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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Nanomaterials: Approaches, Strategies and Applications

edited by

Andrea Bernardos

submission deadline 20 Dec 2025 | Viewed by 188 | Submission Open

Keywords: nanotechnology; biocides; antimicrobials; controlled release; drug delivery; antimicrobial agents; antimicrobial resistance; infection; nanoparticles

(This special issue belongs to the Section Materials Science)

Physiology and Pathophysiology of Neurodegeneration: New Insights and Advances from Molecular to Cellular Level

edited by

Alessandro Romano

and

Amilcare Barca

submission deadline 20 Dec 2025 | Viewed by 163 | Submission Open

Keywords: central and peripheral nervous systems; neuron homeostasis; neurodegeneration; neurodegenerative disease; neurophysiology; -omic technologies; induced pluripotent stem cell (iPSC); three-dimensional cell culture; organ-on-a-chip (OoC)

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Targets and Mechanisms of Innovative Therapies and Natural Adjuvants in Glioblastoma Management

edited by

Maria Grazia Bottone

submission deadline 20 Dec 2025 | Viewed by 140 | Submission Open

Keywords: glioblastoma; targeted therapy; traditional and emerging therapies; signaling pathways; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Redox Physiology

edited by Mateusz Mołoń

submission deadline 21 Dec 2025 | Viewed by 236 | Submission Open

Keywords: redox physiology; reactive oxygen species (ROS); reactive nitrogen species (RNS); oxidative stress; oxidation; redox signaling

(This special issue belongs to the Section Molecular Biology)

Molecular and Genetic Advances in Plant Breeding

edited by Francesca Taranto

submission deadline 25 Dec 2025 | Viewed by 62 | Submission Open

Keywords: genetic diversity; next-generation sequencing; marker-assisted selection; GWAS/QTL mapping; KASP genotyping; molecular biology TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Plant Sciences)

Skin Cancer: From Molecular Pathophysiology to Novel Treatment

edited by Soon-Hyo Kwon

submission deadline 25 Dec 2025 | Viewed by 44 | Submission Open

Keywords: basal cell carcinoma; malignant melanoma; molecular genetics; epigenetics; signaling pathways; tumor microenvironment; tumor resistance; biomarkers; molecular target; multiomics; genomics; transcriptomics; proteomics; metabolomics; skin cancer; squamous cell carcinoma

(This special issue belongs to the Section Molecular Oncology)

Molecular Endocrine Regulation in Health and Diseases

edited by Fady Hannah-Shmouni

submission deadline 25 Dec 2025 | Viewed by 22 | Submission Open

Keywords: exposome and endocrine disruptors; endocrine-disrupting chemicals (EDCs); environmental toxicology and hormonal health; epigenetics and endocrine function; endocrine regulation and chronic disease; public health and exposure mitigation; endocrine disruptors in the home and community

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Epigenetic Regulation and Molecular Mechanisms in Cardiovascular Diseases

edited by

Paschalis Karakasis

submission deadline 25 Dec 2025 | Viewed by 5 | Submission Open

Keywords: epigenetic regulation; cardiovascular disease; DNA methylation; histone modifications; non-coding RNAs; vascular inflammation; myocardial remodeling; molecular mechanisms; thera-peutic targets

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Pathogenesis and Therapies for Retinal and Optic Nerve Diseases

edited by

Toshiyuki Oshitari

submission deadline 30 Dec 2025 | 1 articles | Viewed by 3149 | Submission Open

Keywords: neurovascular unit; neurovascular cell death; neuroprotection; vasoprotection; regeneration; molecular and cellular pathologies; current and future therapies; drug delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Basis for Sustainable Management of Migratory Insects

edited by

Xingfu Jiang

submission deadline 30 Dec 2025 | Viewed by 121 | Submission Open

Keywords: migrant insects; molecular basis of population growth; migration and reproduction; migration and immunity; migration and diapause; migration and orientation; molecular regulation of migration

(This special issue belongs to the Section Molecular Biology)

Brain Ischemia: From Molecular Mechanisms to Innovative Therapies

edited by

Ryszard Pluta

submission deadline 30 Dec 2025 | Viewed by 116 | Submission Open

Keywords: ischemic neurodegeneration; focal brain ischemia; global brain ischemia; perinatal asphyxia; ischemic stroke; traumatic brain injury; apnea; neuroinflammation; proteins; genes; genes involved in neurodegeneration; glia-to-neurons genetic conversion; dementia; Alzheimer’s disease; genetic conversion of ischemia to Alzheimer's disease; new therapeutic approaches; biomarkers

(This special issue belongs to the Section Molecular Biology)

