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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Influenza A Virus: Updates and Insights

edited by

Pawel Zmora

and

Elzbieta Kierzek

submission deadline 10 Jan 2026 | 1 articles | Viewed by 2072 | Submission Open

Keywords: influenza A virus; virus– host interactions; antivirals; vaccines; epidemiology; genetic diversity; RNA structure; RNA interactions; structural biology

(This special issue belongs to the Section Viral Pathogens)

The Dark Side of Fungi: Exploring Pathogenesis in Candida and Other Fungal Pathogens

edited by

Bruna Gonçalves

Stephen A. Klotz

and

Ana V. Espinel-Ingroff

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2169 | Submission Open

Keywords: fungal pathogenesis; Candida species; virulence factors; fungi– host interaction; immune evasion; antifungal resistance

(This special issue belongs to the Section Fungal Pathogens)

Molecular and Cellular Research on Targets for Antimalarial Therapy Development

edited by

Sanjay Arvind Desai

submission deadline 15 Jan 2026 | 1 articles | Viewed by 1637 | Submission Open

Keywords: malaria; molecular biology; cellular biology; antimalarial drug discovery and development; malaria vaccines

(This special issue belongs to the Section Parasitic Pathogens)

Pathogens in Dentistry: Diversity, Virulence, Resistance, and Control

edited by

Gláuber Campos Vale

submission deadline 15 Jan 2026 | Viewed by 143 | Submission Open

Keywords: oral pathogens; biofilm; dental caries; periodontitis; virulence factors; antimicrobial resistance; microbiome; infection control; molecular diagnostics; host immunity

Biomarkers and Diagnostic Advances in Oral Pathogen Detection: Exploring Microbial Diversity and Clinical Applications

edited by

Aleksandar Jakovljevic

submission deadline 15 Jan 2026 | Viewed by 118 | Submission Open

Keywords: oral pathogens; biomarkers; diagnostic methods; microbial diversity; personalized medicine

New Insights into Rickettsia and Related Organisms

edited by

Alison Luce-Fedrow

and Kristin E. Mullins

submission deadline 20 Jan 2026 | 4 articles | Viewed by 7076 | Submission Open

Keywords: Rickettsia; Orientia; Ehrlichia; Anaplasma; Coxiella; Borrelia; Bartonella; Babesia

(This special issue belongs to the Section Bacterial Pathogens)

Hand–Foot–Mouth Disease

edited by

Kow-Tong Chen

submission deadline 20 Jan 2026 | 2 articles | Viewed by 5425 | Submission Open

Keywords: hand– foot– mouth disease; Coxsackie virus; epidemiology; pathogenesis; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Updates on Animal Papillomaviruses

edited by

Francesca De Falco

and Franco Roperto

submission deadline 20 Jan 2026 | 2 articles | Viewed by 4400 | Submission Open

Keywords: papillomavirus; trans-species transmission; environmental contamination

(This special issue belongs to the Section Viral Pathogens)

Current Research on Bacillus anthracis Infection

edited by Viviana Manzulli and

Domenico Galante

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3290 | Submission Open

Keywords: Bacillus anthracis; epidemiology; pathogenesis; diagnostics; genomics

(This special issue belongs to the Section Bacterial Pathogens)

Immune Pathways and Mechanisms Involved in Viral Infections

edited by

Celina Monteiro Abreu

, Lendel Correia Da Costa, Ana Carolina Soares and

Isadora Alonso Corrêa

submission deadline 20 Jan 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: viral infections; host– virus interactions; immune pathways; viral evasion; antiviral therapies; vaccine development

(This special issue belongs to the Section Viral Pathogens)

Genomic Applications in Microbial Adaptation, Antimicrobial Resistance and One Health Perspectives

edited by

Wellington Rodrigues

Aristóteles Góes-Neto

and Siomar de Castro Soares

submission deadline 20 Jan 2026 | Viewed by 209 | Submission Open

Keywords: genomics; One Health; antimicrobial resistance; pathogen evolution; metagenomics; reverse vaccinology; zoonotic diseases; mobilome; genomic surveillance; predictive modeling

Emerging and Neglected Zoonotic Pathogens in Companion Animals

edited by Olga Szalus̈-Jordanow

submission deadline 20 Jan 2026 | Viewed by 96 | Submission Open

Keywords: zoonotic pathogens; host– pathogen interactions; companion animals; one Health; antimicrobial resistance; emerging infectious diseases; interspecies transmission; molecular epidemiology; pathogen surveillance

(This special issue belongs to the Section Emerging Pathogens)

Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes: 2nd Edition

edited by

Antonella Marangoni

and

Claudio Foschi

submission deadline 25 Jan 2026 | 3 articles | Viewed by 6629 | Submission Open

Keywords: vaginal microbiome; vaginal metabolome; lactobacilli; host– pathogen interactions; sexually transmitted infections; Chlamydia; gonorrhea; vaginal dysbiosis; vulvovaginal candidiasis; animal models

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Leveraging Technological Advancement for Pandemic Preparedness

edited by Kai Sen Tan,

Chee Keng MOK

Yaw Shin Ooi

, Chee Wah Tan,

Mookkan Prabakaran

, Dahai Luo and Poying Chia

submission deadline 25 Jan 2026 | 1 articles | Viewed by 1967 | Submission Open

Keywords: pandemic preparedness; disease X; technological platforms; treatment and prevention; viral infectious diseases

New Insights Into Zoonotic Intracellular Pathogens

edited by

Tarka Raj Bhatta

, Stephen Graves and

John Stenos

submission deadline 25 Jan 2026 | 2 articles | Viewed by 1688 | Submission Open

Keywords: zoonotic intracellular pathogens; bacteria; viruses; sequencing; virulence factors; immune system; vaccine development; diagnostic tools; one health

Exploring Natural Products as Antiparasitic Agents: Efficacy Against Parasites of Veterinary and Public Health Significance

edited by

Agustín Olmedo-Juárez

and

Elke Von Son-De Fernex

submission deadline 31 Jan 2026 | 6 articles | Viewed by 7603 | Submission Open

Keywords: plant extracts; phytochemicals; fungi; parasites; anthelmintics; secondary metabolites; natural compounds; ethnoveterinary

(This special issue belongs to the Section Parasitic Pathogens)

Salmonella: A Global Health Threat and Food Safety Challenge

edited by

Chyer Kim

and

Yangjin Jung

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7301 | Submission Open

Keywords: salmonellosis; virulence; surveillance; climate change; and prevention

(This special issue belongs to the Section Bacterial Pathogens)

Pets, Wildlife and Parasites—2nd Edition

edited by

Anastasia Diakou

Georgiana Deak

and

Fabrizia Veronesi

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3343 | Submission Open

Keywords: pet animals; dog; cat; wildlife; wild animals; parasites; zoonosis

(This special issue belongs to the Section Parasitic Pathogens)

The Interplay of Microbiota and Polyomaviruses in Human Health and Disease

edited by

Valeria Pietropaolo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2994 | Submission Open

Keywords: human polyomaviruses (HPyVs); microbiota; co-infection patterns; cancer; diagnostic markers; cellular pathways; immunosuppression

(This special issue belongs to the Section Viral Pathogens)

Advances in the Surveillance and Prevention of Healthcare-Associated Infections

edited by

Francesca J. Torriani

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2262 | Submission Open

Keywords: healthcare-associated infections (HAIs); nosocomial infections; HAI-associated pathogens; infection prevention and control; antimicrobial resistance and antimicrobial stewardship

Infectious Diseases in Aquatic Animals

edited by Roberto Bermúdez Pose

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2219 | Submission Open

Keywords: infectious diseases; aquatic animals; pathogens; host– pathogen interactions; immune response

Hospital-Acquired Infections: Risk Factors and Preventions—2nd Edition

edited by

Gabriele Messina

and

Davide Amodeo

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1634 | Submission Open

Keywords: surgical site infection; dialysis infection; burn infection; bacterial infections; Legionella; Clostridium difficile; ventilator-associated pneumonia prevention; female urinary catheter in urinary tract infection prevention; endoscope sterilisation and disinfection

Advances in Molecular Characterization and Epidemiology of Plant Viruses

edited by

Nicolas Bejerman

submission deadline 31 Jan 2026 | 1 articles | Viewed by 807 | Submission Open

Keywords: plant viruses; metatranscriptomics; epidemiology; viral diseases; virus detection

(This special issue belongs to the Section Viral Pathogens)

Infectious Diseases in Pediatric Populations: Clinical Challenges and Emerging Perspectives

edited by Piero Pavone,

Roberta Leonardi

and Manuela Lo Bianco

submission deadline 31 Jan 2026 | 1 articles | Viewed by 635 | Submission Open

Keywords: pediatric infectious diseases and immune responses; post-infectious syndromes; diagnosis and treatment of pediatric infectious diseases; pediatric microbiome; viral; fungal; and bacterial infections in children

