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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Next-Generation Abdominal Surgery: Personalized, Minimally Invasive, and Data-Driven Care submission deadline 25 Oct 2026 | Viewed by 227 | Submission Open
Keywords: abdominal surgery; minimally invasive surgery; laparoscopy; robotic surgery; precision surgery; artificial intelli-gence; machine learning; surgical imaging; fluorescence-guided surgery (ICG); image-guided navigation; enhanced recovery after surgery (ERAS); prehabilitation; postoperative complications; risk stratification; outcomes research
(This special issue belongs to the Section General Surgery)
Plasma Cell Dyscrasias in the Clinic: Refining Screening, Diagnosis, and Laboratory Monitoring
edited by Gurmukh Singh
submission deadline 25 Oct 2026 | Viewed by 202 | Submission Open
Keywords: multiple myeloma; monoclonal gammopathies; plasma cell neoplastic disorders; hematology; hematological malignant tumors
(This special issue belongs to the Section Clinical Laboratory Medicine)
Emerging Trends and Innovative Strategies in Lumbar Spine Surgery
edited by
submission deadline 26 Oct 2026 | 1 articles | Viewed by 475 | Submission Open
Keywords: lumbar spine surgery; minimally invasive spine surgery (MISS); spinal instrumentation and fusion; robotic-assisted surgery; navigation in spine surgery; interbody fusion techniques; perioperative management; surgical outcomes and complications; degenerative disc disease; spinal stenosis
(This special issue belongs to the Section Orthopedics)
Sports Cardiology: Current Status and Future Challenges
edited by Giuseppe Di Gioia
submission deadline 27 Oct 2026 | 2 articles | Viewed by 2248 | Submission Open
Keywords: sports cardiology; athlete’s heart; cardiac remodeling; sudden cardiac death prevention; advanced cardiac imaging; cardiopulmonary exercise testing (CPET); myocardial and atrial strain; arrhythmia risk stratification; wearable technologies and digital health; precision medicine in sports
(This special issue belongs to the Section Cardiology)
New Insights into Head and Neck Surgery—2nd Edition submission deadline 28 Oct 2026 | 4 articles | Viewed by 9112 | Submission Open
Keywords: otorhinolaryngology; head and neck surgery; ear surgery; sinonasal surgery; skull base surgery; salivary gland surgery; thyroid gland surgery; head and neck cancer surgery
(This special issue belongs to the Section General Surgery)
Clinical Novel Research in the Management of Cardiac Arrest
edited by Giovanni Babini and
submission deadline 28 Oct 2026 | 2 articles | Viewed by 2051 | Submission Open
Keywords: cardiac arrest; post-cardiac arrest syndrome; resuscitation; temperature control; target temperature management; neuroprotection; neuroprognostication; defibrillation; extracorporeal life support
(This special issue belongs to the Section Cardiology)
Clinical Advances in Cardiovascular Interventions: Second Edition
edited by
submission deadline 28 Oct 2026 | 2 articles | Viewed by 1636 | Submission Open
Keywords: coronary artery disease; myocardial infarction; cardiovascular imaging; microvascular disease; heart failure; atrial fibrillation; ventricular arrhythmias; cardiac implantable electronic device; valvular heart disease and treatment; peripheral arterial disease
(This special issue belongs to the Section Cardiology)
Preoperative Optimization in Cardiac Surgery
edited by
submission deadline 30 Oct 2026 | 3 articles | Viewed by 8121 | Submission Open
Keywords: preoperative optimization; cardiac surgery; risk assessment; comorbid conditions; multidisciplinary collaboration; perioperative risks; cardiovascular evaluation
(This special issue belongs to the Section Cardiology)
Advances in Cardiovascular Computed Tomography (CT)
edited by
submission deadline 30 Oct 2026 | 6 articles | Viewed by 4957 | Submission Open
Keywords: computed tomography angiography; cardiovascular imaging; contrast media; spectral computed tomography; quantitative imaging; coronary artery disease; aortic disease; pulmonary embolism; structural heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management for Anesthesia Critical Care
