Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 100
Special Issue Editor
Interests: antioxidant activity; antimicrobial activity; metal complexes; molecular docking; DFT calculations; enzyme inhibition; drug design
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metal-based compounds represent a dynamic and expanding field of research in the development of novel antimicrobial agents. Their unique coordination environments, redox activity, and ability to interact selectively with biomolecular targets offer significant advantages over traditional small-molecule drugs. Given the global rise in antimicrobial resistance, exploring metal complexes as therapeutic agents is more important than ever.
We are pleased to invite you to contribute to the Special Issue, titled “Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications”, which aims to highlight recent progress in the synthesis, characterization, biological evaluation, and pharmacokinetic profiling of metal complexes with antimicrobial activity. In particular, we encourage submissions that combine computational or modeling approaches with experimental validation, especially those including pharmacodynamic and pharmacokinetic studies, to ensure biological relevance and translational impact. This topic aligns well with the scope of the journal, emphasizing drug development and bioinorganic chemistry.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) structure–activity relationships, mechanisms of antimicrobial action, metal–ligand design strategies, computational modeling supported by biological experiments, pharmacokinetics, and preclinical evaluation.
We look forward to receiving your valuable contributions.
Dr. Žiko B. Milanović
Guest Editor
Manuscript Submission Information
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Keywords
- metal complexes
- antimicrobial agents
- drug development
- therapeutic agents
- pharmacokinetics
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