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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Spine Neurosurgery: Latest Advances and Prospects

edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee

submission deadline 20 Aug 2026 | Viewed by 52 | Submission Open

Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity

(This special issue belongs to the Section Clinical Neurology)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Aug 2026 | Viewed by 51 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

edited by

Maria-Arantzazu Ruescas-Nicolau

Marco Iosa

and

María Luz Sánchez-Sánchez

submission deadline 20 Aug 2026 | Viewed by 51 | Submission Open

Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment

(This special issue belongs to the Section Clinical Neurology)

Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations

edited by

Jorge Sánchez-Infante

submission deadline 20 Aug 2026 | Viewed by 49 | Submission Open

Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Orthopedic Infections: 2nd Edition

edited by

Hyonmin Choe

submission deadline 20 Aug 2026 | Viewed by 48 | Submission Open

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction

edited by

Rita Pavasini

submission deadline 20 Aug 2026 | Viewed by 45 | Submission Open

Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage

edited by Sylvia Bele

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment

(This special issue belongs to the Section Clinical Neurology)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management

edited by

Wojciech Gawȩcki

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic

(This special issue belongs to the Section Otolaryngology)

The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications

edited by

Anna Di Sessa

submission deadline 20 Aug 2026 | Viewed by 41 | Submission Open

Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Hypercholesterolemia

edited by Ana Catarina Alves

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC)

edited by

Ewa Małecka-Wojciesko

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR

(This special issue belongs to the Section Oncology)

Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease

edited by

Laura Ramos

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Clinical Perspectives on Chronic Kidney Disease

edited by Luca Visconti

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications

(This special issue belongs to the Section Nephrology & Urology)

Physiotherapy: Multidisciplinary Interventions and Digital Health

edited by

Esteban Obrero-Gaitán

and

Irene Cortés Pérez

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal; neurological; cognitive; pediatric; pulmonary; cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults

(This special issue belongs to the Section Clinical Rehabilitation)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Aug 2026 | Viewed by 39 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health

edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan

submission deadline 20 Aug 2026 | Viewed by 38 | Submission Open

Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’ s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Pharmacological Pain Management Advances

edited by Michael A. Ueberall

submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open

Keywords: pain management; drug therapy; analgesics; co-analgesics; drug safety and drug interactions; real-world evidence

(This special issue belongs to the Section Anesthesiology)

Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation

edited by Michele Finotti and Francesco D’Amico

submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open

Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes

edited by Kevin Liou

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI

(This special issue belongs to the Section Cardiology)

Clinics and Management of Allergic and Inflammatory Skin Disorders

edited by

Andrzej Jaworek

and

Marta Szepietowska

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management

(This special issue belongs to the Section Dermatology)

Anesthesia and Intensive Care: Clinical Practices and Prospects

edited by

Jungchan Park

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization

(This special issue belongs to the Section Intensive Care)

Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)

edited by

Alexander Hermann

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)

(This special issue belongs to the Section Intensive Care)

Updates on Neuromuscular Diseases

edited by

Menachem Sadeh

submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open

Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics

(This special issue belongs to the Section Clinical Neurology)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach

edited by

Paul Abraham

submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open

Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing

(This special issue belongs to the Section Cardiology)

Advances in Pulmonary Embolism Therapeutic

edited by

Jeisson Osorio

submission deadline 20 Aug 2026 | Viewed by 30 | Submission Open

Keywords: acute pulmonary embolism; chronic pulmonary embolism; chronic thromboembolic disease; chronic thromboem-bolic pulmonary hypertension; catheter-directed therapy; pulmonary endarterectomy; balloon pulmonary angio-plasty

(This special issue belongs to the Section Vascular Medicine)

Revisional and Conversion Bariatric Surgery: Safety and Outcomes

edited by Jerry Dang

submission deadline 20 Aug 2026 | Viewed by 29 | Submission Open

Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD

(This special issue belongs to the Section General Surgery)

Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction

edited by

Pasquale Palmiero

and Maria Maiello

submission deadline 20 Aug 2026 | Viewed by 29 | Submission Open

Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health

(This special issue belongs to the Section Cardiovascular Medicine)

Targeting Extravalvular Burden Associated with Valvular Heart Disease

edited by

Giovanni La Canna

submission deadline 20 Aug 2026 | Viewed by 27 | Submission Open

Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging

(This special issue belongs to the Section Cardiology)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Aug 2026 | Viewed by 22 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Future-Proof Care for Patients with Kidney Stones

edited by

Stijn Roemeling

and Oliver Wiseman

submission deadline 20 Aug 2026 | Viewed by 22 | Submission Open

Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life

(This special issue belongs to the Section Nephrology & Urology)

