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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Intelligent and Biomimetic Nanocarriers for Precision Cancer Therapy
edited by Suping Li
submission deadline 31 Dec 2026 | Viewed by 150 | Submission Open
Keywords: intelligent drug delivery; biomimetic nanotechnologies; precision oncology
(This special issue belongs to the Section Medicinal Chemistry)
Application of Nuclear Magnetic Resonance (NMR) Technology in Food Quality Control and Composition Analysis submission deadline 31 Dec 2026 | Viewed by 138 | Submission Open
Keywords: nuclear magnetic resonance (NMR) technology; food quality control; composition analysis; food safety; nutritional analysis
(This special issue belongs to the Section Analytical Chemistry)
Antiviral Medicinal Chemistry Driven by Multidisciplinary Integration submission deadline 31 Dec 2026 | Viewed by 138 | Submission Open
Keywords: multidisciplinary integration; antiviral medicinal chemistry; drug design; target identification; artificial intelligence; structural biology; novel strategies and advanced technologies; drug resistance; broad spectrum antiviral agents
(This special issue belongs to the Section Medicinal Chemistry)
Application of Modern Analytical Techniques in Chinese Medicine
edited by
submission deadline 31 Dec 2026 | Viewed by 135 | Submission Open
Keywords: traditional Chinese medicine; advanced analytical techniques; two-dimensional chromatography; LC-MS metabolomics; bioactive natural products discovery; quality assessment
(This special issue belongs to the Section Analytical Chemistry)
Computational Advances in Molecular Design of Electrolytes
edited by Chao Fang
submission deadline 31 Dec 2026 | Viewed by 135 | Submission Open
Keywords: electrolytes; ion transport; solvation structure; solid–electrolyte interphase; simulation; machine learning
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Bioactive Compounds for the Prevention and Treatment of Diabetes and Metabolic Syndrome
edited by , and Kamila Kasprzak-Drozd
submission deadline 31 Dec 2026 | Viewed by 131 | Submission Open
Keywords: antioxidants; inflammation; polyphenols; CVD; insulin resistance; obesity; oxidative stress
(This special issue belongs to the Section Medicinal Chemistry)
Phytochemicals Beyond Antioxidants: Chemical Profiling, Structural Characterization, and Biological Potential of Plant-Derived Bioactive Compounds
edited by , Katarina Marković and Mirjana Grujović
submission deadline 31 Dec 2026 | Viewed by 123 | Submission Open
Keywords: plant-derived bioactive compounds; plant extracts; essential oils; secondary metabolites; antioxidant activity
(This special issue belongs to the Section Natural Products Chemistry)
Renewable Energy, Fuels and Chemicals from Biomass, 3rd Edition
edited by and
submission deadline 31 Dec 2026 | Viewed by 123 | Submission Open
Keywords: biomass conversion technologies; renewable energy; biofuel synthesis; catalytic biomass transformation; bioethanol; biodiesel; green/sustainable chemistry; biotechnological applications
(This special issue belongs to the Section Applied Chemistry)
Plasmonic Nanoparticles in Cancer Therapy and Detection
edited by
submission deadline 31 Dec 2026 | Viewed by 116 | Submission Open
Keywords: plasmonic nanoparticles; LSPR; cancer detection; biosensing; photothermal therapy; drug delivery; cytotoxicity; nanomedicine; apoptosis; bioimaging
(This special issue belongs to the Section Medicinal Chemistry)
Inorganic Catalysis in Environmental Systems: From Electron Transfer to Organic Matter Transformation
edited by
submission deadline 31 Dec 2026 | Viewed by 110 | Submission Open
