Progress in Hemorrhage Control and Blood Transfusion in Trauma

Dear Colleagues, 

Hemorrhage remains the leading cause of preventable death after trauma, particularly in prehospital and operational settings. Advances in damage control resuscitation, blood product therapy, and hemostatic interventions have significantly improved outcomes. Growing understanding of trauma-induced coagulopathy has driven a shift from crystalloid-based resuscitation toward blood-based and precision approaches.

Emerging technologies—including viscoelastic hemostatic assays, point-of-care diagnostics, and artificial intelligence (AI)—are transforming how bleeding and transfusion needs are assessed and managed. Despite these advances, important gaps remain in optimizing transfusion strategies, product selection, and implementation in austere environments.

We are pleased to invite you to contribute to this Special Issue, highlighting recent advances and future directions in trauma hemorrhage control and blood transfusion.

This Special Issue aims to provide an interdisciplinary perspective on innovations in hemorrhage control and transfusion strategies in trauma care. Topics include conventional and emerging approaches such as whole blood resuscitation, dried blood products, targeted coagulation therapies, novel hemostatic materials, and AI-guided decision-making. The Special Issue aligns with the journal’s scope by integrating clinical, translational, and technological research to improve outcomes in both civilian and military settings.

We invite researchers and clinicians to contribute original research articles, reviews, and perspectives to this Special Issue and look forward to receiving your contributions.

Dr. Henry Peng
Dr. Jeffrey Anderson
Guest Editors

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