Managing Chronic Kidney Disease: Current Practices and Future Perspectives

edited by Maria L. Gonzalez-Suarez

submission deadline 20 Aug 2026 | Viewed by 21 | Submission Open

Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation

edited by Laura Scaramuzzo

submission deadline 20 Aug 2026 | Viewed by 18 | Submission Open

Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery

(This special issue belongs to the Section Orthopedics)

Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach

edited by

Giovanni Ricevuti

and

Salvatore Chirumbolo

submission deadline 20 Aug 2026 | Viewed by 15 | Submission Open

Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes

(This special issue belongs to the Section Clinical Rehabilitation)

New Perspectives and Innovations in Critical Illness

edited by

Francesco Alessandri

and

Giovanni Giordano

submission deadline 20 Aug 2026 | Viewed by 14 | Submission Open

Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support

(This special issue belongs to the Section Intensive Care)

Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life

edited by

Gloria Roberti

and

Manuele Michelessi

submission deadline 21 Aug 2026 | Viewed by 55 | Submission Open

Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision

(This special issue belongs to the Section Ophthalmology)

Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition

edited by

Cinzia Forleo

and

Maria Cristina Carella

submission deadline 24 Aug 2026 | Viewed by 47 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype– phenotype correlations; rare variant interpretation; arrhythmias

(This special issue belongs to the Section Cardiology)

Knee Arthroplasty: Recent Advances and Future Challenges

edited by Matteo Marullo

submission deadline 25 Aug 2026 | Viewed by 72 | Submission Open

Keywords: knee arthroplasty; implant design; robotic surgery; revision surgery; biomechanics; clinical outcomes; perioperative care; fast-track surgery; digital orthopedics; partial knee replacement

(This special issue belongs to the Section Orthopedics)

Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention

edited by

Dougho Park

Hyoung Seop Kim

and

Jong Hun Kim

submission deadline 25 Aug 2026 | Viewed by 71 | Submission Open

Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment

(This special issue belongs to the Section Clinical Neurology)

Motor Activity and Cognitive Development in Early Childhood: Clinical Implications

edited by

Michele Roccella

and

Daniela Smirni

submission deadline 25 Aug 2026 | Viewed by 47 | Submission Open

Keywords: motor activity; cognitive development; early childhood; neurodevelopmental disorders; autism spectrum disorder; attention-deficit/hyperactivity disorder; developmental coordination disorder; preterm birth

(This special issue belongs to the Section Clinical Neurology)

Hand Surgery in Practice: Current Evidence and Emerging Techniques

edited by Guy Rubin

submission deadline 25 Aug 2026 | Viewed by 46 | Submission Open

Keywords: trauma; mallet; burn; nerve; tendon

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Kidney Transplantation: From Donor Selection to Recipient Outcomes

edited by Basma Merhi and Reginald Gohh

submission deadline 25 Aug 2026 | Viewed by 45 | Submission Open

Keywords: kidney transplantation; end-stage renal disease (ESRD); living-donor kidney transplantation; deceased-donor kidney transplantation; organ shortage; dialysis waiting time; transplant candidate evaluation; immunosuppression

(This special issue belongs to the Section Nephrology & Urology)

Advances in Percutaneous Coronary Intervention: Techniques, Tools and Outcomes

edited by Takashi Ashikaga

submission deadline 25 Aug 2026 | Viewed by 40 | Submission Open

Keywords: percutaneous coronary intervention; orbital atherectomy; coronary artery calcification; intravascular ultrasound (IVUS); optical coherence tomography (OCT)

(This special issue belongs to the Section Cardiovascular Medicine)

Gastrointestinal Cancer: Outcomes and Therapeutic Management—2nd Edition

edited by Maximos Frountzas

submission deadline 25 Aug 2026 | Viewed by 38 | Submission Open

Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm

(This special issue belongs to the Section Oncology)

Etiology, Diagnosis, and Management of Upper Gastrointestinal Disorders: 2nd Edition

edited by

Hidekazu Suzuki

submission deadline 25 Aug 2026 | Viewed by 38 | Submission Open

Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; helicobacter; eosinophilic esophagitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Personalized Therapy and Clinical Outcome for Vasculitis

edited by

Giulia Cassone

submission deadline 25 Aug 2026 | Viewed by 35 | Submission Open

Keywords: immune-mediated systemic vasculitis; personalized therapy; treatment; outcome; biomarkers; risk factors; management; multidisciplinary care

(This special issue belongs to the Section Immunology & Rheumatology)

Displaying special issue 1451-1500 on page 30 of 31.

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