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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cardiac Amyloidosis and Heart Failure: Clinical Pathophysiology, Diagnosis, and Therapeutic Strategies
edited by Ilaria Dentamaro and
submission deadline 15 Nov 2026 | 4 articles | Viewed by 4814 | Submission Open
Keywords: cardiology; cardiac heart failure; cardiac amyloidosis; cardiac imaging; cardiomyopathy
(This special issue belongs to the Section Cardiology)
Clinical Progress in Cardiovascular Surgery submission deadline 15 Nov 2026 | 2 articles | Viewed by 1168 | Submission Open
Keywords: cardiovascular surgery; CABG; valvular surgery; aortic surgery; postoperative atrial fibrillation; cardio-oncology; minimally invasive cardiac surgery; mechanical circulatory support; outcomes research; ESC-aligned cardiovascular care
(This special issue belongs to the Section Cardiovascular Medicine)
Endometrial Disorders and Pregnant Outcome: Clinical Insights and Perspectives
edited by Raffaella Di Girolamo
submission deadline 15 Nov 2026 | 1 articles | Viewed by 909 | Submission Open
Keywords: endometrial microbiome; fertility preservation; pregnancy outcome; reproductive medicine, ART
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Interventions for Cognitive Impairment and Neurological Disorders submission deadline 15 Nov 2026 | 1 articles | Viewed by 754 | Submission Open
Keywords: exercise; mental disorders; mental health; physical function; depression; anxiety; cognitive function; lifespan; physical activity
(This special issue belongs to the Section Mental Health)
Pediatric Pulmonology: Recent Developments and Emerging Trends—Second Edition
edited by Athina L. Papadopoulou
submission deadline 15 Nov 2026 | Viewed by 382 | Submission Open
Keywords: definition of breath sounds; lung–gut axis pathophysiology; disease endotypes and phenotypes; asthma management in children; bronchiolitis spectrum; pediatric bronchopulmonary dysplasia; pulmonary function testing in pediatric patients; pediatric sleep-disordered breathing; neonatal respiratory distress syndrome; childhood interstitial lung diseases; pulmonary hypertension in children; biomarkers in pediatric lung diseases; allergy and the lungs; diagnostic and therapeutic challenges in bronchoscopy; gene therapy in cystic fibrosis
(This special issue belongs to the Section Clinical Pediatrics)
Recent Management and Future Perspectives on Knee Arthroplasty
edited by
submission deadline 15 Nov 2026 | Viewed by 326 | Submission Open
Keywords: knee arthroplasty; individualized approach; implant designs; robotic-assisted; knee alignment
(This special issue belongs to the Section Orthopedics)
Emergency Ultrasound: Rapid Diagnosis and Clinical Applications
edited by
submission deadline 15 Nov 2026 | Viewed by 251 | Submission Open
Keywords: emergency ultrasound; point-of-care ultrasound (POCUS); rapid diagnostic; acute care; bedside imaging
(This special issue belongs to the Section Emergency Medicine)
Cognitive and Emotional Health in Older Adults: Recent Clinical Advances
edited by Milan Chang
submission deadline 15 Nov 2026 | Viewed by 175 | Submission Open
Keywords: activities of daily living (ADL); sarcopenia; mobility; physical activity; fall prevention; fear of falling (FOF); depres-sive symptoms; cognitive reserve; self-efficacy; life satisfaction
(This special issue belongs to the Section Geriatric Medicine)
Non-Operating Room Anesthesia
edited by Basavana Goudra
submission deadline 15 Nov 2026 | Viewed by 158 | Submission Open
Keywords: anesthesia; oxygenation; sedative agents; ventilation; airway management; hemodynamic monitoring
(This special issue belongs to the Section Anesthesiology)
Clinical Advances in Pain Management: 2nd Edition
edited by Jamal Hasoon and Omar Viswanath
submission deadline 16 Nov 2026 | Viewed by 244 | Submission Open
Keywords: postoperative pain; acute pain; chronic pain; nociceptive; analgesia; analgesics; interventional pain procedures
(This special issue belongs to the Section Anesthesiology)
Fibromyalgia: Diagnostic Progress and Therapeutic Advances submission deadline 17 Nov 2026 | 2 articles | Viewed by 2821 | Submission Open
Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS
(This special issue belongs to the Section Clinical Neurology)
Advancing the Clinical Management of Myeloproliferative Neoplasms (MPNs) submission deadline 18 Nov 2026 | 2 articles | Viewed by 1348 | Submission Open
Keywords: myeloproliferative neoplasms; targeted therapies; emerging therapies; outcomes; thrombosis; thrombosis prevention
(This special issue belongs to the Section Hematology)
Perioperative Care and Anaesthesia: Clinical Challenges and Future Perspectives
edited by
