Recent Advances in Synthesis of Antiviral Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 1649
Special Issue Editors
Interests: drug design; antiviral agents; anticancer; antiparasitic
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; drug discovery; antiviral; anticancer; antiprotozoal
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Viruses are responsible for challenging diseases in humans representing important causes of morbidity and mortality worldwide. Despite the prominent efforts devoted in the development of antiviral agents, the current therapeutic options are still inadequate to contrast and produce a definitive cure for the disparate viral diseases. These limits, which have been dramatically underlined by the recent COVID-19 pandemic, are further highlighted from the diffusion of emerging viral diseases, for which effective therapeutics are lacking. In addition, widespread resistant viral strains are another critical issue that limits the efficacy of the current drugs, underlining the urgent need to develop new, effective, and more tolerated antiviral agents. Increasing efforts have been devoted to the search of antiviral agents modulating alternative biological target(s) and exploiting innovative mechanisms of action, allowing the identification of prominent and innovative antiviral agents in recent years.
This Special Issue aims to collect the most recent research devoted to the identification of new antiviral agents for the treatment of viral diseases, with major focus on the design, synthesis, and biological evaluation of small-molecule compounds. In this Special Issue, we are inviting original research articles, as well as review articles, which are related to the search of antiviral agents. Furthermore, we also welcome the submission of mechanistic studies of new small organic molecules, natural products, and chemical probes as well as in silico design of antiviral agents and antiviral target validation.
We look forward to receiving your contributions.
Prof. Roberta Costi
Dr. Francesco Saccoliti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antiviral
- drug design
- medicinal chemistry
- antiviral small molecules
- synthesis
- synthetic drugs
- antimicrobial
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