Molecular Mechanisms and Ecological Interventions in Zoonotic Pathogens

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 31 May 2026 | Viewed by 284

Special Issue Editors


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Guest Editor
Department of Veterinary Public Health, College of Veterinary Medicine & Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, 61 Daizong Street, Tai'an City 271018, China
Interests: zoonotic bacterial diseases; host–pathogen interactions; immune evasion; live bacterium vector-based vaccines
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Guest Editor
National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
Interests: tuberculosis; pathology; innate immune response; gut; microbiota

E-Mail Website
Guest Editor
College of Veterinary Medicine & Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, 61 Daizong Street, Tai'an City 271018, China
Interests: air transmission; viruses; immune responses; interventions

Special Issue Information

Dear Colleagues,

Zoonotic pathogens, which are transmitted between animals and humans, pose significant threats to global health. Research in this field is focused on unraveling the molecular mechanisms underlying pathogen emergence, transmission, and host adaptation. Key areas include exploring viral/bacterial genomics to identify virulence factors, host–pathogen interactions (e.g., receptor binding and immune evasion), and the evolutionary dynamics driving cross-species spillover. Additionally, ecological interventions are designed to disrupt transmission cycles by targeting reservoir hosts, vectors, and environmental drivers. Current studies are exploring wildlife surveillance, habitat management, and One Health strategies incorporating human, animal, and environmental health data. By bridging molecular insights and ecological solutions, researchers hope to mitigate zoonotic threats through early detection, targeted vaccines/therapeutics, and sustainable ecosystem-based interventions. Collaborative, interdisciplinary efforts are critical in addressing the complex interplay among biological, environmental, and anthropogenic factors in zoonotic disease emergence. This Special Issue will highlight the complexity of zoonotic spillover, bridging molecular biology, ecology, and public health. It will advocate for One Health strategies to preempt outbreaks through integrated research and policy.

Dr. Fangkun Wang
Dr. Ruichao Yue
Dr. Ning Li
Guest Editors

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Keywords

  • zoonotic diseases
  • veterinary public health
  • foodborne
  • ecology diseases
  • pathogenesis
  • host–pathogen interactions
  • genomics
  • evolution
  • diagnosis
  • treatment
  • vaccine

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