Metal Nanoparticles for Controlled Release of Drugs and Bioactive Compounds
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 89
Special Issue Editors
Interests: metallic nanoparticles; metal oxides; biopolymers and hybrid materials; drug delivery systems; electrospun nanofibers; nanoparticle–cell interactions; nanoemulsions and microparticles; sustainable nanocomposites; in silico drug release modeling; magnetic nanoparticles for biomedicine; encapsulation of bioactives
Special Issues, Collections and Topics in MDPI journals
Interests: nanoparticle synthesis; green synthesis routes; metal and metal oxide nanostructures; plasmonic nanoparticles; hierarchical superstructures; microemulsions and colloidal systems; surface functionalization; SERS substrates and plasmonic sensing; controlled and sustained drug release; bioactive compound delivery; nanocarriers for cancer therapy; gene delivery nanosystems; electrochemical biosensors; preclinical nanomedicine applications; theranostics
Special Issues, Collections and Topics in MDPI journals
Interests: pharmaceutical formulation; delivery and controlled-release systems for drugs, vaccines, and biopharmaceuticals; pharmaceutical process, engineering, biotechnology, and nanotechnology; devices, cells, molecular biology, and materials science related to drugs and drug delivery; nanomedicine; drug targeting; effects of the body on drugs (absorption, distribution, metabolism, excretion); physiological and biochemical effects of drugs on the body; systematic reviews
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metal nanoparticles are a global focus in nanomedicine, offering the precise control of size and shape, high surface area, biomolecule functionalization, and plasmonic properties that enable tunable biodistribution, controlled release, and theragnostic functions. Green synthesis broadens their appeal, while advanced techniques like SERS enable real-time monitoring of active compound release. The Special Issue is motivated by the rapid global expansion of research on metal nanoparticles as versatile platforms for the controlled delivery of drugs and bioactive compounds. Its main aim is to consolidate mechanistic knowledge connecting nanoparticle intrinsic properties—size, shape, composition, and surface chemistry—to drug loading, release kinetics, and biological fate.
The following areas will be covered by the Special Issue:
- Synthesis and physico-chemical characterization of metal nanoparticles, including green routes with plant extracts and biosynthesis.
- Quantitative release kinetics and modelling (Weibull, Korsmeyer-Peppas, mechanistic transport models).
- In vitro simulation of physiological environments (gastric pH, intestinal pH, pH 7.4, enzymatic conditions).
- Advanced analytical approaches (SERS, plasmonic sensing, real-time label-free monitoring).
- Correlation of nanoparticle design with biodistribution, safety and PK/PD in preclinical models.
- Studies on delivery of conventional drugs, natural extracts, biomolecules, gene delivery.
- Surface engineering and targeting strategies that modulate release.
We invite original research articles and comprehensive reviews that provide quantitative release data, validated kinetic modelling, mechanistic insights, or novel analytical tools. Systematic reviews addressing clear questions in areas covered in this Special Issue are welcome. Submissions should prioritize clear linkage between nanoparticle properties and release behaviour, include appropriate controls and reproducible methods, and discuss translational considerations such as safety, standardization, and regulatory aspects.
Dr. Perla Elvia García-Casillas
Dr. Margarita Sanchez-Dominguez
Dr. Christian Chapa
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gold nanoparticles
- metal nanoparticles
- drug delivery systems
- controlled release
- pharmacokinetics
- Surface-Enhanced Raman Scattering (SERS)
- green synthesis
- preclinical studies
- release kinetics
- theragnostics
- gene delivery
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
