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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition

edited by

Tomasz Rechciński

submission deadline 25 Jun 2026 | Viewed by 86 | Submission Open

Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure

(This special issue belongs to the Section Cardiology)

Oral Health and Systemic Diseases: Clinical Insights

edited by

Fabio Piras

submission deadline 25 Jun 2026 | Viewed by 71 | Submission Open

Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Surgical Innovations in Pediatric Orthopedics

edited by

Hoon Park

submission deadline 25 Jun 2026 | Viewed by 61 | Submission Open

Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing

(This special issue belongs to the Section Orthopedics)

Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives

edited by Shintaro Chiba

submission deadline 25 Jun 2026 | Viewed by 61 | Submission Open

Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology

(This special issue belongs to the Section Respiratory Medicine)

Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications

edited by

Etsuo Chihara

submission deadline 25 Jun 2026 | Viewed by 58 | Submission Open

Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Management of Corneal Diseases

edited by Nicola Cardascia

submission deadline 25 Jun 2026 | Viewed by 57 | Submission Open

Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation

(This special issue belongs to the Section Ophthalmology)

Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases

edited by

Nikolaos Pararas

submission deadline 25 Jun 2026 | Viewed by 54 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management of Traumatic Brain Injury

edited by Adam James Wells and Peter Hutchinson

submission deadline 25 Jun 2026 | Viewed by 52 | Submission Open

Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence

(This special issue belongs to the Section Clinical Neurology)

Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Jun 2026 | Viewed by 51 | Submission Open

Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Bariatric Surgery: Current Status and Emerging Clinical Trends

edited by Collin E. M. Brathwaite

submission deadline 25 Jun 2026 | Viewed by 51 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation

(This special issue belongs to the Section General Surgery)

Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes

edited by Vítor Duque

submission deadline 25 Jun 2026 | Viewed by 50 | Submission Open

Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research

(This special issue belongs to the Section Infectious Diseases)

Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 25 Jun 2026 | Viewed by 45 | Submission Open

Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in Immunohematology: From Pathophysiology to Tailored Treatments

edited by

Giorgio Costagliola

submission deadline 25 Jun 2026 | Viewed by 44 | Submission Open

Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination

(This special issue belongs to the Section Immunology & Rheumatology)

Cystic Fibrosis: Management Strategies and Patient Outcomes

edited by Marta Rachel

submission deadline 25 Jun 2026 | Viewed by 42 | Submission Open

Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management

(This special issue belongs to the Section Respiratory Medicine)

Integrating Artificial Intelligence and Contextual Factors in Emergency Care

edited by Ancor Sanz-García and

José Luis Martín-Conty

submission deadline 25 Jun 2026 | Viewed by 39 | Submission Open

Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics

(This special issue belongs to the Section Emergency Medicine)

Advances in General and Regional Anaesthesia

edited by Michał Jan Stasiowski,

Nikola Zmarzły

and

Beniamin Oskar Grabarek

submission deadline 26 Jun 2026 | Viewed by 67 | Submission Open

Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia

(This special issue belongs to the Section Anesthesiology)

Youth Sports Injuries: From Prevalence to Prevention

edited by Swarup Mukherjee and

Gregory C. Bogdanis

submission deadline 30 Jun 2026 | 4 articles | Viewed by 12430 | Submission Open

Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes

(This special issue belongs to the Section Sports Medicine)

The Atrial Fibrillation–Heart Failure Interconnection: Challenges and Innovations in Diagnosis and Treatment

edited by

Roberto De Ponti

and

Michele Golino

submission deadline 30 Jun 2026 | Viewed by 167 | Submission Open

Keywords: atrial fibrillation; catheter ablation; ventricular dysfunction; myocardial remodeling; diastolic dysfunction; biomarkers; anti-arrhythmia agents; risk assessment; artificial intelligence; telemedicine

(This special issue belongs to the Section Cardiovascular Medicine)

Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management

edited by

Janan Abbas

and

Deborah Alperovitch

submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open

Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics

(This special issue belongs to the Section Orthopedics)

Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management

edited by Joanna F. Blackburn

submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics

(This special issue belongs to the Section Dermatology)

