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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition

edited by

Tomasz Rechciński

submission deadline 25 Feb 2027 | 2 articles | Viewed by 2044 | Submission Open

Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure

(This special issue belongs to the Section Cardiology)

Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition

edited by

Evangelos Oikonomou

and Konstantinos Mourouzis

submission deadline 25 Feb 2027 | 2 articles | Viewed by 1927 | Submission Open

Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease

(This special issue belongs to the Section Cardiology)

Optimizing Radiotherapy in Clinical Practice: Innovation and Outcomes

edited by

Sarah Han-Oh

Senthamizhchelvan Srinivasan

and Joseph Moore

submission deadline 25 Feb 2027 | 2 articles | Viewed by 1441 | Submission Open

Keywords: AI-assisted automated contouring and planning; AI-assisted quality assurance; AI-assisted safety and quality improvement; radiotherapy automation; radiomics; radiotherapy error detection; personalized radiopharmaceutical therapy; theranostics; online adaptive radiotherapy; real-time treatment adaptation; image-guided radiotherapy (IGRT); AI-assisted online adaptation; personalized radiotherapy; cone-beam CT adaptation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Updates and Current Challenges in Obstetrical Anesthesia

edited by Michael Froelich

submission deadline 25 Feb 2027 | 1 articles | Viewed by 1293 | Submission Open

Keywords: obstetrical anesthesia; clinical innovation; practice guidelines; neuraxial techniques; enhanced recovery; risk stratification; maternal safety; multimodal analgesia; health systems innovation; global and low-resource care

(This special issue belongs to the Section Obstetrics & Gynecology)

Emerging Trends and Therapeutic Innovations in Corneal and Ocular Surface Disorders

edited by

Zala Lužnik Marzidovšek

and Špela Štunf Pukl

submission deadline 25 Feb 2027 | 2 articles | Viewed by 1224 | Submission Open

Keywords: corneal diseases; ocular surface disorders; regenerative medicine; stem cell therapy; gene therapy; nanomedicine and targeted drug delivery

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease—2nd Edition

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 25 Feb 2027 | 2 articles | Viewed by 1111 | Submission Open

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

Pediatric Sleep Health: From Pathophysiology to Quality of Life

edited by

Melanie Koelbel

and

Fenella Jane Kirkham

submission deadline 25 Feb 2027 | 1 articles | Viewed by 856 | Submission Open

Keywords: pediatric sleep; sleep disorders; child development; cognition; quality of life; neurodevelopment; pathophysiology; sleep health interventions; academic; sleep-disordered breathing; MRI; neuroscience

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases

edited by

Nikolaos Pararas

submission deadline 25 Feb 2027 | 1 articles | Viewed by 566 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 25 Feb 2027 | Viewed by 388 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Surgical Innovations in Pediatric Orthopedics

edited by

Hoon Park

submission deadline 25 Feb 2027 | Viewed by 374 | Submission Open

Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing

(This special issue belongs to the Section Orthopedics)

Advances in Minimally Invasive and Endoscopic Neurosurgery

edited by Shunsuke Shibao

submission deadline 25 Feb 2027 | Viewed by 354 | Submission Open

Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Exercise, Rehabilitation, and Women’s Health: Clinical Perspectives in Sports Medicine

edited by

Do-yeon Kim

and

Dan Newmire

submission deadline 25 Feb 2027 | Viewed by 281 | Submission Open

Keywords: women’s health; exercise intervention; rehabilitation; exercise physiology; musculoskeletal health; healthy aging; resistance training; nutrition

(This special issue belongs to the Section Clinical Rehabilitation)

Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 25 Feb 2027 | Viewed by 273 | Submission Open

Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities

(This special issue belongs to the Section Epidemiology & Public Health)

Pelvic Floor Disorders: Emerging Perspectives on Therapeutic Approaches

edited by

María Luísa Sánchez-Ferrer

submission deadline 25 Feb 2027 | Viewed by 147 | Submission Open

Keywords: pelvic floor surgery; laparoscopic approach; quality of life; pelvic organ prolapse surgery; urinary and fecal incontinence; pelvic floor disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Colorectal Surgery: New Clinical Advances, Challenges and Future Directions

edited by

Lior Segev

submission deadline 25 Feb 2027 | Viewed by 77 | Submission Open

Keywords: colon surgery; colorectal surgery; colorectal cancer; IBD surgery; proctology; diverticular disease; diverticulitis; surgical outcomes

