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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Latest Review Papers in Molecular Genetics and Genomics 2024

edited by

Apostolos Zaravinos

submission deadline 20 Jul 2025 | Viewed by 807 | Submission Open

Keywords: gene regulation; chromatin; epigenetics; genomes; cancer genetics and epigenetics; functional genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into the Obstetrics and Gynecology

edited by

Gaspare Cucinella

submission deadline 20 Jul 2025 | Viewed by 784 | Submission Open

Keywords: ginecology; pelvic disorders; endometrial; cervical and ovarian cancers; covid and pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research of Gut Microbiota in Human Health and Diseases

edited by

Juan Francisco Martínez-Blanch

submission deadline 20 Jul 2025 | Viewed by 781 | Submission Open

Keywords: gut microbiota; gut metabolites; gastroenterology; microbiology; inflammation; human diseases

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Cellular Mechanisms of Skin Diseases (Second Edition)

edited by

Elisabetta Palazzo

submission deadline 20 Jul 2025 | 2 articles | Viewed by 767 | Submission Open

Keywords: hyperproliferative skin diseases; psoriasis; keratinocyte carcinoma; actinic keratosis; atopic dermatitis; skin inflammation; inflammation-associated skin diseases; epidermal differentiation; epidermal cell metabolism; 3D models; in vivo models

(This special issue belongs to the Section Molecular Biology)

Advances in Bioactive Nanoparticles and Cancer: From Biomarker Discovery to Drug Delivery

edited by Paola Gagni

submission deadline 20 Jul 2025 | 1 articles | Viewed by 741 | Submission Open

Keywords: nanoparticles; extracellular particles; extracellular vesicles; nanocarriers; drug delivery; biosensing; biomarker discovery; nanomedicine; liquid biopsy; advanced diagnostics; cancer

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms of Bone Injury and Bone Tissue Regeneration

edited by Nasim Golafshan

submission deadline 20 Jul 2025 | 1 articles | Viewed by 733 | Submission Open

Keywords: bone formation; osteoblast diffrentiation; cell-based materials

(This special issue belongs to the Section Materials Science)

Synthesis and Characterization of Nanocarriers and Hydrogels for Multiple Biomedical Applications

edited by

Tilahun Ayane Debele

submission deadline 20 Jul 2025 | Viewed by 701 | Submission Open

Keywords: nanocarrier synthesis; nanocarrier characterization; stimulus-sensitive nanocarriers; hydrogels; drug delivery systems; biomedical applications; nanotechnology in medicine; targeted drug delivery; controlled release; theranostic; nanomedicine; pH-sensitive nanocarriers; temperature-sensitive hydrogels; polymer-based nanocarriers; nanoparticle-hydrogel composites

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research in Myocarditis

edited by Cristina Vicenzetto

submission deadline 20 Jul 2025 | 1 articles | Viewed by 698 | Submission Open

Keywords: myocarditis; autoimmunity; viral myocarditis; molecular mechanisms; genetic background; therapeutic targets

(This special issue belongs to the Section Molecular Immunology)

Stroke: Novel Molecular Mechanisms and Therapeutic Approaches

edited by Kang-Ho Choi

submission deadline 20 Jul 2025 | Viewed by 681 | Submission Open

Keywords: stroke; cerebrovascular disease; mechanisms; treatment; diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Modulating the Function of the Immune System by Thyrotropin and Thyroid Hormones

edited by Graciela Alicia Cremaschi and Claudia Gabriela Pellizas

submission deadline 20 Jul 2025 | Viewed by 675 | Submission Open

Keywords: thyrotropin (TSH); thyroid hormones (THs); immune modulation; immunology; immune; autoimmune; immunoendocrinology; hypothalamic-pituitary-thyroid axis; antitumor immune response

(This special issue belongs to the Section Molecular Immunology)

KRAS-Mutant Cancers: From Basic Biology to Clinical Translation

edited by

Mirela Sedic

Sérgia Velho

and Luka Bočkor

submission deadline 20 Jul 2025 | Viewed by 663 | Submission Open

Keywords: KRAS mutations; KRAS signalling; cancer; KRAS inhibitors; drug resistance; tumour microenvironment; cellular metabolism

(This special issue belongs to the Section Molecular Oncology)

Iron and Sulfur in Plants, 4th Edition

edited by

Stefania Astolfi

and

Silvia Celletti

submission deadline 20 Jul 2025 | Viewed by 602 | Submission Open

Keywords: biofortification; Fe– S clusters; iron; iron deficiency; metabolites; methionine; nutrient interaction; root exudates; strategy I; strategy ii; sulfur; sulfur deficiency

