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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 31 Jul 2025 | Viewed by 175 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Disorders of Consciousness in Ischemic Stroke: Evaluation, Management and Prognostic Implications

edited by

Shraddha Mainali

submission deadline 31 Jul 2025 | Viewed by 167 | Submission Open

Keywords: disorders of consciousness; ischemic stroke; prognosis; coma; neuroprognostication

(This special issue belongs to the Section Clinical Neurology)

Haemophilia: Current Treatment and Clinical Outcomes, Challenges and Opportunities: 2nd Edition

edited by

Ezio Zanon

submission deadline 31 Jul 2025 | Viewed by 142 | Submission Open

Keywords: haemophilia A and B; FVIII EHL; FIX EHL; prophylaxis; emicizumab; health-related quality of life; population pharmacokinetics

(This special issue belongs to the Section Hematology)

State of the Art in Surgical Treatment for Colorectal Cancer

edited by Saulius Švagždys

submission deadline 31 Jul 2025 | Viewed by 123 | Submission Open

Keywords: laparoscopic and robotic surgery; endoscopic and minimally invasive surgery; colorectal cancer; energy devices; staplers

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Shaping Modern Gastroenterology: Bridging Advancements in Digestive Endoscopy and Clinical Research

edited by Manuele Furnari and Stefano Kayali

submission deadline 3 Aug 2025 | Viewed by 149 | Submission Open

Keywords: digestive endoscopy; gastrointestinal disorders; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); therapeutic endoscopy; artificial intelligence; pancreatic and biliary diseases; small bowel pathology; early neoplastic lesions; inflammatory bowel diseases (IBDs); translational gastroenterology; endoscopic submucosal dissection (ESD); per-oral endoscopic myotomy (POEM); endoscopic imaging; gastrointestinal pathophysiology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets

edited by Beata Kasztelan-Szczerbinska and Halina Cichoż-Lach

submission deadline 5 Aug 2025 | 2 articles | Viewed by 2708 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); non-alcoholic fatty liver disease (NAFLD); hepatic steatosis; multiorgan metabolic interactions; liver-related morbidity; liver-related mortality; lipid metabolism; cardiovascular metabolic complications; metabolic dysfunction-related cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries

edited by

Giovanni Barassi

, Pier Enrico Gallenga and

Roberta Di Pietro

submission deadline 5 Aug 2025 | 1 articles | Viewed by 981 | Submission Open

Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Artificial Intelligence in Urology

edited by

Theodoros Tokas

submission deadline 10 Aug 2025 | 5 articles | Viewed by 5746 | Submission Open

Keywords: artificial intelligence; deep learning; artificial neural networks; computer; AI; machine learning

(This special issue belongs to the Section Nephrology & Urology)

State of the Art: Catheter Ablation of Atrial Fibrillation

edited by

Roberto Menè

and Cinzia Monaco

submission deadline 10 Aug 2025 | 3 articles | Viewed by 5343 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulsed-field ablation; supraventricular arrhythmias; atrial substrate

(This special issue belongs to the Section Cardiovascular Medicine)

The Clinical Role of Imaging in Lung Diseases

edited by

Isabelle Fitton

and Claire Van Ngoc Ty

submission deadline 10 Aug 2025 | 4 articles | Viewed by 3723 | Submission Open

Keywords: lung screening; lung cancer; acute respiratory distress; pulmonary embolism; chronic obstructive pulmonary disease; imaging

(This special issue belongs to the Section Respiratory Medicine)

Immune Dysregulation in Inborn Errors of Immunity: From Allergy to Autoimmunity and Lymphoproliferation

edited by

Giorgio Costagliola

submission deadline 10 Aug 2025 | 2 articles | Viewed by 3028 | Submission Open

Keywords: immune dysregulation; immunodeficiency; autoimmunity; allergy; lymphoproliferation; inborn errors of immunity

(This special issue belongs to the Section Immunology)

Clinical Updates and Perspectives of Implant Dentistry

edited by

Renzo Guarnieri

and

Rodolfo Reda

submission deadline 13 Aug 2025 | 1 articles | Viewed by 4240 | Submission Open

Keywords: osseointegration; soft tissue integration; peri-implant diseases

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management of Patients with Heart Failure—2nd Edition

edited by

Tudoran Cristina

submission deadline 13 Aug 2025 | 6 articles | Viewed by 3605 | Submission Open

Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; life style changes; diagnosis of heart failure

