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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Leishmaniasis: Current Status and Future Perspectives

edited by

Maria do Socorro Pires Cruz

and

Flávia de Oliveira Cardoso

submission deadline 15 Dec 2025 | 2 articles | Viewed by 11632 | Submission Open

Keywords: leishmaniasis; control; therapy; epidemiology; vector; genetics; immunotherapy; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention

edited by

Aldemir B. Oliveira-Filho

submission deadline 15 Dec 2025 | 5 articles | Viewed by 11098 | Submission Open

Keywords: epidemiology; diagnosis; prevention; control; access and care strategies

(This special issue belongs to the Section Viral Pathogens)

Advances in Animal Parasitic Diseases

edited by

Georgiana Deak

Lavinia Ciucǎ

and Harold Salant

submission deadline 15 Dec 2025 | 5 articles | Viewed by 8043 | Submission Open

Keywords: pet animals; parasites; exotic pets; zoo animals; parasitic diseases

(This special issue belongs to the Section Parasitic Pathogens)

New Insights in Viral Diseases and Computational Biology

edited by Xiaofeng Dong

submission deadline 15 Dec 2025 | 2 articles | Viewed by 3510 | Submission Open

Keywords: bioinformatics method/pipeline in virology; virus genome evolution; host transcriptome; virus and host interaction; bioinformatics in the design of antiviral drug and vaccines; machine learning in virology

(This special issue belongs to the Section Viral Pathogens)

Mycobacterial Infection: Pathogenesis and Drug Development

edited by

Joseph Oliver Falkinham

submission deadline 15 Dec 2025 | 3 articles | Viewed by 2662 | Submission Open

Keywords: mycobacteria; adaptation; phagocytic survival; drug-exposed recovery; resource diversion; dormancy; persisting cells

(This special issue belongs to the Section Bacterial Pathogens)

Leishmaniases: From Clinical Presentation, to Pathogenesis and Basic Science

edited by

Carlos Henrique Nery Costa

submission deadline 15 Dec 2025 | 2 articles | Viewed by 2214 | Submission Open

Keywords: leishmania infantum; leishmania donovani; visceral leishmaniasis; kala-azar; hemorrhages; HIV

(This special issue belongs to the Section Parasitic Pathogens)

Diagnostic Challenges in Joint Infections: From Culture to Molecular Techniques

edited by Jochen Hofstaetter

submission deadline 15 Dec 2025 | 1 articles | Viewed by 763 | Submission Open

Keywords: joint infections; molecular diagnostics; periprosthetic joint infections

Microbial Mechanisms and Host Interactions in Oral Diseases: Implications for Pathogenesis, Prevention, and Novel Therapeutics

edited by

Shankargouda B. Patil

submission deadline 15 Dec 2025 | Viewed by 312 | Submission Open

Keywords: oral diseases; dental caries; periodontal disease; microbial biofilms; innovative therapeutics

Bacterial Pathogens-Host Interface in Cystic Fibrosis

edited by

Roberto Rosales-Reyes

submission deadline 15 Dec 2025 | Viewed by 177 | Submission Open

Keywords: cystic fibrosis; bacterial pathogens; bacterial adaptation; bacterial pathogenesis; cell– host interaction; immune response; modulators effect; antimicrobial resistance

(This special issue belongs to the Section Bacterial Pathogens)

Advancements in Understanding and Managing Human Herpesvirus Infections and Diseases

edited by

Francesco Broccolo

and

Jing Wu

submission deadline 15 Dec 2025 | Viewed by 172 | Submission Open

Keywords: herpesviruses; antiviral therapies; immunopathogenesis; treatment; vaccine

(This special issue belongs to the Section Viral Pathogens)

Dynamics of Vector-Borne Infections

edited by Eduardo Massad

submission deadline 15 Dec 2025 | Viewed by 169 | Submission Open

Keywords: mathematical models; vector-borne infections; population dynamics

(This special issue belongs to the Section Viral Pathogens)

