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Bioactive Compounds for the Prevention and Treatment of Diabetes and Metabolic Syndrome

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 10

Special Issue Editors


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Guest Editor
Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, 20-080 Lublin, Poland
Interests: antioxidants; chromatography; clinical pharmacology; environmental pollutants
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland
Interests: polyphenols; functional food; extraction

Special Issue Information

Dear Colleagues,

In recent years, diabetes and metabolic syndrome (i.e., MetS) have become major global health challenges, as well as being among the most widely discussed topics in the fields of medicine and pharmacy. MetS is recognised as a group of related metabolic abnormalities, including central obesity, impaired glucose tolerance, insulin resistance, dyslipidaemia, hypertension and chronic low-grade inflammation. These conditions markedly increase the risk of type 2 diabetes and cardiovascular disease. Despite substantial progress in our understanding of these disorders, their pathogenesis is complex and multifactorial, involving genetic predisposition, environmental influences, lifestyle factors, oxidative stress and inflammatory pathways.

This Special Issue, entitled 'Bioactive Compounds for the Prevention and Treatment of Diabetes and Metabolic Syndrome', aims to present the latest advances in identifying and biologically evaluating natural and synthetic bioactive compounds that could have beneficial effects on these disorders. We welcome original research articles and reviews that address the molecular mechanisms, pharmacological activity, bioavailability and therapeutic potential of compounds such as polyphenols, alkaloids, terpenoids and peptides. Studies focusing on prevention strategies, modulation of metabolic pathways and innovative approaches to supporting the management of diabetes and MetS are particularly encouraged.

We hope that this Special Issue will contribute to a better understanding of the role of bioactive compounds in improving metabolic health, and will inspire further interdisciplinary research in this important field.

Dr. Przemysław Niziński
Prof. Dr. Anna Oniszczuk
Dr. Kamila Kasprzak-Drozd
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • inflammation
  • polyphenols
  • CVD
  • insulin resistance
  • obesity
  • oxidative stress

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Published Papers

This special issue is now open for submission.
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