edited by Gianluca Zani
submission deadline 30 Oct 2026 | 2 articles | Viewed by 2162 | Submission Open
Keywords: anesthesia; critical care medicine; clinical management; critically ill patients; organ failure; organ dysfunction; per-sonalized therapy; outcome; technical skills; non-technical skills
(This special issue belongs to the Section Anesthesiology)
Therapeutic Strategies for Obesity–Metabolic Syndrome–Diabetes Continuum
edited by Jana Makuc and
submission deadline 30 Oct 2026 | 3 articles | Viewed by 1153 | Submission Open
Keywords: obesity; metabolic syndrome; type 2 diabetes mellitus; multi-receptor agonists; adipose tissue dysfunction; metabolic surgery; chrononutrition; gut-metabolism axis; metabolic phenotyping; MASLD
(This special issue belongs to the Section Endocrinology & Metabolism)
Personalized Medicine in Dermatology: Current Status and Challenges submission deadline 31 Oct 2026 | 2 articles | Viewed by 2671 | Submission Open
Keywords: psoriasis; quality of life; acne; hidradenitis suppurativa; biotechnological therapies; personalized medicine; autoimmune skin diseases
(This special issue belongs to the Section Dermatology)
Innovations in Geriatric Care: Managing Chronic Diseases and Emerging Challenges in an Aging World
edited by and Gianluigi Cuomo
submission deadline 31 Oct 2026 | 3 articles | Viewed by 2096 | Submission Open
Keywords: geriatric; frailty; integrated care; digital health; rehabilitation; comprehensive geriatric assessment; functional capacity
(This special issue belongs to the Section Geriatric Medicine)
New Insights in Diagnosis, Symptomatology, and Therapy in Schizophrenia and Schizoaffective Disorders
edited by Felix-Martin Werner and Arturo Mangas
submission deadline 31 Oct 2026 | 1 articles | Viewed by 526 | Submission Open
Keywords: schizophrenia; schizoaffective disorder; paranoia; acoustic hallucinations; positive schizophrenia symptoms; negative schizophrenia symptoms; second-generation antipsychotic drugs; risperidone; clozapine; cariprazine; xanomeline combined with trospium
(This special issue belongs to the Section Mental Health)
The Hidden Threat: Nonobstructive Coronary Artery Disease in Cardiovascular Health
edited by
submission deadline 31 Oct 2026 | Viewed by 236 | Submission Open
Keywords: non-obstructive coronary artery disease; coronary microvascular dysfunction; endothelial dysfunction; vasospastic angina; ischemic heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Perspectives and Advances in Pharmacology in Pregnancy and Lactation
edited by Gregory W. Kirschen
submission deadline 31 Oct 2026 | Viewed by 228 | Submission Open
Keywords: pharmacokinetics; pharmacodynamics; pharmacovigilance; clinical trials; drug safety monitoring; breastfeeding; placental transfer; fetal development; neonatal outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Pioneering the Future: AI and Innovation in Endometriosis, Adenomyosis and Adenomyoma Care
edited by , Alan DeCherney and Jeannette Lager
submission deadline 1 Nov 2026 | Viewed by 255 | Submission Open
Keywords: endometriosis; adenomyosis; adenomyoma; artificial intelligence in medicine; minimally invasive surgery; robotic surgery; surgical innovation; biomarkers and molecular diagnostics; fertility and reproductive outcomes; chronic pelvic pain
(This special issue belongs to the Section Obstetrics & Gynecology)
Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) and Concomitant Illnesses: Diagnostic and Therapeutic Implications
edited by Kamran Qureshi and Lewis Frey
submission deadline 5 Nov 2026 | 5 articles | Viewed by 6424 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); chronic liver diseases; metabolic syndrome; viral hepatitis; autoimmune liver diseases
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Insights into Pediatric Rheumatology
edited by and Maria Alessio
submission deadline 5 Nov 2026 | Viewed by 338 | Submission Open