Pathogen–Host Interactions: Death, Defense, and Disease

edited by Hongyan Guo and Heather S. Koehler

submission deadline 20 Dec 2025 | 2 articles | Viewed by 7272 | Submission Open

Keywords: host– pathogen interaction; immune evasion; virulence factors; antimicrobial resistance; zoonosis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Understanding Microbial Keratitis: Basic Science, Epidemiology, Diagnosis and Management

edited by

Chameen Samarawickrama

, Vannessa Leung, Yashar Seyed Razavi and Samantha Bobba

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2464 | Submission Open

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

New Insights on Parasites as Bioindicators

edited by Jaqueline Bianque de Oliveira and Müller Ribeiro Andrade

submission deadline 20 Dec 2025 | Viewed by 502 | Submission Open

Keywords: parasitic ecology; habitat change; bioindicators; emerging infectious diseases; zoonoses; wildlife; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Epidemiology of Human Infectious Diseases During Health Crises in Low- and Middle-Income Countries

edited by

Samia Boussaa

and Youssef Ikken

submission deadline 20 Dec 2025 | Viewed by 216 | Submission Open

Keywords: epidemiology of infectious disease; COVID19; measles; tuberculosis; malaria; VIH; bacterial meningitis; infectious diseases; antibioresistance

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Host Interaction and Immune Modulation of RNA Viruses

edited by

Zhenlong Liu

and

Sonia Navas-Martin

submission deadline 22 Dec 2025 | 2 articles | Viewed by 3834 | Submission Open

Keywords: RNA viruses; viral immunology; antiviral therapy development

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Current Challenges in Veterinary Virology

edited by

Magdalena Materniak-Kornas

Marzena Rola-Łuszczak

and

Grzegorz Woźniakowski

submission deadline 31 Dec 2025 | 16 articles | Viewed by 43601 | Submission Open

Keywords: virus; veterinary; diagnostics; host interaction; epidemiology; evolution

(This special issue belongs to the Section Viral Pathogens)

New Insights into Viral Pathogenesis, Host Immune Responses and Immunotherapies

edited by

Dawei Zhou

, Taiwei Li and

Theresa Chang

submission deadline 31 Dec 2025 | 6 articles | Viewed by 13313 | Submission Open

Keywords: virus-host interaction; viral replication; viral pathogenesis; host immune responses; antiviral immunotherapies

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Emergence and Re-Emergence of Animal Viral Diseases

edited by

Zaheer Ahmed

submission deadline 31 Dec 2025 | 8 articles | Viewed by 10180 | Submission Open

Keywords: animal viral diseases; virus emergence; molecular characterization; novel assays; whole-genome sequencing (WGS); foreign animal diseases; disease surveillance and monitoring; pathogen evolution; diagnostic innovations; epidemiological trends

(This special issue belongs to the Section Emerging Pathogens)

Molecular Detection and Characterisation of Viral Pathogens: 2nd Edition

edited by

Armanda Bastos

and David P. Tchouassi

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5548 | Submission Open

Keywords: diversity; evolution; genomics; molecular diagnostics; molecular epidemiology; vaccines; vector-borne; virulence; zoonotic

(This special issue belongs to the Section Viral Pathogens)

Hepatitis E Virus (HEV) Infection Among Humans and Animals: Epidemiology, Clinical Characteristics, Treatment and Prevention—2nd Edition

edited by

Jelena Prpić

and

Magdalena Baymakova

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5296 | Submission Open

Keywords: seroprevalence; molecular analysis; clinical characteristics; prevention; treatment

(This special issue belongs to the Section Viral Pathogens)

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5125 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Host-Pathogen Interactions During Pathogenic Human Coronavirus Infection: 2nd Edition

edited by

Masfique Mehedi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5015 | Submission Open

Keywords: COVID-19; spike; mRNA; goblet cell; viremia; pneumonia; convalescent; antibody; transmission

(This special issue belongs to the Section Viral Pathogens)

Laboratory Diagnostics in Epidemiological Diseases Caused by Animal Pathogens

edited by

Tomasz Grenda

and

Karol Stasiak

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4998 | Submission Open

Keywords: animal pathogens; laboratory diagnostics; epidemiology; infections; toxins

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Covalent Inhibitors of Pathogenic Bacterial, Protozoal, Viral, and Fungal Targets

edited by

Monika I. Konaklieva

and Balbina J. Plotkin

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2984 | Submission Open

Keywords: covalent inhibitors; pathogenic bacterial and viral protein targets; protozoa; fragment-based drug discovery; chemical warheads; prodrugs; STD NMR; MS; SITE (single-injection thermal extinction)

One Health—Viral Zoonosis: Epidemiology, Pathogenesis, Surveillance and Early Warning, Novel Prevention and Control Technologies

edited by Xuejie Yu, Xuexing Zheng and Lina Yan

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2444 | Submission Open

Keywords: viral zoonoses; epidemiology; pathogenesis; surveillance; prevention and control technologies

(This special issue belongs to the Section Viral Pathogens)

HIV/AIDS Epidemiology, Prevention and Diagnostics: Current State of Research

edited by

Lars Henning

and Maria Castellanos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2379 | Submission Open

