Recent Advances in Gastrointestinal Disease: Insights into Drug Delivery and Cellular and Molecular Mechanisms for Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 120
Special Issue Editors
Interests: GI cell physiology and pathophysiology; homeostasis mechanisms; transepithelial and transmembrane transport processes; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) diseases include a wide range of conditions affecting the digestive tract, including cancer, chronic inflammatory and immune diseases, and functional and metabolic disorders. Recent advancements in cellular and molecular biology have provided critical insights into the underlying pathophysiology of these disorders, facilitating the development of more precise and effective therapeutic strategies that minimize damage to healthy cells and significantly reduce side effects. The substantial progress in genomic technologies and multi-omics approaches has allowed the identification of new potential targets involved in dysfunctional signaling pathways and the tailoring of innovative and specific therapy like novel small-molecule inhibitors, RNA-based molecules, monoclonal antibodies, immunotherapy and immune checkpoint inhibitors. In addition, innovative drug delivery platforms and modeling techniques are enhancing our knowledge of drug efficacy and cellular heterogeneity, providing deeper insights into the pharmacodynamic, pharmacokinetic, immunogenic and toxicological properties of drugs.
This Special Issue invites researchers to submit original research articles or reviews exploring drug delivery systems. Promising strategies for drug delivery to improve compound bioavailability and stability, cell physiological responses and on-target drug distribution are of broad interest.
Submissions focused on, but not limited to, novel therapeutic strategies to enhance treatment efficacy in GI diseases, and combination and multi-targeted therapies are all welcome.
Dr. Amilcare Barca
Dr. Emanuele Piccinno
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gastrointestinal disease
- drug delivery
- molecular therapy
- biological therapy
- target therapy
- molecular target
- biomarkers
- GI epithelial cells
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