Keywords: pediatric rheumatology; pediatric autoimmune diseases; juvenile idiopathic arthritis; macrophage activation syndrome; autoinflammatory syndromes; juvenile dermatomyositis; childhood-onset systemic lupus erythematosus; juvenile systemic and localized sclerosis; pediatric vasculitides
(This special issue belongs to the Section Clinical Pediatrics)
Musculoskeletal Pain: Clinical Management Updates submission deadline 10 Nov 2026 | 5 articles | Viewed by 6555 | Submission Open
Keywords: musculoskeletal pain; chronic pain; gait assessment; musculoskeletal disorders; patellofemoral pain
(This special issue belongs to the Section Clinical Rehabilitation)
COVID-19 and Endocrine Complications
edited by
submission deadline 10 Nov 2026 | 4 articles | Viewed by 6233 | Submission Open
Keywords: adrenal; ACE2; diabetes; gonads; pituitary; SARS-CoV-2; thyroid
(This special issue belongs to the Section Endocrinology & Metabolism)
New Clinical Advances in Depressive Disorders and Treatment-Resistant Depression
edited by Giacomo d'Andrea and
submission deadline 10 Nov 2026 | 3 articles | Viewed by 5110 | Submission Open
Keywords: treatment-resistant depression; MDD; ketamine; esketamine; rTMS; psylocibin; bipolar depression; clinical pheno-typing; precision psychiatry; biomarkers
(This special issue belongs to the Section Mental Health)
Precision and Innovation in Spine Surgery: Advanced Techniques for Spinal Disorders
edited by
submission deadline 10 Nov 2026 | 4 articles | Viewed by 2274 | Submission Open
Keywords: minimally invasive spine surgery; endoscopic spine surgery; motion preservation; disc arthroplasty; anterior lumbar interbody fusion; robotic spine surgery; spinal navigation; spinal deformity correction; degenerative disc disease; enhanced recovery after spine surgery; artificial intelligence in spine surgery; dynamic stabilization
(This special issue belongs to the Section Orthopedics)
Revolutionizing Arrhythmia Therapy: Novel Approaches in Pacing and Defibrillation submission deadline 10 Nov 2026 | 1 articles | Viewed by 1125 | Submission Open
Keywords: cardiac resynchronization therapy; conduction system pacing; left bundle branch area pacing; S-ICD; EV-ICD
(This special issue belongs to the Section Cardiology)
Latest Updates on Liver Surgery, Liver Regeneration, and Liver Transplantation
edited by Ivan Romic and Goran Pavlek
submission deadline 10 Nov 2026 | 1 articles | Viewed by 1121 | Submission Open
Keywords: liver surgery; transplant; regeneration; oncology; liver regeneration
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Musculoskeletal Disorders and Functional Rehabilitation: Innovations, Challenges and Future Directions submission deadline 10 Nov 2026 | 1 articles | Viewed by 1110 | Submission Open
Keywords: musculoskeletal disorders; functional rehabilitation; biomechanics; artificial intelligence; wearable sensors; digital biomarkers; personalised rehabilitation; digital health; mobility outcome; gait
(This special issue belongs to the Section Orthopedics)
Innovations in Knee Arthroplasty: Implants, Alignment, and Technology submission deadline 10 Nov 2026 | 1 articles | Viewed by 751 | Submission Open
Keywords: knee arthroplasty; implant design; implant materials; alignment strategies; robotics in arthroplasty; soft tissue balancing; computer-assisted surgery; tribology; patient-reported outcomes; revision knee arthroplasty; survivorship and registry data
(This special issue belongs to the Section Orthopedics)
Advances and Emerging Trends in Maternal–Fetal Medicine: From Diagnostics to Fetal Therapy
edited by Isabella Fabietti
submission deadline 10 Nov 2026 | Viewed by 619 | Submission Open
Keywords: maternal–fetal medicine; high-risk pregnancy; prenatal diagnosis; fetal therapy and surgery; fetal growth restriction; placental disorders; preterm birth; biomarkers; genomics; precision medicine; artificial intelligence in obstetrics
(This special issue belongs to the Section Obstetrics & Gynecology)
Innovative Therapies for Neurological Disorders
edited by Natalia Szejko
