The Development of Photosensitizers and Photodynamic Medicine
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 526
Special Issue Editors
Interests: oncotherapeutics; cancer biology; photosensitizer development; photodynamic oncotherapy; anti-microbial photodynamic therapy; integrated bioinformatic analysis; oncotarget identification
Interests: photodynamic therapy; photosensitizer; phthalocyanine; oncotherapy; antimicrobial therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Photodynamic therapy (PDT), as an agent-device integrating modality, has been broadly applied for selective lesion ablation, especially local proliferative or infectious diseases. Photosensitizer and light present two necessary PDT elements. Rational control of these components is the key to achieving high spatial precision and minimal invasiveness, thereby ensuring the efficacy and safety of PDT in medical applications. Despite the significant preponderances, photodynamic medicine can still be greatly progressed. The approach to further enhance PDT efficacy can predominantly lie in developing more-improved photosensitizers. Higher quantum yield, deeper tissue penetration, faster elimination, better aqueous solubility and dispersity, and active lesion targeting can be continuously pursued. Meanwhile, the innovation of light delivery systems, exemplifying wearable or implantable photonic devices, can enable precise spatiotemporal control and real-time monitoring during treatment. Dosimetric optimization of both photosensitizer and photon delivery also presents another pivotal approach to improve PDT performance.
Based on the aim in progressing photodynamic medicine, this Special Issue welcomes cutting-edge research, comprehensive reviews, and insightful perspectives into the photodynamic field, including, but not limited to, the topic of development of novel photosensitizers, photosensitizer pharmaceutics, photosensitizer composite materials, targeted delivery for photosensitizer, photodynamic dosimetry, and innovative optical devices.
I am looking forward to receiving your brilliant manuscripts.
Dr. Peng Huang
Dr. Peng Xu
Guest Editors
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Keywords
- photodynamic therapy
- photosensitizer development
- photosensitizer pharmaceutics
- photosensitizer composite materials
- targeted delivery for photosensitizer
- photodynamic dosimetry
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