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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Molecular Epidemiology and Innovative Diagnostic Strategies for Infectious Disease Control

edited by

Ko Ko

, Inn Kynn Khaing and

Zayar Phyo

submission deadline 31 Jul 2026 | Viewed by 45 | Submission Open

Keywords: elimination; eradication; surveillance; diagnostics; screening; epidemiology; pathogens; outbreaks; genomics; sequencing; CRISPR; point-of-care; modelling; innovation; preparedness

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Innovative Anti-Toxoplasma Strategies: Pharmacology and Drug Development

edited by

Chunmei Jin

submission deadline 31 Jul 2026 | Viewed by 37 | Submission Open

Keywords: Toxoplasma gondii; drug discovery; pharmacology; antiparasitic agents; drug repurposing; novel therapeutics; toxoplasmosis; pharmacokinetics; drug resistance

(This special issue belongs to the Section Parasitic Pathogens)

From Animal Health to Public Health: Eco-Epidemiological Pathways of Neglected Tropical Diseases

edited by Gina Polo

submission deadline 31 Jul 2026 | Viewed by 37 | Submission Open

Keywords: neglected tropical diseases; eco-epidemiology; climate change; vector dynamics; host– vector interactions; environmental drivers; public health; community-based research

Antimicrobial Resistance in Klebsiella pneumoniae

edited by

Eduardo Rodriguez-Noriega

and

Dolores Alcantar-Curiel

submission deadline 31 Jul 2026 | Viewed by 21 | Submission Open

Keywords: Klebsiella pneumoniae; multidrug resistant; ESKAPE pathogen; carbapenem resistant; hypervirulent

(This special issue belongs to the Section Bacterial Pathogens)

Porcine/Farm Animal Respiratory Pathogens: Pathogenesis, Diagnostics and Antimicrobial Resistance

edited by

Andrei Ungur

and

Levon Abrahamyan

submission deadline 31 Jul 2026 | Viewed by 20 | Submission Open

Keywords: porcine respiratory pathogens; pathogenesis; diagnostic methods; antimicrobial resistance; swine health management; respiratory disease complex; farm animal pathogens; surveillance and molecular epidemiology; one health

Molecular Mechanisms of Stress Adaptation in Foodborne Pathogens

edited by

Mohamed K. Fakhr

and

Anand B. Karki

submission deadline 31 Jul 2026 | Viewed by 13 | Submission Open

Keywords: foodborne pathogens; stress adaptation; molecular mechanisms; genomics; transcriptomics; gene expression

Swine Infectious Diseases: Diagnostics, Pathogenesis, and Control Strategies

edited by

Luis G. Gimenez-Lirola

Jeffrey J. Zimmerman

and

Jesús Hernández

submission deadline 10 Aug 2026 | 7 articles | Viewed by 9992 | Submission Open

Keywords: swine; infectious diseases of swine; swine pathogens; diagnostics; pathogenesis; immune response; control strategies; surveillance; vaccines

Emerging and Re-Emerging Avian Influenza Viruses in Wildlife

edited by

Klaudia Chrzastek

submission deadline 10 Aug 2026 | 3 articles | Viewed by 7059 | Submission Open

Keywords: avian influenza virus; HPAIV; LPAIV; wildlife; surveillance; epidemiology; phylogenetics; next-generation sequencing

(This special issue belongs to the Section Viral Pathogens)

Pathogenic Escherichia coli: Mechanisms of Virulence, Antimicrobial Resistance and Public Health Implications

edited by

Bogdan Nowicki

submission deadline 10 Aug 2026 | 1 articles | Viewed by 2584 | Submission Open

Keywords: pathogenic Escherichia coli; virulence factors; antimicrobial resistance; gastrointestinal infections; public health

(This special issue belongs to the Section Bacterial Pathogens)

Immune Pathways and Mechanisms Involved in Viral Infections

edited by

Celina Monteiro Abreu

, Lendel Correia Da Costa, Ana Carolina Soares and

Isadora Alonso Corrêa

submission deadline 10 Aug 2026 | 1 articles | Viewed by 1012 | Submission Open

Keywords: viral infections; host– virus interactions; immune pathways; viral evasion; antiviral therapies; vaccine development

(This special issue belongs to the Section Viral Pathogens)

Laboratory Diagnostics in Epidemiological Diseases Caused by Animal Pathogens

edited by

Tomasz Grenda

and

Karol Stasiak

submission deadline 15 Aug 2026 | 2 articles | Viewed by 5376 | Submission Open

Keywords: animal pathogens; laboratory diagnostics; epidemiology; infections; toxins

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Antiviral Strategies Against Mpox

edited by Julia Tree, Amanda Horton, David Ulaeto, Isobel Stokes and Amanda Phelps

submission deadline 15 Aug 2026 | Viewed by 123 | Submission Open

Keywords: Mpox virus; antiviral; vaccine; medical countermeasure; therapeutic; public health