The Host-Pathogen Interaction in Cystic Fibrosis

edited by

Angela Sandri

, Caterina Signoretto and

Laura Veschetti

submission deadline 31 Jan 2026 | Viewed by 579 | Submission Open

Keywords: cystic fibrosis; respiratory infection; host– pathogen interaction; CFTR; immune system

Tick-Borne Encephalitis Virus: 2nd Edition

edited by

Anna Moniuszko-Malinowska

submission deadline 31 Jan 2026 | Viewed by 444 | Submission Open

Keywords: TBE; TBEV; tick; encephalitis; meningitis

XXth International Meeting on the Biology and Pathogenicity of Free-Living Amoebae (FLAM 2025)

edited by

Jacob Lorenzo-Morales

Ismael Castelan-Ramírez

José De Jesús Serrano-Luna

, Alvaro de Obeso Fernandez Del Valle, Fernando Lares-Villa and

Maritza Omaña-Molina

submission deadline 31 Jan 2026 | Viewed by 340 | Submission Open

Keywords: amoeba; Naegleria; Acanthamoeba; Balamuthia; Vermamoeba; free-living

(This special issue belongs to the Section Parasitic Pathogens)

Gut–Brain Axis in Neurodevelopment: Microbial Metabolites and Neurological Function

edited by

Xuesong Zhang

and

Ningning Li

submission deadline 31 Jan 2026 | Viewed by 336 | Submission Open

Keywords: microbiome; gut– brain axis; microbial metabolites; neurodevelopment; host– microbe interaction

Multidrug Resistance and the Microbiome in Cancer and Infectious Diseases

edited by

Zisis Kozlakidis

submission deadline 31 Jan 2026 | Viewed by 302 | Submission Open

Keywords: antimicrobial resistance (AMR); multidrug resistance (MDR); microbiome; cancer; infectious diseases; infectious disease pathogens; tumour; treatment response

New Insights into Antibiotic-Resistant Pathogens Within the One Health Framework: Epidemiology, Mechanisms and Strategies for Eradication

edited by

Uriel Alberto Angulo-Zamudio

, Vicente Adrián Canizalez-Román and

Nidia M. León-Sicairos

submission deadline 31 Jan 2026 | Viewed by 247 | Submission Open

Keywords: antibiotic resistance; pathogens; pandemic; epidemiology; one health

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Rat Lungworm Disease—Second Edition

edited by

Susan Jarvi

submission deadline 31 Jan 2026 | Viewed by 228 | Submission Open

Keywords: Angiostrongylus cantonensis; rat lungworm; neuroangiostrongyliasis; accidental hosts; parasitic nematode

(This special issue belongs to the Section Parasitic Pathogens)

Innovative Approaches to Antibody-Mediated Therapies for Infectious Diseases

edited by

Adinarayana Kunamneni

and

Yash Gupta

submission deadline 31 Jan 2026 | Viewed by 112 | Submission Open

Keywords: phage and ribosome display; display technologies; single-cell analysis and artificial intelligence (AI); recombinant antibody formats; humanization and affinity maturation; optimization; physiochemical properties; infectious diseases; prophylactic; therapeutic

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Biology, Epidemiology and Interactions of Parasitic Diseases

edited by

Dirceu Guilherme de Souza Ramos

and Hanstter Hallison Alves Rezende

submission deadline 1 Feb 2026 | 3 articles | Viewed by 4339 | Submission Open

Keywords: host– parasite interactions; parasitic diseases; vectors; parasites

(This special issue belongs to the Section Parasitic Pathogens)

Epidemiology and Molecular Diagnosis of Vector-Borne Diseases

edited by

Ricardo Parreira

Sandra Antunes

and

Ana Domingos

submission deadline 10 Feb 2026 | Viewed by 277 | Submission Open

Keywords: vector-borne diseases; molecular diagnostics; epidemiology; public health surveillance

(This special issue belongs to the Section Ticks)

Pathogenesis, Diagnosis, and Innovative Therapies in Clinical Infections

edited by Anna Gidari and

Elisabete Machado

submission deadline 10 Feb 2026 | Viewed by 224 | Submission Open

Keywords: clinical infections; infectious diseases; pathogenesis; diagnosis; therapies; antibiotic resistance

Lyme Disease: Celebrating the 40th Anniversary of the First Diagnostic Test of Lyme Disease

edited by András Lakos

submission deadline 10 Feb 2026 | Viewed by 160 | Submission Open

Keywords: lyme borreliosis; borrelia antibody testing; predictive value; testing serological progression and regression; how to prove cure of Lyme disease