New Clinical Insights into Acute Respiratory Failure

edited by

Christophe Guervilly

submission deadline 30 Jun 2026 | Viewed by 53 | Submission Open

Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony

(This special issue belongs to the Section Intensive Care)

Clinical Advances in Aortic Disease and Revascularization: 2nd Edition

edited by Andrej Udelnow

submission deadline 30 Jun 2026 | Viewed by 46 | Submission Open

Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound

(This special issue belongs to the Section Vascular Medicine)

Robotic-Assisted Hepato-Pancreato-Biliary (HPB) Surgery: Advances and Clinical Perspectives

edited by

Michele Tedeschi

and Riccardo Memeo

submission deadline 30 Jun 2026 | Submission Open

Keywords: liver surgery; pancreatic surgery; HPB surgery; robotic surgery; robotic systems; advances in HPB surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Anterior Cruciate Ligament Injury Treatment

edited by Goran Vrgoč

submission deadline 1 Jul 2026 | Viewed by 30 | Submission Open

Keywords: anterior cruciate ligament (ACL) injury; ACL reconstruction techniques; nonoperative ACL treatment; ACL graft; knee biomechanics; return-to-sport assessment; ACL rehabilitation; neuromuscular and proprioceptive training; athletic injuries; performance-enhancing substances; reinjury prevention; psychological readiness; ACL performance testing; osteoarthritis risk

(This special issue belongs to the Section Orthopedics)

Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation

edited by Katarzyna A. Majewska and Piotr Fichna

submission deadline 2 Jul 2026 | Viewed by 73 | Submission Open

Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Management for Coronary Artery Disease and Revascularization

edited by Mohammad Reza Movahed

submission deadline 10 Jul 2026 | 3 articles | Viewed by 4708 | Submission Open

Keywords: coronary artery disease; coronary syndrome; stenting; revascularization; cardiovascular

(This special issue belongs to the Section Cardiovascular Medicine)

Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics

edited by Dafni Charisopoulou and

Michael Henein

submission deadline 10 Jul 2026 | 1 articles | Viewed by 267 | Submission Open

Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure

(This special issue belongs to the Section Cardiology)

Gynecologic Cancers: Integrating Established Standards and Innovative Approaches

edited by Radu Vladareanu and Liviu Bilteanu

submission deadline 10 Jul 2026 | Viewed by 56 | Submission Open

Keywords: gynecological cancers; cervical cancer; ovarian cancer; endometrial cancer; vulvar and vaginal tumors; uterine sarcoma; fertility preservation; robotic surgery; image-guided radiotherapy (IGRT); brachytherapy; proton and FLASH radiotherapy; immunotherapy; radiomics; artificial intelligence; digital twin; multimodal treatment; survivorship and quality of life

(This special issue belongs to the Section Oncology)

Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside

edited by

Silvano Dragonieri

and

Andras Bikov

submission deadline 10 Jul 2026 | Viewed by 54 | Submission Open

Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers

(This special issue belongs to the Section Respiratory Medicine)

Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives

edited by Pier Alberto Testoni

submission deadline 10 Jul 2026 | Viewed by 52 | Submission Open

Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Open, Hybrid and Endovascular Repair of Visceral Artery Aneurysms: State of the Art and Clinical Perspectives

edited by

Andrea Xodo

, Francesco Squizzato and Vincenzo Vento

submission deadline 10 Jul 2026 | Viewed by 13 | Submission Open

Keywords: visceral artery aneurysms; endovascular treatment; open surgical repair; hybrid approach; covered stents; end-organ ischemia; long-term durability; patient selection

(This special issue belongs to the Section Vascular Medicine)

Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery

edited by

Cosmin Ioan Faur

, Rareș Calin Roman and Mihaela Carmen Hedeşiu

submission deadline 15 Jul 2026 | 1 articles | Viewed by 816 | Submission Open

Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jul 2026 | Viewed by 145 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Total Hip Arthroplasty Today: Trends, Challenges, and Future Directions

edited by

Seung-Jae Lim

submission deadline 15 Jul 2026 | Viewed by 98 | Submission Open

Keywords: complex hip arthroplasty; surgical technique; innovative implant; new technology; robotic surgery; navigation surgery; artificial intelligence; complications; periprosthetic joint infection; periprosthetic fracture; dislocation