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Advanced Antimicrobial Agents: Combatting Multi-Drug Resistant Bacterial Infections

edited by Nachiket Vaze

submission deadline 20 Aug 2026 | 5 articles | Viewed by 12038 | Submission Open

Keywords: multi-drug resistance; antimicrobial susceptibility; nanoformulations; UV disinfection; antibiotic synergy

(This special issue belongs to the Section Bacterial Pathogens)

Coxiella burnetii: The Host Immune Response, Host-Pathogen Interaction and Pathogenesis

edited by

Guoquan Zhang

and Erin J. Van Schaik

submission deadline 20 Aug 2026 | 3 articles | Viewed by 5453 | Submission Open

Keywords: Coxiella burnetii; host immune responses; host– Coxiella interaction; vaccine development; pathogenesis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Emerging and Neglected Zoonotic Pathogens in Companion Animals

edited by Olga Szalus̈-Jordanow

submission deadline 20 Aug 2026 | 1 articles | Viewed by 822 | Submission Open

Keywords: zoonotic pathogens; host– pathogen interactions; companion animals; one Health; antimicrobial resistance; emerging infectious diseases; interspecies transmission; molecular epidemiology; pathogen surveillance

(This special issue belongs to the Section Emerging Pathogens)

Pathogen-Integrated Non-Coding Sequences: Regulatory Roles in Infection, Immune Response, and Disease

edited by

Xiao-Ou Zhang

submission deadline 20 Aug 2026 | Viewed by 307 | Submission Open

Keywords: non-coding sequences; pathogen genome integration; immune response; lymphocyte subpopulations; diagnostic biomarkers; tuberculosis; HPV-related cancers; cervical cancer; pathogen-associated cancers; infectious diseases

The Oral-Systemic Microbiome Axis: From Local Dysbiosis to Multi-Organ Disease Pathogenesis

edited by

David R. Drake

submission deadline 20 Aug 2026 | Viewed by 22 | Submission Open

Keywords: oral microbiome; dysbiosis; microbial diversity; pathobiont; commensal bacteria; oral biofilm; periodontitis; dental caries; oral cancer; gingivitis; cardiovascular disease; diabetes; Alzheimer's disease; rheumatoid arthritis; cancer; obesity; 16S rRNA sequencing; metagenomics; metabolomics; machine learning; biomarkers; oral– systemic health; dentistry; cardiology; neurology; gastroenterology; precision medicine

One Health—Viral Zoonosis: Epidemiology, Pathogenesis, Surveillance and Early Warning, Novel Prevention and Control Technologies

edited by Xuejie Yu, Xuexing Zheng and Lina Yan

submission deadline 30 Aug 2026 | 2 articles | Viewed by 2734 | Submission Open

Keywords: viral zoonoses; epidemiology; pathogenesis; surveillance; prevention and control technologies

(This special issue belongs to the Section Viral Pathogens)

Tick-Borne Pathogens: Advanced Identification, Characterization, Transmission, and Prevalence Studies

edited by

Sara Savić

submission deadline 31 Aug 2026 | 5 articles | Viewed by 10875 | Submission Open

Keywords: ticks; tick-borne pathogens; identification; characterization; transmission; prevalence; host interactions; zoonoses

(This special issue belongs to the Section Ticks)

Pathogenesis, Epidemiology, and Control of Animal Influenza Viruses—2nd Edition

edited by Christina M. Leyson and

Silvia Carnaccini

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4859 | Submission Open

Keywords: avian influenza; swine influenza; equine influenza; animal influenza; influenza epidemiology; pathogenesis; influenza vaccines; influenza phylogenetics.

(This special issue belongs to the Section Viral Pathogens)

Parasitic Diseases in Livestock: Advances in Diagnostics, Understanding and Control

edited by

César Cristiano Bassetto

and Ana Cláudia Alexandre de Albuquerque

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2511 | Submission Open

Keywords: gastrointestinal nematodes; livestock; parasitic diseases; parasites; sheep; cattle; host– parasite interaction

(This special issue belongs to the Section Parasitic Pathogens)

Human Cytomegalovirus: From Molecular Pathogenesis to Therapeutic Innovations

edited by

Gaëtan Ligat

and Alexia Damour

submission deadline 31 Aug 2026 | 3 articles | Viewed by 1646 | Submission Open

Keywords: human cytomegalovirus; therapeutic strategies and vaccines; glioblastoma; congenital infection; immunocompromised

(This special issue belongs to the Section Viral Pathogens)