Quantifying Pesticide Molecular Properties Through Molecular Modeling Methods

edited by

Jean-Yves Le Questel

submission deadline 30 Dec 2025 | Viewed by 108 | Submission Open

Keywords: pesticide; three-dimensional structure; molecular docking; molecular dynamics; quantum mechanics; homology modeling; pesticide– target interactions; toxicity

(This special issue belongs to the Section Molecular Biophysics)

Role of Immune and Inflammatory Cells in Pulmonary Fibrosis

edited by Remo C. Russo

submission deadline 30 Dec 2025 | Viewed by 38 | Submission Open

Keywords: idiopathic pulmonary fibrosis (IPF); pulmonary immunology; precision medicine; single-cell RNA sequencing (scRNA-seq); spatial transcriptomics sequencing; animal model of pulmonary fibrosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovative Immune-Modulating Therapies and Cutting-Edge Technologies for Immune-Related Diseases

edited by

Xingxing Fan

submission deadline 30 Dec 2025 | Viewed by 17 | Submission Open

Keywords: immune heomostasis; immune related diseases; small molecules; cell therapy; bacteria and virus; antibodies

(This special issue belongs to the Section Molecular Immunology)

Evolutionary Drivers and Adaptive Mechanisms in Algal Organellar Genomes

edited by

Feng Liu

submission deadline 30 Dec 2025 | Viewed by 15 | Submission Open

Keywords: organellar genome of algae; molecular evolution; secondary structure of intron; evolutionary driving force; horizontal gene transfer

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Strategies in Cancer Therapy

edited by

Paolo Coghi

and

Carmine Coluccini

submission deadline 30 Dec 2025 | Viewed by 15 | Submission Open

Keywords: tumor microenvironment; small molecules; IDO1 inhibition; checkpoint inhibitor therapy; adoptive T cell therapy; metabolic reprogram; resistance mechanisms; immune modulation; immune reconstitution; combination therapy; immunosuppression

(This special issue belongs to the Section Molecular Oncology)

Editorial Board Members’ Collection Series: Cancer Metastasis

edited by

Carlos Cabañas

and

Sung-Hoon Kim

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7770 | Submission Open

Keywords: biomarkers; liquid biopsy; premetastatic niche; angiogenesis; immune evasion and suppression; genetic and epigenetic determinants; chemoresistance; extracellular vesicles

(This special issue belongs to the Section Molecular Oncology)

The Impact of Natural Bioactive Compounds on Human Health and Disease

edited by

Yeong-geun Lee

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4350 | Submission Open

Keywords: natural product chemistry; nuclear magnetic resonance; structural elucidation; herbal drug

(This special issue belongs to the Section Molecular Pharmacology)

Research Progress of Metabolomics in Health and Disease

edited by

Maria Assunta Acquavia

submission deadline 31 Dec 2025 | 5 articles | Viewed by 3905 | Submission Open

Keywords: metabolomics; health; diseases; target metabolites; mass spectrometry; hyphenated techniques

(This special issue belongs to the Section Molecular Biology)

Targeted Delivery of Nucleic Acids

edited by Yong-Serk Park

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3565 | Submission Open

Keywords: nucleic acid delivery; gene delivery; pDNA delivery; siRNA delivery; miRNA delivery; mRNA delivery; CRISPR-Cas delivery; nanoparticle; lipid nanoparticle; targeted therapy

(This special issue belongs to the Section Molecular Biology)

Recent Progress in Metabolic Diseases

edited by

Dariusz Chlubek

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1788 | Submission Open

Keywords: metabolic diseases; enzymes related to metabolic disorders; inborn errors of metabolism; inherited single-gene anomalies; molecular diagnostics in metabolic disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancements in Diagnostic and Preventive Pharmacogenomics

edited by Alireza Tafazoli

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1540 | Submission Open

Keywords: genome profiling; pharmacogenetic analysis; diagnostic pharmacogenomics; pre-emptive pharmacogenomics; advanced genotyping technologies

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Forensic Molecular Biology and Genetics

edited by

Anna Barbaro

submission deadline 31 Dec 2025 | Viewed by 907 | Submission Open

Keywords: nuclear and mt-DNA; rapid DNA analysis; next-generation sequencing; mRNA analysis; microbiome analysis; barcode DNA; time since deposition; fluid identification; DNA phenotyping; DNA ancestry

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into RNA Diseases

edited by

Naoyuki Kataoka

submission deadline 31 Dec 2025 | 1 articles | Viewed by 667 | Submission Open

Keywords: RNA splicing; RNA modification; RNA processing; translation; RNA transport

(This special issue belongs to the Section Molecular Genetics and Genomics)

