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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Food Chemistry and Bioactive Compounds in Relation to Health, 3rd Edition submission deadline 31 Dec 2026 | 2 articles | Viewed by 1280 | Submission Open
Keywords: biologically active compounds; functional food ingredients; metabolic pathways; health benefits; foodborne pathogens; probiotics; chromatographic analysis; enzymes applied in the food industry
(This special issue belongs to the Section Food Chemistry)
Challenges in Food Flavor and Volatile Compounds Analysis, the Second Edition submission deadline 31 Dec 2026 | 1 articles | Viewed by 1245 | Submission Open
Keywords: flavor; aroma compounds; volatiles; gas chromatography; mass spectrometry; sample preparation; hyphenated methods
(This special issue belongs to the Section Flavours and Fragrances)
Light and Electric Field Driven Catalysis for Sustainable Energy and Environment
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1233 | Submission Open
Keywords: photocatalysis; electrocatalysis; photoelectrocatalysis; solar fuels; CO2 reduction; environmental remediation; charge transfer; interface engineering; sustainable chemistry
(This special issue belongs to the Section Applied Chemistry)
Inclusion Complex: Formation, Structure and Properties
edited by , Wagner De Almeida and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1204 | Submission Open
Keywords: inclusion complex; host–guest interaction; computational chemistry; intermolecular interactions; structural characterization; supramolecular interactions
(This special issue belongs to the Section Molecular Structure)
Synthesis, Modification, and Bioactive Evaluation of Peptides and Their Analogs
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 1203 | Submission Open
Keywords: biologically active peptides; bioconjugates with peptides; peptide ligands; biological activity; non-proteinogenic amino acids; peptide mimetics
(This special issue belongs to the Section Chemical Biology)
Recent Advances of Biochar in Wastewater Treatment submission deadline 31 Dec 2026 | 2 articles | Viewed by 1197 | Submission Open
Keywords: biochar; wastewater treatment; adsorption; hybrid treatment; sorbent; catalyst; composite; heavy metals; nutrients; pharmaceuticals; circular economy; life cycle assessment
(This special issue belongs to the Section Applied Chemistry)
Metal Clusters and Metal Complexes: Free Standing Species, Surface Stabilized Species, Species Under Confinement in Micropores or Inert Gas Matrixes
edited by Peter A. Georgiev
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1172 | Submission Open
Keywords: metal clusters; metal complexes; targeted delivery; cancer treatment research; bactericidal; spinal cord recovery; nerve regeneration; progressive neurodegenerative disease diagnosis and treatment
(This special issue belongs to the Section Organometallic Chemistry)
Doping Strategies for Carbon-Based Electrocatalysts
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1168 | Submission Open
Keywords: carbons; p-doping; n-doping; Fermi level engineering; electrocatalysis; electrochemical sensors; energy conversion and storage; environmental remediation
(This special issue belongs to the Section Electrochemistry)
Anticancer Drugs: Design, Synthesis, and Anticancer Activity
edited by Yusuf Tutar
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1154 | Submission Open
Keywords: structure–activity relationships; pharmacological evaluation; prodrugs and drug delivery; targeted cancer therapy; small molecules, peptides and natural products as anticancer agents; computational drug discovery and virtual screening; mechanism of action studies; in vitro and in vivo anticancer assays; cancer cell signaling modulation
(This special issue belongs to the Section Medicinal Chemistry)
The Development of Photosensitizers and Photodynamic Medicine
edited by and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1151 | Submission Open
Keywords: photodynamic therapy; photosensitizer development; photosensitizer pharmaceutics; photosensitizer composite materials; targeted delivery for photosensitizer; photodynamic dosimetry
(This special issue belongs to the Section Medicinal Chemistry)
Nanocarriers for Diagnostics, Imaging and Drug Delivery
edited by Jie Pan and Yonghui Liu
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1109 | Submission Open
Keywords: nanocarriers; diagnostics; imaging; drug delivery; targeted therapy
(This special issue belongs to the Section Nanochemistry)
Food Fraud, Adulteration, and Contamination: Challenges, Detection Strategies, and Prevention
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 1093 | Submission Open
Keywords: food safety; food quality; food adulteration; sample preparation; emerging food contaminants; quality monitoring; mass spectrometry; chromatography; food authentication; trace analysis; analytical methods
(This special issue belongs to the Section Food Chemistry)
Advancements in Enzyme Immobilization Techniques submission deadline 31 Dec 2026 | Viewed by 1043 | Submission Open
