Special Issue "Advanced Nanomaterials for Potential Use in Healthcare "

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".

Deadline for manuscript submissions: 31 August 2020.

Special Issue Editor

Dr. Anthony J. Di Pasqua
Website
Guest Editor
Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Science, Binghamton University
Interests: Chemo- and radio-therapeutics; nanomaterials and formulation

Special Issue Information

Dear colleagues,

As a scientific community, we strive to create and improve therapies to treat disease. If we can enhance the efficacy of a therapeutically-active compound by incorporating it into a biocompatible material and, at the same time, limit its toxicity, this is considered a success. However, the real success is getting such materials translated into the clinic. The ability of materials to target disease and control-release their cargo give healthcare providers the ability to improve compliance and health outcomes.

Nanomaterials have been an exciting type of material to explore, but to ensure that our work can move into the clinic, we need to ensure biocompatibility and the improved performance of therapies. Thus, I invite you my colleagues to submit an article for review and potential publication in this Special Issue of Materials entitled “Advanced Nanomaterials for Potential Use in Healthcare”. If your work is in the preparation and characterization of such materials and/or their use in cell or animal models, we would greatly appreciate this opportunity to spotlight your efforts in this area. Thank you.

Dr. Anthony J. Di Pasqua

Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanomaterials
  • Drug delivery systems
  • Biocompatibility
  • Healthcare.

Published Papers (2 papers)

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Research

Open AccessFeature PaperArticle
Biphenyl Wrinkled Mesoporous Silica Nanoparticles for pH-Responsive Doxorubicin Drug Delivery
Materials 2020, 13(8), 1998; https://doi.org/10.3390/ma13081998 - 24 Apr 2020
Abstract
Biphenyl wrinkled mesoporous silica nanoparticles with controlled particle size and high surface area were evaluated for the storage and delivery of doxorubicin. The average particle size and surface area were ~70 nm and ~1100 m2/g. The doxorubicin loading efficiency was 38.2 [...] Read more.
Biphenyl wrinkled mesoporous silica nanoparticles with controlled particle size and high surface area were evaluated for the storage and delivery of doxorubicin. The average particle size and surface area were ~70 nm and ~1100 m2/g. The doxorubicin loading efficiency was 38.2 ± 1.5 (w/w)% and the release was pH dependent. The breast cancer cell line, MCF-7 (Michigan Cancer Foundation-7) was used for the in vitro drug release study. The cytotoxicity of doxorubicin-loaded nanoparticles was significantly higher than free doxorubicin. Fluorescence images showed biphenyl wrinkled mesoporous silica (BPWS) uptake by the MCF-7 cells. The biphenyl bridged wrinkled silica nanoparticles appear promising for hydrophobic drug loading and delivery. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Potential Use in Healthcare )
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Open AccessCommunication
Formula-Driven, Size-Tunable Synthesis of PMMA Nanoparticles by Varying Surfactant Concentration
Materials 2020, 13(8), 1834; https://doi.org/10.3390/ma13081834 - 13 Apr 2020
Abstract
In this communication, we present a streamlined, reproducible synthetic method for the production of size-tunable poly(methyl methacrylate) (PMMA) nanoparticles (PMMANPs) and amine-functionalized block-copolymer PMMANPs (H2N-PMMANPs) by varying subcritical concentrations (i.e., below the concentration required to form micelles at 1 atm and [...] Read more.
In this communication, we present a streamlined, reproducible synthetic method for the production of size-tunable poly(methyl methacrylate) (PMMA) nanoparticles (PMMANPs) and amine-functionalized block-copolymer PMMANPs (H2N-PMMANPs) by varying subcritical concentrations (i.e., below the concentration required to form micelles at 1 atm and 20 °C) of sodium dodecyl sulfate (SDS). We plotted the Z-average size data against SDS concentration, which revealed a second-order exponential decay function, expressed as A 1 e x t 1 + A 2 e x t 2 + y 0 . The surfactant concentration (wt./wt.%) has been selected as independent variable x. This function is valid at least for the size range of 20 nm to 97 nm (PMMANPs) and 20 nm to 133 nm (H2N-PMMANPs). Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Potential Use in Healthcare )
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