(This special issue belongs to the Section Orthopedics)

Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | Viewed by 82 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery

edited by Shingo Tsujinaka

submission deadline 15 Jul 2026 | Viewed by 71 | Submission Open

Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes

(This special issue belongs to the Section General Surgery)

Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies

edited by

Luigi Carbone

submission deadline 15 Jul 2026 | Viewed by 63 | Submission Open

Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Jul 2026 | Viewed by 58 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

Neurosurgery Advancements: Techniques and Patient Outcomes

edited by Vianney Gilard

submission deadline 15 Jul 2026 | Viewed by 49 | Submission Open

Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes

(This special issue belongs to the Section Clinical Neurology)

Glaucoma: Advances in Diagnosis, Management, and Vision Preservation

edited by

Masaki Tanito

and

Takuhei Shoji

submission deadline 15 Jul 2026 | Viewed by 48 | Submission Open

Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT; micropulse; cyclophotocoagulation; etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function

(This special issue belongs to the Section Ophthalmology)

Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options

edited by Przemysław Puz,

Nikolaos Grigoriadis

and

Eduardo Agüera-Morales

submission deadline 15 Jul 2026 | Viewed by 47 | Submission Open

Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection

(This special issue belongs to the Section Clinical Neurology)

Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders

edited by

Ewelina Bak

and Sylwia Krzemińska

submission deadline 15 Jul 2026 | Viewed by 45 | Submission Open

Keywords: risk factors; secondary prevention; health education; health behaviors

(This special issue belongs to the Section Clinical Rehabilitation)

Understanding Dermatitis: Symptoms and Effective Treatment Options

edited by

Emi Sato

and Shinichi Imafuku

submission deadline 15 Jul 2026 | Viewed by 45 | Submission Open

Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data

(This special issue belongs to the Section Dermatology)

Novel Therapeutic Strategies in Rheumatoid Arthritis

edited by Mislav Radić

submission deadline 15 Jul 2026 | Viewed by 41 | Submission Open

Keywords: rheumatoid arthritis; targeted therapies; biological agents; small molecule inhibitors; biomarkers; personalized medicine; treatment response

(This special issue belongs to the Section Immunology & Rheumatology)

Cardiac Arrhythmias: Current Status and Future Directions

edited by

Jackson J. Liang

submission deadline 20 Jul 2026 | 1 articles | Viewed by 6387 | Submission Open

Keywords: ventricular tachycardia; atrial fibrillation; catheter ablation; novel therapies; complex arrhythmias

(This special issue belongs to the Section Cardiology)

Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation

edited by

Rahul Vaidya

submission deadline 20 Jul 2026 | 1 articles | Viewed by 704 | Submission Open

Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures

(This special issue belongs to the Section Orthopedics)

Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives

edited by

Do-youn Lee

and

Myoung-Kwon Kim

submission deadline 20 Jul 2026 | 1 articles | Viewed by 616 | Submission Open

Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine

(This special issue belongs to the Section Clinical Rehabilitation)

Integrating Artificial Intelligence into Plastic, Reconstructive, and Aesthetic Surgery: Innovations, Challenges, and Clinical Application

edited by

Roberto Cuomo

and

Gianluca Marcaccini

submission deadline 20 Jul 2026 | 1 articles | Viewed by 364 | Submission Open

Keywords: plastic; reconstructive; aesthetic surgery; artificial intelligence; AI in plastic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management

edited by

Valerio Pisani

submission deadline 20 Jul 2026 | 1 articles | Viewed by 338 | Submission Open

Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury

(This special issue belongs to the Section Clinical Rehabilitation)

Minimally Invasive Spine Surgery: Evidence, Advances and Controversies

edited by

Miltiadis Georgiopoulos

, Constantine Constantoyannis,

Mark A. MacLean

and Oliver Lasry

submission deadline 20 Jul 2026 | Viewed by 240 | Submission Open

Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality

(This special issue belongs to the Section Clinical Neurology)

Displaying special issue 1351-1400 on page 28 of 32.

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