Thinking Inside the Host: Strategies of Facultative Intracellular Bacteria

edited by

Cecilia Ambrosi

submission deadline 10 Feb 2026 | Viewed by 137 | Submission Open

Keywords: facultative intracellular bacteria; eukaryotic hosts; pathogens invade; pathogens persist; pathogens disseminate

(This special issue belongs to the Section Bacterial Pathogens)

Toxoplasmosis in Humans and Animals

edited by

Coralie L'Ollivier

and

Younes Laidoudi

submission deadline 10 Feb 2026 | Viewed by 119 | Submission Open

Keywords: Toxoplasma gondii; zoonosis; congenital toxoplasmosis; applied epidemiology; One Health; host– pathogen interaction; diagnostic methods; foodborne transmission

(This special issue belongs to the Section Parasitic Pathogens)

Understanding HIV Pathogenesis and Targeting for the Prevention and Cure

edited by

Saumya Anang

and

Karolina Akinosoglou

submission deadline 12 Feb 2026 | 2 articles | Viewed by 4240 | Submission Open

Keywords: HIV; AIDS; pathogenesis; treatment; antiretroviral drugs

(This special issue belongs to the Section Viral Pathogens)

Emerging and Re-Emerging Bacterial Infections

edited by

William S. Lawrence

submission deadline 15 Feb 2026 | 5 articles | Viewed by 15531 | Submission Open

Keywords: bacteria; human infection; emerging infections; pathogenesis; mutation; virulence; animal model of infection; antibiotic-resistance; immunity; therapeutics

(This special issue belongs to the Section Emerging Pathogens)

Bacterial Resistance and Novel Therapeutic Approaches

edited by

Longzhu Cui

, Shinya Watanabe and Hui-min Neoh

submission deadline 15 Feb 2026 | 3 articles | Viewed by 3610 | Submission Open

Keywords: antimicrobial resistance; bacteriophage therapy; novel antimicrobials; drug-resistant bacteria; biofilm disruption; innovative therapeutics; host– pathogen interaction

(This special issue belongs to the Section Bacterial Pathogens)

Viral Infections, Chronic Inflammation and Carcinogenesis

edited by

Angioletta Lasagna

and Davide Dalu

submission deadline 15 Feb 2026 | Viewed by 226 | Submission Open

Keywords: oncogenic virus; HPV; AIDS-related cancers; HCV; HBV; hit-and-run theory; vaccination

(This special issue belongs to the Section Viral Pathogens)

Bacterial Infections and Drug Resistance in Wildlife

edited by

Danny Fuentes-Castillo

submission deadline 15 Feb 2026 | Viewed by 91 | Submission Open

Keywords: virulence; antimicrobial resistance; wildlife; conservation; infectious diseases

(This special issue belongs to the Section Bacterial Pathogens)

New Advances in Plant–Virus Interactions

edited by

Hernan Garcia-Ruiz

submission deadline 15 Feb 2026 | Viewed by 83 | Submission Open

Keywords: plant-virus interactions; virus-virus interactions; virus pathogenesis; antiviral defense; virus evolution; genomic variation

(This special issue belongs to the Section Viral Pathogens)

Exploring the Epidemiology, Pathogenicity, and Therapeutic Options of Staphylococcus spp.: 2nd Edition

edited by

Francesca Paola Nocera

and

Patrizia Nebbia

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6237 | Submission Open

Keywords: Staphylococcus spp.; transmission; pathogenesis of infections; antibiotic resistance; methicillin resistance; therapy; zoonotic diseases; One Health

(This special issue belongs to the Section Bacterial Pathogens)

Surveillance, Detection and Control of Infectious Diseases of Bees

edited by

Nuria Morfin

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5093 | Submission Open

Keywords: bee pathogens; infectious diseases; pathogen surveillance; pathogenicity; host– pathogen interactions

Artificial Intelligence in Infectious Diseases: From Pathogen Recognition to Personalized Medicine

edited by

Giorgio Fedele

and

Annapina Palmieri

submission deadline 20 Feb 2026 | Viewed by 210 | Submission Open

Keywords: machine learning; infectious disease; artificial intelligence; immune responses; host-pathogen interactions

Malaria in a Changing World

edited by

Harry Tagbor

and

Luiz Shozo Ozaki

submission deadline 20 Feb 2026 | Viewed by 148 | Submission Open

Keywords: malaria; climate change; vector-borne disease; global health; drug resistance; health systems; technological innovation; epidemiological transition; social determinants of health; one health

(This special issue belongs to the Section Parasitic Pathogens)

Mycoplasmas in Respiratory Tract Infections of Cattle: 2nd Edition

edited by