Keywords: inorganic catalysis; nanozyme; inorganic enzyme; metal oxides; sulfide minerals; nanomaterials; minerals; environmental catalysis; biogeochemistry; biogeochemical cycling; carbon cycling; nitrogen cycling; phosphorus cycling; greenhouse gases; CO2 transformation; methane oxidation; nitrous oxide; denitrification; nitrification; redox processes; redox cycling; electron transfer; electron hopping; reactive oxygen species (ROS); Fenton reaction; Fenton-like activity; advanced oxidation processes; photocatalysis; photocatalyst; photoinduced electron transfer; solar-driven catalysis; surface catalysis; interfacial reactions; mineral–organic interactions; organic matter transformation; contaminant degradation; emerging contaminants; PFAS; pesticides; microplastics; soil; sediment; aquatic systems; water treatment; environmental remediation; prebiotic chemistry; origin of life; emergence of life; chemical evolution; protein evolution; enzyme evolution; metalloenzymes; iron–sulfur clusters
(This special issue belongs to the Section Green Chemistry)
Photocatalysis: From Degradation of Organic Pollutants in Water to Green Organic Transformations—a Theme Issue in Honor of Professor Wanhong Ma
edited by Yan Yan
submission deadline 31 Dec 2026 | Viewed by 70 | Submission Open
Keywords: photocatalysis; heterogeneous photocatalysis; degradation of organic pollutants; water pollution control; photochemical oxidation; interfacial electron transfer; photocatalytic mechanism; photocatalytic materials; nano‑photocatalysis; oxygen activation; green organic synthesis; sustainable chemistry; environmental photochemistry; TiO2 photocatalysis; advanced oxidation processes
(This special issue belongs to the Section Photochemistry)
Bioaccessibility and Delivery of Food Bioactive Compounds
edited by , Yufan Sun and
submission deadline 31 Dec 2026 | Viewed by 64 | Submission Open
Keywords: bioavailability; functional foods; delivery systems; nanoparticles; biopolymer hydrogels; gastrointestinal fate; controlled release
(This special issue belongs to the Section Food Chemistry)
Advances of Ionic Liquids in Organic, Polymer and Material Chemistry
edited by
submission deadline 31 Dec 2026 | Viewed by 56 | Submission Open
Keywords: reverse micelles; vesicles; nanoparticles; ionic liquids; catalysis; reactions
(This special issue belongs to the Section Molecular Liquids)
Nanozyme-Based Sensing Platforms: Design and Applications
edited by
submission deadline 1 Jan 2027 | 1 articles | Viewed by 442 | Submission Open
Keywords: nanozyme-based sensor; biosensing; environmental monitoring; biomedical diagnosis; pharmaceutical analysis; food safety
(This special issue belongs to the Section Analytical Chemistry)
Advanced Oxidation Processes for Environmental Remediation: Materials and Mechanisms
edited by Lei Qin
submission deadline 1 Jan 2027 | Viewed by 110 | Submission Open
Keywords: advanced oxidation processes; environmental remediation; heterogeneous catalysis; single-atom catalysts; photo-Fenton; electro-persulfate activation; DFT calculations
(This special issue belongs to the Section Green Chemistry)
Small Molecules Derived from and Inspired by Natural Sources: Structure–Activity Relationships and Pharmaceutical Potential submission deadline 10 Jan 2027 | 2 articles | Viewed by 1377 | Submission Open
Keywords: natural products; biologically active compounds; drug discovery; drug development; medicinal chemistry; pharmacology; mechanism of action; structure–activity relationship (SAR); computational drug design; therapeutic applications; natural products; biologically active compounds; drug discovery; drug development; natural origin compounds; medicinal chemistry; bioactive molecules; therapeutic applications; mechanisms of action; natural product-based drugs
(This special issue belongs to the Section Medicinal Chemistry)
Supercritical Fluid Extraction of Natural Products submission deadline 15 Jan 2027 | 3 articles | Viewed by 2834 | Submission Open
Keywords: supercritical fluid extraction (SFE); natural products; green chemistry; carbon dioxide extraction; sustainable extraction; phytochemicals; scale-up; environmentally friendly processes
(This special issue belongs to the Section Natural Products Chemistry)
Metal–Organic Cages: Synthesis and Applications
edited by Simona Nica
submission deadline 15 Jan 2027 | Viewed by 291 | Submission Open
Keywords: synthetic strategies; self-assembly processes; crystal engineering; computational studies; post-synthetic functionalization
(This special issue belongs to the Section Organic Chemistry)