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Genetic Research on Psychiatric Disorders

edited by Lawrence Shih-Hsin Wu

submission deadline 20 Jul 2025 | Viewed by 593 | Submission Open

Keywords: genetics; bipolar disorder; schizophrenia; major depressive disorder; autism; substance abuse; genomics

(This special issue belongs to the Section Molecular Neurobiology)

GABA Signaling in Health and Disease in the Nervous System, 2nd Edition

edited by

Alexandre Hiroaki Kihara

submission deadline 20 Jul 2025 | Viewed by 592 | Submission Open

Keywords: gamma-aminobutyric acid; neurodevelopment; neuronal differentiation; neuronal disorders; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Colorectal Cancer: Molecular Mechanism and Treatment Strategies

edited by

Pina Ziranu

submission deadline 20 Jul 2025 | Viewed by 548 | Submission Open

Keywords: colorectal cancer; personalized treatment; treatment strategies; cancer biology

(This special issue belongs to the Section Molecular Oncology)

Rational Design and Synthesis of Bioactive Molecules, 2nd Edition

edited by

Irena Kostova

submission deadline 20 Jul 2025 | Viewed by 546 | Submission Open

Keywords: synthesis; structure; bonding; reactivity; chemical properties; physical properties; pharmacological activity; structure– activity relationship; applications

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Hereditary Spherocytosis

edited by

Susana Rocha

and

Alice Santos-Silva

submission deadline 20 Jul 2025 | Viewed by 541 | Submission Open

Keywords: hereditary spherocytosis; erythrocyte membrane molecular defects; next-generation sequencing; molecular diagnosis; molecular mechanisms of disease

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular and Cellular Mechanisms of Genotoxicity

edited by

Bernd Kaina

submission deadline 20 Jul 2025 | Viewed by 538 | Submission Open

Keywords: DNA damage; gene instab; genetic instab; DNA methyl; genotoxic; gene mutation; DNA repair; genotoxicity; toxicogenetic; toxicogenomic

(This special issue belongs to the Section Molecular Toxicology)

Molecular Mechanisms and Therapeutic Strategies to Overcome Drug Resistance in Cancer

edited by

Inamul Haque

submission deadline 20 Jul 2025 | Viewed by 530 | Submission Open

Keywords: drug resistance; cancer therapy; targeted therapy; nanotechnology; tumor microenvironment; signaling pathway; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Vitamin D Signaling in Human Health and Diseases

edited by

Daniela Rovito

submission deadline 20 Jul 2025 | Viewed by 529 | Submission Open

Keywords: vitamin D receptor; vitamin D; prevention; therapeutic potential; mineral homeostasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanistic Studies of Mitosis

edited by Eleni Petsalaki

submission deadline 20 Jul 2025 | Viewed by 524 | Submission Open

Keywords: mitosis; cancer; cell biology; spindle checkpoint; abscission; abscission checkpoint; cytokinesis

(This special issue belongs to the Section Biochemistry)

Omics-Driven Unveiling of the Structure and Function of Nanoparticles

edited by

Elva Morretta

submission deadline 20 Jul 2025 | Viewed by 511 | Submission Open

Keywords: nanoparticles; nanotechnology; drug delivery; protein corona; proteomics; nano-proteomics; matabolomics; lipidomics

(This special issue belongs to the Section Molecular Biophysics)

Advancements in Genomic Technologies for Molecular Safety Assessment

edited by

Eric Blomme

submission deadline 20 Jul 2025 | Viewed by 501 | Submission Open

Keywords: gene expression; safety assessment; genomic technologies; genomic tools; molecular toxicology; toxicity; predictive safety assessments; proteomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Molecular Pathology, Drug Resistance and Diagnostics of Human Fungal Diseases

edited by

Chi-Ching Tsang

submission deadline 20 Jul 2025 | Viewed by 496 | Submission Open

Keywords: host-fungal interaction; pathogenesis; virulence; antifungal immunity; antifungal resistance; molecular diagnosis

(This special issue belongs to the Section Molecular Microbiology)

Superoxide

edited by

Francesco Caruso

and

Miriam Rossi

submission deadline 20 Jul 2025 | Viewed by 496 | Submission Open

Keywords: superoxide; SOD; antioxidants; superoxide radical; natural product

(This special issue belongs to the Section Biochemistry)

Molecular Metabolism in Plant Chemistry

edited by

Diamanto Lazari

submission deadline 20 Jul 2025 | Viewed by 475 | Submission Open

Keywords: phytochemistry; plant secondary metabolism; biosynthesis of secondary metabolites; plant and pathogens; stress tolerance and resistance; plant cell cultures; plant biotechnology; bioactive natural products

(This special issue belongs to the Section Biochemistry)

