Molecular Research on Tumor Suppressor Proteins
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 July 2025 | Viewed by 839
Special Issue Editor
Special Issue Information
Dear Colleagues,
DNA repair pathways are crucial for maintaining genome integrity and preventing tumorigenesis. Defective DNA repair factors can result in DNA abnormalities and irregular cell growth. Tumor suppressors such as BRCA1/BRCA2, PALB2, and RAD51C play essential roles in homologous recombination, a high-fidelity DNA repair pathway. This Special Issue aims to showcase recent research advances in the molecular mechanisms of tumor suppressor proteins in DNA repair pathways.
In this Special Issue of the International Journal of Molecular Sciences, we are calling for original research articles, reviews, and perspectives focusing on the molecular mechanisms underlying the essential functions of tumor suppressor proteins involved in DNA repair pathways. We are particularly interested in cellular, biochemical, and structural investigations of these DNA repair proteins, as well as contributions that focus on innovative research facilitating drug discovery and patient treatments.
We are seeking a diverse collection of high-quality original articles with in-depth analysis for this Special Issue. The focus is on enhancing our understanding of the intricate molecular strategies employed by DNA repair-related tumor suppressors to prevent genome abnormality and tumor formation. Your contributions to this Special Issue are welcome.
Dr. Jie Liu
Guest Editor
Manuscript Submission Information
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Keywords
- DNA repair
- genome stability
- tumor suppressor
- BRCA1
- BRCA2
- PALB2
- RAD51C
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