Advances in the Synthesis of Heterocyclic Compounds and Their Applications

Dear Colleagues,

In hopes of attracting your attention, the new topic, “Advances in the Synthesis of Heterocyclic Compounds and Their Applications”, aims to expand our scientific knowledge about the current world by exploring the frontiers between at least two of their lively interfaces: human life and the environment.

In this view, our previous traditional strategies, “heteroring synthesis” and “substituent modification” (including their combination), require an update of their meaning by two actual conceptual approaches, namely “covalent” vs. “non-covalent” with reference to all types of heteromolecules, from the smallest to (supramolecular) 2(3)D nano-architectures (dendrimers, MOFs, COFs, etc.) without neglecting the still “exotic” molecular machines.

Subject to all evolutionary facets of heterocyclic chemistry, the perpetual developments reimagined within the current organic heterosynthesis (strategies, methodologies, reaction mechanisms, reagents, catalysts, chemical and instrumental auxiliaries) nevertheless obey two crucial common denominators, “selectivity” vs. “specificity” (these terms being, equally, preceded by typical prefixes, either chemo-, regio-, or stereo-), as mandatory criteriums.

This Special Issue of “Molecules” is intended to gather research articles, communications, and review papers capable of providing an overview of the latest progresses in synthetic methodologies and chemical technologies targeting heteromolecules, mainly those related to their near future defined as “atomic precision” in chemical reactivity. The sustainability of these efforts, involving intrinsic chemical diversity, is expected to highlight innovative applications of heterocyclic compounds to human life and the environment.

Prof. Dr. Mircea Darabantu
Prof. Dr. Ionel Mangalagiu
Guest Editors

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