Pathogenesis, Antibiotic Resistance, and Host Immune Responses to Bacterial Infections

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: 10 June 2026 | Viewed by 2

Special Issue Editor


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Guest Editor
State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China
Interests: bacterial pathogenesis; gene regulation; antibiotic resistance
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Special Issue Information

Dear Colleagues,

Bacterial infections remain a major global health burden, driven by the dual challenges of pathogen virulence and antimicrobial resistance. Understanding the mechanisms of bacterial pathogenesis, antibiotic resistance mechanisms, and host immune responses is critical to developing effective therapeutic and preventive strategies. This Special Issue, “Pathogenesis, Antibiotic Resistance, and Host Immune Responses to Bacterial Infections,” aims to highlight cutting-edge research that elucidates the following:

  1. How bacterial pathogens sense, manipulate, and damage host cells and tissues;
  2. The genetic, biochemical, and ecological drivers of antibiotic resistance acquisition and transmission;
  3. The innate and adaptive immune mechanisms that recognize and respond to invading bacteria.

We welcome studies exploring molecular mechanisms of virulence, antibiotic resistance, gene regulation, evolution of drug resistance, host immune responses and signaling pathways, as well as novel diagnostic or therapeutic approaches. By integrating multidisciplinary insights, this issue seeks to advance our ability to combat bacterial pathogens in an era of increasing antimicrobial resistance.

Prof. Dr. Weihui Wu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bacterial pathogenesis
  • antibiotic resistance
  • host immune responses
  • bacterial virulence
  • antimicrobial strategies

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Published Papers

This special issue is now open for submission.
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