occurrence, Fate, Bioaccumulation and Toxic Effects of 6PPDQ

edited by

Yuxin Sun

Xiaojun Luo

and

Dayong Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 777 | Submission Open

Keywords: 6PPDQ; environmental behavior; bioaccumulation; toxicity; human exposure; transformation product; risk assessment

(This special issue belongs to the Section Emerging Contaminants)

Environmental Behavior and Migration Mechanism of Microplastics

edited by

Jiji Li

and

Fabiana Corami

submission deadline 31 Dec 2025 | Viewed by 544 | Submission Open

Keywords: environmental toxicology; emerging methodologies; risk assessment; omics technologies; chemical mixtures; nanomaterials; in silico models

Detection and Degradation of Organic Pollutants

edited by

Dongyang He

Jiao Qu

and Xiaolin Zhu

submission deadline 31 Dec 2025 | Viewed by 385 | Submission Open

Keywords: pollutant detection; quantitative detection; sensor; toxicity; pollutant degradation; photocatalysis; electrocatalysis

Emerging Pollutants and Livestock Health

edited by

Shuhua Yang

Shu-cheng Huang

and Yuhang Sun

submission deadline 31 Dec 2025 | Viewed by 349 | Submission Open

Keywords: mycotoxin; endocrine disrupting chemicals; heavy-metal pollution; microplastics; toxin; detoxicant; persistent organic pollutants

Impact of Toxic and Harmful Volatile Organic Compounds on Health and Ecology

edited by

Hong Li

Junling Li

and Yuanyuan Ji

submission deadline 31 Dec 2025 | Viewed by 253 | Submission Open

Keywords: anthropogenic and natural emissions of atmospheric VOCs; transformation; transport and deposition of atmospheric VOCs; impact of VOCs on the atmospheric environment; human health risk assessment of toxic atmospheric VOCs; characterization; sources and control of ODS; monitoring; alternative abatement technologies and environmental impact of fluorinated greenhouse gases; sources analysis techniques for atmospheric VOCs

Biochar-Enhanced Remediation of Heavy Metal-Induced Soil and Water Environmental Degradation: Microbial and Functional Material Perspectives

edited by

Longfei Liu

Shengsen Wang

and

Wan Yang

submission deadline 31 Dec 2025 | Viewed by 181 | Submission Open

Keywords: carbon-based remediation materials; multi-media synergistic remediation; multidimensional ecological risk assessment; microplastic-heavy metal interactive contamination; microinterface modulation technology; co-occurrence of persistent organic pollutants; migration; transformation; and fate of heavy metals

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Cadmium Exposure and Health Impact

edited by

Teresa Urbano

and

Tommaso Filippini

submission deadline 31 Dec 2025 | Viewed by 176 | Submission Open

Keywords: sources and pathways of cadmium exposure; with a particular focus on diet; mechanisms of cadmium toxicity; genomic and epigenomic effects of cadmium; cadmium exposure and bone metabolism; cancer; cardiovascular; kidney; and neurodegenerative diseases; vulnerable populations and susceptibility to cadmium exposure; biomarkers of cadmium exposure; public health implications of cadmium exposure

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Monitoring and Modeling of Air Pollution

edited by

Cheng Liu

Yongjing Ma

and

Yangzhou Wu

submission deadline 9 Jan 2026 | 1 articles | Viewed by 598 | Submission Open

Keywords: air pollution; anthropogenic emissions; meteorological conditions; source apportionment; health risk; numerical simulations

(This special issue belongs to the Section Air Pollution and Health)

Natural Compounds’ Mitigation of Toxicity: Insights into Health Protection

edited by Arielle Cristina Arena and Cândida Aparecida Leite Kassuya

submission deadline 10 Jan 2026 | Viewed by 117 | Submission Open

Keywords: natural compounds; toxicity mitigation; phytochemicals; oxidative stress; xenobiotic metabolism; chemoprevention; environmental toxicants; protective mechanisms; integrative therapies