Optical Molecular Systems: From Design to Applications

edited by

Amador Menéndez-Velázquez

submission deadline 20 Jul 2025 | Viewed by 474 | Submission Open

Keywords: luminescent materials; spectral conversion; smart optical materials; human-centric lighting; healthcare diagnostics; imaging; and therapeutics; advanced optical sensors

(This special issue belongs to the Section Materials Science)

Molecular and Cellular Mechanisms in Learning and Memory

edited by

Giovanna Traina

submission deadline 20 Jul 2025 | Viewed by 473 | Submission Open

Keywords: learning; memory; animal models; conditioning; molecular mechanisms; genetic mechanisms; epigenetic mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Studies of Age-Related Diseases: Immunosenescence and Inflammaging

edited by

Lia Ginaldi

submission deadline 20 Jul 2025 | Viewed by 468 | Submission Open

Keywords: aging; age-related; immunosenescence; immune system; inflammaging

(This special issue belongs to the Section Molecular Immunology)

Molecular Applications of Spectroscopy in Drug Structure and Activity Analysis

edited by

Malvina Orkoula

submission deadline 20 Jul 2025 | Viewed by 465 | Submission Open

Keywords: spectroscopic techniques; Raman microscopy and imaging; IR/FT-IR/ATR; UV/Vis; XRD; polymorphic forms; material purity; pharmaceutical finished products; biosimilars; stability of APIs and excipients; interaction between APIs and excipients; counterfeit identification; reverse engineering in pharmacy; at-line; in-line

(This special issue belongs to the Section Molecular Biophysics)

Editorial Board Member's Collection Series: The Memory of the Immune Cells

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Jul 2025 | 1 articles | Viewed by 446 | Submission Open

Keywords: immunological memory; innate immune memory; dendritic cells; natural killer cells; macrophage memory

(This special issue belongs to the Section Molecular Immunology)

Role of the Epithelial Mesenchymal Transition in Cancer Development and Invasiveness

edited by

Elisabetta Aldieri

submission deadline 20 Jul 2025 | Viewed by 445 | Submission Open

Keywords: epithelial mesenchymal transition; EMT; cancer; epithelial protein; mesenchymal phenotype; therapeutic approach

(This special issue belongs to the Section Molecular Oncology)

Myelination in the Nervous Systems: From Molecular Pathways to Therapeutic Strategies

edited by Yanming Wang

submission deadline 20 Jul 2025 | Viewed by 438 | Submission Open

Keywords: myelination; the central nervsou system; neurodegenerative discorders; multiple sclerosis; leukodystrophies; myelin repair and regeneration

(This special issue belongs to the Section Molecular Biology)

The Molecular Mechanisms and Pathogenesis of Food Allergy and New Technologies

edited by

Mónica Carrera

submission deadline 20 Jul 2025 | Viewed by 434 | Submission Open

Keywords: food allergy; omics; genomics; proteomics; transcriptomics; metabolomics; systems biology; micro/nanoabrication

(This special issue belongs to the Section Molecular Immunology)

Molecular Linkages Between Obesity, Diabetes and Cancer

edited by Pilar F. Valerón

submission deadline 20 Jul 2025 | Viewed by 430 | Submission Open

Keywords: obesity; GLUT4; PPARg; lipid transporters (CD36 and AQP7); cancer progression; metastasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chronic Lymphocytic Leukemia: Molecular Pathologies and Therapeutic Strategies

edited by Tang Her Jaing

submission deadline 20 Jul 2025 | Viewed by 423 | Submission Open

Keywords: chronic lymphocytic leukemia; genomic landscapes; precision medicine; clinical trials; biomarker

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chemoinformatics and Bioinformatics Tools in Structure-Activity Modelling in Molecular Sciences: 3rd Edition

edited by

Bono Lučić

submission deadline 20 Jul 2025 | Viewed by 423 | Submission Open

Keywords: chemoinformatics tools and models; bioinformatics tools and models; structure– activity modeling; structure– property modeling; QSAR; QSPR; drug/structure identification in bioprospecting research; molecular docking; molecular interactions; protein– protein interactions; development of algorithms; databases and web servers; data mining in chemoinformatics and bioinformatics; structure representation and optimization; molecular descriptors; modeling of health and environmentally relevant endpoints (activities; properties); toxicity modeling and prediction; carcinogenicity modeling and prediction; computational methods in molecular sciences; model validation approaches; multivariate modeling; predictive modeling; descriptive modeling; continuous data modeling; classification data modeling; machine learning in molecular sciences; deep learning in molecular sciences; structure visualization tools

(This special issue belongs to the Section Molecular Informatics)

New Advances in Cancer Stem Cell Research: 2nd Edition

edited by

Tomoyasu Sugiyama

submission deadline 20 Jul 2025 | Viewed by 411 | Submission Open

Keywords: cancer stem cell; biomarker; signaling; cancer-associated fibroblast; artificial intelligence; cell therapy; antibody therapy; cell therapy; gene expression