(This special issue belongs to the Section Cardiovascular Medicine)

Trends and Prospects in Shoulder and Elbow Surgery

edited by Lorenzo Diaz Balzani, Erika Albo,

Rocco Papalia

and

Vincenzo Denaro

submission deadline 14 Aug 2025 | 5 articles | Viewed by 4978 | Submission Open

Keywords: shoulder; elbow; arthroplasty; arthroscopy; rehabilitation; trauma; minimally invasive; regenerative medicine; implant technology

(This special issue belongs to the Section Orthopedics)

Amyloid: From Heart to Brain

edited by

Filippos Triposkiadis

Andrew Xanthopoulos

and

Alexandros Briasoulis

submission deadline 15 Aug 2025 | 4 articles | Viewed by 3862 | Submission Open

Keywords: amyloid; heart; brain; interactions; small vessel disease; takotsubo; Alzheimer’ s disease

(This special issue belongs to the Section Cardiology)

Sepsis: Current Updates and Perspectives

edited by Ecaterina Scarlatescu

submission deadline 15 Aug 2025 | 2 articles | Viewed by 2996 | Submission Open

Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies

(This special issue belongs to the Section Intensive Care)

Novel Therapeutic Strategies for Acute Myeloid Leukemia

edited by Giovangiacinto Paterno and

Maria Ilaria Del Principe

submission deadline 15 Aug 2025 | 2 articles | Viewed by 2382 | Submission Open

Keywords: acute myeloid leukemia; novel treatments; supportive care; quality of life; patients’ outcomes; targeted therapy

(This special issue belongs to the Section Hematology)

Otolaryngology—Head and Neck Surgery: Current Trends and Challenges

edited by

Michele Gaffuri

and Lorenzo Maria Gaini

submission deadline 15 Aug 2025 | 3 articles | Viewed by 1446 | Submission Open

Keywords: minimally invasive surgery; endoscopy; exoscopy; airway surgery; salivary glands diseases; otitis media; pediatric otolaryngology; head and neck surgery

(This special issue belongs to the Section Otolaryngology)

Oral and Maxillofacial Radiology: Clinical Progress and New Directions

edited by Zbigniew Serafin and

Wojciech Kazimierczak

submission deadline 15 Aug 2025 | 3 articles | Viewed by 1404 | Submission Open

Keywords: artificial intelligence (AI); computed-assisted diagnosis (CAD); cone beam computed tomography (CBCT); convolutional neural network (CNN); computed tomography (CT); magnetic resonance (MR); PET-CT

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Cardiac Electrophysiology: Focus on Clinical Practice

edited by

Andreas Müssigbrodt

submission deadline 15 Aug 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: cardiomyopathy; arrhythmia; heart rhythm; atrial fibrillation; ventricular tachycardia; sudden cardiac death; mapping; ablation; pulsed field ablation (PFA); device; pacemaker; left bundle branch area pacing (LBBAP); conduction system pacing (CSP); implantable cardioverter-defibrillator (ICD); leadless pacing; extraction

(This special issue belongs to the Section Cardiology)

Application of Magnetic Resonance Imaging (MRI) in the Diagnosis, Staging and Follow-Up of Oncological Diseases

edited by

Matteo Bonatti

submission deadline 15 Aug 2025 | 1 articles | Viewed by 775 | Submission Open

Keywords: MRI; cancer; oncology; diagnosis; staging; follow-up; radiomics

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Diagnosis and Treatment for Bone Tumor

edited by Antonio Ziranu and Luigi Cianni

submission deadline 15 Aug 2025 | 1 articles | Viewed by 505 | Submission Open

Keywords: bone tumor; oncology; osteosarcoma; chondrosarcoma; megaprosthesis; bone resection; chemotherapy; radiotherapy; sarcoma; custom-made

(This special issue belongs to the Section Orthopedics)

The Role of Cardiac Rehabilitation After Myocardial Infarction, Coronary Artery Bypass Surgery, and in Other Cardiac Diseases

edited by

Aneta Aleksova

and

Milijana Janjušević

submission deadline 15 Aug 2025 | Viewed by 231 | Submission Open

Keywords: cardiac rehabilitation; coronary artery disease; myocardial infarction; coronary artery bypass surgery; heart failure; ventricular assist device; heart transplantation; cardiomyopathies; cardiac remodeling; illness perception; treatment adherence; gender difference; biomarkers; endothelial function

