Recent Advances in the Synthesis and Structural Elucidation of Bioactive Lipid Mediators
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 17
Special Issue Editors
Interests: organic chemistry; medicinal chemistry; natural products chemistry; total synthesis; analytical chemistry; mass spectrometry; bioactive lipid mediators; spectroscopy; stereoselective synthesis; catalysis; biosynthesis; biogenic synthesis; lipidomics
Special Issues, Collections and Topics in MDPI journals
2. Immunology Program and Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore 117456, Singapore
Interests: pro-resolving lipid mediators; resolution of inflammation; innate immun-ity; efferocytosis; granulocyte trafficking; respiratory diseases; im-munopharmacology; natural products; targeted lipidomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the mid 1930s, von Euler discovered a potent biological substance from seminal vesicles that caused contraction of smooth muscle. This material, which would take almost three decades to be isolated in pure form for the first time by Bergström, was termed prostaglandin. Since the original disclosure of prostaglandins, an impressive body of research on the chemistry and biology of related bioactive substances has been published. These products display a wide range of actions and are involved in innate immunity, cell signaling, inflammation, and other important biochemical processes. Advances in the synthesis and biological understanding of these potent structures produced from polyunsaturated fatty acids (PUFAs) have enabled significant discoveries which have led to the development of novel therapeutic strategies. The role that chemistry has played in the total synthesis and structural elucidation of these naturally occurring compounds as well as their analogs is highly critical.
In this Special Issue of Molecules, titled Recent Advances in the Synthesis and Structural Elucidation of Bioactive Lipid Mediators, it is our intention to highlight the most up-to-date contributions to the field of lipid mediators, focusing on their total synthesis, biosynthesis, structural elucidation, and biopharmaceutical implications. We invite various types of manuscript submissions ranging from original research to review articles.
Dr. Robert Nshimiyimana
Dr. Hong Yong Peh
Guest Editors
Manuscript Submission Information
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Keywords
- total synthesis
- stereochemistry
- resolution of inflammation
- lipid mediators
- structural elucidation
- biosynthesis
- eicosanoids
- docosanoids
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