Applied Innovative Insights in Selective Organic Hetero-Synthesis
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 305
Special Issue Editors
Interests: organic chemistry synthesis; heterocyclic chemistry; medicinal and pharmaceutical chemistry; nuclear magnetic resonance; natural product chemistry; organometallics; dendritic chemistry; stereochemistry
Special Issues, Collections and Topics in MDPI journals
Interests: heterocycles; medicinal chemistry; anticancer; antituberculosis; microwave; ultrasounds; organic synthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The recent positive impact of our Special Issue “Advances in the Synthesis of Heterocyclic Compounds and their Applications” prompted us to continue in a somewhat more challenging way, addressing the title formulation to those interested in providing the scientific community with one or more contributions to it.
We expect to gather them in the form of research articles and (updated, critical) reviews that move our standard “yesterday approaches”, namely, hetero-ring synthesis and substituent modification (including their combination), through a perspective/visionary update of their meaning in the milieu of the perpetually valid notion of selectivity. Indeed, despite its explicit prefixes chemo-, regio-, diastereo- and enantio-, it still governs, equally, covalent and non-covalent syntheses. For the research articles, experimental research manuscripts should comprise consistent Materials and Methods and Supplementary Materials (additional file) subsections. The correspondence between the contents of the latter two concerning analytical and spectral data must be complete.
Besides the below proposed eight sub-topics, additional innovative approaches and concepts are also welcome:
- Selective multicomponent, domino and cascade reactions;
- Selectivity in smart hetero-molecule elaboration;
- (Chemo)selectivity in supramolecular hetero-syntheses;
- Organo-catalytic (hetero)systems inducing stereoselectivity;
- Current selectivity insights in total synthesis;
- Selective functional (trans)formations of (bio)organic heterosystems;
- DFT calculations predicting/explaining selectivity in classic/novel organic hetero-syntheses;
- Unconventional methods, organic (nano)materials and techniques ensuring highly selective processes.
We hope to be able to provide an overview of the latest groundbreaking advancements in organic hetero-synthesis consisting of (conceptual) strategies, methodologies, reaction mechanisms, reagents, catalysts, chemical, instrumental auxiliaries, etc. The alluring chemical diversity of heterocyclic compounds, which continuously inspires forward-thinking applications to human life and the environment, we see as a summa summarum of contemporary efforts in accessing them.
Prof. Dr. Mircea Darabantu
Prof. Dr. Ionel Mangalagiu
Guest Editors
Manuscript Submission Information
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Keywords
- hetarenes
- hetero-alycycles
- regioisomerism
- diastereomerism
- enantiomerism
- biomimetics and new chemical entities (NCEs)
- “intelligent” molecules
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