(This special issue belongs to the Section Cardiology)

Advances in Traumatic Brain Injury: Causes and Recovery

edited by Antonio Bonora

submission deadline 15 Aug 2025 | Viewed by 145 | Submission Open

Keywords: mild traumatic brain injury; TBI; brain injuries; neuroimaging; rehabilitation

(This special issue belongs to the Section Brain Injury)

Clinical Management and Rehabilitation of Spinal Cord Injury

edited by Tsunehiko Konomi

submission deadline 20 Aug 2025 | 11 articles | Viewed by 24735 | Submission Open

Keywords: spinal cord injury; rehabilitation; diagnosis and prognosis; comprehensive management; social support

(This special issue belongs to the Section Orthopedics)

Clinical Aspects of Return to Sport After Injuries

edited by

Anna Mika

and

Łukasz Oleksy

submission deadline 20 Aug 2025 | 6 articles | Viewed by 18601 | Submission Open

Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine

(This special issue belongs to the Section Sports Medicine)

Gastrointestinal Cancer: Outcomes and Therapeutic Management

edited by Maximos Frountzas

submission deadline 20 Aug 2025 | 8 articles | Viewed by 13735 | Submission Open

Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm

(This special issue belongs to the Section Oncology)

Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases

edited by

Reem Hanna

submission deadline 20 Aug 2025 | 5 articles | Viewed by 10770 | Submission Open

Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction

Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research

edited by

Andrew Fu Wah Ho

submission deadline 20 Aug 2025 | 5 articles | Viewed by 8507 | Submission Open

Keywords: cardiovascular emergencies; neurovascular emergencies; stroke; cardiac arrest; acute myocardial infarction

(This special issue belongs to the Section Cardiovascular Medicine)

Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation

edited by

Katja E. Wartenberg

and Lori Shutter

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7340 | Submission Open

Keywords: traumatic brain injury; neuromonitoring; neurocritical care; neurorehabilitation; secondary injury; outcome; prognostication

(This special issue belongs to the Section Brain Injury)

Recent Developments in Gynecological Endocrinology

edited by

Błażej Męczekalski

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6411 | Submission Open

Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause

(This special issue belongs to the Section Obstetrics & Gynecology)

Frailty in the Elderly: Risk Factors, Prevention and Clinical Management

edited by

Gad Segal

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5362 | Submission Open

Keywords: sarcopenia; frailty; elderly; geriatrics; personalized medicine

(This special issue belongs to the Section Epidemiology & Public Health)

New Advances in Prenatal Diagnosis and Newborn Screening

edited by

Zoltan Kozinszky

and

Andrea Suranyi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4743 | Submission Open

Keywords: sonographic parameters; molecular markers; extravillous and villous trophoblasts; perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions

(This special issue belongs to the Section Obstetrics & Gynecology)

Interstitial Lung Disease: From Diagnosis to Treatment

edited by

Takeshi Saraya

and Tomohisa Baba

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3647 | Submission Open

Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds

(This special issue belongs to the Section Respiratory Medicine)

Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections

edited by

Juan J. Segura-Egea

and

Daniel Cabanillas-Balsera

submission deadline 20 Aug 2025 | 5 articles | Viewed by 3404 | Submission Open

Keywords: dentistry; endodontics; apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Kidney Transplantation

edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López

submission deadline 20 Aug 2025 | 4 articles | Viewed by 3258 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Salivary Gland Disorders

edited by Masao Yagi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 2261 | Submission Open

Keywords: salivary gland tumour; parotidectomy; nerve monitoring; molecular-targeted therapy; immunotherapy

(This special issue belongs to the Section Otolaryngology)

Liver Transplantation: Current Hurdles and Future Perspectives

edited by

Gabriele Spoletini

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2075 | Submission Open

Keywords: machine perfusion; donation after circulatory death; liver preservation; living donation; acute-on-chronic liver failure; frailty; liver malignancies; surgical technique; liver transplant recipient care; immunosuppression

(This special issue belongs to the Section General Surgery)