Keywords: HIV; AIDS; diagnostics; epidemiology; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Surveillance, Prevention and Control of Sexually Transmitted Infections

edited by

Miguel A. Sánchez-Alemán

submission deadline 31 Dec 2025 | Viewed by 956 | Submission Open

Keywords: sexually transmitted infections; syphilis; herpes; papillomavirus; HIV; sexual health; epidemiology; reproductive health; prevention; diagnosis; treatment

Understanding Emerging and Re-Emerging Viral Infections

edited by

Jose Angel Regla Nava

submission deadline 31 Dec 2025 | Viewed by 372 | Submission Open

Keywords: diagnosis; pathogenesis; evolution; epidemiology; drugs; vaccines

(This special issue belongs to the Section Viral Pathogens)

Multidrug-Resistant Microorganisms’ (MDROs) Genomic Characteristics Integrated with Serum Biomarkers Measurement in the Diagnosis and Prognosis of Severe Infectious Disease as Sepsis

edited by

Silvia Spoto

and

Silvia Angeletti

submission deadline 31 Dec 2025 | Viewed by 365 | Submission Open

Keywords: procalcitonin (PCT); mid-regional-pro-adrenomedullin (MR-proADM); multidrug-resistant microorganisms (MDRO); active surveillance cultures (ACS); healthcare-associated infections (HCAIs)

Monitoring and Management of Mosquito-Borne Pathogens in Mosquito Populations

edited by

Bethany Bolling

and Hannah Romo

submission deadline 31 Dec 2025 | Viewed by 361 | Submission Open

Keywords: mosquitoes; arboviruses; surveillance; mosquito collection; mosquito testing; integrated mosquito management; mosquito control; response plans; outbreak response

Advances in Chlamydia-Related Diseases

edited by

Katalin Burián

submission deadline 31 Dec 2025 | Viewed by 266 | Submission Open

Keywords: chlamydia; pathomechanism; host interaction; host-specific immunity; in vitro persistence model; epidemiology; treatment; vaccination

(This special issue belongs to the Section Bacterial Pathogens)

Emerging Trends in Arbovirus Research: Diagnosis, Transmission, and Therapeutic Development

edited by

Paulo Ricardo da Silva Sanches

submission deadline 31 Dec 2025 | Viewed by 239 | Submission Open

Keywords: arboviruses; vector-borne diseases; viral pathogenesis; molecular diagnostics; antiviral therapies; vaccine develop-ment; vector control; infectious diseases

(This special issue belongs to the Section Viral Pathogens)

Current Research on Plant–Pathogen Interactions

edited by Ana Rita Varela and

Hon Ho

submission deadline 31 Dec 2025 | Viewed by 228 | Submission Open

Keywords: plant– microbe interactions; plant immunity; biotechnological innovations in crop protection; pathogen virulence strategies

Diagnosis of Tuberculosis and Mycobacteriosis—Focus on Extrapulmonary Forms

edited by Jacobus H. de Waard

submission deadline 31 Dec 2025 | Viewed by 160 | Submission Open

Keywords: molecular diagnostics; imaging innovations; biomarker discovery; AI applications

(This special issue belongs to the Section Bacterial Pathogens)

Influenza A Virus: Updates and Insights

edited by

Pawel Zmora

and

Elzbieta Kierzek

submission deadline 10 Jan 2026 | 1 articles | Viewed by 3411 | Submission Open

Keywords: influenza A virus; virus– host interactions; antivirals; vaccines; epidemiology; genetic diversity; RNA structure; RNA interactions; structural biology

(This special issue belongs to the Section Viral Pathogens)

The Dark Side of Fungi: Exploring Pathogenesis in Candida and Other Fungal Pathogens

edited by

Bruna Gonçalves

Stephen A. Klotz

and

Ana V. Espinel-Ingroff

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2808 | Submission Open

Keywords: fungal pathogenesis; Candida species; virulence factors; fungi– host interaction; immune evasion; antifungal resistance

(This special issue belongs to the Section Fungal Pathogens)

Molecular and Cellular Research on Targets for Antimalarial Therapy Development

edited by

Sanjay Arvind Desai

submission deadline 15 Jan 2026 | 1 articles | Viewed by 1853 | Submission Open

Keywords: malaria; molecular biology; cellular biology; antimalarial drug discovery and development; malaria vaccines

(This special issue belongs to the Section Parasitic Pathogens)