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Immunohematology: From Pathophysiology to Tailored Treatments

edited by

Giorgio Costagliola

submission deadline 28 Feb 2027 | 1 articles | Viewed by 4366 | Submission Open

Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination

(This special issue belongs to the Section Immunology & Rheumatology)

Tumor Microenvironment—Current Status and Therapeutic Targets

edited by

Rashi Kalra

submission deadline 28 Feb 2027 | 2 articles | Viewed by 3883 | Submission Open

Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies

(This special issue belongs to the Section Oncology)

Clinical Rehabilitation Strategies and Exercise for Stroke Recovery

edited by

Dimitrios I. Tsiptsios

submission deadline 28 Feb 2027 | 3 articles | Viewed by 2312 | Submission Open

Keywords: stroke; stroke rehabilitation; exercise; biomarkers; rehabilitation outcomes

(This special issue belongs to the Section Clinical Rehabilitation)

Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)

edited by Aikaterini Detoraki

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1962 | Submission Open

Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management

(This special issue belongs to the Section Immunology & Rheumatology)

Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management

edited by

Janan Abbas

and

Deborah Alperovitch

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1917 | Submission Open

Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics

(This special issue belongs to the Section Orthopedics)

Clinical and Epidemiological Aspects of Frailty in Acute Kidney Injury: A Spotlight on Risk Factors, Prevention and Management

edited by

Alberto Parise

and

Marco Allinovi

submission deadline 28 Feb 2027 | 1 articles | Viewed by 251 | Submission Open

Keywords: sarcopenia; AKI; frailty; amyloidosis; nutrition; epidemiology

(This special issue belongs to the Section Nephrology & Urology)

Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation

edited by Katarzyna A. Majewska and Piotr Fichna

submission deadline 2 Mar 2027 | 2 articles | Viewed by 2267 | Submission Open

Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders

(This special issue belongs to the Section Clinical Pediatrics)

Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment—Second Edition

edited by Alba Scerrati and Giorgio Mantovani

submission deadline 5 Mar 2027 | 3 articles | Viewed by 3467 | Submission Open

Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis

(This special issue belongs to the Section Clinical Neurology)

Integrating Artificial Intelligence into Plastic, Reconstructive, and Aesthetic Surgery: Innovations, Challenges, and Clinical Application

edited by

Roberto Cuomo

and

Gianluca Marcaccini

submission deadline 5 Mar 2027 | 2 articles | Viewed by 3179 | Submission Open

Keywords: plastic; reconstructive; aesthetic surgery; artificial intelligence; AI in plastic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

The Atrial Fibrillation–Heart Failure Interconnection: Challenges and Innovations in Diagnosis and Treatment

edited by

Roberto De Ponti

and

Michele Golino

submission deadline 5 Mar 2027 | 1 articles | Viewed by 1941 | Submission Open

Keywords: atrial fibrillation; catheter ablation; ventricular dysfunction; myocardial remodeling; diastolic dysfunction; biomarkers; anti-arrhythmia agents; risk assessment; artificial intelligence; telemedicine

(This special issue belongs to the Section Cardiovascular Medicine)

Echocardiography in Clinical Cardiac Imaging: Advances and Emerging Applications

edited by

Marina Leitman

submission deadline 10 Mar 2027 | 2 articles | Viewed by 2591 | Submission Open

Keywords: echocardiography; cardiac Imaging; speckle-tracking echocardiography; artificial intelligence; myocardial function; valvular heart disease; precision cardiology

(This special issue belongs to the Section Cardiology)

Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside

edited by

Silvano Dragonieri

and

Andras Bikov

submission deadline 10 Mar 2027 | 3 articles | Viewed by 2354 | Submission Open

Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers

(This special issue belongs to the Section Respiratory Medicine)

Radiation Therapy: Recent Trends and Future Perspectives

edited by

Jongmoo Park

Jaehyeon Park

and Jae-won Park

submission deadline 10 Mar 2027 | 1 articles | Viewed by 823 | Submission Open

Keywords: breast reconstruction & PMRT; SBRT in oligometastatic cancer; metastasis-directed therapy; trends in modern radiotherapy techniques; palliative radiotherapy optimization; quality of life (QoL) in oncology; precision radiation oncology; artificial intelligence in radiotherapy