Multiple Sclerosis: Prediction, Diagnosis and Treatment

edited by Rosaria Sacco

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2027 | Submission Open

Keywords: neurological diseases; multiple sclerosis; prodromal symptoms; diagnosis; treatment

(This special issue belongs to the Section Clinical Neurology)

State of the Art in Invasive Vascular Interventions (Second Edition)

edited by

Edit Dósa

and Luca Mezzetto

submission deadline 20 Aug 2025 | 3 articles | Viewed by 1782 | Submission Open

Keywords: coronary artery interventions; non-coronary artery cardiac interventions; open surgical cardiac procedures; endo-vascular interventions; open surgical vascular procedures

(This special issue belongs to the Section Vascular Medicine)

Advancements and Challenges in Managing Hepato-Pancreato-Biliary Cancers

edited by

Alessandro D. Mazzotta

and Niccolò Petrucciani

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1378 | Submission Open

Keywords: liver; pancreas; HPB technology; artificial intelligence for HPB; surgical oncology; MIS

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Juvenile Idiopathic Arthritis (JIA): Diagnosis, Treatment and Latest Updates

edited by

Rita Consolini

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1312 | Submission Open

Keywords: juvenile idiopathic arthritis; pathophysiology; genetic predisposition; immunologic abnormalities; diagnosis; treatment; outcome

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Gastrointestinal Inflammation

edited by

Ivana Jukic

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1299 | Submission Open

Keywords: Helicobacter pylori; antibiotic resistance; COVID-19 pandemic; post-COVID era; inflammatory bowel diseases; acute gastrointestinal infections; SARS-COV-2 infection; celiac disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates in Trauma and Emergency Medicine

edited by Yong-Soo Cho and Hyun Ho Ryu

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1013 | Submission Open

Keywords: emergency medicine; epidemiology; cardiovascular disease

(This special issue belongs to the Section Emergency Medicine)

Mental Disorders, Cognitive Impairment and Dementia Among Older Adults

edited by

Agustín Aibar Almazán

submission deadline 20 Aug 2025 | 1 articles | Viewed by 979 | Submission Open

Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function

(This special issue belongs to the Section Geriatric Medicine)

Cardio-Oncology: Novel Concepts in Diagnosis, Prevention and Treatment of Cardiotoxicity, from Gender Differences and Beyond (Second Edition)

edited by

Sabina Gallina

and

Valentina Bucciarelli

submission deadline 20 Aug 2025 | 1 articles | Viewed by 977 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; gender medicine; chemotherapy; radiotherapy; immune and targeted therapeutics; physical activity; quality of life

(This special issue belongs to the Section Cardiovascular Medicine)

Neurosurgery: Recent Advances and New Perspectives in Skull Base Approaches

edited by Sèbastien Froelich and Matteo De Simone

submission deadline 20 Aug 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: skull base; neuroanatomy; tumors; augmented reality; ETOA; EEA; exoscopy; endoscopy; multi-portal approaches

(This special issue belongs to the Section Clinical Neurology)

Surgical Precision: The Impact of AI and Robotics in General Surgery

edited by Tamara M. H. Gall

submission deadline 20 Aug 2025 | Viewed by 286 | Submission Open

Keywords: robotic surgery; artificial intelligence in surgery; surgical training; AR in surgery; 3D imaging; surgical navigation

(This special issue belongs to the Section General Surgery)

Diabetic Nephropathy: Advances in Pathogenesis and Novel Therapies

edited by Meritxell Ibernon

submission deadline 20 Aug 2025 | Viewed by 286 | Submission Open

Keywords: pathogenesis of diabetic nephropathy; novel therapies; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification

(This special issue belongs to the Section Nephrology & Urology)

Non-Invasive Respiratory Support: Current Insights and Future Directions

edited by Giovanni Misseri and

Cesare Gregoretti

submission deadline 20 Aug 2025 | Viewed by 196 | Submission Open

Keywords: respiratory failure; high-flow nasal cannula (HFNC); noninvasive ventilation (NIV); noninvasive positive pressure ventilation (NPPV); hypoxia; perioperative care; weaning; ICU; respiratory care; respiratory physiology; pneumology; home-care ventilation; artificial intelligence; personalized medicine

(This special issue belongs to the Section Respiratory Medicine)

Displaying special issue 151-200 on page 4 of 28.

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