(This special issue belongs to the Section Molecular Oncology)

Molecular Precision Medicine: Unraveling Disease Mechanisms, Targeted Therapeutics and Innovative Diagnostics

edited by

Shairaz Baksh

submission deadline 20 Jul 2025 | Viewed by 403 | Submission Open

Keywords: molecular precision medicine; mass spectrometry; biomarkers; cancer; inflammation; neuroinflammation; neurodegenerative; diabetes; cardiometabolic disorders; mental health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

From Bench to Bedside: A Triad of Innovation in Gastric Cancer Treatment—Immunotherapies, Gene Therapy and Surgery Unite

edited by

Gregory Christodoulidis

submission deadline 20 Jul 2025 | Viewed by 402 | Submission Open

Keywords: immunotherapy; gene therapy; advanced surgery

(This special issue belongs to the Section Molecular Oncology)

Reproductive Toxicity of Chemicals

edited by

Maria Laura Zenclussen

submission deadline 20 Jul 2025 | Viewed by 392 | Submission Open

Keywords: reproductive health; fertility; anthropogenic chemicals; impaired fertility; reproductive toxicity; embryo; toxicants; hormone disruption; chemical exposure

(This special issue belongs to the Section Molecular Toxicology)

Molecular Research on Pathophysiology of Multiple Sclerosis and Neuroinflammation

edited by

Fabrizio Michetti

submission deadline 20 Jul 2025 | Viewed by 374 | Submission Open

Keywords: multiple sclerosis (MS); autoimmune diseases; encephalomyelitis; neuroinflammation; central nervous system (CNS); autoimmunity and neurodegeneration; molecular basis of immune mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research and Insight in Neurotransmission and Neuromodulation

edited by Miklos Jaszberenyi

submission deadline 20 Jul 2025 | Viewed by 357 | Submission Open

Keywords: histology; microanatomy; morphology; molecular biology; neurotransmitter; neuromodulator; neuropeptide; neurohormone; nervous system

(This special issue belongs to the Section Molecular Neurobiology)

Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes

edited by

Eugenio Luigi Iorio

submission deadline 20 Jul 2025 | Viewed by 356 | Submission Open

Keywords: redox systems; aging and disease; nutraceuticals; probiotics; animals; plants; aquatic ecosystems; microbiomes

(This special issue belongs to the Section Molecular Biology)

Hormone Metabolism and Signaling in Human Health and Disease

edited by

Kuo-Hu Chen

submission deadline 20 Jul 2025 | Viewed by 351 | Submission Open

Keywords: hormone metabolism; signaling pathways; pathophysiology; molecular and cellular biology; diseases originating from hormone disorders; hormonal therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Research on Bioinformatics Analysis of the Gut Microbiome and Transcriptome

edited by

Chenkai Ma

submission deadline 20 Jul 2025 | Viewed by 351 | Submission Open

Keywords: gut health; gut microbiome; transcriptome; multi-omics; bioinformatics; bowel cancer; gut infections; inflammatory bowel diseases

(This special issue belongs to the Section Molecular Informatics)

Endocannabinoids, Cannabinoids and Psychiatry: Biological Mechanisms—3rd Edition

edited by

Aron Weller

and Nicholas V. DiPatrizio

submission deadline 20 Jul 2025 | Viewed by 349 | Submission Open

Keywords: endocannabinoids; cannabinoids; psychiatry; neural mechanisms; molecular mechanisms; epigenetics; imaging; psychopathology; stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanomaterials for Biomedical and Environmental Applications

edited by

Łukasz Laskowski

submission deadline 20 Jul 2025 | Viewed by 348 | Submission Open

Keywords: nanomaterials; functional materials; biomaterials; nanocomposites; biocidal materials; environmental protection; nanostructured materials; mesoporous materials

(This special issue belongs to the Section Molecular Nanoscience)

Cutting-Edge Advances in Natural Bioactive Compounds

edited by

Luisa M. P. F. Amaral

and

Romeu A. Videira

submission deadline 20 Jul 2025 | Viewed by 347 | Submission Open

Keywords: natural bioactive compounds; discovery and isolation; chemical characterization; biological activities; mechanisms of action; pharmaceuticals; nutraceuticals; agricultural applications; cosmetic innovations

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Protease and Carbonic Anhydrase Inhibitors: 3rd Edition

edited by

Alessio Nocentini

submission deadline 20 Jul 2025 | Viewed by 341 | Submission Open

Keywords: carbonic anhydrase; protease; inhibitor; antiviral drug; antitumor drug; drug design; serine protease; metalloprotease; aspartic protease

(This special issue belongs to the Section Biochemistry)

Displaying special issue 401-450 on page 9 of 68.

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