Chemical Recycling of Solid Waste from New Energy Sources
edited by Yanling Gu
submission deadline 15 Jan 2027 | Viewed by 84 | Submission Open
Keywords: recycling technology; metal recovery; waste valorization; lithium-ion batteries; environmental impacts
(This special issue belongs to the Section Green Chemistry)
Novel Food Processing Technologies and Their Effects on Bioactive Components in Foods
edited by and Xiao Wang
submission deadline 16 Jan 2027 | 4 articles | Viewed by 4243 | Submission Open
Keywords: food processing technologies; bioactive constituents; nutrient retention; functional foods; bioavailability; non-thermal processing; sustainable processing; in vitro digestion models; metabolomics
(This special issue belongs to the Section Food Chemistry)
Chromatography for Bio (Analytical) Applications submission deadline 25 Jan 2027 | Viewed by 242 | Submission Open
Keywords: sample preparation; liquid chromatography; gas chromatography; separation techniques; mass spectrometry; forensic and toxicological analysis; environmental and wastewater analysis; food analysis; biological samples; pharmaceuticals; natural products; omics; drug delivery systems; microorganism-related analysis; chiral separation
(This special issue belongs to the Section Analytical Chemistry)
Advanced Materials for Energy Applications: From Fuels to Batteries and Beyond, 2nd Edition
edited by
submission deadline 30 Jan 2027 | 3 articles | Viewed by 2545 | Submission Open
Keywords: hydrogen storage materials; CO2 capture; natural gas sweetening; fossil fuel recovery
(This special issue belongs to the Section Materials Chemistry)
Natural Product Leads Targeting Inflammatory Pathways submission deadline 30 Jan 2027 | 1 articles | Viewed by 1459 | Submission Open
Keywords: natural products; lead compounds; anti-inflammatory; inflammatory pathways; drug discovery; medicinal plants; phytochemistry
(This special issue belongs to the Section Natural Products Chemistry)
Supramolecular Catalytic Systems Build on Macrocycle-Base Host-Guest Interactions
edited by
submission deadline 30 Jan 2027 | 1 articles | Viewed by 1042 | Submission Open
Keywords: supramolecular catalysis; host–guest systems; macrocycles; noncovalent interactions; microenvironments; activity; stimuli-responsiveness; enantioselectivity/selectivity; transition state stabilization; product inhibition; tandem catalysis
(This special issue belongs to the Section Organic Chemistry)
Biological Properties of Terpenoids submission deadline 30 Jan 2027 | Viewed by 478 | Submission Open
Keywords: terpenoids; biological activities; anticancer; anti-infectives; anti-inflammatory; antioxidant
(This special issue belongs to the Section Natural Products Chemistry)
Natural Product Leads for Managing Metabolic Diseases submission deadline 30 Jan 2027 | Viewed by 348 | Submission Open
Keywords: diabetes; metabolic syndrome; metabolic diseases; natural products; mechanisms; drug discovery
(This special issue belongs to the Section Natural Products Chemistry)
Featured Reviews in Bioorganic Chemistry submission deadline 30 Jan 2027 | Viewed by 277 | Submission Open
Keywords: bioorganic chemistry; enzyme inhibitors; biocatalysis; biosynthesis; immunochemical techniques; membrane chemistry; peptides chemistry
(This special issue belongs to the Section Bioorganic Chemistry)
Natural-Based Sorbents for Water Remediation submission deadline 31 Jan 2027 | 4 articles | Viewed by 6382 | Submission Open
Keywords: natural sorbents; removal of organic or inorganic contaminants from water; physical and chemical characterization of the sorbent; kinetic and equilibrium sorptive tests; evaluation of thermodynamic and kinetic parameters; determination of the actual sorption mechanism
(This special issue belongs to the Section Physical Chemistry)
Natural Extracts for Pharmaceutical Applications
edited by
submission deadline 31 Jan 2027 | 4 articles | Viewed by 5876 | Submission Open
Keywords: natural compounds; phytochemicals; bioactive compounds; medicinal plants; phytopharmacology; antioxidant activity; anti-inflammatory; antimicrobial; antidiabetic; wound healing