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Molecular Insights into Drugs in Livestock: Oxidative Stress, Metabolism and Toxicity

edited by

Liping Wang

submission deadline 14 Jan 2026 | Viewed by 77 | Submission Open

Keywords: drug– drug interaction in livestock; drug toxicity; oxidative stress; veterinary drugs and gut microbiome; oxidative damage biomarkers; ROS generation by veterinary drugs; mitigation strategies and alternatives

(This special issue belongs to the Section Drugs Toxicity)

Advances in Remediation of Environmental Pollutants in Soil-Water System

edited by Fenghe Wang, Haotian Hao and Jiahe Miao

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3317 | Submission Open

Keywords: environmental remediation; persistent organic pollutants (POPs); microplastics; emerging contaminants; heavy metals; phytoremediation; nanoremediation; electrochemical remediation; bioremediation; integrated remediation technologies.

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxicity and Molecular Mechanisms of Environmental Contaminants on Animals

edited by

Chunmei Li

and Dan Shen

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2746 | Submission Open

Keywords: environmental toxicants; animal health; molecular pathways; bioaccumulation; toxic injury

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Toxicity of Phthalate Esters (PAEs)

edited by

Zhenxing Chi

submission deadline 16 Jan 2026 | 2 articles | Viewed by 2268 | Submission Open

Keywords: phthalate esters; toxic mechanism; toxic effect; in vivo study; in vitro study

(This special issue belongs to the Section Emerging Contaminants)

Ecotoxicology of Pollutants of High Concern

edited by

Rui Zhang

, Yuwei Xie and Pu Xia

submission deadline 16 Jan 2026 | 1 articles | Viewed by 1085 | Submission Open

Keywords: persistent organic pollutants; emerging contaminants; environmental behavior; mechanistic toxicology; ecotoxicology; environmental monitoring and biomonitoring; environmental risk assessment; human risk assessment

Eyes Toward the Future: Environmental Endocrine Disruptors (EDCs) and Animal Health

edited by

Jill Jenkins

submission deadline 16 Jan 2026 | Viewed by 209 | Submission Open

Keywords: reproduction; fertility; personal care products; organic wastewater contaminants; adverse outcome pathway; biomarkers; per- and polyfluorinated alkyl substances (PFASs)

New Risk Assessment of Per- and Polyfluoroalkyl Substances (PFAS) Exposure to Livestock

edited by Lorraine MacKenzie and Antti Mikkonen

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3697 | Submission Open

Keywords: per- and polyfluoroalkyl substances (PFASs); PFAS risk assessment; PFAS livestock exposure models; PFAS toxicokinetics; PFAS environmental guidelines

(This special issue belongs to the Section Emerging Contaminants)

Toxic Agent Analysis and Removal for Healthy Living and Safe Environment

edited by

Petru Negrea

and

Nicoleta Sorina Nemeş

submission deadline 20 Jan 2026 | 4 articles | Viewed by 3471 | Submission Open

Keywords: toxic agents; human health; environmental protection; heavy metals; polycyclic aromatic hydrocarbons; pesticides; xenobiotics

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Ecological Restoration and Treatment of Metal Contamination from Mines

edited by

Liang Hu

and Luhua Jiang

submission deadline 23 Jan 2026 | 1 articles | Viewed by 2121 | Submission Open

Keywords: heavy metal; rare earth; migration and transformation; occurrence state; stabilization; carbon sequestration; environmental risk; ecological restoration; microbial technology

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Neurological and Endocrine Impacts of Pollutants on Aquatic Organisms

edited by Wenjun Shi

submission deadline 23 Jan 2026 | 2 articles | Viewed by 1457 | Submission Open

Keywords: aquatic organisms; neurotoxicity; endocrine disruption effects; ecotoxicology; emerging pollutants; toxicity and risk assessment; toxicity prediction

(This special issue belongs to the Section Ecotoxicology)

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