submission deadline 10 Nov 2026 | Viewed by 295 | Submission Open
Keywords: neurological disorders; innovative therapies; neuromodulation; digital therapeutics; precision medicine; neuroreha-bilitation; movement disorders; neurodegenerative diseases; functional neurological disorders; translational neuro-science
(This special issue belongs to the Section Clinical Neurology)
Targeted Therapy for Amyotrophic Lateral Sclerosis
edited by Annemarie Hübers
submission deadline 10 Nov 2026 | Viewed by 245 | Submission Open
Keywords: amyotrophic lateral sclerosis; targeted therapy; motor neuron disease; neurodegeneration; disease-modifying therapy
(This special issue belongs to the Section Clinical Neurology)
Decoding Male Reproductive Health: Clinical and Laboratory Perspectives
edited by and Ana Segura
submission deadline 10 Nov 2026 | Viewed by 219 | Submission Open
Keywords: male reproductive health; male infertility; andrology; laboratory diagnosis; semen analysis
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Clinical Advancements and Breakthroughs in Heart Failure and Transplant Cardiology
edited by David Snipelisky
submission deadline 10 Nov 2026 | Viewed by 202 | Submission Open
Keywords: heart failure; cardiac transplantation; mechanical circulatory support; advanced heart failure; left ventricular assist devices; cardiomyopathies
(This special issue belongs to the Section Cardiology)
Perioperative and Glycemic Control in General Surgery
edited by
submission deadline 10 Nov 2026 | Viewed by 192 | Submission Open
Keywords: perioperative glycemic control; hypoglycemia prevention; continuous glucose monitoring; ERAS; GLP-1 receptor agonists; SGLT-2 inhibitors; surgical stress response; insulin therapy; patient quality of life; metabolic surgery
(This special issue belongs to the Section General Surgery)
Occupational Health: Current Status and Future Challenges submission deadline 12 Nov 2026 | 2 articles | Viewed by 1831 | Submission Open
Keywords: occupational health; future challenges; work-related diseases; workplace prevention; psychosocial risks; workers’ well-being; occupational safety; digitalization at work
(This special issue belongs to the Section Epidemiology & Public Health)
Cardiac Amyloidosis and Heart Failure: Clinical Pathophysiology, Diagnosis, and Therapeutic Strategies
edited by Ilaria Dentamaro and
submission deadline 15 Nov 2026 | 4 articles | Viewed by 5352 | Submission Open
Keywords: cardiology; cardiac heart failure; cardiac amyloidosis; cardiac imaging; cardiomyopathy
(This special issue belongs to the Section Cardiology)
Clinical Progress in Cardiovascular Surgery submission deadline 15 Nov 2026 | 2 articles | Viewed by 1304 | Submission Open
Keywords: cardiovascular surgery; CABG; valvular surgery; aortic surgery; postoperative atrial fibrillation; cardio-oncology; minimally invasive cardiac surgery; mechanical circulatory support; outcomes research; ESC-aligned cardiovascular care
(This special issue belongs to the Section Cardiovascular Medicine)
Endometrial Disorders and Pregnant Outcome: Clinical Insights and Perspectives
edited by Raffaella Di Girolamo
submission deadline 15 Nov 2026 | 1 articles | Viewed by 1049 | Submission Open
Keywords: endometrial microbiome; fertility preservation; pregnancy outcome; reproductive medicine, ART
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Interventions for Cognitive Impairment and Neurological Disorders submission deadline 15 Nov 2026 | 1 articles | Viewed by 900 | Submission Open
Keywords: exercise; mental disorders; mental health; physical function; depression; anxiety; cognitive function; lifespan; physical activity
(This special issue belongs to the Section Mental Health)
Pediatric Pulmonology: Recent Developments and Emerging Trends—Second Edition
edited by Athina L. Papadopoulou
submission deadline 15 Nov 2026 | 1 articles | Viewed by 731 | Submission Open
