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Challenges and Advances in Green Analytical Chemistry

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 December 2026 | Viewed by 455

Special Issue Editors


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Guest Editor
Unidad Departamental de Química Analítica, Departamento de Química, Facultad de Ciencias, Sección de Química, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
Interests: green analytical and bioanalytical chemistry; separation science; microextraction techniques; sustainable materials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Unidad Departamental de Química Analítica, Departamento de Química, Facultad de Ciencias, Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez, s/n°., 38206 San Cristóbal de La Laguna, Tenerife, Spain
Interests: miniaturized extraction techniques; chromatography; mass spectrometry; food analysis; endocrine disruptors; green chemistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Departamento de Química, Área de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, s/n, 38206 San Cristóbal de La Laguna, Spain
Interests: green analytical chemistry; food and environmental analysis; chromatography; mass spectrometry; supercritical fluids; biological samples; estrogenic compounds; bioactive substances
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Departamento de Química, Área de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, s/n, 38206 San Cristóbal de La Laguna, Spain
2. Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, 38206 San Cristóbal de La Laguna, Spain
Interests: separation techniques; chromatography; green analytical chemistry; extraction; mass spectrometry; environmental samples; agri-food samples; archaeometry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

  1. Introduction: Green analytical chemistry has gained increasing importance as a vital field for developing sustainable and environmentally friendly analytical methods. This approach not only helps reduce the consumption of hazardous chemicals and waste generation but also leads to improved safety and efficiency of analytical processes. Given current environmental challenges and the growing need for sustainable development, research in green analytical chemistry plays a key role in achieving sustainable development goals.
  2. Aim of the Special Issue: This Special Issue aims to compile the latest advancements, innovations, and existing challenges in the field of green analytical chemistry, particularly in the development of new methods, novel materials, and their applications in various fields. This Special Issue intends to serve as a comprehensive reference for researchers, students, and professionals active in this area, and to facilitate the exchange of knowledge and innovative ideas. The topics covered in this Special Issue are fully aligned with the scope of Molecules journal, as they focus on the molecular and chemical aspects of green analytical methods. Our goal is to collect at least 10 high-quality articles, which may also be published as a book.
  3. Suggested themes and article types for submissions: In this Special Issue, original research articles and review articles are welcome. Research areas may include (but are not limited to) the following:
    • Miniaturized and green extraction techniques;
    • Novel materials (e.g., nanomaterials) in green analytical chemistry;
    • Green chromatography and mass spectrometry;
    • Applications of green analytical chemistry in food and environmental analysis;
    • Novel methods in green bioanalytical chemistry;
    • Development of analytical methods with lower energy consumption and higher efficiency;
    • Modeling and optimization of green analytical processes.

Dr. Hakim Faraji
Prof. Dr. Miguel Ángel Rodríguez-Delgado
Dr. Bárbara Socas-Rodríguez
Dr. Antonio V. Herrera-Herrera
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • green analytical chemistry
  • miniaturized extraction
  • nanomaterials
  • chromatography
  • mass spectrometry
  • environmental analysis
  • food analysis
  • bioanalytical chemistry
  • sustainability
  • novel methods

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Published Papers (1 paper)

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Review

27 pages, 1861 KB  
Review
Twenty Years of Dispersive Liquid–Liquid Microextraction: An Umbrella Review of Methodological Quality, Thematic Evolution, and Roadmap for Evidence Integration in Analytical Chemistry
by Hakim Faraji, Adrián Conde Díaz, Álvaro Santana Mayor, Bárbara Socas-Rodríguez and Antonio V. Herrera Herrera
Molecules 2026, 31(11), 1918; https://doi.org/10.3390/molecules31111918 - 2 Jun 2026
Abstract
Over the past two decades, dispersive liquid–liquid microextraction (DLLME) has evolved from an emerging concept into a widely adopted approach within sustainable sample preparation. In parallel, a substantial body of review literature has accumulated, highlighting diverse applications and methodological developments. This umbrella review [...] Read more.
Over the past two decades, dispersive liquid–liquid microextraction (DLLME) has evolved from an emerging concept into a widely adopted approach within sustainable sample preparation. In parallel, a substantial body of review literature has accumulated, highlighting diverse applications and methodological developments. This umbrella review provides a structured synthesis of 59 review and systematic review articles published between 2006 and 2025, with the aim of examining how the review literature itself has shaped current understanding of DLLME. Methodological quality was appraised using the AMSTAR 2 framework, revealing considerable variability in review design and reporting practices. Key elements such as the transparent reporting of pre-defined review methods, fully reproducible search strategies, and structured assessments of bias were not routinely reported, and the majority of reviews were classified as critically low according to AMSTAR 2 criteria. To contextualize these findings, evidence redundancy was examined through structured overlap analysis, yielding a very low Corrected Covered Area (CCA = 0.0188), which indicates that existing reviews largely address complementary rather than repetitive aspects of DLLME. Thematic synthesis identified three dominant domains: methodological and mechanistic developments, green and sustainable extraction strategies, and application-driven advances in environmental and pharmaceutical analysis. Together, these findings provide a structured basis for improving future review design, evaluation, and editorial assessment in analytical chemistry, supporting more transparent, reproducible, and methodologically aligned evidence synthesis. Full article
(This article belongs to the Special Issue Challenges and Advances in Green Analytical Chemistry)
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