Emerging Trends in Enzymology

edited by

Francesco Malatesta

submission deadline 31 Dec 2025 | Viewed by 549 | Submission Open

(This special issue belongs to the Section Biochemistry)

Molecular Entomology of Insects of Economic Importance: Advanced Molecular Approaches for Insect Pest Management

edited by

T. G. Emyr Davies

submission deadline 31 Dec 2025 | Viewed by 333 | Submission Open

Keywords: molecular entomology; insect pests; agricultural pests; disease vectors; beneficial insects; CRISPR; RNA interference; genome-wide approaches; computational biology; nanotechnology

(This special issue belongs to the Section Molecular Biology)

Chelating Ligands in Therapeutics: Recent Advances and Future Directions

edited by

Matteo Mori

and

Fiorella Meneghetti

submission deadline 31 Dec 2025 | Viewed by 305 | Submission Open

Keywords: metal complexes; chelation therapy; chelating agents; diagnostic imaging; metal detoxification; chelation pharmacokinetics

(This special issue belongs to the Section Biochemistry)

Selected Papers from the 5th International Symposium on Frontiers in Molecular Science (ISFMS)

edited by

Yoshinori Marunaka

and

Masayuki Takahashi

submission deadline 31 Dec 2025 | Viewed by 304 | Submission Open

Keywords: protein structure and function; multidomain proteins; drug design and drug resistance; enzymes; molecular biology of galectins; glycobiophysics; NMR spectroscopy; specific sensory systems; brain and systemic function

(This special issue belongs to the Section Biochemistry)

Functional Microbiomes and the Organization of Marine Communities: Molecular Biological Insights

edited by

Daniel Rittschof

submission deadline 31 Dec 2025 | Viewed by 203 | Submission Open

Keywords: marine communities; functional microbiomes; exoenzymes; chemical communication; organization of complex ecosystems

(This special issue belongs to the Section Molecular Microbiology)

Cutting-Edge Insights into Bacterial Infection and Host Immune Response

edited by Pablo C. Baldi

submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open

Keywords: bacteria– host interaction; virulence factors; cellular and molecular immune response; immune evasion mechanisms

(This special issue belongs to the Section Molecular Microbiology)

Highlights in Pathophysiology and Treatment of Osteoarthritis

edited by

Antonella Fioravanti

and

Serena Guiducci

submission deadline 31 Dec 2025 | Viewed by 24 | Submission Open

Keywords: osteoarthritis; pathophysiology (cytokines; adipokines; chemokines; epigenetics; microbiome); cartilage; synovial membrane; subchondral bone; treatment; disease-modifying osteoarthritis drugs; non-pharmacological treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Iron in Human Physiology: Molecular Mechanisms and Therapeutic Applications

edited by

Alireza Morovat

submission deadline 31 Dec 2025 | Viewed by 18 | Submission Open

Keywords: iron; hepcidin; ferroportin; ferritin; transferrin; metabolic regulation; cell signaling; cellular processes; mitochondrial function; stress response; inflammation; ferroptosis; gene regulation; disorders

(This special issue belongs to the Section Molecular Biology)

Medicinal Plants in Drug Discovery: Unveiling Potential Applications and Molecular Mechanisms

edited by Abdelhakim Bouyahya

submission deadline 31 Dec 2025 | Viewed by 17 | Submission Open

Keywords: bioactive compounds; pharmacodynamic; clinical efficacy; chemotherapeutic drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Plant RNA Biology: Non Coding RNAs in Plant Development, Defense, and Adaptation

edited by

Andrew Eamens

submission deadline 31 Dec 2025 | Viewed by 7 | Submission Open

Keywords: plant RNA biology; regulatory RNA; non-coding RNA; small RNA (including miRNAs and siRNAs); RNA interacting proteins; plant development; plant pathogen defense; plant environmental stress adaptation

(This special issue belongs to the Section Molecular Plant Sciences)

Poly- and Oligo-Saccharides as Pharmaceutical Agents in Biology and Medicine

edited by

Kevin H. Mayo

submission deadline 1 Jan 2026 | Viewed by 76 | Submission Open

Keywords: polysaccharides; oligosaccharides; isolation and purification; structural and functional analyses; biological mechanisms of action; cellular & molecular targets and interactions; pharmaceutical drug development; cancer; cardiovascular disease; diabetes

(This special issue belongs to the Section Molecular Biology)

From Microbes to Humans: Unveiling the Dynamic World of Carbonic Anhydrases (CAs)

edited by

Clemente Capasso

submission deadline 10 Jan 2026 | Viewed by 478 | Submission Open

Keywords: metalloenzymes; bacteria; pathogens; sulfonamides; inhibitors; activators; anti-infective agents; medicine; anticancer; neurodegenerative diseases; biomedical applications; biotechnology