(This special issue belongs to the Section Oncology)

Acute Myocardial Infarction: Diagnosis and Novel Treatment Opportunities

edited by

Danilo Menichelli

and Flavio Giuseppe Biccirè

submission deadline 10 Mar 2027 | 1 articles | Viewed by 740 | Submission Open

Keywords: acute myocardial infarction; atherosclerosis; percutaneous coronary intervention; atherothrombosis; inflammation; dyslipidemia; lipid-lowering therapy

(This special issue belongs to the Section Cardiology)

Shoulder and Elbow Diseases: Advances in Diagnosis, Treatment and Rehabilitation

edited by

Mohammad Daher

Hafiz F. Kassam

and Joseph A. Abboud

submission deadline 10 Mar 2027 | 1 articles | Viewed by 378 | Submission Open

Keywords: shoulder; elbow; rotator cuff; arthritis; shoulder instability; arthroscopy; arthroplasty; tendinopathy; orthobiologics; rehabilitation; imaging

(This special issue belongs to the Section Orthopedics)

Open, Hybrid and Endovascular Repair of Visceral Artery Aneurysms: State of the Art and Clinical Perspectives

edited by

Andrea Xodo

, Francesco Squizzato and Vincenzo Vento

submission deadline 10 Mar 2027 | Viewed by 311 | Submission Open

Keywords: visceral artery aneurysms; endovascular treatment; open surgical repair; hybrid approach; covered stents; end-organ ischemia; long-term durability; patient selection

(This special issue belongs to the Section Vascular Medicine)

Contemporary Clinical Treatment and Rehabilitation of Scoliosis

edited by

Jacek Wilczyński

and Zbigniew Śliwiński

submission deadline 10 Mar 2027 | Viewed by 136 | Submission Open

Keywords: scoliosis; adolescent idiopathic scoliosis; spinal deformity; conservative treatment; physiotherapy; rehabilitation; physi-otherapeutic scoliosis-specific exercises (PSSE); postural control; spinal alignment; biomechanics; neuromuscular reha-bilitation; surface topography; raster stereography; gait analysis; musculoskeletal disorders

(This special issue belongs to the Section Orthopedics)

Artificial Intelligence and Eye Disease: 2nd Edition

edited by

Andrzej Grzybowski

Louis Arnould

and

Haoyu Chen

submission deadline 10 Mar 2027 | Viewed by 131 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; ophthalmology; eye disease; eye disorders

(This special issue belongs to the Section Ophthalmology)

Clinical Diagnosis and Management of Attention-Deficit/Hyperactivity Disorder (ADHD)

edited by

Francisco Gonzalez-Lima

submission deadline 10 Mar 2027 | Viewed by 104 | Submission Open

Keywords: ADHD; randomized controlled trials; clinical research; neurodevelopmental disorders; cognitive function; prefrontal cortex; diagnostic methods; therapeutic interventions; evidence-based medicine

(This special issue belongs to the Section Mental Health)

Robotic Surgery in Urologic Diseases: Multidisciplinary Research and Clinical Practice

edited by Donato Cannoletta

submission deadline 10 Mar 2027 | Viewed by 80 | Submission Open

Keywords: robotic surgery; urological surgery; robotic platforms

(This special issue belongs to the Section Nephrology & Urology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Mar 2027 | 2 articles | Viewed by 6904 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Atrial Fibrillation and Heart Failure: Diagnostic and Therapeutic Challenges and Breakthroughs

edited by

Silvius Alexandru Pescariu

Felix Bratosin

and

Cristian Mornos

submission deadline 15 Mar 2027 | 3 articles | Viewed by 4746 | Submission Open

Keywords: atrial fibrillation; heart failure; cardiac electrophysiology; ventricular remodelling; rhythm control; catheter abla-tion; neurohormonal activation; biomarkers; ischemia; integrated cardiovascular care

(This special issue belongs to the Section Cardiology)

Recent Clinical Advances in Esophageal Surgery

edited by

Guy Pines

, James Tankel and Harbi Khalayleh

submission deadline 15 Mar 2027 | 4 articles | Viewed by 3812 | Submission Open

Keywords: esophageal surgery; minimally invasive surgery; esophageal cancer; robotic surgery; endoscopic resection; benign esophageal disorders; paraesophageal hernia; anti-reflux surgery; motility disorders