Keywords: definition of breath sounds; lung–gut axis pathophysiology; disease endotypes and phenotypes; asthma management in children; bronchiolitis spectrum; pediatric bronchopulmonary dysplasia; pulmonary function testing in pediatric patients; pediatric sleep-disordered breathing; neonatal respiratory distress syndrome; childhood interstitial lung diseases; pulmonary hypertension in children; biomarkers in pediatric lung diseases; allergy and the lungs; diagnostic and therapeutic challenges in bronchoscopy; gene therapy in cystic fibrosis
(This special issue belongs to the Section Clinical Pediatrics)
Non-Operating Room Anesthesia
edited by Basavana Goudra
submission deadline 15 Nov 2026 | 1 articles | Viewed by 367 | Submission Open
Keywords: anesthesia; oxygenation; sedative agents; ventilation; airway management; hemodynamic monitoring
(This special issue belongs to the Section Anesthesiology)
Recent Management and Future Perspectives on Knee Arthroplasty
edited by
submission deadline 15 Nov 2026 | Viewed by 349 | Submission Open
Keywords: knee arthroplasty; individualized approach; implant designs; robotic-assisted; knee alignment
(This special issue belongs to the Section Orthopedics)
Emergency Ultrasound: Rapid Diagnosis and Clinical Applications
edited by
submission deadline 15 Nov 2026 | Viewed by 270 | Submission Open
Keywords: emergency ultrasound; point-of-care ultrasound (POCUS); rapid diagnostic; acute care; bedside imaging
(This special issue belongs to the Section Emergency Medicine)
Cognitive and Emotional Health in Older Adults: Recent Clinical Advances
edited by Milan Chang
submission deadline 15 Nov 2026 | Viewed by 197 | Submission Open
Keywords: activities of daily living (ADL); sarcopenia; mobility; physical activity; fall prevention; fear of falling (FOF); depres-sive symptoms; cognitive reserve; self-efficacy; life satisfaction
(This special issue belongs to the Section Geriatric Medicine)
Clinical Advances in Pain Management: 2nd Edition
edited by Jamal Hasoon and Omar Viswanath
submission deadline 16 Nov 2026 | Viewed by 271 | Submission Open
Keywords: postoperative pain; acute pain; chronic pain; nociceptive; analgesia; analgesics; interventional pain procedures
(This special issue belongs to the Section Anesthesiology)
Fibromyalgia: Diagnostic Progress and Therapeutic Advances submission deadline 17 Nov 2026 | 3 articles | Viewed by 3127 | Submission Open
Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS
(This special issue belongs to the Section Clinical Neurology)
Advancing the Clinical Management of Myeloproliferative Neoplasms (MPNs) submission deadline 18 Nov 2026 | 2 articles | Viewed by 1591 | Submission Open
Keywords: myeloproliferative neoplasms; targeted therapies; emerging therapies; outcomes; thrombosis; thrombosis prevention
(This special issue belongs to the Section Hematology)
Perioperative Care and Anaesthesia: Clinical Challenges and Future Perspectives
edited by
submission deadline 18 Nov 2026 | 4 articles | Viewed by 1501 | Submission Open
Keywords: perioperative hemodynamic monitoring; patient blood management; perioperative bleeding and coagulopathy; cardiac anesthesia and critical care; mechanical circulatory support; goal-directed therapy; viscoelastic testing; perioperative anemia; transfusion; iron deficiency; perioperative shock
(This special issue belongs to the Section Anesthesiology)
Pediatric Dentistry: Recent Advances, Current Issues and Future Challenges submission deadline 20 Nov 2026 | 9 articles | Viewed by 31067 | Submission Open
Keywords: pediatric dentistry; recent advances; current issues; future challenges; orthodontic issues; preventive strategies; access to care disparities; behavioral management; multidisciplinary collaboration; oral health
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 20 Nov 2026 | 5 articles | Viewed by 13269 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition
edited by Botond Csiky
submission deadline 20 Nov 2026 | 3 articles | Viewed by 12332 | Submission Open
Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease
(This special issue belongs to the Section Nephrology & Urology)
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