Design and Synthesis of Antimicrobial and Antiviral Agents: From Molecular Targets to Therapeutic Strategies
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 40
Special Issue Editor
Interests: organic synthesis; medicinal chemistry; drug design; antimicrobial; antiviral; materials science; reaction mechanism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will highlight innovative approaches in the discovery and development of novel antimicrobial and antiviral agents, with an emphasis on structure-based drug design and mechanism-driven therapeutic strategies. We invite contributions covering the following areas:
- Rational Drug Design Approaches
- Target identification and validation.
- Structure–activity relationship (SAR) optimization.
- Fragment-based and computational drug design.
- Innovative Synthetic Methodologies
- Novel synthetic routes for bioactive compounds.
- Green chemistry approaches in antimicrobial synthesis.
- Multicomponent reactions for scaffold diversification.
- Mechanistic Studies and Resistance Solutions
- Mode-of-action investigations.
- Strategies with which to overcome drug resistance.
- Synergistic combination therapies.
- Translational Potential
- Lead compound optimization.
- ADMET property enhancement.
- Repurposing existing drugs for new indications.
We welcome original research articles, comprehensive reviews, and short communications that bridge molecular discovery with therapeutic applications.
Dr. Sameh Abdelwahed
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antimicrobial drug discovery
- antiviral agents
- structure-based design
- resistance mechanisms
- medicinal chemistry
- target identification
- lead optimization
- synthetic methodology
- mechanism of action
- therapeutic strategies
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