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  • Review
  • Open Access
31 Views
27 Pages

Cancer-Associated Fibroblasts: Clinical Applications in Imaging and Therapy

  • Neda Nilforoushan,
  • Ashkan Khavaran,
  • Maierdan Palihati,
  • Yashvi Patel,
  • Anna O. Giarratana,
  • Jeeban Paul Das and
  • Kathleen M. Capaccione

17 December 2025

Cancer-associated fibroblasts (CAFs) are an abundant and diverse cell population within tumor microenvironments of solid tumors. Multiple subtypes of CAFs, defined by molecular and functional markers, have been described in the literature. CAFs contr...

  • Article
  • Open Access
58 Views
16 Pages

Prediction of Breast Radiation Absorbed Dose Chest CT Examinations Using Machine Learning Techniques

  • Sevgi Ünal,
  • Remzi Gürfidan,
  • Merve Gürsoy Bulut and
  • Mustafa Fazıl Gelal

16 December 2025

Background/Objectives: The breast is a highly radiosensitive organ that is directly exposed to ionizing radiation during chest computed tomography (CT) examinations. Excessive radiation exposure increases the risk of radiation-induced malignancies, h...

  • Article
  • Open Access
56 Views
11 Pages

16 December 2025

Background: Accurate volumetry and imaging characterization of chronic subdural hematoma (cSDH) are essential for prognostication and treatment planning, but manual assessment is time-consuming and therefore underutilized. Methods: We retrospectively...

  • Article
  • Open Access
82 Views
12 Pages

Pilot Evaluation of a Deep Learning Model for Nasogastric Tube Verification on Chest Radiographs: A Single-Center Retrospective Study

  • Sang Won Park,
  • Doohee Lee,
  • Jae Eun Song,
  • Yoon Kim,
  • Hyun-Soo Choi,
  • Seung-Joon Lee,
  • Woo Jin Kim,
  • Kyoung Min Moon and
  • Oh Beom Kwon

15 December 2025

Background: Accurate confirmation of nasogastric (NG) tubes is essential for patient safety, but delays and variability in interpretation remain common in clinical practice. Deep learning (DL) models have shown potential for assisting in this task, b...

  • Article
  • Open Access
148 Views
12 Pages

Aortic Valve Calcium Scoring Using True and Virtual Non-Contrast Reconstructions on Photon-Counting CT with Differing Slice Increments: Impact on Calcium Severity Classifications

  • Mandeep Singh,
  • Amirhossein Moaddab,
  • Doosup Shin,
  • Jonathan Weber,
  • Karen Chau,
  • Ali H. Dakroub,
  • Roosha Parikh,
  • Karli Pipitone,
  • Ziad A. Ali and
  • Omar K. Khalique

11 December 2025

Background/Objectives: Aortic valve calcification is commonly evaluated using 3.0 mm true non-contrast (TNC) computed tomography (CT) images. This study evaluates the reproducibility of virtual non-contrast (VNC) reconstructions at different slice in...

  • Article
  • Open Access
138 Views
15 Pages

10 December 2025

Background/Objectives: Breast cancer is one of the most common malignancies in women worldwide. Early diagnosis and accurate classification in breast cancer detection are among the most critical factors determining treatment success and patient survi...

  • Article
  • Open Access
139 Views
16 Pages

5 December 2025

Background/Objectives: To identify preoperative MRI features using computer-assisted diagnosis (CAD) that are associated with invasive disease-free survival (IDFS) and distant metastasis-free survival (DDFS) in patients with primarily operable triple...

  • Article
  • Open Access
160 Views
14 Pages

Quantitative Magnetic Resonance Imaging of the Forearm in Myotonic Dystrophy Type 1

  • Sydney Eierle,
  • Tanja Taivassalo,
  • Hyunjun Park,
  • Korey D. Cooke,
  • Zahra Moslemi,
  • Sean C. Forbes,
  • Glenn A. Walter,
  • Krista Vandenborne,
  • S. H. Subramony and
  • Donovan J. Lott

5 December 2025

Introduction: Myotonic dystrophy type 1 is the most prevalent muscular dystrophy in adults, characterized by weakness, impaired functional abilities, and myotonia. However, little is known about the relationship between quantitative MRI measures (fat...

  • Article
  • Open Access
225 Views
15 Pages

Evaluation of Projection Images for Visual Quality Control of Automated Left and Right Lung Segmentations on T1-Weighted MRI in Large-Scale Clinical Cohort Studies

  • Tobias Norajitra,
  • Christopher L. Schlett,
  • Ricarda von Krüchten,
  • Prerana Agarwal,
  • Ashis Ravindran,
  • Thuy Duong Do,
  • Lisa Kausch,
  • Stefan Karrasch,
  • Hans-Ulrich Kauczor and
  • Klaus Maier-Hein
  • + 1 author

29 November 2025

Background/Objectives: To assess diagnostic accuracy of two-dimensional (2D) projection methods for rapid visual quality control of automated volumetric (3D) lung segmentations compared with slice-based 3D review of segmentation results for applicati...

  • Article
  • Open Access
300 Views
11 Pages

A Question of Dose? Ultra-Low Dose Chest CT on Photon-Counting CT in People with Cystic Fibrosis

  • Marcel Opitz,
  • Matthias Welsner,
  • Halil I. Tazeoglu,
  • Florian Stehling,
  • Sivagurunathan Sutharsan,
  • Dirk Westhölter,
  • Erik Büscher,
  • Christian Taube,
  • Nika Guberina and
  • Denise Bos
  • + 7 authors

27 November 2025

Objective: Chest computed tomography (CT) is a key component of the diagnostic assessment of people with cystic fibrosis (PwCF) and is increasingly replacing chest radiography. Due to improvements in life expectancy, radiation exposure has become a g...

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Tomography - ISSN 2379-139X