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Curcumin Derivatives: Synthesis, Structural Diversity and Biological Potential

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 32

Special Issue Editors


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Guest Editor
Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Mexico City 04510, Mexico
Interests: natural products; NMR spectroscopy; organic chemical structure; curcumin
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor Assistant
Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Mexico City 04510, Mexico
Interests: natural products; fluorescence probes; NMR spectroscopy; organic synthesis; antioxidant products; curcumin; curcuminoids

Special Issue Information

Dear Colleagues,

Molecules is excited to announce its 30th anniversary and invite you to submit your research and findings on curcumin and curcuminoids for our Special Issue titled "Curcumin Derivatives: Synthesis, Structural Diversity and Biological Potential." The scope of this Special Issue is broad, and we welcome articles on various topics, including the synthesis of novel curcuminoids, molecular characterization and spectroscopic analysis of curcuminoids, and curcuminoid metal complexes, as well as studies on the fluorescence and biological activities of curcuminoids. Additionally, theoretical studies and comprehensive reviews will also be considered. We look forward to your valuable contributions to this exciting Special Issue, which aims to deepen our understanding of curcumin and curcuminoids.

Curcumin is the main secondary metabolite extracted from curcuma rhizomes, and in recent years research on this molecule is an exceptional example that occupies almost all topics in the scientific arena, resulting in an exponential growth of publications day by day. The wide worldwide scientific interest in curcumin and curcuminoids is due to the well-documented beneficial medicinal properties, such as antioxidants, anti-cancer, anti-viral, and anti-Alzheimer's disease, among others. This Special Issue addresses, among other topics, the following:

  • Isolation, purification, and structural characterization of curcumin, curcuminoids, and derivatives.
  • Biological activities (antioxidant, cytotoxic, anti-cancer, anti-Alzheimer's, anti-viral, antibacterial, etc.) of curcuminoid compounds of natural or synthetic origin.
  • Cellular metabolism of curcumin, curcuminoids, or derivatives.
  • Green chemistry for synthesis of curcumin of curcuminoids.
  • Food preparations based on turmeric.
  • Development of technologies for the purification of curcuminoids of natural origin.
  • Theoretical studies (docking, DFT, QSAR, etc.) on physicochemical and pharmacological properties of curcumin, curcuminoids, and derivatives.
  • Development of analytical techniques that help the unequivocal elucidation of the main active metabolites of the turmeric rhizome.

Considering the above, our colleagues are invited to present their original research or review work touching on the topics mentioned above in this interesting Special Issue.

Prof. Dr. Raul G. Enriquez
Guest Editor

Dr. Marco A. Obregón-Mendoza
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • curcumin
  • demethoxycurcumin
  • bisdemethoxycurcumin
  • antioxidant activities
  • anti-cancer activities
  • anti-Alzheimer disease
  • curcuminoid metal complexes
  • curcumin-based fluorescent probes

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Published Papers

This special issue is now open for submission.
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