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Advances in Percutaneous Coronary Intervention: Techniques, Tools and Outcomes

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 25 August 2026 | Viewed by 307

Editor


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Guest Editor
Department of Cardiology, Japanese Red Cross Musashino Hospital, Tokyo, Japan
Interests: orbital atherectomy; rotational atherectomy; lithotripsy; excimer laser

Special Issue Information

Dear Colleagues,

Percutaneous coronary intervention (PCI) continues to evolve rapidly with the development of advanced techniques and devices aimed at improving procedural success and long-term clinical outcomes, particularly in complex coronary lesions. This Special Issue focuses on contemporary innovations in PCI, encompassing lesion preparation strategies, intravascular imaging guidance, atherectomy technologies, and adjunctive tools that optimize stent deployment and patient outcomes.

Among these advances, effective management of heavily calcified coronary artery disease remains a critical challenge in interventional cardiology. Atherectomy techniques, including orbital atherectomy (OA), have emerged as valuable tools for lesion modification, enabling safer and more effective PCI in complex anatomical settings. OA offers distinct mechanical and procedural advantages, particularly in eccentric calcification, challenging wire bias, ostial and tortuous lesions, and bifurcation disease, through its differential sanding mechanism and bidirectional operation.

This Special Issue welcomes original research articles and reviews addressing innovative PCI techniques, device optimization, procedural outcomes, and complication management. Contributions highlighting real-world experience, technical considerations, and outcome data across varied PCI applications are encouraged, with the aim of advancing clinical practice and improving patient care in contemporary interventional cardiology.

Prof. Dr. Takashi Ashikaga
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • percutaneous coronary intervention
  • orbital atherectomy
  • coronary artery calcification
  • intravascular ultrasound (IVUS)
  • optical coherence tomography (OCT)

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Published Papers (1 paper)

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Review

20 pages, 23027 KB  
Review
Tips and Tricks of Orbital Atherectomy in Real-World Clinical Practice
by Takashi Ashikaga, Toshihiro Nozato, Yasutoshi Nagata, Tetsumin Lee, Masakazu Kaneko, Toru Misawa, Masashi Nagase, Mao Matsuyama, Daigo Kachi, Maki Ohira and Kazuki Matsuda
J. Clin. Med. 2026, 15(13), 4913; https://doi.org/10.3390/jcm15134913 (registering DOI) - 24 Jun 2026
Abstract
Orbital atherectomy (OA) is a highly effective atherectomy device used to treat heavily calcified coronary arteries. The technique for using OA is critical and depends on appropriate use of the dedicated guidewire. OA employs a centrifugal, differential sanding mechanism with bidirectional movement. When [...] Read more.
Orbital atherectomy (OA) is a highly effective atherectomy device used to treat heavily calcified coronary arteries. The technique for using OA is critical and depends on appropriate use of the dedicated guidewire. OA employs a centrifugal, differential sanding mechanism with bidirectional movement. When used with proper technique, the device appears to be associated with a low rate of complications, such as bradycardia and slow flow, compared with rotational atherectomy (RA), and results in high procedural success rates. We describe our experience with the OA device and procedural techniques in our catheterization laboratory. Full article
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