Keywords: enzyme immobilization; biocatalysis; enzyme stabilization; reusability/recyclability; activity retention; operational stability; mass transfer limitation
(This special issue belongs to the Section Applied Chemistry)
Extraction and Biological Evaluation of Active Substances in Food submission deadline 31 Dec 2026 | 2 articles | Viewed by 1041 | Submission Open
Keywords: bioactive compounds; food-derived active substances; extraction techniques; green extraction; food chemistry; natural products; phytochemicals; antioxidant activity; biological activity; functional foods; nutraceuticals; metabolomic profiling; bioavailability; in vitro bioassays; food bioactives
(This special issue belongs to the Section Food Chemistry)
Advances in Polymeric Systems Loaded with Natural Bioactive Compounds submission deadline 31 Dec 2026 | 1 articles | Viewed by 1041 | Submission Open
Keywords: polymer-based delivery systems with natural bioactive principles encapsulated; polyphenols/flavonoids; polymer–drug conjugates; drug delivery system; natural bioactive compounds; active targeting; omega 3 fatty acids; carotenoids; vitamins; nanoparticles; nanocapsules; liposomes; hydrogels
(This special issue belongs to the Section Macromolecular Chemistry)
Silymarin and Derivatives: From Biosynthesis to Health Benefits 2.0
edited by
submission deadline 31 Dec 2026 | Viewed by 1027 | Submission Open
Keywords: silymarin: sources and biosynthesis; secondary metabolites and silymarin derivatives; silymarin bioavailability; silymarin and cardiovascular diseases; silymarin and metabolic syndrome; silymarin and cancer; silymarin and inflammation and immune diseases; silymarin and degenerative age-related diseases
(This special issue belongs to the Section Natural Products Chemistry)
Challenges and Advances in Green Analytical Chemistry submission deadline 31 Dec 2026 | 1 articles | Viewed by 994 | Submission Open
Keywords: green analytical chemistry; miniaturized extraction; nanomaterials; chromatography; mass spectrometry; environmental analysis; food analysis; bioanalytical chemistry; sustainability; novel methods
Recent Advances in Circularly Polarized Luminescence Materials
edited by and Biao Zhao
submission deadline 31 Dec 2026 | 1 articles | Viewed by 990 | Submission Open
Keywords: circularly polarized luminescence; chirality; small molecules; polymers; chiral liquid crystals; self-assembled materials; optoelectronics; information security
(This special issue belongs to the Section Materials Chemistry)
Advanced Molecular Detection and Health Risk Evaluation: From Food Hazards to Disease Biomarkers
edited by and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 982 | Submission Open
Keywords: molecular detection; foodborne hazards; emerging contaminants; toxicity mechanisms; nuclear receptors; health risk evaluation; cancer biomarkers
(This special issue belongs to the Section Analytical Chemistry)
Bioactive Molecules in Sustainable Food Packaging: From Natural Sources to Functional Materials
edited by Mia Kurek
submission deadline 31 Dec 2026 | 2 articles | Viewed by 969 | Submission Open
Keywords: functional food packaging materials; controlled release; stability of active compounds; scalability
(This special issue belongs to the Section Materials Chemistry)
Curcumin Derivatives: Synthesis, Structural Diversity and Biological Potential
edited by Raul G. Enriquez and Marco A. Obregón-Mendoza
submission deadline 31 Dec 2026 | 1 articles | Viewed by 954 | Submission Open
Keywords: curcumin; demethoxycurcumin; bisdemethoxycurcumin; antioxidant activities; anti-cancer activities; anti-Alzheimer disease; curcuminoid metal complexes; curcumin-based fluorescent probes
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Approaches for Extraction and Characterization of Bioactive Compounds from Natural Products submission deadline 31 Dec 2026 | 2 articles | Viewed by 932 | Submission Open
Keywords: bioactive compounds; natural products; extraction techniques; green extraction; analytical characterization; process optimization
(This special issue belongs to the Section Natural Products Chemistry)
Optical Functional Materials: Design, Synthesis and Applications
edited by Tamara Potlog and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 921 | Submission Open
Keywords: optical; design; synthesis; application; material; physical; structural; inorganic; organic; hybrid; solid-state laser; thin film; nonlinear; mechanistic; optimization
(This special issue belongs to the Section Materials Chemistry)
Next-Generation Electrochemical Sensors for a Sustainable Future submission deadline 31 Dec 2026 | 1 articles | Viewed by 917 | Submission Open
Keywords: electrochemical sensors; next-generation sensors; sustainable materials; novel materials; sustainable applications
(This special issue belongs to the Section Electrochemistry)
Advanced Pharmaceutical Analytical Technology—2nd Edition submission deadline 31 Dec 2026 | 1 articles | Viewed by 903 | Submission Open
Keywords: pharmaceutical; quality by design; design of experiments; analytical method; validation; development and optimization; quality control samples