(This special issue belongs to the Section Medicinal Chemistry)
Analytical Chemistry in Europe: Towards Sustainability and Quality of Life, 3rd Edition submission deadline 31 Jan 2027 | 4 articles | Viewed by 5722 | Submission Open
Keywords: analytical and bioanalytical methods; chemistry; drugs; toxic compounds; biomarkers; sample preparation; life quality; sustainability
(This special issue belongs to the Section Analytical Chemistry)
Inorganic Chemistry in Asia, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 5 articles | Viewed by 5575 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; organometallic chemistry; solid-state chemistry; bioinorganic chemistry; nuclear- and radiochemistry; theoretical calculation
(This special issue belongs to the Section Inorganic Chemistry)
Advances in Plant-Based Materials
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 5386 | Submission Open
Keywords: isolation; investigation; plant compounds; bioactive activity; extraction techniques; chromatographic techniques; electromigrational techniques
(This special issue belongs to the Section Natural Products Chemistry)
Pharmaceuticals in the Environment: Micropollutants and Degradation Dynamics
edited by Agnieszka Nowak and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 5363 | Submission Open
Keywords: pharmaceuticals; microorganisms; toxicity; micropollutants; biodegradation; biotransformation; advanced oxidation processes; analysis; intermediate identification; chromatography
(This special issue belongs to the Section Green Chemistry)
Quantum Chemistry in Modern Science: Chemical Bonding, Spectroscopy, and Beyond
edited by Isuru R. Ariyarathna
submission deadline 31 Jan 2027 | 4 articles | Viewed by 4655 | Submission Open
Keywords: quantum chemistry; ab initio multireference methods; coupled-cluster; density functional theory; spectroscopy; chemical bonding; transition metals; lanthanides; actinides
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Rational Design, Synthesis, and Evaluation of Small-Molecule Anticancer Agents
edited by and Ganga Reddy Velma
submission deadline 31 Jan 2027 | 3 articles | Viewed by 4347 | Submission Open
Keywords: drug design; medicinal chemistry; organic synthesis; total synthesis; multi-drug resistance; biological activity; anti-cancer; heterocyclic compounds; cytotoxicity; structure–activity relationship; molecular modeling
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Compounds in Food: Extraction and Characterization submission deadline 31 Jan 2027 | 4 articles | Viewed by 4224 | Submission Open
Keywords: bioactive compounds; food matrices; extraction techniques; green technologies; analytical characterization; structural elucidation; stability and bioavailability; functional food applications
(This special issue belongs to the Section Food Chemistry)
Carbon-Based Materials for Sustainable Chemistry: 3rd Edition
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 4025 | Submission Open
Keywords: carbon-based materials; carbon nanostructures; adsorption; sustainability
(This special issue belongs to the Section Materials Chemistry)
Applications of Natural Polymers in Biomedicine submission deadline 31 Jan 2027 | 3 articles | Viewed by 3934 | Submission Open
Keywords: polymer biomaterials; biopolymers; proteins; polysaccharides; gels; hydrogels; scaffolds; films
(This special issue belongs to the Section Medicinal Chemistry)
Lignin Valorization in Biorefineries
edited by Carlos Eduardo De Araújo Padilha, Everaldo Silvino Dos Santos and Domingos Fabiano de Santana Souza
submission deadline 31 Jan 2027 | 3 articles | Viewed by 3561 | Submission Open
Keywords: pretreatment; bioactive compounds; antioxidant properties; kraft lignin; extraction; thermochemical processes
(This special issue belongs to the Section Green Chemistry)
Review Papers in Materials Chemistry—2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 3297 | Submission Open
Keywords: materials chemistry; organic and inorganic materials; biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; tailored and unusual properties of materials
(This special issue belongs to the Section Materials Chemistry)