submission deadline 18 Nov 2026 | 2 articles | Viewed by 813 | Submission Open
Keywords: perioperative hemodynamic monitoring; patient blood management; perioperative bleeding and coagulopathy; cardiac anesthesia and critical care; mechanical circulatory support; goal-directed therapy; viscoelastic testing; perioperative anemia; transfusion; iron deficiency; perioperative shock
(This special issue belongs to the Section Anesthesiology)
Pediatric Dentistry: Recent Advances, Current Issues and Future Challenges submission deadline 20 Nov 2026 | 9 articles | Viewed by 29676 | Submission Open
Keywords: pediatric dentistry; recent advances; current issues; future challenges; orthodontic issues; preventive strategies; access to care disparities; behavioral management; multidisciplinary collaboration; oral health
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 20 Nov 2026 | 5 articles | Viewed by 12482 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition
edited by Botond Csiky
submission deadline 20 Nov 2026 | 3 articles | Viewed by 11724 | Submission Open
Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease
(This special issue belongs to the Section Nephrology & Urology)
Integrated Clinical Approaches to Managing Multimorbidity and Multiple Disabilities: Advances in Rehabilitation and Therapeutic Strategies
edited by
submission deadline 20 Nov 2026 | 4 articles | Viewed by 11185 | Submission Open
Keywords: heart; lung; kidney; liver; bone; brain
(This special issue belongs to the Section Clinical Rehabilitation)
Total Joint Arthroplasty: Clinical Advances and Innovations in Surgical Techniques and Rehabilitation
edited by , Marco Minelli and Federico Della Rocca
submission deadline 20 Nov 2026 | 6 articles | Viewed by 7887 | Submission Open
Keywords: total joint arthroplasty; hip replacement; knee arthroplasty; robotic-assisted surgery; minimally invasive techniques; implant design; postoperative rehabilitation; periprosthetic joint infection; surgical innovation
(This special issue belongs to the Section Orthopedics)
Innovations in Thoracic Surgery and Disease Management: Integrating Genomics, Technology, and Multidisciplinary Care submission deadline 20 Nov 2026 | 7 articles | Viewed by 7109 | Submission Open
Keywords: thoracic surgery; thoracic disease; genomic medicine; artificial intelligence; advanced imaging; multidisciplinary care; minimally invasive surgery; robotic surgery; precision medicine
(This special issue belongs to the Section Respiratory Medicine)
Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications
edited by Ioanna Koniari
submission deadline 20 Nov 2026 | 4 articles | Viewed by 6702 | Submission Open
Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system
(This special issue belongs to the Section Cardiology)
Research Progress in Pediatric Endocrinology
edited by
submission deadline 20 Nov 2026 | 3 articles | Viewed by 6482 | Submission Open
Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening
(This special issue belongs to the Section Clinical Pediatrics)
Attention-Deficit/Hyperactivity Disorder, Psychiatric Comorbidity and Substance Use Disorders: Clinical Complexity Across the Lifespan
edited by Miriam Olivola and Paola Landi
submission deadline 20 Nov 2026 | 1 articles | Viewed by 6382 | Submission Open
Keywords: ADHD; psychiatric comorbidity; substance use disorder; emotional dysregulation; impulsivity; dual diagnosis; adult ADHD; addiction vulnerability; neurodevelopmental disorders; transdiagnostic psychopathology
(This special issue belongs to the Section Mental Health)
Current Trends in Urogynecology: 3rd Edition
edited by
submission deadline 20 Nov 2026 | 5 articles | Viewed by 6016 | Submission Open
Keywords: urogynecological surgery (uterovaginal prolapse, urinary incontinence, fistulas); OAB; pharmacology; physiotherapy; LUTS
(This special issue belongs to the Section Obstetrics & Gynecology)
Acute Coronary Syndromes | Circulation Research submission deadline 20 Nov 2026 | 7 articles | Viewed by 5248 | Submission Open
Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors
(This special issue belongs to the Section Cardiology)
New Insights in Paediatric Endocrinology
edited by
submission deadline 20 Nov 2026 | 5 articles | Viewed by 5143 | Submission Open
Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns
(This special issue belongs to the Section Clinical Pediatrics)
Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition
edited by
submission deadline 20 Nov 2026 | 7 articles | Viewed by 5125 | Submission Open
Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis
(This special issue belongs to the Section Orthopedics)
Oral and Maxillofacial Surgery: Current Progress and Future Directions submission deadline 20 Nov 2026 | 5 articles | Viewed by 4191 | Submission Open
