Advances in the Molecular Diagnosis and Treatment of Neurodegenerative Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 606
Special Issue Editor
2. CIBB—Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal
Interests: proteomics; translational biomarkers; neurodegenerative disorders
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases comprise a diverse group of disorders characterized by progressive neuronal dysfunction and loss, affecting both the central and peripheral nervous systems. These conditions, including Alzheimer's disease and Parkinson's disease (PD), represent a major global health burden, particularly as life expectancy increases. Despite extensive research, the molecular mechanisms underlying neurodegeneration remain incompletely understood, and effective therapeutic options are still lacking. Advances in molecular diagnostics, such as biomarker identification, imaging techniques, and omics-based approaches, are improving early disease detection and classification. Simultaneously, targeted molecular therapies, including gene and cell-based treatments, are emerging as promising strategies to modify disease progression.
This Special Issue will explore recent advances in molecular diagnostics and therapeutic interventions in neurodegenerative diseases. We welcome contributions focusing on novel biomarkers, cutting-edge diagnostic technologies, and innovative treatment strategies designed to delay, halt, or reverse neurodegeneration. A major focus will be placed on pre-clinical and clinical manuscripts that provide translational insights into disease mechanisms, diagnostic tools, and potential therapeutic approaches.
Dr. Bruno Manadas
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- neurodegenerative disorders
- biomarkers
- treatment
- omics
- systems biology
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