Detection, Transmission, and Diagnosis of Animal Viruses: A One Health Approach

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".

Deadline for manuscript submissions: 15 May 2026 | Viewed by 669

Special Issue Editor


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Guest Editor
Laboratorio de Virología, Centro de Microbiología Básica y Aplicada, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata CP 1900, Argentina
Interests: virology; viral pathogeny; cell cultures; veterinary; viral replication
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Special Issue Information

Dear Colleagues,

In the present day, rural residents have a plethora of opportunities for advancement that were unavailable in previous decades. A similar phenomenon is observed in the world of viruses. Humans explore and colonize previously unexplored habitats, which also allows for interaction with viral species that have the potential to establish a new and casual infections through this contact.

Whether through travel, tourism, or the domestication of unconventional animals, humans have increased their exposure to numerous viral species with which they had minimal or no prior interaction.

The survey of diverse viral diseases facilitates the comprehension of viral dispersion dynamics and the epidemiology of viruses in this novel environment. This understanding is imperative for the development of effective health management strategies for both animals and humans.

Dr. Germán Ernesto Metz
Guest Editor

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Keywords

  • animal viruses
  • One Health
  • diagnosis
  • survey
  • viral detection

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Published Papers (1 paper)

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Research

13 pages, 1874 KB  
Article
Evidence of Wild Boars as a Reservoir of Zoonotic Hepatitis E Virus Genotype 3: Implications for Public Health in Argentina
by Macarena Marta Williman, Santiago Emanuel Colina, Guadalupe Di Cola, Diana Sofia Ozaeta, Bruno Nicolás Carpinetti, María Belén Pisano, Viviana Elizabeth Ré, María Soledad Serena, María Gabriela Echeverría and Germán Ernesto Metz
Pathogens 2026, 15(2), 205; https://doi.org/10.3390/pathogens15020205 - 12 Feb 2026
Viewed by 505
Abstract
Hepatitis E virus (HEV) is a global public health concern, causing over 20 million infections annually. It is primarily transmitted via the fecal–oral route, with wild boars and domestic swine as major reservoirs involved in zoonotic transmission. Bahía de Samborombón is an important [...] Read more.
Hepatitis E virus (HEV) is a global public health concern, causing over 20 million infections annually. It is primarily transmitted via the fecal–oral route, with wild boars and domestic swine as major reservoirs involved in zoonotic transmission. Bahía de Samborombón is an important natural reserve in Argentina characterized by a high population of wild boars, located in a livestock-intensive region near major urban centers. As part of a wild boar control program, 11 sampling campaigns were carried out between 2022 and 2023. Fecal, blood, and liver samples were systematically collected from 80 captured animals for the detection and characterization of HEV through antibody and RNA testing. Serological analysis revealed a positivity rate of 42.4%, whereas RT-qPCR detected HEV RNA in 9.1% of fecal samples and 12.5% of liver samples. From the positive samples, seven viral sequences were recovered using RT-nested PCR, including six from ORF1 and one from ORF2. Phylogenetic analysis clustered these sequences within zoonotic HEV genotype 3, showing a close relationship with human sequences from Buenos Aires and neighboring provinces. This study confirms the presence of HEV in wild boars from Argentina, highlighting the circulation of genotype 3, clade abchijklmno and the associated zoonotic risk. Full article
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