(This special issue belongs to the Section Analytical Chemistry)
Chemical Compositions and Bioactivities of Foods, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 893 | Submission Open
Keywords: foods; phytochemicals; biophytochemicals; food bioactives; chemical compositions; functional foods; dietary supplements; medical foods; biological pathway; molecular mechanisms
(This special issue belongs to the Section Food Chemistry)
Applied Analytical Chemistry: Third Edition submission deadline 31 Dec 2026 | 1 articles | Viewed by 875 | Submission Open
Keywords: food production; forensic practice and archaeology; environmental monitoring; clinical practice; quality control in industry; analysis of plant material
(This special issue belongs to the Section Analytical Chemistry)
Exclusive Contributions by the Editorial Board Members (EBMs) of the Organic Chemistry Section of Molecules, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 859 | Submission Open
Keywords: organic compounds; organic synthesis; organic reaction; click chemistry; organocatalysis
(This special issue belongs to the Section Organic Chemistry)
Bee Products: Physicochemical Properties, Bioactivities, and Health Benefits submission deadline 31 Dec 2026 | 1 articles | Viewed by 800 | Submission Open
Keywords: honey bee products; chemical characterization; biological and pharmacological activities; health benefits; side effects of honey bee products
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Small Bioactive Molecules: From Molecular Pathways to Health Benefits submission deadline 31 Dec 2026 | 1 articles | Viewed by 788 | Submission Open
Keywords: small bioactive molecules; nutraceuticals; functional foods; disease prevention; diet–health interactions; signal transduction pathways
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Plant-Sourced Natural Compounds as Anticancer Agents, 2nd Edition submission deadline 31 Dec 2026 | Viewed by 779 | Submission Open
Keywords: medicinal plants; natural compounds; phytochemicals; antioxidant activity; anticancer activity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation
(This special issue belongs to the Section Natural Products Chemistry)
MOF-Based Catalysts for CO2 Capture and Conversion
edited by Ning Liu and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 762 | Submission Open
Keywords: metal–organic frameworks (MOFs); CO2 capture and conversion; heterogeneous catalysis; sustainable catalysis; porous materials; green chemistry; structure–activity relationship; carbon utilization
(This special issue belongs to the Section Materials Chemistry)
Design, Synthesis, and Biological Evaluation of Novel Metal Complexes submission deadline 31 Dec 2026 | 1 articles | Viewed by 760 | Submission Open
Keywords: coordination compound; 3d metal complexes; biological activity; anticancer activity; selectivity; toxicity; antioxidant activity; antibacterial activity; mechanism of action
(This special issue belongs to the Section Medicinal Chemistry)
Molecular Insights into Essential Oils and Plant Extracts: Chemistry, Bioactivity, and Functional Relevance submission deadline 31 Dec 2026 | 1 articles | Viewed by 737 | Submission Open
Keywords: essential oils; plants; bioactivity; functional foods
(This special issue belongs to the Section Natural Products Chemistry)
Tautomerism and Proton Transfer—Fundamental Aspects and Applicability
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 724 | Submission Open
Keywords: tautomerism; proton transfer; hydrogen bonding; molecular switches; molecular sensors; dye chemistry; organic synthesis; solvent effect; photo-, halo-, and thermochromism; molecular spectroscopy; computational chemistry; photochemistry
(This special issue belongs to the Section Physical Chemistry)
Functional Carbon Materials from Biomass for Environmental Applications
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 707 | Submission Open
Keywords: biomass-derived carbon; functional carbon materials; activated carbon; biochar; porous carbon; surface functionalization; structure-property relationships; biomass valorization; circular economy; environmental remediation; water treatment; adsorption and catalysis; electrocatalysis; green synthesis; sustainable materials
(This special issue belongs to the Section Materials Chemistry)
New Synthetic Drugs of Abuse submission deadline 31 Dec 2026 | 1 articles | Viewed by 691 | Submission Open
Keywords: new psychoactive substances (NPS); structure–activity relationships; pharmacokinetics and pharmacodynamics; toxicological mechanisms; advanced analytical methodologies; biomarkers of exposure
(This special issue belongs to the Section Medicinal Chemistry)
Light-Driven Organic Chemistry: Synthesis, Mechanisms, and Photochemical Applications
edited by and Fernando Heering Bartoloni
submission deadline 31 Dec 2026 | 1 articles | Viewed by 690 | Submission Open
Keywords: organic photochemistry; light-driven synthesis; photocatalysis; excited-state chemistry; photophysical properties; mechanistic investigations; photoresponsive molecules
(This special issue belongs to the Section Photochemistry)
Cyclodextrin Chemistry and Toxicology, 4th Edition