(This special issue belongs to the Section General Surgery)

Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics

edited by Dafni Charisopoulou and

Michael Henein

submission deadline 15 Mar 2027 | 3 articles | Viewed by 3696 | Submission Open

Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure

(This special issue belongs to the Section Cardiology)

Understanding Dermatitis: Symptoms and Effective Treatment Options

edited by

Emi Sato

and Shinichi Imafuku

submission deadline 15 Mar 2027 | 1 articles | Viewed by 3678 | Submission Open

Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data

(This special issue belongs to the Section Dermatology)

Redefining Hemodialysis: Beyond Diffusion to Precision Therapy

edited by

Stefano Stuard

and Sagar Nigwekar

submission deadline 15 Mar 2027 | 1 articles | Viewed by 2631 | Submission Open

Keywords: digitalized medical governance; precision dialysis; convective clearance; advanced membranes; hemodynamic stability; artificial intelligence; digital biomarkers; personalized prescription; cardiovascular protection; patient-reported outcome measures; clinical trial emulation

(This special issue belongs to the Section Nephrology & Urology)

Minimally Invasive Cardiothoracic Surgery: Current Status and Future Perspectives

edited by

Shun-Ichiro Sakamoto

submission deadline 15 Mar 2027 | 3 articles | Viewed by 1685 | Submission Open

Keywords: aortic-preserving surgery; hybrid cardiovascular surgery; autologous tissue repair; enhanced recovery after surgery; minimally invasive cardiac surgery (MICS); geriatric surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options

edited by Przemysław Puz,

Nikolaos Grigoriadis

and

Eduardo Agüera-Morales

submission deadline 15 Mar 2027 | 3 articles | Viewed by 1594 | Submission Open

Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Epilepsy Research

edited by

Guillermo Estivill-Torrús

submission deadline 15 Mar 2027 | 2 articles | Viewed by 1413 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Glaucoma: Advances in Diagnosis, Management, and Vision Preservation

edited by

Masaki Tanito

and

Takuhei Shoji

submission deadline 15 Mar 2027 | 2 articles | Viewed by 1262 | Submission Open

Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT, micropulse, cyclophotocoagulation, etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function

(This special issue belongs to the Section Ophthalmology)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Mar 2027 | 1 articles | Viewed by 781 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

Outcomes in Pediatric Neurosurgery

edited by

Petra Klinge

and Konstantina Svokos

submission deadline 15 Mar 2027 | 1 articles | Viewed by 494 | Submission Open

Keywords: functional outcomes; pediatric neurosurgery; quality of life; innovative technologies; global neurosurgery

(This special issue belongs to the Section Clinical Pediatrics)

Delaying the Progression to Castration Resistance: Integrating Multidisciplinary Strategies and Tumor Survival Mechanisms in High-Risk Prostate Cancer

edited by Tag Keun Yoo

submission deadline 15 Mar 2027 | 1 articles | Viewed by 441 | Submission Open

Keywords: high-risk prostate cancer; oligometastasis; cytoreductive prostatectomy; multidisciplinary therapy; ADT; ARPI; docetaxel resistance; tumor survival mechanisms; CRPC progression

(This special issue belongs to the Section Oncology)

Clinical Advances and Emerging Trends in Neuropsychology

edited by

Sharon Vaisvaser

and

Tal Shafir

submission deadline 15 Mar 2027 | 1 articles | Viewed by 324 | Submission Open

Keywords: neuropsychology; affective neuroscience; social neuroscience; brain–behavior relationship; emotional processing; emotion regulation; memory; personalized mental health; therapeutic factors

(This special issue belongs to the Section Mental Health)

From Gastritis to Gastric Cancer: Challenges in Diagnosis and Long-Term Management

edited by

Zuzanna Pelc

and

Karol Rawicz-Pruszyński

submission deadline 15 Mar 2027 | Viewed by 321 | Submission Open

Keywords: gastric cancer; gastritis and H. pylori; early detection and endoscopy; multimodal treatment; molecular profiling (MSI/MMR, PD-L1, CLDN18.2, HER2)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1051-1100 on page 22 of 30.

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