Selectivity and Theoretical Studies of Cycloaddition Reactions
edited by , and Ewa Dresler
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2948 | Submission Open
Keywords: cycloaddition; selectivity; density functional theory (DFT); reaction mechanisms; catalysis; stereocontrol
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Extraction, Chromatography, and Mass Spectrometry Analysis of Food and Plant Biomolecules submission deadline 31 Jan 2027 | 1 articles | Viewed by 2919 | Submission Open
Keywords: liquid chromatography; gas chromatography; sample preparation; extraction; supercritical fluid extraction; solid-phase extraction; liquid–liquid extraction
(This special issue belongs to the Section Analytical Chemistry)
Corrosion Mechanisms and Protection Technologies of Metallic Materials Under Harsh Environments
edited by Baojun Dong, , Dezhi Zeng and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2789 | Submission Open
Keywords: metal coating; non-metal coating; coating design and preparation; coating performance evaluation; corrosion mechanism in harsh environments
(This special issue belongs to the Section Materials Chemistry)
Natural and Sustainable Emulsions: Design, Stabilization, and Functional Applications submission deadline 31 Jan 2027 | 1 articles | Viewed by 2753 | Submission Open
Keywords: natural emulsifiers; pickering emulsions; biopolymer stabilization; microencapsulation; sustainable formulations; bio-based materials
(This special issue belongs to the Section Materials Chemistry)
Porous Organic Materials: Design and Applications, 3rd Edition
edited by and Qi Chen
submission deadline 31 Jan 2027 | 1 articles | Viewed by 2626 | Submission Open
Keywords: topology design; synthesis; structure−function correlation; adsorption and separation; catalysis; energy storage and conversion; mass transportation; biological application
(This special issue belongs to the Section Materials Chemistry)
Ligand-Based Design and Optimization of Antibacterial Agents: From Structure to Activity submission deadline 31 Jan 2027 | 2 articles | Viewed by 2595 | Submission Open
Keywords: ligand-based drug design (LBDD); antibacterial agents; quantitative structure–activity relationship (QSAR); pharmacophore modeling; virtual screening; cheminformatics; molecular optimization
(This special issue belongs to the Section Medicinal Chemistry)
Biopolymer-Based Materials: Preparation, Properties and Applications
edited by
submission deadline 31 Jan 2027 | 4 articles | Viewed by 2539 | Submission Open
Keywords: biopolymer; biopolymer based; material; preparation; processing; characterization; modification; physicochemical; mechanical; application; packaging; biomedical engineering; agriculture; environmental remediation
(This special issue belongs to the Section Green Chemistry)
Development of Active Bio-Packaging Films for Food Industry with Natural Bioactive Compounds
edited by Renata Dobrucka
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2493 | Submission Open
Keywords: active packaging; natural compounds; biomaterials; biocomposites; natural polymers; polysaccharides; packaging materials
(This special issue belongs to the Section Materials Chemistry)
Modern Sample Preparation Approaches for Separation Science, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2373 | Submission Open
Keywords: sample preparation; enrichment techniques; sorption-based methods; virtual sample preparation; microextraction techniques; new analytical strategies; separation techniques
(This special issue belongs to the Section Analytical Chemistry)
Advances in European Materials Chemistry submission deadline 31 Jan 2027 | 2 articles | Viewed by 2308 | Submission Open
Keywords: carbon-based materials; nanomaterials; nuclear materials; luminescent materials; textile materials; biomaterials; interfaces in material systems; hybrid organic–inorganic materials; thin films and coatings; self-assembling systems; nanocomposites; thermal behavior; durability
(This special issue belongs to the Section Materials Chemistry)
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