HIV Reservoir Dynamics and Latency Mechanisms Under Current and Emerging Antiviral Strategies

edited by

Chen Zhang

and

Prasanta K. Dash

submission deadline 31 Aug 2026 | Viewed by 261 | Submission Open

Keywords: HIV reservoirs; HIV latency mechanisms; reservoir persistence; reservoir dynamics prediction; HIV therapies; reservoir targeting; reservoir eradication strategies; new gene-editing delivery vehicles

(This special issue belongs to the Section Viral Pathogens)

From Acute Infection to Chronic Sequelae: A Research Trajectory in Viral Infections Disease Management

edited by

Olga Adriana Caliman-Sturdza

and

Roxana Gheorghita

submission deadline 31 Aug 2026 | Viewed by 218 | Submission Open

Keywords: viral pathogenesis; post-acute infection syndromes; chronic sequelae; long-term outcomes; disease management

(This special issue belongs to the Section Viral Pathogens)

Regulation of Host Innate Immunity During Pathogens Infection

edited by

Xin Ran

submission deadline 31 Aug 2026 | Viewed by 98 | Submission Open

Keywords: pathogens; bacterial pathogens; pattern-recognition receptors; innate immune circuits; gram-negative and gram-positive infections; inflammasome activation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Host–Microbiota Interactions in Periodontal Disease: Pathogenic Invasion, Immune Evasion, and Commensal Defense

edited by

Giancarlo A. Cuadra

and

Dominic L. Palazzolo

submission deadline 31 Aug 2026 | Viewed by 53 | Submission Open

Keywords: oral commensal streptococci; oral pathogens; oral epithelial tissues; pathogenic invasion; host defense; immune evasion; periodontal disease; external factors associated with periodontal disease; therapeutic strategies for periodontal disease

Immunopathogenesis of Influenza and Respiratory Syncytial Virus Infection

edited by

Norbert J. Roberts, Jr.

submission deadline 10 Sep 2026 | 2 articles | Viewed by 4346 | Submission Open

Keywords: influenza virus; respiratory syncytial virus; viral pathogenesis; monocytes– macrophages; lymphocytes

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Epidemiology, Diagnostics, and Therapeutics of High-Risk Human Papillomavirus (HPV) Infections

edited by Zhengchun Lu and Guang Fan

submission deadline 10 Sep 2026 | Viewed by 79 | Submission Open

Keywords: high-risk HPV; HPV-associated diseases; screening and diagnostics; HPV epidemiology; therapeutic and preventive strategies

(This special issue belongs to the Section Viral Pathogens)

Viral Infection and Antiviral Drug

edited by Hiya Lahiri and

Jochen Bodem

submission deadline 10 Sep 2026 | Viewed by 43 | Submission Open

Keywords: viral diseases; structural analysis; antivirals; artificial intelligence

(This special issue belongs to the Section Viral Pathogens)

Discovery of Novel Antiprotozoal Agents: Current Status and Future Perspectives

edited by

Klinger Antonio da Franca Rodrigues

submission deadline 15 Sep 2026 | 1 articles | Viewed by 172 | Submission Open

Keywords: neglected tropical diseases; drug discovery; natural products; medicinal chemistry

(This special issue belongs to the Section Parasitic Pathogens)

Pathogen–Host Interactions: Death, Defense, and Disease

edited by Hongyan Guo and Heather S. Koehler

submission deadline 20 Sep 2026 | 4 articles | Viewed by 8782 | Submission Open

Keywords: host– pathogen interaction; immune evasion; virulence factors; antimicrobial resistance; zoonosis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 20 Sep 2026 | 4 articles | Viewed by 6389 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Hepatitis Research: Current Trends

edited by

Wenyu Lin

submission deadline 21 Sep 2026 | Viewed by 103 | Submission Open

Keywords: hepatitis; liver disease; viral infection; antiviral therapy; vaccine development; immunopathogenesis; public health

Nosocomial Infections and Antimicrobial Resistance: Challenges and Solutions

edited by

Juan Manuel Bello-López

and

Miguel Ángel Loyola-Cruz

submission deadline 30 Sep 2026 | 4 articles | Viewed by 7097 | Submission Open

Keywords: nosocomial infections; antimicrobial resistance; molecular epidemiology; genomic surveillance; ESKAPE bacteria

(This special issue belongs to the Section Bacterial Pathogens)

Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications

edited by

Giuseppe Pipitone

Alberto Enrico Maraolo

and

Luigi Principe

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5533 | Submission Open

Keywords: antibiotics; multi-drug-resistant microorganisms; difficult-to-treat infections

(This special issue belongs to the Section Bacterial Pathogens)

Pediatric Viral Infections: Epidemiology, Treatment, and Emerging Challenges

edited by

Maria Pokorska-Śpiewak

and Magdalena Rutkowska

submission deadline 30 Sep 2026 | 5 articles | Viewed by 5058 | Submission Open

Keywords: pediatric infectious diseases; viral infections; viral hepatitis; COVID-19; HIV; mother-to-child transmission; vaccines

