Emerging Contaminants in a Changing World: Implications for Human Health

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Emerging Contaminants".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 1562

Editors


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Department of Medical, Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia, 87-95123 Catania, Italy
Interests: environmental health; food hygiene; health education; public health; emerging contaminant

E-Mail Website
Guest Editor
Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia, 87-95123 Catania, Italy
Interests: environmental health; food hygiene; health education; public health; emerging contaminant
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Special Issue Information

Dear Colleagues,

In recent years, rapid industrial development, technological innovation, climate change, and other global environmental transformations have contributed to the increasing presence of emerging contaminants in ecosystems and human environments. In a changing world, substances such as per- and polyfluoroalkyl substances (PFAS), microplastics, pharmaceuticals, and other novel chemical compounds are increasingly detected in air, water, soil, food, and biological matrices, raising growing concerns about their potential implications for human health.

Human exposure to these contaminants may occur through multiple pathways, including dietary intake, drinking water consumption, occupational exposure, and environmental contact. Although many emerging contaminants are often present at low concentrations, their persistence, bioaccumulation potential, and possible combined effects highlight the need for further research to better understand their toxicological profiles and long-term health implications.

This Special Issue aims to collect original research articles, reviews, and interdisciplinary studies addressing the occurrence, environmental distribution, human exposure pathways, toxicological mechanisms, and health effects associated with emerging contaminants. By bringing together contributions from environmental science, toxicology, epidemiology, and public health, this Special Issue seeks to improve the understanding of emerging contaminants and support evidence-based strategies for environmental monitoring, risk assessment, and preventive public health policies.

Dr. Andrea Moscato
Dr. Maria Fiore
Guest Editors

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Keywords

  • emerging contaminants, PFAS, TFA, micro- and nano-plastics
  • environmental exposure
  • risk assessment
  • environmental epidemiology
  • toxicological effects

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Published Papers (1 paper)

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Review

16 pages, 1120 KB  
Review
Occurrence of Trifluoroacetic Acid in Wine and Its Relevance for Dietary Exposure and Human Health: A Narrative Review
by Andrea Moscato, Paola Rapisarda, Margherita Ferrante and Maria Fiore
Toxics 2026, 14(6), 454; https://doi.org/10.3390/toxics14060454 - 22 May 2026
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Abstract
Trifluoroacetic acid (TFA) is an ultrashort-chain perfluoroalkyl substance (PFAS) characterized by environmental persistence, water solubility, and a growing global presence, resulting primarily from the degradation of fluorinated compounds. Evidence suggests that plant-based foods may represent an underestimated exposure route, with wine emerging as [...] Read more.
Trifluoroacetic acid (TFA) is an ultrashort-chain perfluoroalkyl substance (PFAS) characterized by environmental persistence, water solubility, and a growing global presence, resulting primarily from the degradation of fluorinated compounds. Evidence suggests that plant-based foods may represent an underestimated exposure route, with wine emerging as a significant dietary source due to accumulation in soils, irrigation water, and plant uptake. This review provides an updated summary of the evidence on the environmental sources and temporal evolution of TFA in wine, its analytical detection, its contribution to dietary exposure, potential implications for human health, and current regulatory attention. A structured but non-systematic literature search was conducted using PubMed and Scopus, supplemented by European reports and monitoring data, and in accordance with SANRA guidelines. Evidence shows that TFA concentrations in wine derive from widespread environmental sources and have increased over time, from negligible levels before the 1970s to a marked increase in recent decades. Reported concentrations range from tens to several hundred µg/L, despite analytical challenges. Exposure estimates indicate that wine may contribute significantly to total dietary TFA intake in regular consumers. Although toxicological data suggest low acute toxicity, uncertainties remain regarding long-term exposure, and regulatory limits for TFA in foods and beverages are lacking. Full article
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