(This special issue belongs to the Section Biochemistry)

Natural-Derived Bioactive Compounds in Disease Treatment

edited by

Adelina Vlad

and

Marilena Gilca

submission deadline 20 Jan 2026 | 4 articles | Viewed by 10515 | Submission Open

Keywords: medicinal plants; phytochemicals; vitamins; nutraceuticals; anti-oxidants; gene expression; protein expression; cellular signaling; nanoformulations

(This special issue belongs to the Section Molecular Pharmacology)

Renin-Angiotensin System in Health and Diseases

edited by

Keiko Hosohata

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3524 | Submission Open

Keywords: coronavirus disease 2019 (COVID-19); SARS-CoV-2; RAAS; spike protein; angiotensin; ACE2; clinical study; basic experiments

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Breeding and Genetic Regulation of Crops, 2nd Edition

edited by

Chiara Biselli

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1002 | Submission Open

Keywords: molecular breeding; genetic regulation; genomics; genome-editing techniques; epigenetic modifications

(This special issue belongs to the Section Molecular Plant Sciences)

Drug Discovery and Development for Renal Disease Treatment

edited by

Keiko Hosohata

submission deadline 20 Jan 2026 | Viewed by 274 | Submission Open

Keywords: kidney disease; medicinal chemistry; drug discovery; computer-assisted drug design; drug targets; in vitro assays; epigenetic targets; multi-targeting compounds; biophysical methods; target engagement studies

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Animal Reproduction and Development

edited by

Yu-Feng Wang

submission deadline 20 Jan 2026 | Viewed by 223 | Submission Open

Keywords: spermatogenesis; oogenesis; fertilization; embryogenesis; cell division; cell differentiation; stem cell; abnormal development; obesity; cancer

(This special issue belongs to the Section Molecular Biology)

New Advance in Polymers: Structuralization to Functionalization

edited by Wei Wu

submission deadline 25 Jan 2026 | Viewed by 19 | Submission Open

Keywords: polymer material; molecular weight; chain configuration; polymer chains; chemical groups

(This special issue belongs to the Section Materials Science)

Antimicrobial Materials: Molecular Developments and Applications

edited by Florina Iliescu

submission deadline 27 Jan 2026 | Viewed by 27 | Submission Open

Keywords: antimicrobial; polymers; nanotechnology; nanocomposites; molecular; green systems; POC; prophylaxis

(This special issue belongs to the Section Materials Science)

Immunotherapy Versus Immune Modulation of Leukemia

edited by Helga Maria Schmetzer

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4572 | Submission Open

Keywords: leukemia; immunotherapy; immune modulation; antileukemic; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Drug-Induced Modulation and Immunotherapy of Leukemia

edited by Helga Maria Schmetzer

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3416 | Submission Open

Keywords: leukemia; dendritic cells; immunotherapy; immune modulation

(This special issue belongs to the Section Molecular Immunology)

Drug Discovery Based on Natural Products

edited by Woo-kyung Kim

submission deadline 28 Feb 2026 | 4 articles | Viewed by 4997 | Submission Open

Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies

(This special issue belongs to the Section Molecular Pharmacology)

Hormones: Evolutionary and Functional Role

edited by

Giulia Guerriero

submission deadline 20 Mar 2026 | 1 articles | Viewed by 851 | Submission Open

Keywords: hormone action; brain organization; sexual behavior; endocrine tissue; receptor neuroexpression; endocrine control; endocrine disruption; climate change and reproduction; hormones and evolution

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Therapies and Strategies in the Treatment of Neurodegenerative Diseases

edited by

Polina Petkova-Kirova

submission deadline 20 Mar 2026 | 1 articles | Viewed by 621 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; aging; memory; dementia; motor dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Enzyme Inhibitors: Mechanisms, Applications, and Future Perspectives

edited by

Clemente Capasso

and

Valeria Pittalà

submission deadline 30 Mar 2026 | 4 articles | Viewed by 3624 | Submission Open

Keywords: enzyme inhibitors; drug design; drug discovery; drug therapy; resistance mechanisms; cancer; drug delivery systems; biocatalysts; enzymes in industrial applications

(This special issue belongs to the Section Biochemistry)

Research Progress of Orthopedic Materials

edited by Robert Karpiński

submission deadline 20 Apr 2026 | Viewed by 215 | Submission Open

Keywords: biocompatibility; biomaterials; orthopedic implants; hydroxyapatite; biodegradable polymers; tissue engineering; bioactive surfaces; bone cements; bone regeneration; antibacterial coatings

(This special issue belongs to the Section Materials Science)

Displaying special issue 3251-3300 on page 66 of 66.

Go to page 64 65 66

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