(This special issue belongs to the Section Viral Pathogens)

Emerging Viral Pathogens: Diagnosis, Treatment, and Public Health Interventions

edited by

Jasper Fuk-Woo Chan

and Vivian Huiping Shuai

submission deadline 30 Sep 2026 | 4 articles | Viewed by 2819 | Submission Open

Keywords: virus discovery; pathogenesis; antivirals; diagnostics; vaccines; public health

(This special issue belongs to the Section Emerging Pathogens)

Advancing Vaccine Strategies and Technologies for Controlling Swine Infectious Diseases

edited by

Jishu Shi

and

Lihua Wang

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2685 | Submission Open

Keywords: autogenous vaccines; swine infectious diseases; adjuvants; diagnostics; swine veterinarian

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Dairy Cattle Health: Mastitis, Milk Quality, and Antimicrobial Resistance from a One Health Perspective

edited by

Alfonso Zecconi

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2587 | Submission Open

Keywords: udder immune defenses; inflammation; milk leukocytes; mastitis control; One Health approach; immune components in milk

(This special issue belongs to the Section Bacterial Pathogens)

From Gastroenteritis to Emerging Threats: One Health Surveillance of Viral Infections

edited by

Adriana Luchs

and

Natalia Coelho Couto de Azevedo Fernandes

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2122 | Submission Open

Keywords: viral gastroenteritis; pathology of viral infections; fecal-borne diseases; one Health; interspecies transmission; molecular epidemiology; zoonotic viruses; environmental surveillance; foodborne and waterborne pathogen

(This special issue belongs to the Section Viral Pathogens)

Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

edited by

Marcia Aparecida Speranca

and

Aline Diniz Cabral

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1477 | Submission Open

Keywords: parasitic infectious diseases; eco-epidemiology; diagnosis; treatment; clinical management; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Vector-Borne Diseases and Transboundary Zoonoses: A One Health Perspective

edited by

Rafael Felipe da Costa Vieira

and

Richard de Campos Pacheco

submission deadline 30 Sep 2026 | 1 articles | Viewed by 848 | Submission Open

Keywords: zoonoses; one health approach; vector control; pathogen transmission; animal reservoirs; emerging infectious diseases; veterinary medicine; disease surveillance; epidemiology

Innate Immune Response and Pathogen Dynamics

edited by Guido Sireci

submission deadline 30 Sep 2026 | 2 articles | Viewed by 677 | Submission Open

Keywords: complement; natural killer; phagocytosis; DNA extracellular traps release

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Aquatic Pathogens and Host Immune Responses

edited by

Patricia Pereiro

submission deadline 30 Sep 2026 | 1 articles | Viewed by 641 | Submission Open

Keywords: aquaculture; diseases; immunity; vaccines; treatments

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Malaria: Updates on Prevention, Diagnosis, and Treatment

edited by Temi Lampejo and

Andrew Taylor-Robinson

submission deadline 30 Sep 2026 | Viewed by 443 | Submission Open

Keywords: malaria; plasmodium; prevention; vaccines; therapeutics

(This special issue belongs to the Section Parasitic Pathogens)

Encephalomyocarditis—Latest Insights

edited by Leonor Camacho-Sillero and

Jaco Bakker

submission deadline 30 Sep 2026 | Viewed by 93 | Submission Open

Keywords: encephalomyocarditis virus; ECMV; infecious disease; zoonotic disease; emerging pathogen

(This special issue belongs to the Section Viral Pathogens)

Microbial Interactions in Ticks: Pathogen–Pathogen and Pathogen–Non-Pathogenic Microorganism Dynamics in Coinfections

edited by

Elianne Piloto-Sardiñas

, Islay Rodríguez and

Huarrisson Azevedo Santos

submission deadline 30 Sep 2026 | Viewed by 90 | Submission Open

Keywords: tick-borne pathogens; microbial interactions; tick-borne coinfection; microbiome; vector competence

(This special issue belongs to the Section Ticks)

Pseudovirus-Based Strategies for Understanding and Controlling Viral Infections

edited by

Jianhui Nie

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2145 | Submission Open

Keywords: pseudovirus; infectivity; neutralization; antigenicity; immunogenicity

(This special issue belongs to the Section Viral Pathogens)

Antimicrobial Resistance and Pathogen Surveillance in Aquaculture

edited by Roberto Cruz-Flores and Karla Camacho

submission deadline 31 Oct 2026 | Viewed by 37 | Submission Open

Keywords: antimicrobial resistance (AMR); pathogen surveillance; aquaculture; environmental surveillance; bacterial infections; viral infections; fungal infections

Emerging Pathogenic Bacteria and Phage Therapy

edited by