Electrospinning for Biomedical Applications

Dear Colleagues,

Electrospinning offers an exceptional level of control over fiber morphology, composition, and surface functionality, making it a powerful tool for engineering materials that mimic the structural intricacy of biological tissues. Its historical progression from a laboratory curiosity to a cornerstone of biomedical material science reflects both its adaptability and its capacity to address unmet needs in pharmaceutical technology. Today, electrospun constructs are increasingly considered for applications requiring precision, biocompatibility, and the ability to modulate molecular transport.

This Special Issue investigates the rapidly expanding landscape of electrospinning for biomedical applications, with a focus on how fiber-based architectures can be tailored to influence biological responses at multiple scales. Contributions in this volume explore strategies for optimizing polymer selection, incorporating bioactive cues, engineering multi-layer or composite systems, and integrating electrospinning with emerging fabrication approaches. Together, these studies demonstrate how this technology can contribute to controlled drug delivery, guided tissue regeneration, advanced wound care, biosensing, and implantable therapeutic platforms.

At the forefront of current research are dynamic and stimuli-responsive systems, fiber networks designed to regulate cell fate, and electrospun materials that bridge the gap between in vitro modelling and clinical translation. These developments illustrate the move toward more predictive and functional biomedical devices.

The Special Issue seeks submissions that provide rigorous experimental evidence, thoughtful mechanistic interpretation, and clear advancement beyond existing methodologies. Work that connects material design with therapeutic performance, safety, and manufacturability is particularly encouraged.

Dr. Elisa Capuana
Dr. Vincenzo La Carrubba
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.