edited by and Gianluca D’Abrosca
submission deadline 31 Dec 2026 | 1 articles | Viewed by 687 | Submission Open
Keywords: inclusion complexes; cyclodextrin derivates; biological activities of cyclodextrin; pharmacology and pharmacokinetics of cyclodextrin; industrial applications of cyclodextrins; nano-materials and nano-structured coatings containing cyclodextrins; environmental remediation of cyclodextrins; toxicity of cyclodextrin inclusion complexes
(This special issue belongs to the Section Applied Chemistry)
Synthesis, Doping, and Thermoelectric Properties of Chalcogenide Materials
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 686 | Submission Open
Keywords: chalcogenide thermoelectrics; chemical synthesis and modification; doping and defect chemistry; non-stoichiometry and vacancies; structure-property relationships; electron-phonon interactions; low lattice thermal conductivity
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Asymmetric Synthesis: From Reagents to Reactions
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 672 | Submission Open
Keywords: asymmetric synthesis; enantioselective catalysis; chiral reagents; asymmetric catalysis; stereoselective reactions; catalyst design; sustainable synthesis; organic synthesis
(This special issue belongs to the Section Organic Chemistry)
Medicinal Chemistry and Virology Together in the Service of Human Health: In Honor of Prof. Dr. Erik De Clercq on the Occasion of His 85th Birthday
edited by Libor Grubhoffer, and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 636 | Submission Open
Keywords: antiviral agents; medicinal chemistry; virology; nucleoside/nucleotide analogs; HIV therapeutics; drug development
(This special issue belongs to the Section Medicinal Chemistry)
Environmentally Friendly Biobased Flame Retardants for Polymeric Materials
edited by Yao Yuan and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 611 | Submission Open
Keywords: biobased flame retardants; polymeric materials; sustainable materials; fire safety; green chemistry; biobased coatings; smoke suppression; char formation; multifunctional materials; polymer composites
(This special issue belongs to the Section Materials Chemistry)
Beyond Convention: Novel Sources, Strategies, and Technologies for Researching Fungal Bioactives submission deadline 31 Dec 2026 | Viewed by 600 | Submission Open
Keywords: fungal bioactives; genome mining; metagenomics; synthetic biology; AI-driven discovery; structure elucidation; extremophilic fungi; drug discovery pipelines
Analytical Techniques for Environmental Contamination
edited by Shiming Song
submission deadline 31 Dec 2026 | 1 articles | Viewed by 597 | Submission Open
Keywords: environmental analytical chemistry; environmental monitoring; pollution control; pollution monitoring; green methodologies
(This special issue belongs to the Section Analytical Chemistry)
Challenges in Green Analytical Chemistry submission deadline 31 Dec 2026 | Viewed by 593 | Submission Open
Keywords: green analytical chemistry; sustainable analytical methods; eco-friendly sample preparation; miniaturized techniques; solvent reduction; greenness assessment tools; waste minimization; renewable analytical materials; energy-efficient analysis; green metrics in chemistry
Computational Chemistry of Non-Covalent and Coordination Interactions submission deadline 31 Dec 2026 | 1 articles | Viewed by 574 | Submission Open
Keywords: noncovalent interactions; coordination compounds; hydrogen bonds; metal complexes; stacking interactions; π-interactions; computational chemistry; density functional theory
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Chemistry of Amino Acids, Peptides, and Proteins
edited by and Nicholas Truex
submission deadline 31 Dec 2026 | Viewed by 564 | Submission Open
Keywords: amino acids; peptides; proteins; synthesis; derivatives; characterization; structural studies; biophysical properties; natural products
(This special issue belongs to the Section Macromolecular Chemistry)
Examples and Challenges of Generative AI Use in Inorganic Chemistry Research
edited by Takashiro Akitsu
submission deadline 31 Dec 2026 | 1 articles | Viewed by 553 | Submission Open
Keywords: generative AI in inorganic chemistry; machine learning for inorganic materials; inorganic reaction prediction; AI‑driven coordination chemistry; computational inorganic chemistry; inorganic crystal structure prediction; inorganic synthesis optimization; AI for energy‑related inorganic materials; inorganic photocatalysts; AI‑based electronic structure analysis
(This special issue belongs to the Section Inorganic Chemistry)
Chemical Design of Nanocomposite Materials for Enhanced Electrochemical Performance
edited by and Xingxing Jiao
submission deadline 31 Dec 2026 | Viewed by 546 | Submission Open
Keywords: nanocomposite materials; electrochemical properties; lithium batteries; solid-state electrolytes; interfacial electrochemistry; ionic conductivity; electrode design; theoretical calculations
(This special issue belongs to the Section Electrochemistry)
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