Environmental Toxicants in Human Health: Oxidative Stress, Metabolism and Toxicity

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Human Toxicology and Epidemiology".

Deadline for manuscript submissions: 15 June 2026 | Viewed by 17

Special Issue Editors


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Guest Editor
Department of Biomedical Sciences, College of Integrated Health Sciences, University at Albany, Albany, NY 12222, USA
Interests: the microbiome-gut–brain axis; neuroimmunology; immunotoxicology

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Guest Editor
Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA
Interests: immunobiology of stress; inflammation; metallothionein; autoimmune and chronic inflammatory disease; surface plasmon microarrays; antibody therapeutics

Special Issue Information

Dear Colleagues,

The focus of the Special Issue is on direct toxicant effects on immune cells leading to pathology due to loss of immunohomeostasis from disbalance of immune effector and regulatory immune cells, in addition to the indirect effects of toxicants causing dysbiosis and/or cell damage on non-immune cells causing loss of immunohomeostasis. Loss of immune homeostasis may lead to excessive inflammation and oxidative stress as well as autoantibodies and autoreactive cytolytic T cells, but less responsiveness to cancers and senescent cells.

The Special Issue will also cover developmental and aging aspects of toxicants on immunity including involvement of ion fluxes, protein translation and aggravation, and intracellular and extracellular modulations. Multi-omic technologies useful for systemic modulations will be included such as single-cell proteomics and transcriptomics.

Dr. David A. Lawrence
Dr. Michael Lynes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • environmental toxicants
  • immune cells
  • inflammation
  • oxidative stress
  • developmental and aging
  • autoimmunity

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Published Papers

This special issue is now open for submission.
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