Keywords: oral and maxillofacial surgery; digital planning; head and neck surgery; reconstructive surgery; implant–prosthetic rehabilitation; oral diseases; regenerative dentistry; AI
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Insights in Maternal–Fetal Medicine
edited by Moti Gulersen
submission deadline 20 Nov 2026 | 5 articles | Viewed by 3962 | Submission Open
Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation
(This special issue belongs to the Section Obstetrics & Gynecology)
Integrated Management of Long COVID: Fatigue, Emerging Evidence, and Therapeutic Innovations
edited by
submission deadline 20 Nov 2026 | 5 articles | Viewed by 3325 | Submission Open
Keywords: long COVID; post-COVID condition; fatigue; clinical management; rehabilitation; therapeutic innovation; integrative medicine; biomarkers
(This special issue belongs to the Section Infectious Diseases)
Clinical Aspects of Return to Sport After Injuries: 2nd Edition
edited by and
submission deadline 20 Nov 2026 | 3 articles | Viewed by 3251 | Submission Open
Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine
(This special issue belongs to the Section Sports Medicine)
Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease
edited by Josuel Ora
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2765 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
The Latest Advancements in Solid Organ Transplantation
edited by Eviatar Nesher
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2638 | Submission Open
Keywords: solid organ transplantation; robotic transplant surgery; living donor transplantation; indocyanine green fluorescence imaging; delayed graft function; mixed chimerism; tolerance induction; bone marrow transplantation; islet autotransplantation; total pancreatectomy; artificial intelligence; machine learning; kidney transplantation; liver transplantation; immunosuppression
(This special issue belongs to the Section General Surgery)
Advances and Clinical Comparisons in Analgesia: Pharmacological, Non-Pharmacological, and Device-Based Approaches
edited by and
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2341 | Submission Open
Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical
(This special issue belongs to the Section Anesthesiology)
Innovations in the Treatment for Depression and Anxiety—2nd Edition
edited by
submission deadline 20 Nov 2026 | 4 articles | Viewed by 2154 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Clinical Research in Vascular Access Devices
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1907 | Submission Open
Keywords: short peripheral catheters; long peripheral catheters; midline; peripherally inserted central catheters (PICCs); femoral-inserted central catheters (FICCs); centrally inserted central catheters (CICCs); totally implantable venous access devices (TIVAD); catheter-related bloodstream infection (CRBSI); catheter-associated bloodstream infection (CABSI); central line-associated bloodstream infection (CLABSI); catheter-related thrombosis (CRT); fibroblastic sleeve; infiltration; extravasation
(This special issue belongs to the Section Vascular Medicine)
Cardiometabolic Health and Cardiovascular Outcomes: Pathophysiology to Implementation submission deadline 20 Nov 2026 | 2 articles | Viewed by 1861 | Submission Open
Keywords: cardiometabolic disease; obesity; type 2 diabetes; cardiovascular risk; morbidity; mortality; prevention
(This special issue belongs to the Section Cardiovascular Medicine)
Patient Blood Management Throughout the Hospital Pathway: Admission, Surgery, ICU, and Beyond
edited by and Kai Zacharowski
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1856 | Submission Open
Keywords: anemia; blood health; blood loss; blood transfusion; coagulopathy; critical care; hemostasis; laboratory diagnostics; patient blood management; perioperative care; point-of-care testing; transfusion medicine; thrombosis; trauma; viscoelastic testing
(This special issue belongs to the Section Intensive Care)
Colorectal Cancer: Screening, Diagnosis and Treatment
edited by and Sara De Dosso
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1781 | Submission Open
Keywords: colorectal cancer; cancer screening; early diagnosis; multidisciplinary treatment; colorectal surgery; medical oncology; precision oncology; molecular biomarkers; real-world evidence; personalized medicine; health disparities; survivorship
(This special issue belongs to the Section Oncology)
Hematopoietic Stem Cell Transplantation: Current Research and New Perspectives
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1753 | Submission Open