Pathogens in Dentistry: Diversity, Virulence, Resistance, and Control

edited by

Gláuber Campos Vale

submission deadline 15 Jan 2026 | Viewed by 176 | Submission Open

Keywords: oral pathogens; biofilm; dental caries; periodontitis; virulence factors; antimicrobial resistance; microbiome; infection control; molecular diagnostics; host immunity

Biomarkers and Diagnostic Advances in Oral Pathogen Detection: Exploring Microbial Diversity and Clinical Applications

edited by

Aleksandar Jakovljevic

submission deadline 15 Jan 2026 | Viewed by 140 | Submission Open

Keywords: oral pathogens; biomarkers; diagnostic methods; microbial diversity; personalized medicine

New Insights into Rickettsia and Related Organisms

edited by

Alison Luce-Fedrow

and Kristin E. Mullins

submission deadline 20 Jan 2026 | 5 articles | Viewed by 8430 | Submission Open

Keywords: Rickettsia; Orientia; Ehrlichia; Anaplasma; Coxiella; Borrelia; Bartonella; Babesia

(This special issue belongs to the Section Bacterial Pathogens)

Hand–Foot–Mouth Disease

edited by

Kow-Tong Chen

submission deadline 20 Jan 2026 | 2 articles | Viewed by 5998 | Submission Open

Keywords: hand– foot– mouth disease; Coxsackie virus; epidemiology; pathogenesis; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Updates on Animal Papillomaviruses

edited by

Francesca De Falco

and Franco Roperto

submission deadline 20 Jan 2026 | 2 articles | Viewed by 4738 | Submission Open

Keywords: papillomavirus; trans-species transmission; environmental contamination

(This special issue belongs to the Section Viral Pathogens)

Current Research on Bacillus anthracis Infection

edited by Viviana Manzulli and

Domenico Galante

submission deadline 20 Jan 2026 | 2 articles | Viewed by 4062 | Submission Open

Keywords: Bacillus anthracis; epidemiology; pathogenesis; diagnostics; genomics

(This special issue belongs to the Section Bacterial Pathogens)

Immune Pathways and Mechanisms Involved in Viral Infections

edited by

Celina Monteiro Abreu

, Lendel Correia Da Costa, Ana Carolina Soares and

Isadora Alonso Corrêa

submission deadline 20 Jan 2026 | 1 articles | Viewed by 918 | Submission Open

Keywords: viral infections; host– virus interactions; immune pathways; viral evasion; antiviral therapies; vaccine development

(This special issue belongs to the Section Viral Pathogens)

Emerging and Neglected Zoonotic Pathogens in Companion Animals

edited by Olga Szalus̈-Jordanow

submission deadline 20 Jan 2026 | 1 articles | Viewed by 644 | Submission Open

Keywords: zoonotic pathogens; host– pathogen interactions; companion animals; one Health; antimicrobial resistance; emerging infectious diseases; interspecies transmission; molecular epidemiology; pathogen surveillance

(This special issue belongs to the Section Emerging Pathogens)

Genomic Applications in Microbial Adaptation, Antimicrobial Resistance and One Health Perspectives

edited by

Wellington Rodrigues

Aristóteles Góes-Neto

and Siomar de Castro Soares

submission deadline 20 Jan 2026 | Viewed by 255 | Submission Open

Keywords: genomics; One Health; antimicrobial resistance; pathogen evolution; metagenomics; reverse vaccinology; zoonotic diseases; mobilome; genomic surveillance; predictive modeling

Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes: 2nd Edition

edited by

Antonella Marangoni

and

Claudio Foschi

submission deadline 25 Jan 2026 | 3 articles | Viewed by 9320 | Submission Open

Keywords: vaginal microbiome; vaginal metabolome; lactobacilli; host– pathogen interactions; sexually transmitted infections; Chlamydia; gonorrhea; vaginal dysbiosis; vulvovaginal candidiasis; animal models

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Leveraging Technological Advancement for Pandemic Preparedness

edited by Kai Sen Tan,

Chee Keng MOK

Yaw Shin Ooi

, Chee Wah Tan,

Mookkan Prabakaran

, Dahai Luo and Poying Chia

submission deadline 25 Jan 2026 | 2 articles | Viewed by 3498 | Submission Open

Keywords: pandemic preparedness; disease X; technological platforms; treatment and prevention; viral infectious diseases

New Insights Into Zoonotic Intracellular Pathogens

edited by

Tarka Raj Bhatta

, Stephen Graves and

John Stenos

submission deadline 25 Jan 2026 | 2 articles | Viewed by 2917 | Submission Open

Keywords: zoonotic intracellular pathogens; bacteria; viruses; sequencing; virulence factors; immune system; vaccine development; diagnostic tools; one health

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