Keywords: allogenic transplantation; autologous transplantation; infection; GVHD; transplant related mortality; transplant complications; conditioning regimen; donor lymphocyte infusion; minimal residual disease; graft versus leukemia
(This special issue belongs to the Section Hematology)
Electroencephalography: Advances in Clinical Applications submission deadline 20 Nov 2026 | 2 articles | Viewed by 1721 | Submission Open
Keywords: electroencephalography; clinical EEG; machine learning; deep learning; seizure detection; sleep EEG; brain–computer interface; neurodegenerative disease; consciousness assessment; automated diagnosis; multimodal neu-roimaging; human-AI benchmarking
(This special issue belongs to the Section Clinical Neurology)
Cardiac MRI: Current Techniques and Future Directions
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1691 | Submission Open
Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner
(This special issue belongs to the Section Cardiology)
Periodontal Diseases: Latest Advances in Diagnosis and Therapeutic Strategies
edited by Francesco Saverio Martelli and Giada Marroncini
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1642 | Submission Open
Keywords: periodontal diseases; precision dentistry; genetic susceptibility; oral microbiome; inflammatory biomarkers; personalized therapy; multidisciplinary approach; periodontal diagnostics; host response modulation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Thromboembolic Disease and Antithrombotic Therapy: 2nd Edition
edited by Prahlad Ho
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1585 | Submission Open
Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein throm-bosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Vir-chow’s triad; post thrombotic syndrome
(This special issue belongs to the Section Hematology)
Genitourinary Infections: Current Status and Emerging Challenges
edited by and George I. Kaparos
submission deadline 20 Nov 2026 | 4 articles | Viewed by 1584 | Submission Open
Keywords: genital tract infections; sexually transmitted infections; vaginal infections; urinary tract infections; recurrent infections; diagnostic challenges; antimicrobial resistance
(This special issue belongs to the Section Infectious Diseases)
Acute Management and Surgical Strategies in Orthopedic Trauma
edited by Hyung Keun Song
submission deadline 20 Nov 2026 | 3 articles | Viewed by 1525 | Submission Open
Keywords: orthopedic trauma; acute care; trauma surgery; damage control orthopedics; early definitive fixation; surgical timing; polytrauma; pelvic fracture; acetabular fracture; perioperative management; complications; clinical outcomes; trauma systems
(This special issue belongs to the Section Orthopedics)
Challenges in Emergency Medicine
edited by and Gregor Prosen
submission deadline 20 Nov 2026 | 3 articles | Viewed by 1372 | Submission Open
Keywords: in-hospital and prehospital care; care of the critically ill; resuscitation and post-resuscitation management; point-of-care ultrasound; emergency surgical and procedural interventions; digitalization and emerging technolo-gies; emergency medicine
(This special issue belongs to the Section Emergency Medicine)
Digital Mental Health and Artificial Intelligence: Clinical Perspectives and Patient Safety
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1332 | Submission Open
Keywords: mental health care; telepsychiatry; telepsychotherapy; patient safety; health care data; clinical practice; digital mental health interventions; artificial intelligence in psychiatry; digital trust human–robot interactions; social networks
(This special issue belongs to the Section Mental Health)
Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions
edited by Halina Cichoz-Lach and
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1166 | Submission Open
Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut–liver axis; organ-to-organ crosstalk
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
IBD Surgery and Short Bowel Syndrome
edited by and Paola Caprino
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1120 | Submission Open
Keywords: abdominal surgery; minimally invasive surgery; robotic surgery; complex abdominal surgery; intestinal failure; short bowel syndrome; perioperative management; surgical outcomes; multidisciplinary care; surgical treatment of inflammatory bowel disease (IBD)
(This special issue belongs to the Section General Surgery)
Clinical Updates on Cardiac Arrhythmias submission deadline 20 Nov 2026 | 1 articles | Viewed by 1107 | Submission Open
Keywords: clinical electrophysiology; inherited arrhythmia syndromes; arrhythmias in structural heart disease; catheter ablation; device-based therapy
(This special issue belongs to the Section Cardiology)
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